| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Phaeobacter inhibens DSM 17395 | 1.0 | PGA1_c12150 | | dihydroorotate dehydrogenase PyrD | 1.0 | PGA1_c29780 | | 3-isopropylmalate dehydratase large subunit | 0.88 | 12 |
| Dinoroseobacter shibae DFL-12 | 0.70 | Dshi_0847 | | Dihydroorotate oxidase (RefSeq) | 0.85 | Dshi_0085 | | 3-isopropylmalate dehydratase, large subunit (RefSeq) | 0.77 | 21 |
| Azospirillum sp. SherDot2 | 0.47 | MPMX19_02083 | | Dihydroorotate dehydrogenase (quinone) | 0.75 | MPMX19_01998 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Sinorhizobium meliloti 1021 | 0.47 | SMc02245 | | dihydroorotate dehydrogenase 2 | 0.73 | SMc03823 | | isopropylmalate isomerase large subunit | 0.86 | 37 |
| Agrobacterium fabrum C58 | 0.46 | Atu0486 | | dihydroorotate dehydrogenase | 0.72 | Atu2709 | | 3-isopropylmalate dehydratase, large subunit | 0.87 | 15 |
| Magnetospirillum magneticum AMB-1 | 0.45 | AMB_RS19685 | | quinone-dependent dihydroorotate dehydrogenase | 0.71 | AMB_RS20560 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Azospirillum brasilense Sp245 | 0.44 | AZOBR_RS13520 | | dihydroorotate dehydrogenase | 0.73 | AZOBR_RS03545 | | isopropylmalate isomerase | 0.68 | 6 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.44 | A4249_RS00280 | | quinone-dependent dihydroorotate dehydrogenase | 0.52 | A4249_RS10005 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Rhizobium sp. OAE497 | 0.44 | ABIE40_RS02420 | | quinone-dependent dihydroorotate dehydrogenase | 0.71 | ABIE40_RS18380 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.42 | CCNA_00562 | | dihydroorotate dehydrogenase | 0.65 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | low | > 67 |
| Caulobacter crescentus NA1000 | 0.42 | CCNA_00562 | | dihydroorotate dehydrogenase | 0.65 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | 0.88 | 16 |
| Rhodospirillum rubrum S1H | 0.41 | Rru_A0514 | | Dihydroorotate dehydrogenase 2 (NCBI) | 0.70 | Rru_A1189 | | 3-isopropylmalate dehydratase large subunit region (NCBI) | 0.86 | 11 |
| Rhodopseudomonas palustris CGA009 | 0.41 | TX73_004110 | | quinone-dependent dihydroorotate dehydrogenase | 0.69 | TX73_001245 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Bosea sp. OAE506 | 0.40 | ABIE41_RS24065 | | quinone-dependent dihydroorotate dehydrogenase | 0.72 | ABIE41_RS11660 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas stutzeri RCH2 | 0.38 | Psest_1947 | | dihydroorotate dehydrogenase, subfamily 2 | 0.62 | Psest_2591 | | 3-isopropylmalate dehydratase, large subunit | 0.44 | 20 |
| Rhodanobacter sp. FW510-T8 | 0.37 | OKGIIK_09010 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.49 | OKGIIK_13585 | leuC | 3-isopropylmalate dehydratase large subunit | — | — |
| Acidovorax sp. GW101-3H11 | 0.37 | Ac3H11_4100 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.59 | Ac3H11_1525 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.37 | CA265_RS14005 | | dihydroorotate dehydrogenase (quinone) | 0.53 | CA265_RS15830 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.37 | Ga0059261_1468 | | dihydroorotate oxidase A (EC 1.3.3.1) | 0.64 | Ga0059261_4223 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.37 | LRK54_RS15985 | | quinone-dependent dihydroorotate dehydrogenase | 0.56 | LRK54_RS07375 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.37 | Echvi_1806 | | dihydroorotate dehydrogenase, subfamily 2 | 0.54 | Echvi_2059 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Rhodanobacter denitrificans MT42 | 0.37 | LRK55_RS15740 | | quinone-dependent dihydroorotate dehydrogenase | 0.56 | LRK55_RS07105 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens SBW25 | 0.36 | PFLU_RS22550 | | quinone-dependent dihydroorotate dehydrogenase | 0.62 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.36 | PFLU_RS22550 | | quinone-dependent