Conservation of cofitness between HEPCGN_20545 and HEPCGN_04740 in Escherichia coli ECOR38

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_20545 lepA translation elongation factor 4 1.0 HEPCGN_04740 zwf glucose-6-phosphate dehydrogenase 0.81 12
Escherichia coli ECOR27 1.00 NOLOHH_13075 lepA translation elongation factor 4 1.00 NOLOHH_16845 zwf glucose-6-phosphate dehydrogenase low > 75
Escherichia coli ECRC98 1.00 JDDGAC_25065 lepA translation elongation factor 4 1.00 JDDGAC_00910 zwf glucose-6-phosphate dehydrogenase low > 86
Escherichia coli BW25113 1.00 b2569 lepA GTP-binding protein LepA (NCBI) 1.00 b1852 zwf glucose-6-phosphate 1-dehydrogenase (NCBI) — —
Escherichia coli BL21 1.00 ECD_02463 back-translocating elongation factor EF4, GTPase 1.00 ECD_01823 glucose-6-phosphate 1-dehydrogenase — —
Escherichia coli ECRC102 1.00 NIAGMN_19170 lepA translation elongation factor 4 1.00 NIAGMN_01725 zwf glucose-6-phosphate dehydrogenase — —
Escherichia coli ECRC62 1.00 BNILDI_11875 lepA translation elongation factor 4 1.00 BNILDI_15640 zwf glucose-6-phosphate dehydrogenase low > 75
Escherichia coli ECRC100 1.00 OKFHMN_21400 lepA translation elongation factor 4 1.00 OKFHMN_26335 zwf glucose-6-phosphate dehydrogenase low > 80
Escherichia coli ECRC101 1.00 MCAODC_11930 lepA translation elongation factor 4 1.00 MCAODC_19070 zwf glucose-6-phosphate dehydrogenase low > 87
Escherichia coli Nissle 1917 1.00 ECOLIN_RS14540 translation elongation factor 4 1.00 ECOLIN_RS10315 glucose-6-phosphate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01138 Elongation factor 4 1.00 OHPLBJKB_01877 Glucose-6-phosphate 1-dehydrogenase 0.65 4
Escherichia coli ECRC99 1.00 KEDOAH_06820 lepA translation elongation factor 4 1.00 KEDOAH_01770 zwf glucose-6-phosphate dehydrogenase — —
Escherichia fergusonii Becca 1.00 EFB2_01327 Elongation factor 4 1.00 EFB2_02091 Glucose-6-phosphate 1-dehydrogenase low > 86
Klebsiella michiganensis M5al 0.94 BWI76_RS21335 elongation factor 4 0.96 BWI76_RS18105 glucose-6-phosphate dehydrogenase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF2477 Translation elongation factor LepA 0.98 GFF1631 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 78
Enterobacter asburiae PDN3 0.94 EX28DRAFT_0076 elongation factor 4 0.96 EX28DRAFT_0704 glucose-6-phosphate 1-dehydrogenase — —
Enterobacter sp. TBS_079 0.93 MPMX20_03440 Elongation factor 4 0.96 MPMX20_02757 Glucose-6-phosphate 1-dehydrogenase 0.42 13
Dickeya dadantii 3937 0.92 DDA3937_RS15745 elongation factor 4 0.88 DDA3937_RS10135 glucose-6-phosphate dehydrogenase low > 74
Dickeya dianthicola 67-19 0.92 HGI48_RS15830 elongation factor 4 0.87 HGI48_RS10165 glucose-6-phosphate dehydrogenase low > 71
Dickeya dianthicola ME23 0.92 DZA65_RS16910 elongation factor 4 0.87 DZA65_RS10580 glucose-6-phosphate dehydrogenase low > 75
Erwinia tracheiphila SCR3 0.92 LU632_RS15395 lepA translation elongation factor 4 0.90 LU632_RS13360 zwf glucose-6-phosphate dehydrogenase low > 74
Pectobacterium carotovorum WPP14 0.92 HER17_RS05805 translation elongation factor 4 0.88 HER17_RS11780 glucose-6-phosphate dehydrogenase low > 75
