Conservation of cofitness between PP_1988 and PP_0417 in Pseudomonas putida KT2440

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_1988 3-isopropylmalate dehydrogenase 1.0 PP_0417 Anthranilate synthase component 1 0.91 9
Pseudomonas fluorescens FW300-N2E2 0.94 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.91 Pf6N2E2_4822 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 103
Pseudomonas fluorescens FW300-N2C3 0.94 AO356_21415 3-isopropylmalate dehydrogenase 0.90 AO356_14420 anthranilate synthase 0.93 13
Pseudomonas fluorescens GW456-L13 0.93 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.88 PfGW456L13_1217 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.89 28
Pseudomonas simiae WCS417 0.93 PS417_18585 3-isopropylmalate dehydrogenase 0.89 PS417_25725 anthranilate synthase component I 0.91 10
Pseudomonas fluorescens SBW25-INTG 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.89 PFLU_RS27380 anthranilate synthase component I 0.44 32
Pseudomonas fluorescens SBW25 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.89 PFLU_RS27380 anthranilate synthase component I 0.50 53
Pseudomonas fluorescens FW300-N1B4 0.93 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.90 Pf1N1B4_2545 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.90 8
Pseudomonas sp. RS175 0.93 PFR28_02821 3-isopropylmalate dehydrogenase 0.90 PFR28_04047 Anthranilate synthase component 1
Pseudomonas fluorescens FW300-N2E3 0.92 AO353_20635 3-isopropylmalate dehydrogenase 0.90 AO353_07230 anthranilate synthase 0.95 9
Pseudomonas syringae pv. syringae B728a 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.87 Psyr_4609 anthranilate synthase, component I 0.93 8
Pseudomonas syringae pv. syringae B728a ΔmexB 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.87 Psyr_4609 anthranilate synthase, component I 0.94 10
Pseudomonas stutzeri RCH2 0.87 Psest_2589 3-isopropylmalate dehydrogenase 0.84 Psest_3650 anthranilate synthase component I, non-proteobacterial lineages 0.84 19
Pseudomonas sp. S08-1 0.87 OH686_04470 3-isopropylmalate dehydrogenase 0.85 OH686_15125 anthranilate synthase component I 0.78 25
Xanthomonas campestris pv. campestris strain 8004 0.81 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.56 Xcc-8004.608.1 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.95 5
Acinetobacter radioresistens SK82 0.73 MPMX26_00348 3-isopropylmalate dehydrogenase 0.50 MPMX26_00199 Anthranilate synthase component 1 0.94 9
Marinobacter adhaerens HP15 0.73 HP15_1832 3-isopropylmalate dehydrogenase 0.65 HP15_3288 anthranilate synthase component I 0.88 13
Dechlorosoma suillum PS 0.68 Dsui_3198 3-isopropylmalate dehydrogenase 0.59 Dsui_0219 anthranilate synthase component I
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS14530 3-isopropylmalate dehydrogenase 0.53 ABZR87_RS02140 anthranilate synthase component I 0.92 8
Paraburkholderia bryophila 376MFSha3.1 0.65 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.53 H281DRAFT_05715 anthranilate synthase, component I 0.73 5
Paraburkholderia graminis OAS925 0.65 ABIE53_004804 3-isopropylmalate dehydrogenase 0.53 ABIE53_003640 anthranilate synthase component 1 0.75 22
Herbaspirillum seropedicae SmR1 0.65 HSERO_RS16500 3-isopropylmalate dehydrogenase 0.54 HSERO_RS19435 anthranilate synthase subunit I 0.92 11
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS14385 3-isopropylmalate dehydrogenase 0.53 RR42_RS18295 anthranilate synthase component I 0.77 21
Variovorax sp. OAS795 0.64 ABID97_RS08455 3-isopropylmalate dehydrogenase 0.52 ABID97_RS05250 anthranilate synthase component I
Ralstonia solanacearum GMI1000 0.64 RS_RS09990 3-isopropylmalate dehydrogenase 0.53 RS_RS14430 anthranilate synthase component I low > 80
Ralstonia solanacearum IBSBF1503 0.64 RALBFv3_RS02610 3-isopropylmalate dehydrogenase 0.53 RALBFv3_RS06485 anthranilate synthase component I low > 76
Ralstonia solanacearum UW163 0.64 UW163_RS11115 3-isopropylmalate dehydrogenase 0.53 UW163_RS07140 anthranilate synthase component I