dihydroorotate dehydrogenase | 0.62 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.36 | ABZR88_RS12040 | | quinone-dependent dihydroorotate dehydrogenase | 0.54 | ABZR88_RS11595 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.36 | PfGW456L13_4095 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.63 | PfGW456L13_3948 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.36 | ABZR86_RS07450 | | quinone-dependent dihydroorotate dehydrogenase | 0.50 | ABZR86_RS15960 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Castellaniella sp019104865 MT123 | 0.36 | ABCV34_RS07790 | | quinone-dependent dihydroorotate dehydrogenase | 0.62 | ABCV34_RS04290 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Variovorax sp. SCN45 | 0.36 | GFF960 | | Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) | 0.61 | GFF3890 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Pseudomonas sp. S08-1 | 0.36 | OH686_03120 | | dihydroorotate dehydrogenase (fumarate) | 0.64 | OH686_04480 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas simiae WCS417 | 0.36 | PS417_20935 | | dihydroorotate dehydrogenase | 0.62 | PS417_18600 | | isopropylmalate isomerase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.36 | AO353_00780 | | dihydroorotate dehydrogenase (quinone) | 0.63 | AO353_20620 | | isopropylmalate isomerase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.36 | GFF4211 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.61 | GFF3363 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | low | > 90 |
| Shewanella oneidensis MR-1 | 0.36 | SO2592 | pyrD | dihydroorotate dehydrogenase (NCBI ptt file) | 0.59 | SO4234 | leuC | 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) | 0.84 | 42 |
| Pseudomonas fluorescens FW300-N1B4 | 0.36 | Pf1N1B4_3842 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.63 | Pf1N1B4_15 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.36 | Pf6N2E2_2347 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.64 | Pf6N2E2_63 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Shewanella sp. ANA-3 | 0.36 | Shewana3_1786 | | dihydroorotate dehydrogenase 2 (RefSeq) | 0.59 | Shewana3_3759 | | isopropylmalate isomerase large subunit (RefSeq) | 0.86 | 28 |
| Ralstonia solanacearum IBSBF1503 | 0.36 | RALBFv3_RS01570 | | quinone-dependent dihydroorotate dehydrogenase | 0.62 | RALBFv3_RS02620 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia solanacearum UW163 | 0.36 | UW163_RS14880 | | quinone-dependent dihydroorotate dehydrogenase | 0.62 | UW163_RS11105 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Acinetobacter radioresistens SK82 | 0.36 | MPMX26_01120 | | Dihydroorotate dehydrogenase (quinone) | 0.62 | MPMX26_00345 | | 3-isopropylmalate dehydratase large subunit | low | > 36 |
| Variovorax sp. OAS795 | 0.35 | ABID97_RS14065 | | quinone-dependent dihydroorotate dehydrogenase | 0.62 | ABID97_RS08465 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.35 | AO356_02610 | | dihydroorotate dehydrogenase (quinone) | 0.64 | AO356_21400 | | isopropylmalate isomerase | — | — |
| Pseudomonas sp. RS175 | 0.35 | PFR28_01054 | | Dihydroorotate dehydrogenase (quinone) | 0.63 | PFR28_02824 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia sp. UNC404CL21Col | 0.35 | ABZR87_RS13360 | | quinone-dependent dihydroorotate dehydrogenase | 0.64 | ABZR87_RS14540 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Alteromonas macleodii MIT1002 | 0.35 | MIT1002_02035 | | Dihydroorotate dehydrogenase (quinone) | 0.59 | MIT1002_00947 | | 3-isopropylmalate dehydratase large subunit | low | > 70 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.35 | CA264_00865 | | dihydroorotate dehydrogenase (quinone) | 0.52 | CA264_09435 | | 3-isopropylmalate dehydratase large subunit | low | > 74 |