Serratia liquefaciens MT49 0.91 IAI46_19560 elongation factor 4 0.88 IAI46_14575 glucose-6-phosphate dehydrogenase — —
Rahnella sp. WP5 0.91 EX31_RS21825 elongation factor 4 0.86 EX31_RS10630 glucose-6-phosphate dehydrogenase — —
Pantoea sp. MT58 0.89 IAI47_04870 elongation factor 4 0.91 IAI47_08495 glucose-6-phosphate dehydrogenase — —
Vibrio cholerae E7946 ATCC 55056 0.85 CSW01_12465 elongation factor 4 0.38 CSW01_18625 glucose-6-phosphate dehydrogenase low > 62
Shewanella sp. ANA-3 0.83 Shewana3_3028 GTP-binding protein LepA (RefSeq) 0.66 Shewana3_2151 glucose-6-phosphate 1-dehydrogenase (RefSeq) — —
Shewanella oneidensis MR-1 0.83 SO1346 lepA GTP-binding protein LepA (NCBI ptt file) 0.66 SO2489 zwf glucose-6-phosphate 1-dehydrogenase (NCBI ptt file) 0.24 57
Shewanella loihica PV-4 0.82 Shew_1052 GTP-binding protein LepA (RefSeq) 0.66 Shew_2048 glucose-6-phosphate 1-dehydrogenase (RefSeq) — —
Alteromonas macleodii MIT1002 0.81 MIT1002_02715 Elongation factor 4 0.61 MIT1002_02407 Glucose-6-phosphate 1-dehydrogenase low > 70
Shewanella amazonensis SB2B 0.80 Sama_0878 GTP-binding protein LepA (RefSeq) 0.65 Sama_1812 glucose-6-phosphate 1-dehydrogenase (RefSeq) — —
Pseudomonas sp. S08-1 0.76 OH686_20065 elongation factor 4 0.53 OH686_02435 glucose-6-phosphate dehydrogenase low > 80
Pseudomonas sp. RS175 0.76 PFR28_03525 Elongation factor 4 0.52 PFR28_00573 Glucose-6-phosphate 1-dehydrogenase — —
Pseudomonas putida KT2440 0.76 PP_1431 Elongation factor 4 0.52 PP_1022 glucose 6-phosphate-1-dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.75 PFLU_RS05250 elongation factor 4 0.54 PFLU_RS23725 glucose-6-phosphate dehydrogenase 0.25 80
Pseudomonas fluorescens GW456-L13 0.75 PfGW456L13_4842 Translation elongation factor LepA 0.54 PfGW456L13_1901 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 87
Pseudomonas fluorescens SBW25 0.75 PFLU_RS05250 elongation factor 4 0.54 PFLU_RS23725 glucose-6-phosphate dehydrogenase low > 109
Pseudomonas fluorescens FW300-N2E2 0.75 Pf6N2E2_5423 Translation elongation factor LepA 0.53 Pf6N2E2_2885 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) — —
Pseudomonas fluorescens FW300-N2C3 0.75 AO356_17485 elongation factor 4 0.53 AO356_05160 glucose-6-phosphate dehydrogenase low > 104
Pseudomonas simiae WCS417 0.75 PS417_05180 elongation factor 4 0.54 PS417_22110 glucose-6-phosphate dehydrogenase — —
Pseudomonas stutzeri RCH2 0.75 Psest_3095 GTP-binding protein LepA 0.53 Psest_0852 glucose-6-phosphate 1-dehydrogenase — —
Pseudomonas fluorescens FW300-N2E3 0.75 AO353_04520 elongation factor 4 0.54 AO353_03360 glucose-6-phosphate dehydrogenase low > 101
Pseudomonas fluorescens FW300-N1B4 0.75 Pf1N1B4_895 Translation elongation factor LepA 0.53 Pf1N1B4_589 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.74 Psyr_3954 GTP-binding protein LepA 0.53 Psyr_1120 glucose-6-phosphate 1-dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a 0.74 Psyr_3954 GTP-binding protein LepA 0.53 Psyr_1120 glucose-6-phosphate 1-dehydrogenase low > 86
Marinobacter adhaerens HP15 0.74 HP15_781 GTP-binding protein LepA 0.55 HP15_2179 glucose-6-phosphate 1-dehydrogenase low > 73
