Conservation of cofitness between CSW01_01010 and CSW01_12845 in Vibrio cholerae E7946 ATCC 55056

95 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01010 oligopeptidase A 1.0 CSW01_12845 metalloprotease PmbA 0.64 7
Klebsiella pneumoniae MKP103 0.73 KDGMDA_07425 oligopeptidase A 0.63 KDGMDA_11330 metalloprotease PmbA low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.72 GFF517 Oligopeptidase A (EC 3.4.24.70) 0.64 GFF904 TldE protein, part of TldE/TldD proteolytic complex low > 78
Enterobacter asburiae PDN3 0.72 EX28DRAFT_4063 Zn-dependent oligopeptidases 0.64 EX28DRAFT_3422 Predicted Zn-dependent proteases and their inactivated homologs low > 76
Escherichia coli ECRC62 0.72 BNILDI_03210 prlC oligopeptidase A 0.64 BNILDI_07325 pmbA metalloprotease PmbA low > 75
Escherichia coli BL21 0.72 ECD_03347 oligopeptidase A 0.64 ECD_04103 putative antibiotic peptide MccB17 maturation peptidase low > 61
Escherichia coli ECOR27 0.72 NOLOHH_08350 prlC oligopeptidase A 0.64 NOLOHH_04185 pmbA metalloprotease PmbA 0.53 12
Pantoea sp. MT58 0.72 IAI47_01345 oligopeptidase A 0.62 IAI47_02765 metalloprotease PmbA low > 76
Pantoea agglomerans CFBP13505 P0401 0.72 PagCFBP13505_RS17845 oligopeptidase A 0.62 PagCFBP13505_RS11365 metalloprotease PmbA low > 74
Escherichia fergusonii Becca 0.72 EFB2_00317 Oligopeptidase A 0.64 EFB2_04298 Metalloprotease PmbA low > 86
Escherichia coli ECOR38 0.72 HEPCGN_15325 prlC oligopeptidase A 0.64 HEPCGN_10125 pmbA metalloprotease PmbA low > 88
Escherichia coli BW25113 0.72 b3498 prlC oligopeptidase A (NCBI) 0.64 b4235 pmbA predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) 0.55 1
Escherichia coli HS(pFamp)R (ATCC 700891) 0.72 OHPLBJKB_00205 Oligopeptidase A 0.64 OHPLBJKB_03800 Metalloprotease PmbA low > 74
Escherichia coli Nissle 1917 0.72 ECOLIN_RS19985 oligopeptidase A 0.64 ECOLIN_RS24570 metalloprotease PmbA low > 55
Enterobacter sp. TBS_079 0.72 MPMX20_04397 Oligopeptidase A 0.64 MPMX20_00517 Metalloprotease PmbA low > 85
Escherichia coli ECRC100 0.72 OKFHMN_16415 prlC oligopeptidase A 0.64 OKFHMN_11925 pmbA metalloprotease PmbA low > 79
Escherichia coli ECRC101 0.72 MCAODC_06930 prlC oligopeptidase A 0.64 MCAODC_02430 pmbA metalloprotease PmbA low > 88
Escherichia coli ECRC99 0.72 KEDOAH_11730 prlC oligopeptidase A 0.64 KEDOAH_16230 pmbA metalloprotease PmbA — —
Escherichia coli ECRC102 0.72 NIAGMN_14180 prlC oligopeptidase A 0.64 NIAGMN_09775 pmbA metalloprotease PmbA low > 80
Escherichia coli ECRC98 0.72 JDDGAC_20045 prlC oligopeptidase A 0.64 JDDGAC_15565 pmbA metalloprotease PmbA 0.28 75
Klebsiella michiganensis M5al 0.72 BWI76_RS26610 oligopeptidase A 0.64 BWI76_RS02850 metalloprotease PmbA low > 92
Dickeya dadantii 3937 0.72 DDA3937_RS21265 oligopeptidase A 0.62 DDA3937_RS01500 metalloprotease PmbA low > 74
Serratia liquefaciens MT49 0.71 IAI46_24210 oligopeptidase A 0.65 IAI46_22575 metalloprotease PmbA low > 86
Erwinia tracheiphila SCR3 0.71 LU632_RS19470 prlC oligopeptidase A 0.59 LU632_RS02145 pmbA metalloprotease PmbA low > 74
Erwinia tracheiphila HP pepo 2.2 0.71 IJEDHG_12590 prlC oligopeptidase A 0.59 IJEDHG_06770 pmbA metalloprotease PmbA low > 61
