Conservation of cofitness between PGA1_c12150 and PGA1_c35480 in Phaeobacter inhibens DSM 17395

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Phaeobacter inhibens DSM 17395 1.0 PGA1_c12150 dihydroorotate dehydrogenase PyrD 1.0 PGA1_c35480 glycerol-3-phosphate dehydrogenase GpsA 0.90 7
Dinoroseobacter shibae DFL-12 0.70 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.50 Dshi_3414 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein (RefSeq) 0.77 20
Azospirillum sp. SherDot2 0.47 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) 0.36 MPMX19_02123 Glycerol-3-phosphate dehydrogenase [NAD(P)+] — —
Sinorhizobium meliloti 1021 0.47 SMc02245 dihydroorotate dehydrogenase 2 0.38 SMc03229 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 0.74 82
Agrobacterium fabrum C58 0.46 Atu0486 dihydroorotate dehydrogenase 0.37 Atu2650 glycerol-3-phosphate dehydrogenase 0.83 28
Azospirillum brasilense Sp245 0.44 AZOBR_RS13520 dihydroorotate dehydrogenase 0.36 AZOBR_RS00325 glycerol-3-phosphate dehydrogenase 0.58 31
Brevundimonas sp. GW460-12-10-14-LB2 0.44 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase 0.35 A4249_RS15450 NAD(P)-dependent glycerol-3-phosphate dehydrogenase — —
Rhizobium sp. OAE497 0.44 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase 0.38 ABIE40_RS18055 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Caulobacter crescentus NA1000 Δfur 0.42 CCNA_00562 dihydroorotate dehydrogenase 0.34 CCNA_00068 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Caulobacter crescentus NA1000 0.42 CCNA_00562 dihydroorotate dehydrogenase 0.34 CCNA_00068 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.41 TX73_004110 quinone-dependent dihydroorotate dehydrogenase 0.36 TX73_001320 NAD(P)-dependent glycerol-3-phosphate dehydrogenase — —
Rhodospirillum rubrum S1H 0.41 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.37 Rru_A3571 Glycerol-3-phosphate dehydrogenase (NAD(P)+) (NCBI) low > 58
Bosea sp. OAE506 0.40 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.34 ABIE41_RS05655 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase low > 77
Pseudomonas stutzeri RCH2 0.38 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.30 Psest_2471 Glycerol-3-phosphate dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase 0.34 OKGIIK_13015 gpsA glycerol-3-phosphate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.37 CA265_RS14005 dihydroorotate dehydrogenase (quinone) 0.18 CA265_RS16375 glycerol-3-phosphate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.37 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.33 Ac3H11_3860 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) — —
Sphingomonas koreensis DSMZ 15582 0.37 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) 0.40 Ga0059261_2234 Glycerol-3-phosphate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase 0.31 LRK54_RS10860 NAD(P)-dependent glycerol-3-phosphate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.37 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase 0.31 LRK55_RS10550 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.37 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 0.22 Echvi_0322 Glycerol-3-phosphate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.32 PFLU_RS09055 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.36 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.32 PFLU_RS09055 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.36 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase 0.17 ABZR88_RS01515 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.36 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.33 PfGW456L13_2046 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) — —
Castellaniella sp019104865 MT123 0.36 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase 0.34 ABCV34_RS14250 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.36 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase 0.32 ABZR86_RS13250 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Variovorax sp. SCN45 0.36 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) 0.32 GFF2573 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) — —
Pseudomonas sp. S08-1 0.36 OH686_03120 dihydroorotate dehydrogenase (fumarate) 0.28 OH686_00475 Glycerol-3-phosphate dehydrogenase [NAD(P)+] — —
Pseudomonas simiae WCS417 0.36 PS417_20935 dihydroorotate dehydrogenase 0.32 PS417_09000 glycerol-3-phosphate dehydrogenase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.34 GFF1222 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) low > 90
Shewanella oneidensis MR-1 0.36 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.31 SO0053 gpsA glycerol-3-phosphate dehydrogenase (NAD(P)+) (NCBI ptt file) — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.32 AO353_01735 glycerol-3-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.36 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.29 Pf1N1B4_3518 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) — —
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.33 Pf6N2E2_5875 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) — —
Shewanella sp. ANA-3 0.36 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.30 Shewana3_0054 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase (RefSeq) — —
Ralstonia solanacearum UW163 0.36 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase 0.31 UW163_RS02660 glycerol-3-phosphate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.36 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase 0.31 RALBFv3_RS10920 glycerol-3-phosphate dehydrogenase — —
Acinetobacter radioresistens SK82 0.36 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.30 MPMX26_01116 Glycerol-3-phosphate dehydrogenase [NAD(P)+] — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase 0.30 ABZR87_RS06770 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Variovorax sp. OAS795 0.35 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase 0.34 ABID97_RS07405 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N2C3 0.35 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.33 AO356_19795 glycerol-3-phosphate dehydrogenase — —
Pseudomonas sp. RS175 0.35 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.32 PFR28_03076 Glycerol-3-phosphate dehydrogenase [NAD(P)+] — —
Alteromonas macleodii MIT1002 0.35 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.34 MIT1002_00485 Glycerol-3-phosphate dehydrogenase [NAD(P)+] low > 70
Pontibacter actiniarum KMM 6156, DSM 19842 0.35 CA264_00865 dihydroorotate dehydrogenase (quinone) 0.16 CA264_05630 glycerol-3-phosphate dehydrogenase low > 74
Paraburkholderia graminis OAS925 0.35 ABIE53_001954 dihydroorotate dehydrogenase 0.27 ABIE53_000667 glycerol-3-phosphate dehydrogenase (NAD(P)+) — —
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_2106 dihydroorotate oxidase A 0.32 Psyr_2022 Glycerol-3-phosphate dehydrogenase (NAD(P)+) — —