Variovorax sp. SCN45 0.64 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.52 GFF5896 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.44 94
Burkholderia phytofirmans PsJN 0.64 BPHYT_RS33900 3-isopropylmalate dehydrogenase 0.53 BPHYT_RS17390 anthranilate synthase subunit I 0.95 5
Acidovorax sp. GW101-3H11 0.64 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.54 Ac3H11_767 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.92 10
Paraburkholderia sabiae LMG 24235 0.63 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.54 QEN71_RS27550 anthranilate synthase component I 0.70 43
Ralstonia solanacearum PSI07 0.63 RPSI07_RS14705 3-isopropylmalate dehydrogenase 0.53 RPSI07_RS10755 anthranilate synthase component I
Castellaniella sp019104865 MT123 0.63 ABCV34_RS04280 3-isopropylmalate dehydrogenase 0.51 ABCV34_RS10280 anthranilate synthase component I low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.63 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.53 GFF3106 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.87 9
Desulfovibrio vulgaris Miyazaki F 0.61 DvMF_1794 3-isopropylmalate dehydrogenase (RefSeq) 0.29 DvMF_1746 Anthranilate synthase (RefSeq) 0.81 37
Phaeobacter inhibens DSM 17395 0.60 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.39 PGA1_c16860 anthranilate synthase component 1
Dinoroseobacter shibae DFL-12 0.58 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) 0.41 Dshi_1796 anthranilate synthase component I (RefSeq)
Synechococcus elongatus PCC 7942 0.58 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase 0.39 Synpcc7942_1003 trpE anthranilate synthase, component I
Azospirillum sp. SherDot2 0.57 MPMX19_00607 3-isopropylmalate dehydrogenase 0.41 MPMX19_00893 Anthranilate synthase component 1 low > 112
Desulfovibrio vulgaris Hildenborough JW710 0.57 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) 0.28 DVU0465 trpE anthranilate synthase, component I (TIGR) 0.81 46
Magnetospirillum magneticum AMB-1 0.56 AMB_RS20570 3-isopropylmalate dehydrogenase 0.41 AMB_RS09175 anthranilate synthase component I
Rhodospirillum rubrum S1H 0.56 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) 0.41 Rru_A1891 Anthranilate synthase component I (NCBI) 0.64 50
Sphingomonas koreensis DSMZ 15582 0.56 Ga0059261_3190 3-isopropylmalate dehydrogenase 0.36 Ga0059261_0256 anthranilate synthase component I, non-proteobacterial lineages 0.95 28
Azospirillum brasilense Sp245 0.55 AZOBR_RS14130 3-isopropylmalate dehydrogenase 0.41 AZOBR_RS07490 anthranilate synthase subunit I low > 97
Escherichia coli Nissle 1917 0.54 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.25 ECOLIN_RS07615 anthranilate synthase component I
Escherichia coli ECRC99 0.54 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase 0.25 KEDOAH_26095 trpE anthranilate synthase component I
Escherichia coli ECOR38 0.54 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.25 HEPCGN_25535 trpE anthranilate synthase component I low > 85
Escherichia coli ECRC102 0.54 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase 0.25 NIAGMN_26825 trpE anthranilate synthase component I
Escherichia coli ECRC98 0.54 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase 0.25 JDDGAC_05200 trpE anthranilate synthase component I
Escherichia coli ECRC101 0.54 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.25 MCAODC_15610 trpE anthranilate synthase component I
Escherichia coli ECRC101 0.54 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.25 OKFHMN_02655 trpE anthranilate synthase component I
Escherichia coli BL21 0.54 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.25 ECD_01238 component I of anthranilate synthase 0.50 42
Escherichia coli BW25113 0.54 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.25 b1264 trpE anthranilate synthase component I (NCBI) 0.83 61
Escherichia coli ECOR27 0.54 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.25 NOLOHH_20315 trpE anthranilate synthase component I low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_03584 3-isopropylmalate dehydrogenase 0.25 OHPLBJKB_02419 Anthranilate synthase component 1 low > 73
