Conservation of cofitness between CSW01_00430 and CSW01_05645 in Vibrio cholerae E7946 ATCC 55056

101 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_00430 NAD(P)/FAD-dependent oxidoreductase 1.0 CSW01_05645 biotin synthase 0.50 11
Shewanella sp. ANA-3 0.62 Shewana3_0055 hypothetical protein (RefSeq) 0.65 Shewana3_2519 biotin synthase (RefSeq) low > 73
Alteromonas macleodii MIT1002 0.61 MIT1002_00118 N-methyltryptophan oxidase 0.68 MIT1002_01379 Biotin synthase low > 70
Shewanella loihica PV-4 0.61 Shew_3802 hypothetical protein (RefSeq) 0.63 Shew_1719 biotin synthase (RefSeq) — —
Pantoea agglomerans CFBP13505 P0401 0.61 PagCFBP13505_RS17875 NAD(P)/FAD-dependent oxidoreductase 0.69 PagCFBP13505_RS03770 biotin synthase BioB 0.65 19
Shewanella oneidensis MR-1 0.61 SO0054 conserved hypothetical protein TIGR00275 (NCBI ptt file) 0.65 SO2740 bioB biotin synthase (NCBI ptt file) — —
Dickeya dianthicola 67-19 0.60 HGI48_RS21025 NAD(P)/FAD-dependent oxidoreductase 0.71 HGI48_RS08675 biotin synthase BioB low > 71
Pantoea sp. MT58 0.60 IAI47_01370 NAD(P)/FAD-dependent oxidoreductase 0.70 IAI47_13530 biotin synthase BioB low > 76
Shewanella amazonensis SB2B 0.60 Sama_0064 hypothetical protein (RefSeq) 0.66 Sama_1438 biotin synthase (RefSeq) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.59 GFF523 NAD(FAD)-utilizing dehydrogenases 0.70 GFF671 Biotin synthase (EC 2.8.1.6) 0.52 15
Rahnella sp. WP5 0.59 EX31_RS05140 NAD(P)/FAD-dependent oxidoreductase 0.69 EX31_RS23695 biotin synthase BioB low > 89
Pectobacterium carotovorum WPP14 0.59 HER17_RS21340 NAD(P)/FAD-dependent oxidoreductase 0.69 HER17_RS13460 biotin synthase BioB low > 75
Dickeya dianthicola ME23 0.59 DZA65_RS22010 NAD(P)/FAD-dependent oxidoreductase 0.70 DZA65_RS08965 biotin synthase BioB low > 75
Dickeya dadantii 3937 0.58 DDA3937_RS00340 NAD(P)/FAD-dependent oxidoreductase 0.71 DDA3937_RS08510 biotin synthase BioB low > 74
Serratia liquefaciens MT49 0.58 IAI46_24145 NAD(P)/FAD-dependent oxidoreductase 0.69 IAI46_06525 biotin synthase BioB low > 87
Erwinia amylovora T8 0.58 OLJFJH_04505 aminoacetone oxidase family FAD-binding enzyme 0.69 OLJFJH_16760 biotin synthase BioB low > 58
Erwinia tracheiphila HP pepo 2.2 0.58 IJEDHG_12610 aminoacetone oxidase family FAD-binding enzyme 0.71 IJEDHG_19565 bioB biotin synthase BioB — —
Erwinia tracheiphila SCR3 0.58 LU632_RS19445 NAD(P)/FAD-dependent oxidoreductase 0.71 LU632_RS09130 bioB biotin synthase BioB — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.58 OHPLBJKB_00211 hypothetical protein 0.70 OHPLBJKB_02938 Biotin synthase low > 74
Escherichia coli ECOR27 0.58 NOLOHH_08380 yhiN Uncharacterized protein YhiN 0.70 NOLOHH_22770 bioB biotin synthase BioB low > 76
Escherichia coli BW25113 0.58 b3492 yhiN predicted oxidoreductase with FAD/NAD(P)-binding domain (NCBI) 0.70 b0775 bioB biotin synthase (NCBI) low > 76
Escherichia coli ECRC101 0.58 MCAODC_06960 yhiN Uncharacterized protein YhiN 0.69 MCAODC_25615 bioB biotin synthase BioB low > 87
Escherichia coli ECOR38 0.58 HEPCGN_15360 yhiN Uncharacterized protein YhiN 0.70 HEPCGN_01640 bioB biotin synthase BioB low > 88
Enterobacter sp. TBS_079 0.58 MPMX20_04392 hypothetical protein 0.69 MPMX20_01403 Biotin synthase low > 85
Escherichia coli ECRC99 0.58 KEDOAH_11700 yhiN Uncharacterized protein YhiN 0.69 KEDOAH_21510 bioB biotin synthase BioB — —
