Conservation of cofitness between PGA1_c29490 and PGA1_c12150 in Phaeobacter inhibens DSM 17395

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Phaeobacter inhibens DSM 17395 1.0 PGA1_c29490 dihydroxy-acid dehydratase LivD 1.0 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.87 15
Sinorhizobium meliloti 1021 0.77 SMc04045 dihydroxy-acid dehydratase 0.47 SMc02245 dihydroorotate dehydrogenase 2 0.88 56
Rhizobium sp. OAE497 0.76 ABIE40_RS08005 dihydroxy-acid dehydratase 0.44 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Agrobacterium fabrum C58 0.76 Atu1918 dihydroxy-acid dehydratase 0.46 Atu0486 dihydroorotate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.76 TX73_007515 dihydroxy-acid dehydratase 0.41 TX73_004110 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.75 PfGW456L13_973 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.36 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2E3 0.75 AO353_08345 dihydroxy-acid dehydratase 0.36 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens SBW25-INTG 0.75 PFLU_RS28535 dihydroxy-acid dehydratase 0.36 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.75 PFLU_RS28535 dihydroxy-acid dehydratase 0.36 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.75 Pf1N1B4_2303 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.36 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas sp. RS175 0.75 PFR28_04278 Dihydroxy-acid dehydratase 0.35 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas simiae WCS417 0.74 PS417_26890 dihydroxy-acid dehydratase 0.36 PS417_20935 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.74 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.36 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas sp. S08-1 0.74 OH686_14100 dihydroxy-acid dehydratase 0.36 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Pseudomonas fluorescens FW300-N2C3 0.74 AO356_13250 dihydroxy-acid dehydratase 0.35 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas putida KT2440 0.74 PP_5128 Dihydroxy-acid dehydratase 0.34 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Magnetospirillum magneticum AMB-1 0.74 AMB_RS12770 dihydroxy-acid dehydratase 0.45 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Synechococcus elongatus PCC 7942 0.74 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase 0.30 Synpcc7942_0290 pyrD dihydroorotate dehydrogenase 2 — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.74 Psyr_0469 dihydroxyacid dehydratase 0.35 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas syringae pv. syringae B728a 0.74 Psyr_0469 dihydroxyacid dehydratase 0.35 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas stutzeri RCH2 0.74 Psest_0234 dihydroxy-acid dehydratase 0.38 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 — —
Paraburkholderia sabiae LMG 24235 0.73 QEN71_RS21095 dihydroxy-acid dehydratase 0.34 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.73 ABZR87_RS00240 dihydroxy-acid dehydratase 0.35 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.73 Ac3H11_955 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.37 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Azospirillum brasilense Sp245 0.73 AZOBR_RS15015 dihydroxy-acid dehydratase 0.44 AZOBR_RS13520 dihydroorotate dehydrogenase low > 97
Xanthomonas campestris pv. campestris strain 8004 0.73 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.34 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Vibrio cholerae E7946 ATCC 55056 0.73 CSW01_00140 dihydroxy-acid dehydratase 0.33 CSW01_07490 dihydroorotate dehydrogenase (quinone) low > 62
Paraburkholderia bryophila 376MFSha3.1 0.72 H281DRAFT_05312 dihydroxyacid dehydratase 0.34 H281DRAFT_00743 dihydroorotate oxidase A — —
Azospirillum sp. SherDot2 0.72 MPMX19_05356 Dihydroxy-acid dehydratase 0.47 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Paraburkholderia graminis OAS925 0.72 ABIE53_006513 dihydroxy-acid dehydratase 0.35 ABIE53_001954 dihydroorotate dehydrogenase — —
Dechlorosoma suillum PS 0.72 Dsui_1122 dihydroxy-acid dehydratase 0.35 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Caulobacter crescentus NA1000 0.72 CCNA_03139 dihydroxy-acid dehydratase 0.42 CCNA_00562 dihydroorotate dehydrogenase 0.84 64
Caulobacter crescentus NA1000 Δfur 0.72 CCNA_03139 dihydroxy-acid dehydratase 0.42 CCNA_00562 dihydroorotate dehydrogenase low > 67
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.71 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.31 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 78
Escherichia coli Nissle 1917 0.71 ECOLIN_RS21665 dihydroxy-acid dehydratase 0.33 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Escherichia fergusonii Becca 0.71 EFB2_04865 Dihydroxy-acid dehydratase 0.33 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Enterobacter sp. TBS_079 0.71 MPMX20_04499 Dihydroxy-acid dehydratase 0.33 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.84 58
Alteromonas macleodii MIT1002 0.71 MIT1002_04041 Dihydroxy-acid dehydratase 0.35 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) low > 70
Escherichia coli BW25113 0.71 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.33 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.79 67
Escherichia coli ECOR38 0.71 HEPCGN_13350 ilvD dihydroxy-acid dehydratase 0.33 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase low > 85
Escherichia coli ECRC62 0.71 BNILDI_04750 ilvD dihydroxy-acid dehydratase 0.33 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECOR27 0.71 NOLOHH_06775 ilvD dihydroxy-acid dehydratase 0.33 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.71 OHPLBJKB_04282 Dihydroxy-acid dehydratase 0.33 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) low > 73
Escherichia coli BL21 0.71 ECD_03649 dihydroxyacid dehydratase 0.33 ECD_00949 dihydro-orotate oxidase, FMN-linked low > 60
