Conservation of cofitness between HER17_RS02805 and HER17_RS12005 in Pectobacterium carotovorum WPP14

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS02805 threonine synthase 1.0 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.95 6
Dickeya dadantii 3937 0.88 DDA3937_RS18405 threonine synthase 0.91 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase low > 74
Dickeya dianthicola 67-19 0.87 HGI48_RS18335 threonine synthase 0.90 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.71 11
Dickeya dianthicola ME23 0.87 DZA65_RS19475 threonine synthase 0.90 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.58 45
Rahnella sp. WP5 0.86 EX31_RS03935 threonine synthase 0.88 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.94 48
Serratia liquefaciens MT49 0.86 IAI46_03040 threonine synthase 0.91 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.81 20
Pantoea sp. MT58 0.83 IAI47_16205 threonine synthase 0.82 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.76 75
Erwinia tracheiphila SCR3 0.82 LU632_RS02620 thrC threonine synthase 0.79 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Enterobacter asburiae PDN3 0.82 EX28DRAFT_3616 threonine synthase 0.85 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Enterobacter sp. TBS_079 0.82 MPMX20_00712 Threonine synthase 0.85 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.80 60
Klebsiella michiganensis M5al 0.81 BWI76_RS04255 threonine synthase 0.86 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.61 76
Escherichia coli ECRC98 0.79 JDDGAC_14695 thrC threonine synthase 0.86 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase low > 86
Escherichia coli ECRC100 0.79 OKFHMN_11100 thrC threonine synthase 0.86 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 0.84 77
Escherichia coli ECRC99 0.79 KEDOAH_17055 thrC threonine synthase 0.86 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECOR27 0.79 NOLOHH_03430 thrC threonine synthase 0.86 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia coli ECRC102 0.79 NIAGMN_08950 thrC threonine synthase 0.86 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECOR38 0.79 HEPCGN_09105 thrC threonine synthase 0.86 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 0.78 83
Escherichia coli ECRC62 0.79 BNILDI_08170 thrC threonine synthase 0.86 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia fergusonii Becca 0.79 EFB2_04039 Threonine synthase 0.86 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Escherichia coli ECRC101 0.79 MCAODC_01615 thrC threonine synthase 0.86 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.70 74
Escherichia coli BL21 0.79 ECD_00004 L-threonine synthase 0.86 ECD_00949 dihydro-orotate oxidase, FMN-linked low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.79 OHPLBJKB_03656 Threonine synthase 0.86 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) low > 73
Escherichia coli BW25113 0.79 b0004 thrC threonine synthase (NCBI) 0.86 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.78 70
Escherichia coli Nissle 1917 0.79 ECOLIN_RS00020 threonine synthase 0.86 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.79 GFF1080 Threonine synthase (EC 4.2.3.1) 0.85 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 78
Vibrio cholerae E7946 ATCC 55056 0.69 CSW01_11965 threonine synthase 0.72 CSW01_07490 dihydroorotate dehydrogenase (quinone) low > 62
Alteromonas macleodii MIT1002 0.62 MIT1002_03084 Threonine synthase 0.59 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.83 60
Shewanella loihica PV-4 0.58 Shew_1081 threonine synthase (RefSeq) 0.62 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) low > 60
Shewanella sp. ANA-3 0.55 Shewana3_1141 threonine synthase (RefSeq) 0.64 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.86 71
Shewanella oneidensis MR-1 0.55 SO3413 thrC threonine synthase (NCBI ptt file) 0.63 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.55 Sama_0907 threonine synthase (RefSeq) 0.64 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) low > 62
Bacteroides thetaiotaomicron VPI-5482 0.42 BT2401 threonine synthase (NCBI ptt file) 0.25 BT1009 dihydroorotate dehydrogenase (NCBI ptt file) low > 81
Echinicola vietnamensis KMM 6221, DSM 17526 0.39 Echvi_2002 threonine synthase 0.42 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.37 ABZR88_RS18960 threonine synthase 0.41 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.37 CA265_RS23465 threonine synthase 0.42 CA265_RS14005 dihydroorotate dehydrogenase (quinone) — —
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.2954.1 Threonine synthase (EC 4.2.3.1) 0.47 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Phaeobacter inhibens DSM 17395 0.29 PGA1_c06310 threonine synthase ThrC 0.34 PGA1_c12150 dihydroorotate dehydrogenase PyrD — —
Lysobacter sp. OAE881 0.29 ABIE51_RS17530 threonine synthase 0.44 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.28 Pf6N2E2_3142 Threonine synthase (EC 4.2.3.1) 0.55 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2C3 0.28 AO356_06370 threonine synthase 0.55 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens FW300-N2E3 0.28 AO353_04350 threonine synthase 0.55 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas putida KT2440 0.28 PP_1471 Threonine synthase 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas syringae pv. syringae B728a 0.28 Psyr_1291 L-threonine synthase 0.56 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.28 Psyr_1291 L-threonine synthase 0.56 Psyr_2106 dihydroorotate oxidase A — —