Escherichia coli ECRC98 0.58 JDDGAC_20075 yhiN Uncharacterized protein YhiN 0.69 JDDGAC_10035 bioB biotin synthase BioB low > 87
Escherichia coli ECRC102 0.58 NIAGMN_14210 yhiN Uncharacterized protein YhiN 0.69 NIAGMN_04445 bioB biotin synthase BioB low > 80
Escherichia coli ECRC100 0.58 OKFHMN_16445 yhiN Uncharacterized protein YhiN 0.69 OKFHMN_06400 bioB biotin synthase BioB low > 79
Enterobacter asburiae PDN3 0.58 EX28DRAFT_4070 flavoprotein, HI0933 family 0.70 EX28DRAFT_2216 biotin synthase (EC 2.8.1.6) 0.43 55
Escherichia coli ECRC62 0.58 BNILDI_03180 yhiN Uncharacterized protein YhiN 0.70 BNILDI_21040 bioB biotin synthase BioB low > 75
Escherichia coli Nissle 1917 0.58 ECOLIN_RS19955 NAD(P)/FAD-dependent oxidoreductase 0.69 ECOLIN_RS04130 biotin synthase BioB low > 55
Escherichia coli BL21 0.58 ECD_03341 putative oxidoreductase 0.70 ECD_00742 biotin synthase low > 61
Escherichia fergusonii Becca 0.58 EFB2_00323 hypothetical protein 0.69 EFB2_03330 Biotin synthase low > 86
Klebsiella michiganensis M5al 0.57 BWI76_RS26565 membrane protein 0.69 BWI76_RS08760 biotin synthase low > 92
Klebsiella pneumoniae MKP103 0.57 KDGMDA_07395 aminoacetone oxidase family FAD-binding enzyme 0.70 KDGMDA_17025 biotin synthase BioB low > 95
Pseudomonas stutzeri RCH2 0.56 Psest_0341 flavoprotein, HI0933 family 0.70 Psest_0411 biotin synthetase low > 67
Pseudomonas sp. DMC3 0.55 GFF143 putative protein 0.68 GFF76 Biotin synthase low > 89
Pseudomonas aeruginosa PUPa3 0.55 DQ20_RS36525 NAD(P)/FAD-dependent oxidoreductase 0.70 DQ20_RS36825 bioB;go_function=biotin biotin synthase BioB low > 101
Pseudomonas aeruginosa MRSN321 0.55 DY961_RS22815 NAD(P)/FAD-dependent oxidoreductase 0.70 DY961_RS22505 bioB;go_function=biotin biotin synthase BioB — —
Pseudomonas aeruginosa PA14 0.55 IKLFDK_22630 NAD(P)/FAD-dependent oxidoreductase 0.70 IKLFDK_22935 biotin synthase BioB low > 98
Dyella japonica UNC79MFTsu3.2 0.54 ABZR86_RS00415 NAD(P)/FAD-dependent oxidoreductase 0.57 ABZR86_RS15840 biotin synthase BioB low > 74
Rhodanobacter sp. FW510-T8 0.54 OKGIIK_03505 yhiN NAD(P)/FAD-dependent oxidoreductase 0.55 OKGIIK_13650 bioB biotin synthase BioB low > 53
Pseudomonas sp. RS175 0.54 PFR28_04173 hypothetical protein 0.69 PFR28_04103 Biotin synthase low > 88
Pseudomonas segetis P6 0.54 MPMX49_00673 hypothetical protein 0.69 MPMX49_00759 Biotin synthase low > 75
Pseudomonas fluorescens FW300-N2C3 0.54 AO356_13765 hypothetical protein 0.69 AO356_14135 biotin synthase low > 104
Pseudomonas orientalis W4I3 0.54 QF045_RS00760 NAD(P)/FAD-dependent oxidoreductase 0.68 QF045_RS00415 biotin synthase BioB low > 93
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_4672 FIG00953568: hypothetical protein 0.69 Pf6N2E2_4759 Biotin synthase (EC 2.8.1.6) low > 103
Pseudomonas fluorescens FW300-N1B4 0.54 Pf1N1B4_2411 FIG00953568: hypothetical protein 0.69 Pf1N1B4_2487 Biotin synthase (EC 2.8.1.6) low > 87
Rhodanobacter denitrificans MT42 0.54 LRK55_RS14395 NAD(P)/FAD-dependent oxidoreductase 0.54 LRK55_RS09900 biotin synthase BioB low > 63
Pseudomonas simiae WCS417 0.54 PS417_26375 membrane protein 0.68 PS417_26005 biotin synthase low > 88
Kangiella aquimarina DSM 16071 0.54 B158DRAFT_1203 flavoprotein, HI0933 family 0.65 B158DRAFT_0864 biotin synthase (EC 2.8.1.6) — —
