Conservation of cofitness between CSW01_05645 and CSW01_00430 in Vibrio cholerae E7946 ATCC 55056

101 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_05645 biotin synthase 1.0 CSW01_00430 NAD(P)/FAD-dependent oxidoreductase 0.50 14
Erwinia tracheiphila HP pepo 2.2 0.71 IJEDHG_19565 bioB biotin synthase BioB 0.58 IJEDHG_12610 aminoacetone oxidase family FAD-binding enzyme — —
Erwinia tracheiphila SCR3 0.71 LU632_RS09130 bioB biotin synthase BioB 0.58 LU632_RS19445 NAD(P)/FAD-dependent oxidoreductase — —
Dickeya dadantii 3937 0.71 DDA3937_RS08510 biotin synthase BioB 0.58 DDA3937_RS00340 NAD(P)/FAD-dependent oxidoreductase low > 74
Dickeya dianthicola 67-19 0.71 HGI48_RS08675 biotin synthase BioB 0.60 HGI48_RS21025 NAD(P)/FAD-dependent oxidoreductase low > 71
Dickeya dianthicola ME23 0.70 DZA65_RS08965 biotin synthase BioB 0.59 DZA65_RS22010 NAD(P)/FAD-dependent oxidoreductase low > 75
Pseudomonas aeruginosa PUPa3 0.70 DQ20_RS36825 bioB;go_function=biotin biotin synthase BioB 0.55 DQ20_RS36525 NAD(P)/FAD-dependent oxidoreductase low > 101
Pseudomonas aeruginosa MRSN321 0.70 DY961_RS22505 bioB;go_function=biotin biotin synthase BioB 0.55 DY961_RS22815 NAD(P)/FAD-dependent oxidoreductase — —
Klebsiella pneumoniae MKP103 0.70 KDGMDA_17025 biotin synthase BioB 0.57 KDGMDA_07395 aminoacetone oxidase family FAD-binding enzyme low > 95
Pseudomonas aeruginosa PA14 0.70 IKLFDK_22935 biotin synthase BioB 0.55 IKLFDK_22630 NAD(P)/FAD-dependent oxidoreductase low > 98
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.70 GFF671 Biotin synthase (EC 2.8.1.6) 0.59 GFF523 NAD(FAD)-utilizing dehydrogenases 0.52 19
Pseudomonas putida KT2440 0.70 PP_0362 Biotin synthase 0.52 PP_4953 putative oxidoreductase with FAD/NAD(P)-binding domain low > 96
Escherichia coli ECOR38 0.70 HEPCGN_01640 bioB biotin synthase BioB 0.58 HEPCGN_15360 yhiN Uncharacterized protein YhiN low > 88
Escherichia coli ECOR27 0.70 NOLOHH_22770 bioB biotin synthase BioB 0.58 NOLOHH_08380 yhiN Uncharacterized protein YhiN low > 76
Escherichia coli BW25113 0.70 b0775 bioB biotin synthase (NCBI) 0.58 b3492 yhiN predicted oxidoreductase with FAD/NAD(P)-binding domain (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.70 OHPLBJKB_02938 Biotin synthase 0.58 OHPLBJKB_00211 hypothetical protein low > 74
Escherichia coli ECRC62 0.70 BNILDI_21040 bioB biotin synthase BioB 0.58 BNILDI_03180 yhiN Uncharacterized protein YhiN low > 75
Escherichia coli BL21 0.70 ECD_00742 biotin synthase 0.58 ECD_03341 putative oxidoreductase low > 61
Pseudomonas stutzeri RCH2 0.70 Psest_0411 biotin synthetase 0.56 Psest_0341 flavoprotein, HI0933 family low > 67
Enterobacter asburiae PDN3 0.70 EX28DRAFT_2216 biotin synthase (EC 2.8.1.6) 0.58 EX28DRAFT_4070 flavoprotein, HI0933 family low > 76
Pantoea sp. MT58 0.70 IAI47_13530 biotin synthase BioB 0.60 IAI47_01370 NAD(P)/FAD-dependent oxidoreductase low > 76
Pseudomonas sp. SVBP6 0.69 COO64_RS22725 bioB biotin synthase BioB 0.51 COO64_RS17615 NAD(P)/FAD-dependent oxidoreductase low > 93
Pseudomonas segetis P6 0.69 MPMX49_00759 Biotin synthase 0.54 MPMX49_00673 hypothetical protein low > 75
Escherichia fergusonii Becca 0.69 EFB2_03330 Biotin synthase 0.58 EFB2_00323 hypothetical protein low > 86
Escherichia coli Nissle 1917 0.69 ECOLIN_RS04130 biotin synthase BioB 0.58 ECOLIN_RS19955 NAD(P)/FAD-dependent oxidoreductase low > 55