| Paraburkholderia graminis OAS925 | 0.35 | ABIE53_001954 | | dihydroorotate dehydrogenase | 0.63 | ABIE53_004801 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.35 | Psyr_2106 | | dihydroorotate oxidase A | 0.63 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Ralstonia solanacearum PSI07 | 0.35 | RPSI07_RS15920 | | quinone-dependent dihydroorotate dehydrogenase | 0.63 | RPSI07_RS14695 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.35 | Psyr_2106 | | dihydroorotate oxidase A | 0.63 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Ralstonia solanacearum GMI1000 | 0.35 | RS_RS08160 | | dihydroorotate dehydrogenase (quinone) | 0.62 | RS_RS10000 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Dechlorosoma suillum PS | 0.35 | Dsui_2978 | | dihydroorotate dehydrogenase, subfamily 2 | 0.60 | Dsui_3201 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Burkholderia phytofirmans PsJN | 0.35 | BPHYT_RS08565 | | dihydroorotate dehydrogenase | 0.62 | BPHYT_RS33915 | | isopropylmalate isomerase | 0.64 | 27 |
| Paraburkholderia sabiae LMG 24235 | 0.34 | QEN71_RS22765 | | quinone-dependent dihydroorotate dehydrogenase | 0.62 | QEN71_RS17605 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas putida KT2440 | 0.34 | PP_2095 | | Dihydroorotate dehydrogenase (quinone) | 0.62 | PP_1985 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.34 | RR42_RS07465 | | dihydroorotate dehydrogenase | 0.64 | RR42_RS14400 | | isopropylmalate isomerase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.34 | HSERO_RS16155 | | dihydroorotate dehydrogenase | 0.62 | HSERO_RS16515 | | isopropylmalate isomerase | — | — |
| Dickeya dadantii 3937 | 0.34 | DDA3937_RS12855 | | quinone-dependent dihydroorotate dehydrogenase | 0.64 | DDA3937_RS18125 | | 3-isopropylmalate dehydratase large subunit | 0.59 | 51 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.34 | Xcc-8004.3032.1 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.63 | Xcc-8004.1049.1 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.34 | H281DRAFT_00743 | | dihydroorotate oxidase A | 0.63 | H281DRAFT_06075 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Klebsiella michiganensis M5al | 0.33 | BWI76_RS09910 | | dihydroorotate dehydrogenase (quinone) | 0.64 | BWI76_RS04670 | | 3-isopropylmalate dehydratase large subunit | 0.61 | 32 |
| Vibrio cholerae E7946 ATCC 55056 | 0.33 | CSW01_07490 | | dihydroorotate dehydrogenase (quinone) | 0.60 | CSW01_12605 | | 3-isopropylmalate dehydratase large subunit | low | > 62 |
| Pantoea sp. MT58 | 0.33 | IAI47_12705 | | quinone-dependent dihydroorotate dehydrogenase | 0.63 | IAI47_16010 | | 3-isopropylmalate dehydratase large subunit | 0.78 | 39 |
| Dickeya dianthicola ME23 | 0.33 | DZA65_RS13390 | | quinone-dependent dihydroorotate dehydrogenase | 0.64 | DZA65_RS19210 | | 3-isopropylmalate dehydratase large subunit | 0.84 | 12 |
| Pectobacterium carotovorum WPP14 | 0.33 | HER17_RS12005 | | quinone-dependent dihydroorotate dehydrogenase | 0.63 | HER17_RS03075 | | 3-isopropylmalate dehydratase large subunit | 0.96 | 19 |
| Shewanella loihica PV-4 | 0.33 | Shew_1810 | | dihydroorotate dehydrogenase 2 (RefSeq) | 0.59 | Shew_3470 | | isopropylmalate isomerase large subunit (RefSeq) | 0.76 | 25 |
| Escherichia coli Nissle 1917 | 0.33 | ECOLIN_RS04965 | | quinone-dependent dihydroorotate dehydrogenase | 0.64 | ECOLIN_RS00390 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Escherichia fergusonii Becca | 0.33 | EFB2_03126 | | Dihydroorotate dehydrogenase (quinone) | 0.64 | EFB2_03973 | | 3-isopropylmalate dehydratase large subunit | low | > 86 |
| Shewanella amazonensis SB2B | 0.33 | Sama_1593 | | dihydroorotate dehydrogenase 2 (RefSeq) | 0.58 | Sama_0337 | | isopropylmalate isomerase large subunit (RefSeq) | low | > 62 |
| Enterobacter sp. TBS_079 | 0.33 | MPMX20_01596 | | Dihydroorotate dehydrogenase (quinone) | 0.63 | MPMX20_00767 | | 3-isopropylmalate dehydratase large subunit 1 | 0.75 | 53 |