Shewanella loihica PV-4 0.53 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.25 Shew_2251 anthranilate synthase component I (RefSeq) 0.93 42
Bosea sp. OAE506 0.53 ABIE41_RS11860 3-isopropylmalate dehydrogenase 0.39 ABIE41_RS15730 anthranilate synthase component I
Shewanella sp. ANA-3 0.53 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.26 Shewana3_1520 anthranilate synthase component I (RefSeq) 0.93 20
Shewanella oneidensis MR-1 0.53 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.26 SO3019 trpE anthranilate synthase component I (NCBI ptt file) 0.93 44
Caulobacter crescentus NA1000 0.51 CCNA_00193 3-isopropylmalate dehydrogenase 0.37 CCNA_01972 anthranilate synthase component I 0.91 34
Caulobacter crescentus NA1000 Δfur 0.51 CCNA_00193 3-isopropylmalate dehydrogenase 0.37 CCNA_01972 anthranilate synthase component I low > 67
Mucilaginibacter yixingensis YX-36 DSM 26809 0.49 ABZR88_RS11605 3-isopropylmalate dehydrogenase 0.27 ABZR88_RS16595 anthranilate synthase component I family protein
Lysobacter sp. OAE881 0.49 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.53 ABIE51_RS04150 anthranilate synthase component I low > 62
Pedobacter sp. GW460-11-11-14-LB5 0.49 CA265_RS15850 3-isopropylmalate dehydrogenase 0.27 CA265_RS22890 anthranilate synthase component I 0.78 58
Echinicola vietnamensis KMM 6221, DSM 17526 0.46 Echvi_2062 3-isopropylmalate dehydrogenase 0.25 Echvi_2504 Anthranilate/para-aminobenzoate synthases component I
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.56 LRK54_RS11415 anthranilate synthase component I low > 59
Rhodanobacter denitrificans MT42 0.45 LRK55_RS09965 3-isopropylmalate dehydrogenase 0.56 LRK55_RS11145 anthranilate synthase component I low > 63
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase 0.54 OKGIIK_12405 trpE anthranilate synthase component I low > 52
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.25 HMPREF1078_RS00145 anthranilate synthase component I family protein 0.93 38
Bacteroides stercoris CC31F 0.44 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.26 HMPREF1181_RS15325 anthranilate synthase component I family protein 0.89 31
Brevundimonas sp. GW460-12-10-14-LB2 0.43 A4249_RS09995 3-isopropylmalate dehydrogenase 0.37 A4249_RS06155 anthranilate synthase component I low > 48
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_09445 3-isopropylmalate dehydrogenase 0.25 CA264_05055 anthranilate synthase component I low > 74
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.27 HMPREF1058_RS07175 anthranilate synthase component I family protein 0.83 6
Bacteroides thetaiotaomicron VPI-5482 0.43 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.25 BT0532 anthranilate synthase component I (NCBI ptt file) 0.80 39
Phocaeicola dorei CL03T12C01 0.43 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.26 ABI39_RS21050 anthranilate synthase component I family protein 0.77 33
Bacteroides ovatus ATCC 8483 0.42 BACOVA_04600 3-isopropylmalate dehydrogenase 0.26 BACOVA_03780 chorismate binding enzyme 0.92 40
Dyella japonica UNC79MFTsu3.2 0.42 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.54 ABZR86_RS12180 anthranilate synthase component I 0.94 27
Methanococcus maripaludis JJ 0.29 MMJJ_RS02220 3-isopropylmalate dehydrogenase 0.27 MMJJ_RS09175 anthranilate synthase component I
Methanococcus maripaludis S2 0.28 MMP_RS02855 3-isopropylmalate dehydrogenase 0.27 MMP_RS05205 anthranilate synthase component I
Mycobacterium tuberculosis H37Rv 0.27 Rv2995c Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.37 Rv1609 Anthranilate synthase component I TrpE (glutamine amidotransferase)
Bifidobacterium breve UCC2003 0.25 BBR_RS12870 3-isopropylmalate dehydrogenase 0.38 BBR_RS16085 anthranilate synthase component I low > 34

Not shown: 22 genomes with orthologs for PP_1988 only; 0 genomes with orthologs for PP_0417 only