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_4687 biotin synthase 0.52 Psyr_0515 HI0933-like protein low > 86
Serratia liquefaciens MT49 0.69 IAI46_06525 biotin synthase BioB 0.58 IAI46_24145 NAD(P)/FAD-dependent oxidoreductase low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_4687 biotin synthase 0.52 Psyr_0515 HI0933-like protein low > 86
Erwinia amylovora T8 0.69 OLJFJH_16760 biotin synthase BioB 0.58 OLJFJH_04505 aminoacetone oxidase family FAD-binding enzyme low > 58
Escherichia coli ECRC99 0.69 KEDOAH_21510 bioB biotin synthase BioB 0.58 KEDOAH_11700 yhiN Uncharacterized protein YhiN — —
Escherichia coli ECRC101 0.69 MCAODC_25615 bioB biotin synthase BioB 0.58 MCAODC_06960 yhiN Uncharacterized protein YhiN low > 87
Escherichia coli ECRC102 0.69 NIAGMN_04445 bioB biotin synthase BioB 0.58 NIAGMN_14210 yhiN Uncharacterized protein YhiN low > 80
Escherichia coli ECRC100 0.69 OKFHMN_06400 bioB biotin synthase BioB 0.58 OKFHMN_16445 yhiN Uncharacterized protein YhiN low > 79
Enterobacter sp. TBS_079 0.69 MPMX20_01403 Biotin synthase 0.58 MPMX20_04392 hypothetical protein low > 85
Escherichia coli ECRC98 0.69 JDDGAC_10035 bioB biotin synthase BioB 0.58 JDDGAC_20075 yhiN Uncharacterized protein YhiN low > 87
Pectobacterium carotovorum WPP14 0.69 HER17_RS13460 biotin synthase BioB 0.59 HER17_RS21340 NAD(P)/FAD-dependent oxidoreductase low > 75
Pseudomonas sp. BP01 0.69 JOY50_RS17930 bioB biotin synthase BioB 0.52 JOY50_RS09930 NAD(P)/FAD-dependent oxidoreductase low > 84
Pseudomonas sp. RS175 0.69 PFR28_04103 Biotin synthase 0.54 PFR28_04173 hypothetical protein low > 88
Pantoea agglomerans CFBP13505 P0401 0.69 PagCFBP13505_RS03770 biotin synthase BioB 0.61 PagCFBP13505_RS17875 NAD(P)/FAD-dependent oxidoreductase low > 74
Rahnella sp. WP5 0.69 EX31_RS23695 biotin synthase BioB 0.59 EX31_RS05140 NAD(P)/FAD-dependent oxidoreductase low > 89
Pseudomonas fluorescens FW300-N1B4 0.69 Pf1N1B4_2487 Biotin synthase (EC 2.8.1.6) 0.54 Pf1N1B4_2411 FIG00953568: hypothetical protein low > 87
Pseudomonas fluorescens FW300-N2E2 0.69 Pf6N2E2_4759 Biotin synthase (EC 2.8.1.6) 0.54 Pf6N2E2_4672 FIG00953568: hypothetical protein low > 103
Pseudomonas sp. S08-1 0.69 OH686_10355 biotin synthase 0.53 OH686_10655 Uncharacterized protein YhiN low > 80
Klebsiella michiganensis M5al 0.69 BWI76_RS08760 biotin synthase 0.57 BWI76_RS26565 membrane protein low > 92
Pseudomonas fluorescens FW300-N2E3 0.69 AO353_07525 biotin synthase 0.53 AO353_07855 hypothetical protein low > 101
Pseudomonas fluorescens FW300-N2C3 0.69 AO356_14135 biotin synthase 0.54 AO356_13765 hypothetical protein low > 104
Pseudomonas fluorescens SBW25-INTG 0.68 PFLU_RS27650 biotin synthase BioB 0.54 PFLU_RS28025 NAD(P)/FAD-dependent oxidoreductase low > 109
Pseudomonas fluorescens SBW25 0.68 PFLU_RS27650 biotin synthase BioB 0.54 PFLU_RS28025 NAD(P)/FAD-dependent oxidoreductase low > 109
Pseudomonas fluorescens GW456-L13 0.68 PfGW456L13_1147 Biotin synthase (EC 2.8.1.6) 0.53 PfGW456L13_1077 FIG00953568: hypothetical protein low > 87
Pseudomonas lactucae CFBP13502 0.68 GEMAOFIL_05322 Biotin synthase 0.53 GEMAOFIL_05401 hypothetical protein low > 96
Pseudomonas orientalis W4I3 0.68 QF045_RS00415 biotin synthase BioB 0.54 QF045_RS00760 NAD(P)/FAD-dependent oxidoreductase low > 93