Rhodanobacter denitrificans MT42 0.28 LRK55_RS09995 threonine synthase 0.48 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.28 LRK54_RS10355 threonine synthase 0.48 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas sp. S08-1 0.28 OH686_17765 threonine synthase 0.55 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Pseudomonas fluorescens FW300-N1B4 0.28 Pf1N1B4_3014 Threonine synthase (EC 4.2.3.1) 0.56 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens GW456-L13 0.28 PfGW456L13_1724 Threonine synthase (EC 4.2.3.1) 0.55 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas simiae WCS417 0.28 PS417_22880 threonine synthase 0.56 PS417_20935 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.27 PFLU_RS24545 threonine synthase 0.56 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.27 PFLU_RS24545 threonine synthase 0.56 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas sp. RS175 0.27 PFR28_00334 Threonine synthase 0.56 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Dyella japonica UNC79MFTsu3.2 0.27 ABZR86_RS15975 threonine synthase (EC 4.2.3.1) (from data) 0.49 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.27 OKGIIK_13570 thrC threonine synthase 0.48 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Caulobacter crescentus NA1000 Δfur 0.27 CCNA_03510 threonine synthase 0.33 CCNA_00562 dihydroorotate dehydrogenase — —
Bosea sp. OAE506 0.27 ABIE41_RS22985 threonine synthase 0.34 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas stutzeri RCH2 0.27 Psest_3125 threonine synthase 0.54 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 — —
Caulobacter crescentus NA1000 0.27 CCNA_03510 threonine synthase 0.33 CCNA_00562 dihydroorotate dehydrogenase — —
Sinorhizobium meliloti 1021 0.27 SMc00077 threonine synthase 0.39 SMc02245 dihydroorotate dehydrogenase 2 — —
Dinoroseobacter shibae DFL-12 0.26 Dshi_1146 threonine synthase (RefSeq) 0.33 Dshi_0847 Dihydroorotate oxidase (RefSeq) — —
Agrobacterium fabrum C58 0.26 Atu0787 threonine synthase 0.42 Atu0486 dihydroorotate dehydrogenase — —
Azospirillum sp. SherDot2 0.26 MPMX19_00671 Threonine synthase 0.37 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Rhodospirillum rubrum S1H 0.26 Rru_A3233 Threonine synthase (NCBI) 0.38 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) — —
Rhizobium sp. OAE497 0.26 ABIE40_RS04230 threonine synthase 0.39 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Azospirillum brasilense Sp245 0.26 AZOBR_RS10545 threonine synthase 0.38 AZOBR_RS13520 dihydroorotate dehydrogenase — —
Marinobacter adhaerens HP15 0.25 HP15_765 threonine synthase 0.48 HP15_1377 dihydroorotate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.25 TX73_004325 threonine synthase 0.37 TX73_004110 quinone-dependent dihydroorotate dehydrogenase — —
Castellaniella sp019104865 MT123 0.24 ABCV34_RS02300 threonine synthase 0.52 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.24 A4249_RS00020 threonine synthase 0.37 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.24 AMB_RS17140 threonine synthase 0.37 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Sphingomonas koreensis DSMZ 15582 0.23 Ga0059261_1999 threonine synthase 0.39 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) — —
Dechlorosoma suillum PS 0.23 Dsui_2904 threonine synthase 0.55 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.22 GFF3936 Threonine synthase (EC 4.2.3.1) 0.51 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Variovorax sp. OAS795 0.22 ABID97_RS25760 threonine synthase 0.51 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS05865 threonine synthase 0.56 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Paraburkholderia sabiae LMG 24235 0.22 QEN71_RS22400 threonine synthase 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. SCN45 0.21 GFF2800 Threonine synthase (EC 4.2.3.1) 0.51 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Herbaspirillum seropedicae SmR1 0.21 HSERO_RS10470 threonine synthase 0.52 HSERO_RS16155 dihydroorotate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.21 Ac3H11_1505 Threonine synthase (EC 4.2.3.1) 0.52 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Paraburkholderia graminis OAS925 0.21 ABIE53_002027 threonine synthase 0.56 ABIE53_001954 dihydroorotate dehydrogenase — —
Bifidobacterium breve UCC2003 0.21 BBR_RS14070 threonine synthase 0.21 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase low > 34
Cupriavidus basilensis FW507-4G11 0.21 RR42_RS12535 threonine synthase 0.55 RR42_RS07465 dihydroorotate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.21 H281DRAFT_00811 L-threonine synthase 0.54 H281DRAFT_00743 dihydroorotate oxidase A — —
Ralstonia solanacearum GMI1000 0.20 RS_RS06660 threonine synthase 0.54 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Burkholderia phytofirmans PsJN 0.20 BPHYT_RS08960 threonine synthase 0.56 BPHYT_RS08565 dihydroorotate dehydrogenase 0.67 34
Ralstonia solanacearum UW163 0.20 UW163_RS13325 threonine synthase 0.55 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.20 RALBFv3_RS15880 threonine synthase 0.55 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.19 RPSI07_RS17485 threonine synthase 0.54 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —

Not shown: 5 genomes with orthologs for HER17_RS02805 only; 7 genomes with orthologs for HER17_RS12005 only