Ralstonia solanacearum PSI07 0.35 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase 0.29 RPSI07_RS22390 glycerol-3-phosphate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_2106 dihydroorotate oxidase A 0.32 Psyr_2022 Glycerol-3-phosphate dehydrogenase (NAD(P)+) — —
Dechlorosoma suillum PS 0.35 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 0.31 Dsui_1277 glycerol-3-phosphate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.35 RS_RS08160 dihydroorotate dehydrogenase (quinone) 0.30 RS_RS01760 glycerol-3-phosphate dehydrogenase (NAD(P)(+)) — —
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS08565 dihydroorotate dehydrogenase 0.26 BPHYT_RS02610 glycerol-3-phosphate dehydrogenase [NAD(P)+] 0.62 35
Paraburkholderia sabiae LMG 24235 0.34 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase 0.27 QEN71_RS01465 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Pseudomonas putida KT2440 0.34 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.34 PP_4169 Glycerol-3-phosphate dehydrogenase [NAD(P)+] — —
Cupriavidus basilensis FW507-4G11 0.34 RR42_RS07465 dihydroorotate dehydrogenase 0.30 RR42_RS01845 glycerol-3-phosphate dehydrogenase — —
Dickeya dadantii 3937 0.34 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.29 DDA3937_RS20405 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.34 HSERO_RS16155 dihydroorotate dehydrogenase 0.34 HSERO_RS00795 glycerol-3-phosphate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.34 H281DRAFT_00743 dihydroorotate oxidase A 0.29 H281DRAFT_02000 glycerol-3-phosphate dehydrogenase (NAD(P)+) — —
Xanthomonas campestris pv. campestris strain 8004 0.34 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.31 Xcc-8004.271.1 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) — —
Pantoea sp. MT58 0.33 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.31 IAI47_00740 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Klebsiella michiganensis M5al 0.33 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.30 BWI76_RS27210 glycerol-3-phosphate dehydrogenase — —
Vibrio cholerae E7946 ATCC 55056 0.33 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.32 CSW01_13405 glycerol-3-phosphate dehydrogenase (NAD(P)(+)) — —
Pectobacterium carotovorum WPP14 0.33 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.29 HER17_RS20735 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase low > 75
Dickeya dianthicola ME23 0.33 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.29 DZA65_RS00850 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Shewanella loihica PV-4 0.33 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.32 Shew_3803 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase (RefSeq) — —
Escherichia coli Nissle 1917 0.33 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase 0.30 ECOLIN_RS20595 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Escherichia fergusonii Becca 0.33 EFB2_03126 Dihydroorotate dehydrogenase (quinone) 0.30 EFB2_00202 Glycerol-3-phosphate dehydrogenase [NAD(P)+] — —
Enterobacter sp. TBS_079 0.33 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.29 MPMX20_00125 Glycerol-3-phosphate dehydrogenase [NAD(P)+] — —
Shewanella amazonensis SB2B 0.33 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.31 Sama_0063 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase (RefSeq) — —
Kangiella aquimarina DSM 16071 0.33 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) 0.34 B158DRAFT_0712 Glycerol-3-phosphate dehydrogenase — —
Escherichia coli ECOR38 0.33 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 HEPCGN_14595 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Enterobacter asburiae PDN3 0.33 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) 0.29 EX28DRAFT_3859 Glycerol-3-phosphate dehydrogenase — —
Dickeya dianthicola 67-19 0.33 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.29 HGI48_RS00795 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase low > 71
Escherichia coli ECRC101 0.33 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 MCAODC_06265 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Escherichia coli BW25113 0.33 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.30 b3608 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase (NCBI) — —
Escherichia coli ECRC101 0.33 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 OKFHMN_15755 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.33 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 0.30 OHPLBJKB_00091 Glycerol-3-phosphate dehydrogenase [NAD(P)+] — —
Escherichia coli ECRC62 0.33 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 BNILDI_03880 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Escherichia coli ECOR27 0.33 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 NOLOHH_07635 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Escherichia coli BL21 0.33 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.30 ECD_03466 glycerol-3-phosphate dehydrogenase (NAD+) — —
Erwinia tracheiphila SCR3 0.33 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.31 LU632_RS21875 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 0.73 51
Escherichia coli ECRC99 0.33 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 KEDOAH_12395 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Escherichia coli ECRC98 0.33 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 JDDGAC_19380 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Lysobacter sp. OAE881 0.33 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase 0.32 ABIE51_RS00495 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Escherichia coli ECRC102 0.33 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 NIAGMN_13515 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase — —
Rahnella sp. WP5 0.32 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.31 EX31_RS14340 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase low > 89
Serratia liquefaciens MT49 0.32 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.31 IAI46_24690 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase low > 86
Mycobacterium tuberculosis H37Rv 0.32 Rv2139 Probable dihydroorotate dehydrogenase PyrD 0.33 Rv2982c Probable glycerol-3-phosphate dehydrogenase [NAD(P)+] GpdA2 (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.31 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.30 GFF402 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) — —
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_0290 pyrD dihydroorotate dehydrogenase 2 0.24 Synpcc7942_2522 Glycerol-3-phosphate dehydrogenase (NAD(P)+) — —
Bifidobacterium breve UCC2003 0.21 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase 0.25 BBR_RS12080 NAD(P)-dependent glycerol-3-phosphate dehydrogenase — —

Not shown: 1 genomes with orthologs for PGA1_c12150 only; 9 genomes with orthologs for PGA1_c35480 only