Pseudomonas simiae WCS417 0.68 PS417_26005 biotin synthase 0.54 PS417_26375 membrane protein low > 88
Alteromonas macleodii MIT1002 0.68 MIT1002_01379 Biotin synthase 0.61 MIT1002_00118 N-methyltryptophan oxidase low > 70
Pseudomonas sp. DMC3 0.68 GFF76 Biotin synthase 0.55 GFF143 putative protein low > 89
Shewanella amazonensis SB2B 0.66 Sama_1438 biotin synthase (RefSeq) 0.60 Sama_0064 hypothetical protein (RefSeq) — —
Kangiella aquimarina DSM 16071 0.65 B158DRAFT_0864 biotin synthase (EC 2.8.1.6) 0.54 B158DRAFT_1203 flavoprotein, HI0933 family — —
Shewanella oneidensis MR-1 0.65 SO2740 bioB biotin synthase (NCBI ptt file) 0.61 SO0054 conserved hypothetical protein TIGR00275 (NCBI ptt file) — —
Marinobacter adhaerens HP15 0.65 HP15_2486 biotin synthase 0.52 HP15_1033 flavoprotein, NADB Rossmann superfamily low > 73
Shewanella sp. ANA-3 0.65 Shewana3_2519 biotin synthase (RefSeq) 0.62 Shewana3_0055 hypothetical protein (RefSeq) low > 73
Shewanella loihica PV-4 0.63 Shew_1719 biotin synthase (RefSeq) 0.61 Shew_3802 hypothetical protein (RefSeq) — —
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS01085 biotin synthase BioB 0.44 QEN71_RS15210 NAD(P)/FAD-dependent oxidoreductase — —
Acinetobacter baumannii LAC-4 0.59 RR41_RS11800 biotin synthase BioB 0.48 RR41_RS15405 NAD(P)/FAD-dependent oxidoreductase — —
Ralstonia solanacearum PSI07 0.59 RPSI07_RS22850 biotin synthase BioB 0.45 RPSI07_RS13540 NAD(P)/FAD-dependent oxidoreductase low > 81
Ralstonia solanacearum GMI1000 0.59 RS_RS01305 biotin synthase 0.44 RS_RS11135 NAD(P)/FAD-dependent oxidoreductase low > 80
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS06265 biotin synthase BioB 0.45 ABZR87_RS15620 NAD(P)/FAD-dependent oxidoreductase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_02097 biotin synthase 0.43 H281DRAFT_06012 hypothetical protein low > 103
Burkholderia phytofirmans PsJN 0.59 BPHYT_RS02150 biotin synthase 0.43 BPHYT_RS33560 membrane protein low > 109
Acinetobacter radioresistens SK82 0.59 MPMX26_01785 Biotin synthase 0.46 MPMX26_02534 hypothetical protein low > 36
Paraburkholderia graminis OAS925 0.58 ABIE53_000577 biotin synthase 0.43 ABIE53_004862 putative Rossmann fold flavoprotein low > 113
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS10465 biotin synthase BioB 0.44 RALBFv3_RS03690 NAD(P)/FAD-dependent oxidoreductase low > 76
Ralstonia solanacearum UW163 0.58 UW163_RS03115 biotin synthase BioB 0.44 UW163_RS09980 NAD(P)/FAD-dependent oxidoreductase — —
Lysobacter sp. OAE881 0.58 ABIE51_RS01140 biotin synthase BioB 0.52 ABIE51_RS09810 NAD(P)/FAD-dependent oxidoreductase low > 62
Dyella japonica UNC79MFTsu3.2 0.57 ABZR86_RS15840 biotin synthase BioB 0.54 ABZR86_RS00415 NAD(P)/FAD-dependent oxidoreductase low > 74
Magnetospirillum magneticum AMB-1 0.57 AMB_RS13865 biotin synthase 0.50 AMB_RS17480 NAD(P)/FAD-dependent oxidoreductase — —
Agrobacterium fabrum C58 0.56 Atu3997 biotin synthetase 0.49 Atu0603 hypothetical protein low > 89
Cupriavidus basilensis FW507-4G11 0.56 RR42_RS00940 biotin synthase 0.45 RR42_RS14990 membrane protein low > 128
Sphingomonas koreensis DSMZ 15582 0.56 Ga0059261_3989 biotin synthase (EC 2.8.1.6) 0.48 Ga0059261_3388 flavoprotein, HI0933 family low > 68
Variovorax sp. SCN45 0.56 GFF937 Biotin synthase (EC 2.8.1.6) 0.47 GFF4713 Uncharacterized protein YhiN low > 127
