Conservation of cofitness between BWI76_RS20965 and BWI76_RS07065 in Klebsiella michiganensis M5al

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20965 phosphoribosylformylglycinamidine cyclo-ligase 1.0 BWI76_RS07065 5-(carboxyamino)imidazole ribonucleotide synthase 0.86 6
Enterobacter asburiae PDN3 0.95 EX28DRAFT_0168 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.89 EX28DRAFT_2460 phosphoribosylaminoimidazole carboxylase, PurK protein — —
Enterobacter sp. TBS_079 0.95 MPMX20_03354 Phosphoribosylformylglycinamidine cyclo-ligase 0.87 MPMX20_01097 N5-carboxyaminoimidazole ribonucleotide synthase 0.95 4
Escherichia coli Nissle 1917 0.94 ECOLIN_RS14190 phosphoribosylformylglycinamidine cyclo-ligase 0.87 ECOLIN_RS03025 5-(carboxyamino)imidazole ribonucleotide synthase 0.67 25
Escherichia coli BL21 0.94 ECD_02391 phosphoribosylaminoimidazole synthetase 0.87 ECD_00472 N5-carboxyaminoimidazole ribonucleotide synthase 0.90 6
Escherichia coli HS(pFamp)R (ATCC 700891) 0.94 OHPLBJKB_01227 Phosphoribosylformylglycinamidine cyclo-ligase 0.86 OHPLBJKB_03159 N5-carboxyaminoimidazole ribonucleotide synthase low > 73
Escherichia coli BW25113 0.94 b2499 purM phosphoribosylaminoimidazole synthetase (NCBI) 0.86 b0522 purK phosphoribosylaminoimidazole carboxylase (NCBI) 0.94 6
Escherichia fergusonii Becca 0.93 EFB2_01399 Phosphoribosylformylglycinamidine cyclo-ligase 0.87 EFB2_03540 N5-carboxyaminoimidazole ribonucleotide synthase low > 86
Escherichia coli ECOR27 0.93 NOLOHH_13460 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.86 NOLOHH_00830 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.91 7
Rahnella sp. WP5 0.93 EX31_RS22695 phosphoribosylformylglycinamidine cyclo-ligase 0.79 EX31_RS22620 5-(carboxyamino)imidazole ribonucleotide synthase 0.94 5
Escherichia coli ECRC62 0.93 BNILDI_12270 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.86 BNILDI_22260 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.93 17
Escherichia coli ECOR38 0.93 HEPCGN_20975 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.87 HEPCGN_06480 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.95 9
Escherichia coli ECRC99 0.93 KEDOAH_06410 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.86 KEDOAH_20130 purK 5-(carboxyamino)imidazole ribonucleotide synthase — —
Escherichia coli ECRC100 0.93 OKFHMN_21810 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.86 OKFHMN_07840 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.96 4
Escherichia coli ECRC98 0.93 JDDGAC_25755 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.86 JDDGAC_11490 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.83 2
Escherichia coli ECRC101 0.93 MCAODC_12340 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.86 MCAODC_27060 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.89 7
Escherichia coli ECRC102 0.93 NIAGMN_19580 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.86 NIAGMN_05895 purK 5-(carboxyamino)imidazole ribonucleotide synthase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2169 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.88 GFF4438 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) low > 78
Pectobacterium carotovorum WPP14 0.89 HER17_RS15465 phosphoribosylformylglycinamidine cyclo-ligase 0.78 HER17_RS06470 5-(carboxyamino)imidazole ribonucleotide synthase 0.91 44
Serratia liquefaciens MT49 0.88 IAI46_18885 phosphoribosylformylglycinamidine cyclo-ligase 0.76 IAI46_05370 5-(carboxyamino)imidazole ribonucleotide synthase 0.48 43
Pantoea sp. MT58 0.88 IAI47_05180 phosphoribosylformylglycinamidine cyclo-ligase 0.80 IAI47_14355 5-(carboxyamino)imidazole ribonucleotide synthase 0.97 11
Erwinia tracheiphila SCR3 0.88 LU632_RS08275 purM phosphoribosylformylglycinamidine cyclo-ligase 0.75 LU632_RS15250 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.88 12