Herbaspirillum seropedicae SmR1 0.73 HSERO_RS09650 elongation factor 4 0.45 HSERO_RS05510 glucose-6-phosphate 1-dehydrogenase — —
Burkholderia phytofirmans PsJN 0.73 BPHYT_RS14380 elongation factor 4 0.43 BPHYT_RS05020 glucose-6-phosphate 1-dehydrogenase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.72 H281DRAFT_04360 GTP-binding protein LepA 0.43 H281DRAFT_00165 glucose-6-phosphate 1-dehydrogenase low > 103
Paraburkholderia graminis OAS925 0.72 ABIE53_003038 GTP-binding protein LepA 0.42 ABIE53_006464 glucose-6-phosphate 1-dehydrogenase low > 113
Rhodanobacter sp. FW510-T8 0.71 OKGIIK_07885 Elongation factor 4 0.47 OKGIIK_14360 zwf glucose-6-phosphate dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.71 RR42_RS14055 elongation factor 4 0.44 RR42_RS37405 glucose-6-phosphate dehydrogenase low > 128
Rhodanobacter denitrificans FW104-10B01 0.70 LRK54_RS16955 translation elongation factor 4 0.47 LRK54_RS07870 glucose-6-phosphate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.70 LRK55_RS16670 translation elongation factor 4 0.47 LRK55_RS07600 glucose-6-phosphate dehydrogenase — —
Paraburkholderia sabiae LMG 24235 0.70 QEN71_RS04600 translation elongation factor 4 0.43 QEN71_RS03330 glucose-6-phosphate dehydrogenase low > 153
Dyella japonica UNC79MFTsu3.2 0.70 ABZR86_RS07165 translation elongation factor 4 0.49 ABZR86_RS14700 glucose-6-phosphate dehydrogenase low > 74
Ralstonia solanacearum PSI07 0.70 RPSI07_RS18990 elongation factor 4 0.45 RPSI07_RS07315 glucose-6-phosphate dehydrogenase low > 81
Lysobacter sp. OAE881 0.70 ABIE51_RS13875 translation elongation factor 4 0.46 ABIE51_RS01620 glucose-6-phosphate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.69 Xcc-8004.3676.1 Translation elongation factor LepA 0.34 Xcc-8004.2450.1 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 74
Ralstonia sp. UNC404CL21Col 0.69 ABZR87_RS10190 translation elongation factor 4 0.44 ABZR87_RS22915 glucose-6-phosphate dehydrogenase low > 80
Variovorax sp. SCN45 0.68 GFF3867 Translation elongation factor LepA 0.40 GFF5261 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 127
Variovorax sp. OAS795 0.68 ABID97_RS08350 translation elongation factor 4 0.40 ABID97_RS07065 glucose-6-phosphate dehydrogenase low > 91
Acidovorax sp. GW101-3H11 0.68 Ac3H11_1569 Translation elongation factor LepA 0.40 Ac3H11_2076 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.68 GFF3343 Translation elongation factor LepA 0.44 GFF5493 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 90
Ralstonia solanacearum UW163 0.68 UW163_RS11935 elongation factor 4 0.45 UW163_RS17130 glucose-6-phosphate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.68 RALBFv3_RS14470 elongation factor 4 0.45 RALBFv3_RS16390 glucose-6-phosphate dehydrogenase low > 76
Ralstonia solanacearum GMI1000 0.68 RS_RS05250 elongation factor 4 0.45 RS_RS24615 glucose-6-phosphate dehydrogenase — —
Azospirillum sp. SherDot2 0.62 MPMX19_00092 Elongation factor 4 0.46 MPMX19_05119 Glucose-6-phosphate 1-dehydrogenase — —
Agrobacterium fabrum C58 0.61 Atu0241 GTP-binding protein LepA 0.47 Atu0600 glucose-6-phosphate 1-dehydrogenase — —
Caulobacter crescentus NA1000 0.60 CCNA_01086 GTP-binding protein lepA 0.43 CCNA_02136 glucose-6-phosphate 1-dehydrogenase — —