Pseudomonas fluorescens SBW25-INTG 0.54 PFLU_RS28025 NAD(P)/FAD-dependent oxidoreductase 0.68 PFLU_RS27650 biotin synthase BioB low > 109
Pseudomonas fluorescens SBW25 0.54 PFLU_RS28025 NAD(P)/FAD-dependent oxidoreductase 0.68 PFLU_RS27650 biotin synthase BioB low > 109
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_07855 hypothetical protein 0.69 AO353_07525 biotin synthase low > 101
Pseudomonas lactucae CFBP13502 0.53 GEMAOFIL_05401 hypothetical protein 0.68 GEMAOFIL_05322 Biotin synthase low > 96
Pseudomonas fluorescens GW456-L13 0.53 PfGW456L13_1077 FIG00953568: hypothetical protein 0.68 PfGW456L13_1147 Biotin synthase (EC 2.8.1.6) low > 87
Pseudomonas sp. S08-1 0.53 OH686_10655 Uncharacterized protein YhiN 0.69 OH686_10355 biotin synthase low > 80
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS14680 NAD(P)/FAD-dependent oxidoreductase 0.54 LRK54_RS10260 biotin synthase BioB low > 59
Pseudomonas putida KT2440 0.52 PP_4953 putative oxidoreductase with FAD/NAD(P)-binding domain 0.70 PP_0362 Biotin synthase low > 96
Pseudomonas sp. BP01 0.52 JOY50_RS09930 NAD(P)/FAD-dependent oxidoreductase 0.69 JOY50_RS17930 bioB biotin synthase BioB low > 84
Marinobacter adhaerens HP15 0.52 HP15_1033 flavoprotein, NADB Rossmann superfamily 0.65 HP15_2486 biotin synthase low > 73
Pseudomonas syringae pv. syringae B728a 0.52 Psyr_0515 HI0933-like protein 0.69 Psyr_4687 biotin synthase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.52 Psyr_0515 HI0933-like protein 0.69 Psyr_4687 biotin synthase low > 86
Xanthomonas campestris pv. campestris strain 8004 0.52 Xcc-8004.2264.1 FIG01211838: hypothetical protein 0.55 Xcc-8004.505.1 Biotin synthase (EC 2.8.1.6) low > 74
Rhizobium sp. OAE497 0.52 ABIE40_RS03215 NAD(P)/FAD-dependent oxidoreductase 0.52 ABIE40_RS21075 biotin synthase BioB low > 107
Lysobacter sp. OAE881 0.52 ABIE51_RS09810 NAD(P)/FAD-dependent oxidoreductase 0.58 ABIE51_RS01140 biotin synthase BioB low > 62
Pseudomonas sp. SVBP6 0.51 COO64_RS17615 NAD(P)/FAD-dependent oxidoreductase 0.69 COO64_RS22725 bioB biotin synthase BioB low > 93
Caulobacter crescentus NA1000 Δfur 0.51 CCNA_01545 NAD(FAD)-utilizing dehydrogenase 0.54 CCNA_03636 biotin synthase low > 67
Caulobacter crescentus NA1000 0.51 CCNA_01545 NAD(FAD)-utilizing dehydrogenase 0.54 CCNA_03636 biotin synthase low > 66
Magnetospirillum magneticum AMB-1 0.50 AMB_RS17480 NAD(P)/FAD-dependent oxidoreductase 0.57 AMB_RS13865 biotin synthase — —
Agrobacterium fabrum C58 0.49 Atu0603 hypothetical protein 0.56 Atu3997 biotin synthetase low > 89
Phaeobacter inhibens DSM 17395 0.48 PGA1_c09590 uncharacterized protein YhiN 0.54 PGA1_c09120 biotin synthase BioB low > 62
Acinetobacter baumannii LAC-4 0.48 RR41_RS15405 NAD(P)/FAD-dependent oxidoreductase 0.59 RR41_RS11800 biotin synthase BioB — —
Sphingomonas koreensis DSMZ 15582 0.48 Ga0059261_3388 flavoprotein, HI0933 family 0.56 Ga0059261_3989 biotin synthase (EC 2.8.1.6) low > 68
Variovorax sp. SCN45 0.47 GFF4713 Uncharacterized protein YhiN 0.56 GFF937 Biotin synthase (EC 2.8.1.6) low > 127
Acinetobacter radioresistens SK82 0.46 MPMX26_02534 hypothetical protein 0.59 MPMX26_01785 Biotin synthase low > 36
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF3659 NAD(FAD)-utilizing dehydrogenases 0.54 GFF3992 Biotin synthase (EC 2.8.1.6) — —
Herbaspirillum seropedicae SmR1 0.46 HSERO_RS04345 membrane protein 0.55 HSERO_RS12235 biotin synthase low > 78
