Conservation of cofitness between PP_1985 and PP_0417 in Pseudomonas putida KT2440

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_1985 3-isopropylmalate dehydratase large subunit 1.0 PP_0417 Anthranilate synthase component 1 0.89 9
Pseudomonas fluorescens FW300-N1B4 0.90 Pf1N1B4_15 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.90 Pf1N1B4_2545 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.89 10
Pseudomonas fluorescens GW456-L13 0.90 PfGW456L13_3948 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.88 PfGW456L13_1217 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.87 34
Pseudomonas fluorescens FW300-N2E2 0.89 Pf6N2E2_63 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.91 Pf6N2E2_4822 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 103
Pseudomonas fluorescens FW300-N2C3 0.89 AO356_21400 isopropylmalate isomerase 0.90 AO356_14420 anthranilate synthase 0.92 13
Pseudomonas fluorescens FW300-N2E3 0.89 AO353_20620 isopropylmalate isomerase 0.90 AO353_07230 anthranilate synthase 0.94 9
Pseudomonas sp. RS175 0.89 PFR28_02824 3-isopropylmalate dehydratase large subunit 0.90 PFR28_04047 Anthranilate synthase component 1
Pseudomonas simiae WCS417 0.89 PS417_18600 isopropylmalate isomerase 0.89 PS417_25725 anthranilate synthase component I 0.89 11
Pseudomonas fluorescens SBW25-INTG 0.89 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.89 PFLU_RS27380 anthranilate synthase component I 0.45 31
Pseudomonas fluorescens SBW25 0.89 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.89 PFLU_RS27380 anthranilate synthase component I 0.50 50
Pseudomonas stutzeri RCH2 0.88 Psest_2591 3-isopropylmalate dehydratase, large subunit 0.84 Psest_3650 anthranilate synthase component I, non-proteobacterial lineages 0.82 19
Pseudomonas syringae pv. syringae B728a ΔmexB 0.87 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.87 Psyr_4609 anthranilate synthase, component I 0.93 8
Pseudomonas syringae pv. syringae B728a 0.87 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.87 Psyr_4609 anthranilate synthase, component I 0.91 11
Pseudomonas sp. S08-1 0.86 OH686_04480 3-isopropylmalate dehydratase large subunit 0.85 OH686_15125 anthranilate synthase component I 0.72 33
Xanthomonas campestris pv. campestris strain 8004 0.84 Xcc-8004.1049.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.56 Xcc-8004.608.1 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.95 4
Marinobacter adhaerens HP15 0.78 HP15_1834 protein containing 3-isopropylmalate dehydratase, large subunit region domain 0.65 HP15_3288 anthranilate synthase component I 0.89 13
Acinetobacter radioresistens SK82 0.72 MPMX26_00345 3-isopropylmalate dehydratase large subunit 0.50 MPMX26_00199 Anthranilate synthase component 1 0.95 8
Ralstonia sp. UNC404CL21Col 0.72 ABZR87_RS14540 3-isopropylmalate dehydratase large subunit 0.53 ABZR87_RS02140 anthranilate synthase component I 0.88 11
Castellaniella sp019104865 MT123 0.72 ABCV34_RS04290 3-isopropylmalate dehydratase large subunit 0.51 ABCV34_RS10280 anthranilate synthase component I low > 48
Cupriavidus basilensis FW507-4G11 0.72 RR42_RS14400 isopropylmalate isomerase 0.53 RR42_RS18295 anthranilate synthase component I 0.77 24