Dickeya dianthicola ME23 0.71 DZA65_RS00035 oligopeptidase A 0.62 DZA65_RS01480 metalloprotease PmbA low > 75
Erwinia amylovora T8 0.71 OLJFJH_04530 Oligopeptidase A 0.63 OLJFJH_02355 metalloprotease PmbA low > 58
Pectobacterium carotovorum WPP14 0.71 HER17_RS21300 oligopeptidase A 0.66 HER17_RS20090 metalloprotease PmbA low > 75
Rahnella sp. WP5 0.70 EX31_RS05165 oligopeptidase A 0.64 EX31_RS12320 metalloprotease PmbA low > 89
Dickeya dianthicola 67-19 0.70 HGI48_RS00045 oligopeptidase A 0.62 HGI48_RS01415 metalloprotease PmbA low > 71
Shewanella loihica PV-4 0.68 Shew_3657 oligopeptidase A (RefSeq) 0.56 Shew_0416 peptidase U62, modulator of DNA gyrase (RefSeq) 0.72 3
Shewanella sp. ANA-3 0.67 Shewana3_4051 oligopeptidase A (RefSeq) 0.58 Shewana3_3631 microcin-processing peptidase 1 (RefSeq) low > 73
Shewanella amazonensis SB2B 0.67 Sama_3546 oligopeptidase A (RefSeq) 0.58 Sama_0482 PmbA protein (RefSeq) 0.41 2
Shewanella oneidensis MR-1 0.67 SO4699 prlC oligopeptidase A (NCBI ptt file) 0.58 SO4078 pmbA pmba protein (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.66 MIT1002_03633 Oligopeptidase A 0.54 MIT1002_00230 peptidase PmbA low > 70
Kangiella aquimarina DSM 16071 0.59 B158DRAFT_0457 Zn-dependent oligopeptidases 0.43 B158DRAFT_2075 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 low > 40
Pseudomonas aeruginosa PA14 0.58 IKLFDK_25215 oligopeptidase A 0.47 IKLFDK_01720 metalloprotease PmbA low > 100
Pseudomonas stutzeri RCH2 0.57 Psest_4320 Zn-dependent oligopeptidases 0.46 Psest_3318 Predicted Zn-dependent proteases and their inactivated homologs 0.22 38
Pseudomonas segetis P6 0.57 MPMX49_00359 Oligopeptidase A 0.46 MPMX49_03863 Metalloprotease PmbA low > 75
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_0045 oligopeptidase A, Metallo peptidase, MEROPS family M03A 0.47 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 low > 86
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_0045 oligopeptidase A, Metallo peptidase, MEROPS family M03A 0.47 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 low > 86
Pseudomonas fluorescens GW456-L13 0.57 PfGW456L13_624 Oligopeptidase A (EC 3.4.24.70) 0.47 PfGW456L13_5024 TldE protein, part of TldE/TldD proteolytic complex low > 87
Pseudomonas sp. S08-1 0.56 OH686_12360 Oligopeptidase A 0.47 OH686_08570 TldE protein, part of TldE/TldD proteolytic complex low > 80
Pseudomonas sp. SVBP6 0.56 COO64_RS02335 prlC oligopeptidase A 0.47 COO64_RS04235 pmbA metalloprotease PmbA low > 93
Pseudomonas sp. DMC3 0.56 GFF663 Oligopeptidase A 0.47 GFF1818 Metalloprotease PmbA low > 89
Pseudomonas simiae WCS417 0.56 PS417_00245 oligopeptidase A 0.47 PS417_04295 peptidase PmbA 0.49 7
Pseudomonas putida KT2440 0.56 PP_0096 oligopeptidase A 0.49 PP_0942 regulatory protease low > 96
Pseudomonas fluorescens SBW25 0.56 PFLU_RS00240 oligopeptidase A 0.48 PFLU_RS04350 metalloprotease PmbA low > 109
Pseudomonas fluorescens SBW25-INTG 0.56 PFLU_RS00240 oligopeptidase A 0.48 PFLU_RS04350 metalloprotease PmbA 0.28 23