| Escherichia coli ECOR38 | 0.33 | HEPCGN_23225 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.64 | HEPCGN_08705 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | low | > 85 |
| Kangiella aquimarina DSM 16071 | 0.33 | B158DRAFT_2228 | | dihydroorotate oxidase A (EC 1.3.3.1) | 0.64 | B158DRAFT_1319 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Enterobacter asburiae PDN3 | 0.33 | EX28DRAFT_1998 | | dihydroorotate oxidase A (EC 1.3.3.1) | 0.64 | EX28DRAFT_3668 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Dickeya dianthicola 67-19 | 0.33 | HGI48_RS12925 | | quinone-dependent dihydroorotate dehydrogenase | 0.64 | HGI48_RS18065 | | 3-isopropylmalate dehydratase large subunit | 0.77 | 14 |
| Escherichia coli ECRC102 | 0.33 | NIAGMN_03015 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.64 | NIAGMN_08575 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC98 | 0.33 | JDDGAC_08905 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.64 | JDDGAC_14320 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli BL21 | 0.33 | ECD_00949 | | dihydro-orotate oxidase, FMN-linked | 0.64 | ECD_00074 | | 3-isopropylmalate dehydratase large subunit | low | > 60 |
| Erwinia tracheiphila SCR3 | 0.33 | LU632_RS09955 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.59 | LU632_RS02870 | leuC | 3-isopropylmalate dehydratase large subunit | 0.81 | 22 |
| Lysobacter sp. OAE881 | 0.33 | ABIE51_RS13725 | | quinone-dependent dihydroorotate dehydrogenase | 0.50 | ABIE51_RS17575 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Escherichia coli ECRC99 | 0.33 | KEDOAH_22440 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.64 | KEDOAH_17430 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC101 | 0.33 | MCAODC_24685 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.64 | MCAODC_01240 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.33 | OHPLBJKB_02721 | | Dihydroorotate dehydrogenase (quinone) | 0.64 | OHPLBJKB_03585 | | 3-isopropylmalate dehydratase large subunit | low | > 73 |
| Escherichia coli ECRC62 | 0.33 | BNILDI_20015 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.64 | BNILDI_08540 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC101 | 0.33 | OKFHMN_05295 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.64 | OKFHMN_10725 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli BW25113 | 0.33 | b0945 | pyrD | dihydroorotate dehydrogenase (NCBI) | 0.64 | b0072 | leuC | isopropylmalate isomerase large subunit (NCBI) | 0.76 | 54 |
| Escherichia coli ECOR27 | 0.33 | NOLOHH_21850 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.64 | NOLOHH_03070 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.59 | 25 |
| Serratia liquefaciens MT49 | 0.32 | IAI46_08805 | | quinone-dependent dihydroorotate dehydrogenase | 0.62 | IAI46_03345 | | 3-isopropylmalate dehydratase large subunit | 0.72 | 42 |
| Rahnella sp. WP5 | 0.32 | EX31_RS18095 | | quinone-dependent dihydroorotate dehydrogenase | 0.64 | EX31_RS03690 | | 3-isopropylmalate dehydratase large subunit | 0.94 | 5 |
| Mycobacterium tuberculosis H37Rv | 0.32 | Rv2139 | | Probable dihydroorotate dehydrogenase PyrD | 0.61 | Rv2988c | | Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.31 | GFF3236 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.64 | GFF166 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | low | > 78 |
| Synechococcus elongatus PCC 7942 | 0.30 | Synpcc7942_0290 | pyrD | dihydroorotate dehydrogenase 2 | 0.49 | Synpcc7942_1898 | leuC | isopropylmalate isomerase large subunit | — | — |
| Bifidobacterium breve UCC2003 | 0.21 | BBR_RS12895 | | quinone-dependent dihydroorotate dehydrogenase | 0.55 | BBR_RS19630 | | 3-isopropylmalate dehydratase large subunit | low | > 34 |
Not shown: 0 genomes with orthologs for PGA1_c12150 only; 11 genomes with orthologs for PGA1_c29780 only