Escherichia coli ECRC99 0.71 KEDOAH_13510 ilvD dihydroxy-acid dehydratase 0.33 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC102 0.71 NIAGMN_12395 ilvD dihydroxy-acid dehydratase 0.33 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC101 0.71 OKFHMN_14640 ilvD dihydroxy-acid dehydratase 0.33 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC101 0.71 MCAODC_05145 ilvD dihydroxy-acid dehydratase 0.33 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC98 0.71 JDDGAC_18260 ilvD dihydroxy-acid dehydratase 0.33 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Enterobacter asburiae PDN3 0.71 EX28DRAFT_4443 dihydroxy-acid dehydratase 0.33 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Pectobacterium carotovorum WPP14 0.71 HER17_RS01075 dihydroxy-acid dehydratase 0.33 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.98 15
Klebsiella michiganensis M5al 0.71 BWI76_RS00975 dihydroxy-acid dehydratase 0.33 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.62 77
Pantoea sp. MT58 0.71 IAI47_01035 dihydroxy-acid dehydratase 0.33 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.79 71
Herbaspirillum seropedicae SmR1 0.70 HSERO_RS02650 dihydroxy-acid dehydratase 0.34 HSERO_RS16155 dihydroorotate dehydrogenase — —
Dickeya dadantii 3937 0.70 DDA3937_RS20155 dihydroxy-acid dehydratase 0.34 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase low > 74
Burkholderia phytofirmans PsJN 0.70 BPHYT_RS10100 dihydroxy-acid dehydratase 0.35 BPHYT_RS08565 dihydroorotate dehydrogenase 0.52 86
Rhodospirillum rubrum S1H 0.70 Rru_A1786 Dihydroxy-acid dehydratase (NCBI) 0.41 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.86 23
Dickeya dianthicola 67-19 0.70 HGI48_RS20295 dihydroxy-acid dehydratase 0.33 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.68 70
Dickeya dianthicola ME23 0.69 DZA65_RS21335 dihydroxy-acid dehydratase 0.33 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.77 36
Serratia liquefaciens MT49 0.69 IAI46_24345 dihydroxy-acid dehydratase 0.32 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.74 15
Shewanella sp. ANA-3 0.69 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.36 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.88 72
Shewanella loihica PV-4 0.69 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.33 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) low > 60
Castellaniella sp019104865 MT123 0.69 ABCV34_RS14810 dihydroxy-acid dehydratase 0.36 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase — —
Shewanella amazonensis SB2B 0.69 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.33 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) low > 62
Shewanella oneidensis MR-1 0.68 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.36 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) low > 76
Erwinia tracheiphila SCR3 0.68 LU632_RS24400 ilvD dihydroxy-acid dehydratase 0.33 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.60 74
Rahnella sp. WP5 0.66 EX31_RS15005 dihydroxy-acid dehydratase 0.32 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.94 53
Hydrogenophaga sp. GW460-11-11-14-LB1 0.61 GFF2073 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.36 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 90
Bifidobacterium breve UCC2003 0.55 BBR_RS17635 dihydroxy-acid dehydratase 0.21 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase low > 34
Mycobacterium tuberculosis H37Rv 0.33 Rv0189c Probable dihydroxy-acid dehydratase IlvD (dad) 0.32 Rv2139 Probable dihydroorotate dehydrogenase PyrD — —
Dinoroseobacter shibae DFL-12 0.32 Dshi_0129 dihydroxy-acid dehydratase (RefSeq) 0.70 Dshi_0847 Dihydroorotate oxidase (RefSeq) — —
Variovorax sp. OAS795 0.31 ABID97_RS17500 dihydroxy-acid dehydratase 0.35 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. SCN45 0.31 GFF471 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.36 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS16210 dihydroxy-acid dehydratase 0.34 RR42_RS07465 dihydroorotate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.30 RALBFv3_RS04535 dihydroxy-acid dehydratase 0.36 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum UW163 0.30 UW163_RS09135 dihydroxy-acid dehydratase 0.36 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.30 RPSI07_RS12840 dihydroxy-acid dehydratase 0.35 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.30 RS_RS12105 dihydroxy-acid dehydratase 0.35 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Acinetobacter radioresistens SK82 0.30 MPMX26_03019 Dihydroxy-acid dehydratase 0.36 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) low > 36
Bosea sp. OAE506 0.30 ABIE41_RS15690 dihydroxy-acid dehydratase 0.40 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase — —
Sphingomonas koreensis DSMZ 15582 0.29 Ga0059261_4216 Dihydroxyacid dehydratase/phosphogluconate dehydratase 0.37 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.28 ABZR88_RS11575 dihydroxy-acid dehydratase 0.36 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.28 OKGIIK_13600 ilvD dihydroxy-acid dehydratase 0.37 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.27 Echvi_2055 dihydroxy-acid dehydratase 0.37 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.27 CA264_06935 dihydroxy-acid dehydratase 0.35 CA264_00865 dihydroorotate dehydrogenase (quinone) low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.27 CA265_RS15795 dihydroxy-acid dehydratase 0.37 CA265_RS14005 dihydroorotate dehydrogenase (quinone) — —
Dyella japonica UNC79MFTsu3.2 0.27 ABZR86_RS15945 dihydroxy-acid dehydratase 0.36 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase — —
Lysobacter sp. OAE881 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.33 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.26 LRK55_RS09960 dihydroxy-acid dehydratase 0.37 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.26 LRK54_RS10320 dihydroxy-acid dehydratase 0.37 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.25 A4249_RS10030 dihydroxy-acid dehydratase 0.44 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase — —

Not shown: 11 genomes with orthologs for PGA1_c29490 only; 1 genomes with orthologs for PGA1_c12150 only