Conservation of cofitness between OKFHMN_13315 and OKFHMN_13375 in Escherichia coli ECRC100

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC100 1.0 OKFHMN_13315 purD Phosphoribosylamine--glycine ligase 1.0 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.87 18
Escherichia coli ECRC101 1.00 MCAODC_03815 purD Phosphoribosylamine--glycine ligase 1.00 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC low > 87
Escherichia coli ECRC102 1.00 NIAGMN_11065 purD Phosphoribosylamine--glycine ligase 1.00 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC99 1.00 KEDOAH_14845 purD Phosphoribosylamine--glycine ligase 1.00 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC98 1.00 JDDGAC_16940 purD Phosphoribosylamine--glycine ligase 1.00 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC low > 86
Escherichia coli ECRC62 0.99 BNILDI_06060 purD Phosphoribosylamine--glycine ligase 0.99 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.86 30
Escherichia coli Nissle 1917 0.99 ECOLIN_RS23095 phosphoribosylamine--glycine ligase 0.99 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.80 14
Escherichia coli ECOR27 0.99 NOLOHH_05460 purD Phosphoribosylamine--glycine ligase 0.99 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC low > 75
Escherichia fergusonii Becca 0.99 EFB2_04605 Phosphoribosylamine--glycine ligase 0.99 EFB2_04617 Phosphomethylpyrimidine synthase low > 86
Escherichia coli ECOR38 0.99 HEPCGN_11955 purD Phosphoribosylamine--glycine ligase 0.99 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.92 16
Escherichia coli BL21 0.99 ECD_03882 phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase 1.00 ECD_03871 phosphomethylpyrimidine synthase 0.65 32
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_04044 Phosphoribosylamine--glycine ligase 0.99 OHPLBJKB_04056 Phosphomethylpyrimidine synthase low > 73
Escherichia coli BW25113 0.98 b4005 purD phosphoribosylamine--glycine ligase (NCBI) 0.99 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF4187 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.95 GFF4198 Thiamin biosynthesis protein ThiC low > 78
Klebsiella michiganensis M5al 0.92 BWI76_RS01610 phosphoribosylamine--glycine ligase 0.93 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC low > 92
Enterobacter sp. TBS_079 0.92 MPMX20_00225 Phosphoribosylamine--glycine ligase 0.96 MPMX20_00217 Phosphomethylpyrimidine synthase low > 85
Enterobacter asburiae PDN3 0.92 EX28DRAFT_4544 phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.95 EX28DRAFT_4536 phosphomethylpyrimidine synthase low > 76
Pantoea sp. MT58 0.84 IAI47_18045 phosphoribosylamine--glycine ligase 0.84 IAI47_18085 phosphomethylpyrimidine synthase ThiC low > 76
Dickeya dadantii 3937 0.83 DDA3937_RS01215 phosphoribosylamine--glycine ligase 0.85 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC low > 74
Dickeya dianthicola ME23 0.83 DZA65_RS01255 phosphoribosylamine--glycine ligase 0.86 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC low > 75
Dickeya dianthicola 67-19 0.83 HGI48_RS01210 phosphoribosylamine--glycine ligase 0.84 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC low > 71
Rahnella sp. WP5 0.82 EX31_RS16855 phosphoribosylamine--glycine ligase 0.86 EX31_RS16815 phosphomethylpyrimidine synthase ThiC low > 89
Pectobacterium carotovorum WPP14 0.82 HER17_RS20340 phosphoribosylamine--glycine ligase 0.87 HER17_RS20380 phosphomethylpyrimidine synthase ThiC low > 75
Erwinia tracheiphila SCR3 0.81 LU632_RS01015 purD phosphoribosylamine--glycine ligase 0.83 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC low > 74
Serratia liquefaciens MT49 0.81 IAI46_01360 phosphoribosylamine--glycine ligase 0.84 IAI46_01320 phosphomethylpyrimidine synthase ThiC low > 86
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_01415 phosphoribosylamine--glycine ligase 0.74 CSW01_00335 phosphomethylpyrimidine synthase low > 62
Marinobacter adhaerens HP15 0.74 HP15_3228 phosphoribosylamine-glycine ligase 0.70 HP15_453 thiamine biosynthesis protein thiC — —
Pseudomonas putida KT2440 0.74 PP_4823 Phosphoribosylamine--glycine ligase 0.72 PP_4922 Phosphomethylpyrimidine synthase — —
Pseudomonas sp. RS175 0.73 PFR28_05213 Phosphoribosylamine--glycine ligase 0.72 PFR28_05091 Phosphomethylpyrimidine synthase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.73 Psyr_4407 phosphoribosylamine--glycine ligase 0.71 Psyr_0544 hydroxymethylpyrimidine synthase — —
Pseudomonas syringae pv. syringae B728a 0.73 Psyr_4407 phosphoribosylamine--glycine ligase 0.71 Psyr_0544 hydroxymethylpyrimidine synthase low > 86