Pseudomonas sp. RS175 0.56 PFR28_04699 Oligopeptidase A 0.48 PFR28_00163 Metalloprotease PmbA low > 88
Pseudomonas fluorescens FW300-N1B4 0.56 Pf1N1B4_1844 Oligopeptidase A (EC 3.4.24.70) 0.47 Pf1N1B4_1090 TldE protein, part of TldE/TldD proteolytic complex 0.42 15
Pseudomonas fluorescens FW300-N2E3 0.56 AO353_10775 oligopeptidase A 0.47 AO353_05205 peptidase PmbA low > 101
Pseudomonas lactucae CFBP13502 0.56 GEMAOFIL_00254 Oligopeptidase A 0.48 GEMAOFIL_01064 Metalloprotease PmbA low > 93
Pseudomonas sp. BP01 0.56 JOY50_RS21245 prlC oligopeptidase A 0.48 JOY50_RS11080 pmbA metalloprotease PmbA low > 84
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_4091 Oligopeptidase A (EC 3.4.24.70) 0.48 Pf6N2E2_3278 TldE protein, part of TldE/TldD proteolytic complex 0.26 28
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_11120 oligopeptidase A 0.48 AO356_07085 peptidase PmbA 0.22 100
Methylophilus sp. DMC18 0.52 GFF2262 Oligopeptidase A 0.46 GFF830 Metalloprotease PmbA low > 43
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_15380 dcp oligopeptidase A 0.45 OKGIIK_10260 pmbA metalloprotease PmbA low > 53
Herbaspirillum seropedicae SmR1 0.48 HSERO_RS07290 oligopeptidase A 0.42 HSERO_RS09265 peptidase C69 0.45 8
Paraburkholderia graminis OAS925 0.48 ABIE53_002798 oligopeptidase A 0.42 ABIE53_003116 PmbA protein 0.59 3
Dechlorosoma suillum PS 0.48 Dsui_0046 Zn-dependent oligopeptidase 0.44 Dsui_1234 putative Zn-dependent protease-like protein 0.63 11
Paraburkholderia sabiae LMG 24235 0.48 QEN71_RS05695 M3 family metallopeptidase 0.42 QEN71_RS04270 metalloprotease PmbA low > 153
Dyella japonica UNC79MFTsu3.2 0.48 ABZR86_RS14940 M3 family metallopeptidase 0.45 ABZR86_RS21700 metalloprotease PmbA 0.62 12
Burkholderia phytofirmans PsJN 0.48 BPHYT_RS12875 oligopeptidase A 0.41 BPHYT_RS14705 peptidase C69 low > 109
Rhodanobacter sp000427505 FW510-R12 0.48 LRK53_RS02390 M3 family metallopeptidase 0.45 LRK53_RS06580 metalloprotease PmbA low > 59
Cupriavidus basilensis FW507-4G11 0.47 RR42_RS07340 oligopeptidase A 0.40 RR42_RS14750 peptidase PMbA low > 128
Ralstonia solanacearum GMI1000 0.47 RS_RS08035 oligopeptidase A 0.41 RS_RS04700 metalloprotease PmbA low > 80
Ralstonia sp. UNC404CL21Col 0.47 ABZR87_RS13490 M3 family metallopeptidase 0.42 ABZR87_RS09660 metalloprotease PmbA 0.40 32
Xanthomonas campestris pv. campestris strain 8004 0.47 Xcc-8004.4539.1 Oligopeptidase A (EC 3.4.24.70) 0.45 Xcc-8004.1885.1 TldE protein, part of TldE/TldD proteolytic complex low > 74
Ralstonia solanacearum UW163 0.47 UW163_RS15000 oligopeptidase A 0.42 UW163_RS15845 metalloprotease PmbA — —
Ralstonia solanacearum IBSBF1503 0.47 RALBFv3_RS01690 oligopeptidase A 0.42 RALBFv3_RS13965 metalloprotease PmbA low > 76
Rhodanobacter denitrificans MT42 0.47 LRK55_RS08380 M3 family metallopeptidase 0.45 LRK55_RS03125 metalloprotease PmbA 0.90 35
Rhodanobacter denitrificans FW104-10B01 0.47 LRK54_RS08615 M3 family metallopeptidase 0.44 LRK54_RS03375 metalloprotease PmbA 0.85 3
Ralstonia solanacearum PSI07 0.47 RPSI07_RS15795 oligopeptidase A 0.42 RPSI07_RS19505 metalloprotease PmbA low > 81