Ralstonia solanacearum PSI07 0.72 RPSI07_RS14695 3-isopropylmalate dehydratase large subunit 0.53 RPSI07_RS10755 anthranilate synthase component I
Ralstonia solanacearum GMI1000 0.72 RS_RS10000 3-isopropylmalate dehydratase large subunit 0.53 RS_RS14430 anthranilate synthase component I 0.39 33
Ralstonia solanacearum UW163 0.71 UW163_RS11105 3-isopropylmalate dehydratase large subunit 0.53 UW163_RS07140 anthranilate synthase component I
Ralstonia solanacearum IBSBF1503 0.71 RALBFv3_RS02620 3-isopropylmalate dehydratase large subunit 0.53 RALBFv3_RS06485 anthranilate synthase component I low > 76
Paraburkholderia sabiae LMG 24235 0.71 QEN71_RS17605 3-isopropylmalate dehydratase large subunit 0.54 QEN71_RS27550 anthranilate synthase component I 0.75 40
Paraburkholderia bryophila 376MFSha3.1 0.71 H281DRAFT_06075 3-isopropylmalate dehydratase, large subunit 0.53 H281DRAFT_05715 anthranilate synthase, component I 0.69 7
Burkholderia phytofirmans PsJN 0.71 BPHYT_RS33915 isopropylmalate isomerase 0.53 BPHYT_RS17390 anthranilate synthase subunit I 0.94 5
Herbaspirillum seropedicae SmR1 0.71 HSERO_RS16515 isopropylmalate isomerase 0.54 HSERO_RS19435 anthranilate synthase subunit I 0.92 15
Paraburkholderia graminis OAS925 0.71 ABIE53_004801 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit 0.53 ABIE53_003640 anthranilate synthase component 1 0.72 22
Variovorax sp. OAS795 0.69 ABID97_RS08465 3-isopropylmalate dehydratase large subunit 0.52 ABID97_RS05250 anthranilate synthase component I
Variovorax sp. SCN45 0.68 GFF3890 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.52 GFF5896 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.57 50
Hydrogenophaga sp. GW460-11-11-14-LB1 0.67 GFF3363 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.53 GFF3106 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.82 10
Acidovorax sp. GW101-3H11 0.67 Ac3H11_1525 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.54 Ac3H11_767 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.94 9
Azospirillum brasilense Sp245 0.66 AZOBR_RS03545 isopropylmalate isomerase 0.41 AZOBR_RS07490 anthranilate synthase subunit I low > 97
Azospirillum sp. SherDot2 0.66 MPMX19_01998 3-isopropylmalate dehydratase large subunit 0.41 MPMX19_00893 Anthranilate synthase component 1 low > 112
Rhodospirillum rubrum S1H 0.66 Rru_A1189 3-isopropylmalate dehydratase large subunit region (NCBI) 0.41 Rru_A1891 Anthranilate synthase component I (NCBI) 0.64 47
Dechlorosoma suillum PS 0.66 Dsui_3201 3-isopropylmalate dehydratase, large subunit 0.59 Dsui_0219 anthranilate synthase component I
Bosea sp. OAE506 0.63 ABIE41_RS11660 3-isopropylmalate dehydratase large subunit 0.39 ABIE41_RS15730 anthranilate synthase component I
Magnetospirillum magneticum AMB-1 0.63 AMB_RS20560 3-isopropylmalate dehydratase large subunit 0.41 AMB_RS09175 anthranilate synthase component I
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_00196 3-isopropylmalate dehydratase large subunit 0.37 CCNA_01972 anthranilate synthase component I low > 67
Caulobacter crescentus NA1000 0.61 CCNA_00196 3-isopropylmalate dehydratase large subunit 0.37 CCNA_01972 anthranilate synthase component I 0.91 34
Escherichia coli ECOR38 0.61 HEPCGN_08705 leuC1 3-isopropylmalate dehydratase large subunit 1 0.25 HEPCGN_25535 trpE anthranilate synthase component I low > 85