Pseudomonas fluorescens FW300-N2E2 0.73 Pf6N2E2_3520 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.71 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Pseudomonas fluorescens FW300-N2C3 0.73 AO356_08230 phosphoribosylamine--glycine ligase 0.71 AO356_08810 thiamine biosynthesis protein ThiC — —
Pseudomonas fluorescens FW300-N2E3 0.73 AO353_13645 phosphoribosylamine--glycine ligase 0.71 AO353_13010 thiamine biosynthesis protein ThiC — —
Pseudomonas stutzeri RCH2 0.73 Psest_1013 phosphoribosylamine--glycine ligase 0.71 Psest_0477 thiamine biosynthesis protein ThiC low > 67
Pseudomonas fluorescens SBW25-INTG 0.73 PFLU_RS03010 phosphoribosylamine--glycine ligase 0.71 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC — —
Pseudomonas fluorescens SBW25 0.73 PFLU_RS03010 phosphoribosylamine--glycine ligase 0.71 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC — —
Pseudomonas fluorescens FW300-N1B4 0.73 Pf1N1B4_1316 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.71 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Pseudomonas sp. S08-1 0.73 OH686_07625 Phosphoribosylamine--glycine ligase 0.71 OH686_15885 phosphomethylpyrimidine synthase — —
Alteromonas macleodii MIT1002 0.73 MIT1002_03961 Phosphoribosylamine--glycine ligase 0.75 MIT1002_00097 Phosphomethylpyrimidine synthase low > 70
Pseudomonas fluorescens GW456-L13 0.72 PfGW456L13_58 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.71 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Pseudomonas simiae WCS417 0.72 PS417_02935 phosphoribosylamine--glycine ligase 0.71 PS417_02355 thiamine biosynthesis protein ThiC — —
Shewanella amazonensis SB2B 0.72 Sama_0394 phosphoribosylamine--glycine ligase (RefSeq) 0.77 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) low > 62
Kangiella aquimarina DSM 16071 0.71 B158DRAFT_0167 phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.67 B158DRAFT_0295 hydroxymethylpyrimidine synthase — —
Shewanella sp. ANA-3 0.70 Shewana3_0440 phosphoribosylamine--glycine ligase (RefSeq) 0.74 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) low > 73
Shewanella oneidensis MR-1 0.69 SO0441 purD phosphoribosylamine--glycine ligase (NCBI ptt file) 0.75 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.67 Shew_3413 phosphoribosylamine--glycine ligase (RefSeq) 0.77 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) low > 60
Xanthomonas campestris pv. campestris strain 8004 0.67 Xcc-8004.657.1 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.67 Xcc-8004.1066.1 hypothetical protein low > 74
Dyella japonica UNC79MFTsu3.2 0.65 ABZR86_RS13850 phosphoribosylamine--glycine ligase 0.69 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC low > 74
Acinetobacter radioresistens SK82 0.65 MPMX26_01140 Phosphoribosylamine--glycine ligase 0.69 MPMX26_00180 Phosphomethylpyrimidine synthase low > 36
Lysobacter sp. OAE881 0.63 ABIE51_RS17770 phosphoribosylamine--glycine ligase 0.68 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC low > 62
Rhodanobacter sp. FW510-T8 0.63 OKGIIK_13750 purD phosphoribosylamine--glycine ligase 0.68 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC low > 52
Dechlorosoma suillum PS 0.62 Dsui_1596 phosphoribosylamine--glycine ligase 0.69 Dsui_0422 thiamine biosynthesis protein ThiC — —
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS17755 phosphoribosylamine--glycine ligase 0.69 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC — —
Paraburkholderia bryophila 376MFSha3.1 0.60 H281DRAFT_04521 phosphoribosylamine--glycine ligase 0.68 H281DRAFT_00395 hydroxymethylpyrimidine synthase — —
Paraburkholderia graminis OAS925 0.60 ABIE53_001545 phosphoribosylamine--glycine ligase 0.68 ABIE53_002857 phosphomethylpyrimidine synthase — —
Burkholderia phytofirmans PsJN 0.59 BPHYT_RS06405 phosphoribosylamine--glycine ligase 0.68 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.63 96
Ralstonia solanacearum GMI1000 0.59 RS_RS10995 phosphoribosylamine--glycine ligase 0.68 RS_RS00555 phosphomethylpyrimidine synthase — —
Ralstonia solanacearum PSI07 0.59 RPSI07_RS13680 phosphoribosylamine--glycine ligase 0.68 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC — —
Paraburkholderia sabiae LMG 24235 0.59 QEN71_RS24400 phosphoribosylamine--glycine ligase 0.69 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.70 41
Acidovorax sp. GW101-3H11 0.59 Ac3H11_2421 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.63 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Ralstonia sp. UNC404CL21Col 0.58 ABZR87_RS15410 phosphoribosylamine--glycine ligase 0.68 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC — —
Ralstonia solanacearum UW163 0.58 UW163_RS10125 phosphoribosylamine--glycine ligase 0.68 UW163_RS03640 phosphomethylpyrimidine synthase ThiC — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.58 GFF4524 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.64 GFF166 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS03545 phosphoribosylamine--glycine ligase 0.68 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC — —
Castellaniella sp019104865 MT123 0.57 ABCV34_RS02550 phosphoribosylamine--glycine ligase 0.69 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC — —
Cupriavidus basilensis FW507-4G11 0.57 RR42_RS04730 phosphoribosylamine--glycine ligase 0.67 RR42_RS01290 thiamine biosynthesis protein ThiC — —
Variovorax sp. SCN45 0.57 GFF302 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.63 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) low > 127
Variovorax sp. OAS795 0.56 ABID97_RS16735 phosphoribosylamine--glycine ligase 0.63 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC — —
Agrobacterium fabrum C58 0.55 Atu0647 phosphoribosylamine--glycine ligase 0.64 Atu2569 thiamine biosynthesis protein 0.68 68
Azospirillum sp. SherDot2 0.53 MPMX19_01630 Phosphoribosylamine--glycine ligase 0.63 MPMX19_00336 Phosphomethylpyrimidine synthase low > 112
Azospirillum brasilense Sp245 0.53 AZOBR_RS04470 phosphoribosylamine--glycine ligase 0.65 AZOBR_RS07940 phosphomethylpyrimidine synthase — —
Rhodopseudomonas palustris CGA009 0.53 TX73_005965 phosphoribosylamine--glycine ligase 0.60 TX73_018540 phosphomethylpyrimidine synthase ThiC — —
Magnetospirillum magneticum AMB-1 0.53 AMB_RS01075 phosphoribosylamine--glycine ligase 0.65 AMB_RS01125 phosphomethylpyrimidine synthase — —
Sinorhizobium meliloti 1021 0.52 SMc00993 phosphoribosylamine--glycine ligase 0.63 SM_b20615 thiamine biosynthesis protein ThiC low > 103
Bosea sp. OAE506 0.50 ABIE41_RS23160 phosphoribosylamine--glycine ligase 0.60 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.80 4
Rhodospirillum rubrum S1H 0.48 Rru_A0646 Phosphoribosylamine--glycine ligase (NCBI) 0.59 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) — —
Phaeobacter inhibens DSM 17395 0.47 PGA1_c23610 phosphoribosylamine--glycine ligase PurD 0.64 PGA1_c09110 thiamine biosynthesis protein ThiC low > 62
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS06805 phosphoribosylamine--glycine ligase 0.57 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC low > 61
Dinoroseobacter shibae DFL-12 0.45 Dshi_2728 phosphoribosylamine--glycine ligase (RefSeq) 0.64 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) — —
Phocaeicola vulgatus CL09T03C04 0.44 HMPREF1058_RS10995 phosphoribosylamine--glycine ligase 0.57 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC low > 67
Sphingomonas koreensis DSMZ 15582 0.44 Ga0059261_1441 phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.62 Ga0059261_2424 hydroxymethylpyrimidine synthase — —
Bacteroides stercoris CC31F 0.44 HMPREF1181_RS01580 phosphoribosylamine--glycine ligase 0.56 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC low > 56
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_0167 phosphoribosylamine--glycine ligase 0.69 Echvi_3567 thiamine biosynthesis protein ThiC — —
Brevundimonas sp. GW460-12-10-14-LB2 0.44 A4249_RS09255 phosphoribosylamine--glycine ligase 0.62 A4249_RS15715 phosphomethylpyrimidine synthase ThiC low > 48
Phocaeicola dorei CL03T12C01 0.44 ABI39_RS06055 phosphoribosylamine--glycine ligase 0.57 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC low > 72
Caulobacter crescentus NA1000 0.44 CCNA_00299 phosphoribosylamine--glycine ligase 0.64 CCNA_02109 thiamine biosynthesis protein thiC low > 66
Caulobacter crescentus NA1000 Δfur 0.44 CCNA_00299 phosphoribosylamine--glycine ligase 0.64 CCNA_02109 thiamine biosynthesis protein thiC low > 67
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS01620 phosphoribosylamine--glycine ligase 0.70 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC — —
Bacteroides thetaiotaomicron VPI-5482 0.43 BT3253 phosphoribosylamine--glycine ligase (NCBI ptt file) 0.57 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.43 BACOVA_01348 phosphoribosylamine--glycine ligase 0.56 BACOVA_02358 thiamine biosynthesis protein ThiC 0.74 68
Pontibacter actiniarum KMM 6156, DSM 19842 0.42 CA264_20115 phosphoribosylamine--glycine ligase 0.70 CA264_20435 phosphomethylpyrimidine synthase ThiC low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.39 CA265_RS22605 phosphoribosylamine--glycine ligase 0.68 CA265_RS20165 phosphomethylpyrimidine synthase ThiC — —
Mycobacterium tuberculosis H37Rv 0.35 Rv0772 Probable phosphoribosylamine--glycine ligase PurD (GARS) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase) (5'-phosphoribosylglycinamide synthetase) 0.51 Rv0423c Probable thiamine biosynthesis protein ThiC — —

Not shown: 10 genomes with orthologs for OKFHMN_13315 only; 0 genomes with orthologs for OKFHMN_13375 only