Paraburkholderia bryophila 376MFSha3.1 0.46 H281DRAFT_00461 oligopeptidase A Metallo peptidase. MEROPS family M03A 0.42 H281DRAFT_04304 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 low > 103
Variovorax sp. OAS795 0.44 ABID97_RS14080 M3 family metallopeptidase 0.45 ABID97_RS20695 metalloprotease PmbA 0.86 2
Variovorax sp. SCN45 0.44 GFF963 Oligopeptidase A (EC 3.4.24.70) 0.44 GFF4697 TldE protein, part of TldE/TldD proteolytic complex low > 127
Acidovorax sp. GW101-3H11 0.43 Ac3H11_4097 Oligopeptidase A (EC 3.4.24.70) 0.42 Ac3H11_3262 TldE protein, part of TldE/TldD proteolytic complex low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.43 GFF4214 Oligopeptidase A (EC 3.4.24.70) 0.41 GFF3655 TldE protein, part of TldE/TldD proteolytic complex low > 90
Castellaniella sp019104865 MT123 0.42 ABCV34_RS04180 M3 family metallopeptidase 0.44 ABCV34_RS10610 metalloprotease PmbA low > 48
Bacteroides stercoris CC31F 0.35 HMPREF1181_RS06150 M3 family metallopeptidase 0.17 HMPREF1181_RS03170 TldD/PmbA family protein low > 56
Bacteroides thetaiotaomicron VPI-5482 0.32 BT4262 peptidyl-dipeptidase (NCBI ptt file) 0.18 BT3649 putative modulator of DNA gyrase (NCBI ptt file) low > 81
Parabacteroides merdae CL09T00C40 0.29 HMPREF1078_RS14650 M3 family metallopeptidase 0.15 HMPREF1078_RS03625 TldD/PmbA family protein low > 61
Sinorhizobium meliloti 1021 0.27 SMc04403 peptidyl-dipeptidase A protein 0.27 SMc00897 PMBA protein low > 103
Agrobacterium fabrum C58 0.27 Atu2664 peptidyl-dipeptidase 0.25 Atu0693 PmbA/TldD related protein low > 89
Rhizobium sp. OAE497 0.27 ABIE40_RS18135 M3 family metallopeptidase 0.25 ABIE40_RS03780 TldD/PmbA family protein 0.84 4
Rhodopseudomonas palustris CGA009 0.26 TX73_004495 M3 family metallopeptidase 0.28 TX73_005930 TldD/PmbA family protein 0.31 73
Phaeobacter inhibens DSM 17395 0.26 PGA1_c26590 peptidyl-dipeptidase Dcp 0.28 PGA1_c33480 protein PmbA — —
Azospirillum brasilense Sp245 0.24 AZOBR_RS23485 peptidase M3 0.32 AZOBR_RS11930 modulator protein low > 97
Dinoroseobacter shibae DFL-12 0.22 Dshi_2973 Peptidyl-dipeptidase Dcp (RefSeq) 0.25 Dshi_0064 peptidase U62 modulator of DNA gyrase (RefSeq) low > 64
Caulobacter crescentus NA1000 0.22 CCNA_03816 peptidyl-dipeptidase DCP 0.28 CCNA_00311 Zn-dependent protease family protein low > 66
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_03816 peptidyl-dipeptidase DCP 0.28 CCNA_00311 Zn-dependent protease family protein low > 67
Sphingomonas koreensis DSMZ 15582 0.22 Ga0059261_2479 Zn-dependent oligopeptidases 0.31 Ga0059261_0810 Predicted Zn-dependent proteases and their inactivated homologs low > 68
Pontibacter actiniarum KMM 6156, DSM 19842 0.21 CA264_01885 peptidase M3 0.06 CA264_16645 peptidase C69 low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS12525 M3 family metallopeptidase 0.25 A4249_RS09195 TldD/PmbA family protein low > 48
Lysobacter sp. OAE881 0.21 ABIE51_RS09155 M3 family metallopeptidase 0.43 ABIE51_RS06805 metalloprotease PmbA low > 62

Not shown: 11 genomes with orthologs for CSW01_01010 only; 6 genomes with orthologs for CSW01_12845 only