Castellaniella sp019104865 MT123 0.56 ABCV34_RS15280 biotin synthase BioB 0.40 ABCV34_RS08895 NAD(P)/FAD-dependent oxidoreductase low > 48
Acidovorax sp. GW101-3H11 0.55 Ac3H11_2272 Biotin synthase (EC 2.8.1.6) 0.45 Ac3H11_3253 NAD(FAD)-utilizing dehydrogenases low > 79
Xanthomonas campestris pv. campestris strain 8004 0.55 Xcc-8004.505.1 Biotin synthase (EC 2.8.1.6) 0.52 Xcc-8004.2264.1 FIG01211838: hypothetical protein low > 74
Herbaspirillum seropedicae SmR1 0.55 HSERO_RS12235 biotin synthase 0.46 HSERO_RS04345 membrane protein low > 78
Rhodanobacter sp. FW510-T8 0.55 OKGIIK_13650 bioB biotin synthase BioB 0.54 OKGIIK_03505 yhiN NAD(P)/FAD-dependent oxidoreductase low > 53
Variovorax sp. OAS795 0.54 ABID97_RS13955 biotin synthase BioB 0.43 ABID97_RS20650 NAD(P)/FAD-dependent oxidoreductase low > 91
Caulobacter crescentus NA1000 0.54 CCNA_03636 biotin synthase 0.51 CCNA_01545 NAD(FAD)-utilizing dehydrogenase low > 66
Caulobacter crescentus NA1000 Δfur 0.54 CCNA_03636 biotin synthase 0.51 CCNA_01545 NAD(FAD)-utilizing dehydrogenase low > 67
Rhodanobacter denitrificans FW104-10B01 0.54 LRK54_RS10260 biotin synthase BioB 0.53 LRK54_RS14680 NAD(P)/FAD-dependent oxidoreductase low > 59
Rhodanobacter denitrificans MT42 0.54 LRK55_RS09900 biotin synthase BioB 0.54 LRK55_RS14395 NAD(P)/FAD-dependent oxidoreductase low > 63
Hydrogenophaga sp. GW460-11-11-14-LB1 0.54 GFF3992 Biotin synthase (EC 2.8.1.6) 0.46 GFF3659 NAD(FAD)-utilizing dehydrogenases — —
Phaeobacter inhibens DSM 17395 0.54 PGA1_c09120 biotin synthase BioB 0.48 PGA1_c09590 uncharacterized protein YhiN low > 62
Sphingobium sp. HT1-2 0.53 GFF133 Biotin synthase (EC 2.8.1.6) 0.44 GFF1279 Uncharacterized protein YhiN low > 95
Rhodopseudomonas palustris CGA009 0.53 TX73_010535 biotin synthase BioB 0.10 TX73_011285 NAD(P)/FAD-dependent oxidoreductase low > 86
Echinicola vietnamensis KMM 6221, DSM 17526 0.53 Echvi_2566 biotin synthetase 0.17 Echvi_3335 flavoprotein, HI0933 family low > 79
Rhizobium sp. OAE497 0.52 ABIE40_RS21075 biotin synthase BioB 0.52 ABIE40_RS03215 NAD(P)/FAD-dependent oxidoreductase low > 107
Synechococcus elongatus PCC 7942 0.51 Synpcc7942_0419 bioB biotin synthase 0.18 Synpcc7942_2067 hypothetical protein — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.51 CA264_02425 biotin synthase BioB 0.17 CA264_05900 aminoacetone oxidase family FAD-binding enzyme low > 74
Cellulophaga baltica 18 0.50 M666_RS03345 biotin synthase BioB 0.14 M666_RS02740 NAD(P)/FAD-dependent oxidoreductase — —
Pedobacter sp. GW460-11-11-14-LB5 0.50 CA265_RS09475 biotin synthase BioB 0.40 CA265_RS07750 aminoacetone oxidase family FAD-binding enzyme low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.47 ABZR88_RS10190 biotin synthase BioB 0.40 ABZR88_RS09315 NAD(P)/FAD-dependent oxidoreductase low > 71
Synechocystis sp000284455 PCC 6803 0.26 SGL_RS07055 biotin synthase BioB 0.16 SGL_RS15645 NAD(P)/FAD-dependent oxidoreductase — —
Desulfovibrio vulgaris Hildenborough JW710 0.24 DVU2558 bioB biotin synthase (Dmitry Rodionov) 0.38 DVU2234 conserved hypothetical protein TIGR00275 (TIGR) low > 55
Desulfovibrio vulgaris Miyazaki F 0.20 DvMF_1001 biotin synthase (RefSeq) 0.40 DvMF_0830 HI0933 family protein (RefSeq) low > 51

Not shown: 11 genomes with orthologs for CSW01_05645 only; 5 genomes with orthologs for CSW01_00430 only