Caulobacter crescentus NA1000 Δfur 0.60 CCNA_01086 GTP-binding protein lepA 0.43 CCNA_02136 glucose-6-phosphate 1-dehydrogenase low > 67
Sinorhizobium meliloti 1021 0.60 SMc00349 GTP-binding protein LepA 0.46 SMc03070 glucose-6-phosphate 1-dehydrogenase low > 103
Rhizobium sp. OAE497 0.60 ABIE40_RS01055 translation elongation factor 4 0.46 ABIE40_RS03200 glucose-6-phosphate dehydrogenase — —
Sphingomonas koreensis DSMZ 15582 0.59 Ga0059261_3979 elongation factor 4 0.43 Ga0059261_0352 glucose-6-phosphate 1-dehydrogenase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.59 A4249_RS10390 translation elongation factor 4 0.44 A4249_RS10725 glucose-6-phosphate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.59 TX73_001825 translation elongation factor 4 0.33 TX73_018845 glucose-6-phosphate dehydrogenase low > 86
Bosea sp. OAE506 0.59 ABIE41_RS03260 translation elongation factor 4 0.43 ABIE41_RS23515 glucose-6-phosphate dehydrogenase low > 77
Phaeobacter inhibens DSM 17395 0.58 PGA1_c24090 GTP-binding protein LepA 0.39 PGA1_c27990 glucose-6-phosphate 1-dehydrogenase — —
Synechococcus elongatus PCC 7942 0.58 Synpcc7942_0479 lepA GTP-binding protein LepA 0.39 Synpcc7942_2334 zwf glucose-6-phosphate 1-dehydrogenase low > 38
Dinoroseobacter shibae DFL-12 0.58 Dshi_0809 GTP-binding protein LepA (RefSeq) 0.42 Dshi_1684 glucose-6-phosphate 1-dehydrogenase (RefSeq) — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.57 Echvi_4645 GTP-binding protein LepA 0.39 Echvi_2862 glucose-6-phosphate 1-dehydrogenase low > 79
Pedobacter sp. GW460-11-11-14-LB5 0.56 CA265_RS08955 elongation factor 4 0.38 CA265_RS09810 glucose-6-phosphate dehydrogenase low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.56 ABZR88_RS09405 translation elongation factor 4 0.38 ABZR88_RS02975 glucose-6-phosphate dehydrogenase low > 71
Parabacteroides merdae CL09T00C40 0.56 HMPREF1078_RS09970 translation elongation factor 4 0.32 HMPREF1078_RS08635 glucose-6-phosphate dehydrogenase low > 61
Phocaeicola dorei CL03T12C01 0.56 ABI39_RS20175 translation elongation factor 4 0.34 ABI39_RS14355 glucose-6-phosphate dehydrogenase low > 72
Phocaeicola vulgatus CL09T03C04 0.56 HMPREF1058_RS06410 elongation factor 4 0.33 HMPREF1058_RS18030 glucose-6-phosphate dehydrogenase low > 67
Bacteroides stercoris CC31F 0.55 HMPREF1181_RS16590 elongation factor 4 0.37 HMPREF1181_RS12520 glucose-6-phosphate dehydrogenase low > 56
Bifidobacterium breve UCC2003 0.55 BBR_RS15230 elongation factor 4 0.38 BBR_RS11480 glucose-6-phosphate dehydrogenase — —
Bacteroides ovatus ATCC 8483 0.54 BACOVA_02258 GTP-binding protein LepA 0.37 BACOVA_00508 glucose-6-phosphate dehydrogenase low > 94
Bacteroides thetaiotaomicron VPI-5482 0.53 BT0632 GTP-binding protein, membrane GTPase lepA (NCBI ptt file) 0.36 BT1221 glucose-6-phosphate 1-dehydrogenase (NCBI ptt file) — —
Mycobacterium tuberculosis H37Rv 0.53 Rv2404c Probable GTP-binding protein LepA (GTP-binding elongation factor) 0.37 Rv1447c Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) low > 58

Not shown: 11 genomes with orthologs for HEPCGN_20545 only; 0 genomes with orthologs for HEPCGN_04740 only