Ralstonia solanacearum PSI07 0.45 RPSI07_RS13540 NAD(P)/FAD-dependent oxidoreductase 0.59 RPSI07_RS22850 biotin synthase BioB low > 81
Acidovorax sp. GW101-3H11 0.45 Ac3H11_3253 NAD(FAD)-utilizing dehydrogenases 0.55 Ac3H11_2272 Biotin synthase (EC 2.8.1.6) low > 79
Cupriavidus basilensis FW507-4G11 0.45 RR42_RS14990 membrane protein 0.56 RR42_RS00940 biotin synthase low > 128
Ralstonia sp. UNC404CL21Col 0.45 ABZR87_RS15620 NAD(P)/FAD-dependent oxidoreductase 0.59 ABZR87_RS06265 biotin synthase BioB low > 80
Ralstonia solanacearum UW163 0.44 UW163_RS09980 NAD(P)/FAD-dependent oxidoreductase 0.58 UW163_RS03115 biotin synthase BioB — —
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS03690 NAD(P)/FAD-dependent oxidoreductase 0.58 RALBFv3_RS10465 biotin synthase BioB low > 76
Ralstonia solanacearum GMI1000 0.44 RS_RS11135 NAD(P)/FAD-dependent oxidoreductase 0.59 RS_RS01305 biotin synthase low > 80
Sphingobium sp. HT1-2 0.44 GFF1279 Uncharacterized protein YhiN 0.53 GFF133 Biotin synthase (EC 2.8.1.6) low > 95
Paraburkholderia sabiae LMG 24235 0.44 QEN71_RS15210 NAD(P)/FAD-dependent oxidoreductase 0.60 QEN71_RS01085 biotin synthase BioB — —
Variovorax sp. OAS795 0.43 ABID97_RS20650 NAD(P)/FAD-dependent oxidoreductase 0.54 ABID97_RS13955 biotin synthase BioB low > 91
Paraburkholderia graminis OAS925 0.43 ABIE53_004862 putative Rossmann fold flavoprotein 0.58 ABIE53_000577 biotin synthase low > 113
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS33560 membrane protein 0.59 BPHYT_RS02150 biotin synthase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_06012 hypothetical protein 0.59 H281DRAFT_02097 biotin synthase low > 103
Castellaniella sp019104865 MT123 0.40 ABCV34_RS08895 NAD(P)/FAD-dependent oxidoreductase 0.56 ABCV34_RS15280 biotin synthase BioB low > 48
Pedobacter sp. GW460-11-11-14-LB5 0.40 CA265_RS07750 aminoacetone oxidase family FAD-binding enzyme 0.50 CA265_RS09475 biotin synthase BioB low > 88
Desulfovibrio vulgaris Miyazaki F 0.40 DvMF_0830 HI0933 family protein (RefSeq) 0.20 DvMF_1001 biotin synthase (RefSeq) low > 51
Mucilaginibacter yixingensis YX-36 DSM 26809 0.40 ABZR88_RS09315 NAD(P)/FAD-dependent oxidoreductase 0.47 ABZR88_RS10190 biotin synthase BioB low > 71
Desulfovibrio vulgaris Hildenborough JW710 0.38 DVU2234 conserved hypothetical protein TIGR00275 (TIGR) 0.24 DVU2558 bioB biotin synthase (Dmitry Rodionov) low > 55
Synechococcus elongatus PCC 7942 0.18 Synpcc7942_2067 hypothetical protein 0.51 Synpcc7942_0419 bioB biotin synthase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.17 CA264_05900 aminoacetone oxidase family FAD-binding enzyme 0.51 CA264_02425 biotin synthase BioB low > 74
Echinicola vietnamensis KMM 6221, DSM 17526 0.17 Echvi_3335 flavoprotein, HI0933 family 0.53 Echvi_2566 biotin synthetase low > 79
Synechocystis sp000284455 PCC 6803 0.16 SGL_RS15645 NAD(P)/FAD-dependent oxidoreductase 0.26 SGL_RS07055 biotin synthase BioB — —
Cellulophaga baltica 18 0.14 M666_RS02740 NAD(P)/FAD-dependent oxidoreductase 0.50 M666_RS03345 biotin synthase BioB — —
Rhodopseudomonas palustris CGA009 0.10 TX73_011285 NAD(P)/FAD-dependent oxidoreductase 0.53 TX73_010535 biotin synthase BioB 0.33 25

Not shown: 5 genomes with orthologs for CSW01_00430 only; 11 genomes with orthologs for CSW01_05645 only