Escherichia coli BW25113 0.61 b0072 leuC isopropylmalate isomerase large subunit (NCBI) 0.25 b1264 trpE anthranilate synthase component I (NCBI) 0.84 60
Escherichia coli Nissle 1917 0.61 ECOLIN_RS00390 3-isopropylmalate dehydratase large subunit 0.25 ECOLIN_RS07615 anthranilate synthase component I
Escherichia coli BL21 0.61 ECD_00074 3-isopropylmalate dehydratase large subunit 0.25 ECD_01238 component I of anthranilate synthase low > 60
Escherichia coli ECRC99 0.61 KEDOAH_17430 leuC1 3-isopropylmalate dehydratase large subunit 1 0.25 KEDOAH_26095 trpE anthranilate synthase component I
Escherichia coli ECRC101 0.61 MCAODC_01240 leuC1 3-isopropylmalate dehydratase large subunit 1 0.25 MCAODC_15610 trpE anthranilate synthase component I
Escherichia coli ECRC102 0.61 NIAGMN_08575 leuC1 3-isopropylmalate dehydratase large subunit 1 0.25 NIAGMN_26825 trpE anthranilate synthase component I
Escherichia coli ECRC101 0.61 OKFHMN_10725 leuC1 3-isopropylmalate dehydratase large subunit 1 0.25 OKFHMN_02655 trpE anthranilate synthase component I
Escherichia coli ECOR27 0.61 NOLOHH_03070 leuC1 3-isopropylmalate dehydratase large subunit 1 0.25 NOLOHH_20315 trpE anthranilate synthase component I low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.61 OHPLBJKB_03585 3-isopropylmalate dehydratase large subunit 0.25 OHPLBJKB_02419 Anthranilate synthase component 1 low > 73
Escherichia coli ECRC98 0.61 JDDGAC_14320 leuC1 3-isopropylmalate dehydratase large subunit 1 0.25 JDDGAC_05200 trpE anthranilate synthase component I
Rhodanobacter denitrificans MT42 0.60 LRK55_RS07105 3-isopropylmalate dehydratase large subunit 0.56 LRK55_RS11145 anthranilate synthase component I low > 63
Rhodanobacter denitrificans FW104-10B01 0.60 LRK54_RS07375 3-isopropylmalate dehydratase large subunit 0.56 LRK54_RS11415 anthranilate synthase component I low > 59
Shewanella oneidensis MR-1 0.59 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) 0.26 SO3019 trpE anthranilate synthase component I (NCBI ptt file) 0.92 44
Shewanella loihica PV-4 0.59 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) 0.25 Shew_2251 anthranilate synthase component I (RefSeq) 0.93 43
Phaeobacter inhibens DSM 17395 0.59 PGA1_c29780 3-isopropylmalate dehydratase large subunit 0.39 PGA1_c16860 anthranilate synthase component 1
Shewanella sp. ANA-3 0.59 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) 0.26 Shewana3_1520 anthranilate synthase component I (RefSeq) 0.94 18
Dinoroseobacter shibae DFL-12 0.59 Dshi_0085 3-isopropylmalate dehydratase, large subunit (RefSeq) 0.41 Dshi_1796 anthranilate synthase component I (RefSeq)
Sphingomonas koreensis DSMZ 15582 0.58 Ga0059261_4223 3-isopropylmalate dehydratase, large subunit 0.36 Ga0059261_0256 anthranilate synthase component I, non-proteobacterial lineages 0.96 35
Mycobacterium tuberculosis H37Rv 0.56 Rv2988c Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) 0.37 Rv1609 Anthranilate synthase component I TrpE (glutamine amidotransferase)
Bifidobacterium breve UCC2003 0.54 BBR_RS19630 3-isopropylmalate dehydratase large subunit 0.38 BBR_RS16085 anthranilate synthase component I low > 34
Pontibacter actiniarum KMM 6156, DSM 19842 0.52 CA264_09435 3-isopropylmalate dehydratase large subunit 0.25 CA264_05055 anthranilate synthase component I low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.52 ABZR88_RS11595 3-isopropylmalate dehydratase large subunit 0.27 ABZR88_RS16595 anthranilate synthase component I family protein
Pedobacter sp. GW460-11-11-14-LB5 0.51 CA265_RS15830 3-isopropylmalate dehydratase large subunit 0.27 CA265_RS22890 anthranilate synthase component I 0.75 63
Parabacteroides merdae CL09T00C40 0.50 HMPREF1078_RS16660 3-isopropylmalate dehydratase large subunit 0.25 HMPREF1078_RS00145 anthranilate synthase component I family protein 0.95 28
Bacteroides stercoris CC31F 0.50 HMPREF1181_RS14145 3-isopropylmalate dehydratase large subunit 0.26 HMPREF1181_RS15325 anthranilate synthase component I family protein 0.90 35
Phocaeicola dorei CL03T12C01 0.50 ABI39_RS10200 3-isopropylmalate dehydratase large subunit 0.26 ABI39_RS21050 anthranilate synthase component I family protein 0.78 41
Phocaeicola vulgatus CL09T03C04 0.50 HMPREF1058_RS14550 3-isopropylmalate dehydratase large subunit 0.27 HMPREF1058_RS07175 anthranilate synthase component I family protein 0.87 6
Bacteroides thetaiotaomicron VPI-5482 0.49 BT1860 3-isopropylmalate dehydratase large subunit (NCBI ptt file) 0.25 BT0532 anthranilate synthase component I (NCBI ptt file) 0.83 37
Bacteroides ovatus ATCC 8483 0.49 BACOVA_04603 3-isopropylmalate dehydratase, large subunit 0.26 BACOVA_03780 chorismate binding enzyme 0.92 44
Echinicola vietnamensis KMM 6221, DSM 17526 0.49 Echvi_2059 3-isopropylmalate dehydratase, large subunit 0.25 Echvi_2504 Anthranilate/para-aminobenzoate synthases component I 0.55 53
Dyella japonica UNC79MFTsu3.2 0.48 ABZR86_RS15960 3-isopropylmalate dehydratase large subunit 0.54 ABZR86_RS12180 anthranilate synthase component I 0.95 23
Lysobacter sp. OAE881 0.48 ABIE51_RS17575 3-isopropylmalate dehydratase large subunit 0.53 ABIE51_RS04150 anthranilate synthase component I 0.85 59
Brevundimonas sp. GW460-12-10-14-LB2 0.48 A4249_RS10005 3-isopropylmalate dehydratase large subunit 0.37 A4249_RS06155 anthranilate synthase component I low > 48
Rhodanobacter sp. FW510-T8 0.47 OKGIIK_13585 leuC 3-isopropylmalate dehydratase large subunit 0.54 OKGIIK_12405 trpE anthranilate synthase component I low > 52
Synechococcus elongatus PCC 7942 0.46 Synpcc7942_1898 leuC isopropylmalate isomerase large subunit 0.39 Synpcc7942_1003 trpE anthranilate synthase, component I
Methanococcus maripaludis JJ 0.22 MMJJ_RS06750 homoaconitase large subunit 0.27 MMJJ_RS09175 anthranilate synthase component I low > 28
Methanococcus maripaludis S2 0.22 MMP_RS07610 homoaconitase large subunit 0.27 MMP_RS05205 anthranilate synthase component I
Desulfovibrio vulgaris Miyazaki F 0.20 DvMF_1792 3-isopropylmalate dehydratase large subunit (RefSeq) 0.29 DvMF_1746 Anthranilate synthase (RefSeq) 0.84 34
Desulfovibrio vulgaris Hildenborough JW710 0.20 DVU2982 leuC 3-isopropylmalate dehydratase / (R)-citramalate isomerase, large subunit LeuC (EC 4.2.1.33; EC 4.2.1.35) (from data) 0.28 DVU0465 trpE anthranilate synthase, component I (TIGR) 0.81 45

Not shown: 22 genomes with orthologs for PP_1985 only; 0 genomes with orthologs for PP_0417 only