Dickeya dadantii 3937 0.87 DDA3937_RS06025 phosphoribosylformylglycinamidine cyclo-ligase 0.78 DDA3937_RS15110 5-(carboxyamino)imidazole ribonucleotide synthase 0.86 11
Dickeya dianthicola ME23 0.87 DZA65_RS06420 phosphoribosylformylglycinamidine cyclo-ligase 0.78 DZA65_RS15995 5-(carboxyamino)imidazole ribonucleotide synthase 0.88 6
Dickeya dianthicola 67-19 0.87 HGI48_RS06070 phosphoribosylformylglycinamidine cyclo-ligase 0.78 HGI48_RS15190 5-(carboxyamino)imidazole ribonucleotide synthase 0.74 16
Shewanella amazonensis SB2B 0.78 Sama_2097 phosphoribosylaminoimidazole synthetase (RefSeq) 0.51 Sama_1063 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.95 5
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_11350 phosphoribosylformylglycinamidine cyclo-ligase 0.31 CSW01_00260 5-(carboxyamino)imidazole ribonucleotide synthase low > 62
Shewanella sp. ANA-3 0.76 Shewana3_2545 phosphoribosylaminoimidazole synthetase (RefSeq) 0.50 Shewana3_3156 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.93 8
Shewanella oneidensis MR-1 0.76 SO2760 purM phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) 0.49 SO3555 purK phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI ptt file) 0.96 3
Shewanella loihica PV-4 0.74 Shew_1513 phosphoribosylaminoimidazole synthetase (RefSeq) 0.26 Shew_1249 phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) — —
Alteromonas macleodii MIT1002 0.73 MIT1002_02219 Phosphoribosylformylglycinamidine cyclo-ligase 0.33 MIT1002_00522 N5-carboxyaminoimidazole ribonucleotide synthase 0.98 16
Kangiella aquimarina DSM 16071 0.71 B158DRAFT_2385 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.28 B158DRAFT_0610 5-(carboxyamino)imidazole ribonucleotide synthase — —
Pseudomonas stutzeri RCH2 0.70 Psest_1474 phosphoribosylaminoimidazole synthetase 0.28 Psest_4068 phosphoribosylaminoimidazole carboxylase, PurK protein — —
Pseudomonas syringae pv. syringae B728a 0.70 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase 0.27 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.70 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase 0.27 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase — —
Pseudomonas fluorescens SBW25 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase 0.28 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase — —
Pseudomonas fluorescens SBW25-INTG 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase 0.28 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase — —
Pseudomonas sp. RS175 0.69 PFR28_03217 Phosphoribosylformylglycinamidine cyclo-ligase 0.28 PFR28_04495 N5-carboxyaminoimidazole ribonucleotide synthase — —
Pseudomonas fluorescens FW300-N2C3 0.69 AO356_19090 phosphoribosylaminoimidazole synthetase 0.28 AO356_11075 phosphoribosylaminoimidazole carboxylase — —
Pseudomonas simiae WCS417 0.69 PS417_20120 phosphoribosylaminoimidazole synthetase 0.28 PS417_28115 phosphoribosylaminoimidazole carboxylase — —
Pseudomonas fluorescens FW300-N2E2 0.69 Pf6N2E2_5729 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.28 Pf6N2E2_4081 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) — —
Pseudomonas putida KT2440 0.69 PP_1665 Phosphoribosylformylglycinamidine cyclo-ligase 0.28 PP_5335 N5-carboxyaminoimidazole ribonucleotide synthase — —
Pseudomonas fluorescens FW300-N2E3 0.69 AO353_02680 phosphoribosylaminoimidazole synthetase 0.28 AO353_09935 phosphoribosylaminoimidazole carboxylase — —
Pseudomonas fluorescens GW456-L13 0.69 PfGW456L13_4252 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.28 PfGW456L13_747 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) — —
Pseudomonas fluorescens FW300-N1B4 0.69 Pf1N1B4_3698 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.28 Pf1N1B4_2028 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) — —
Pseudomonas sp. S08-1 0.69 OH686_18995 Phosphoribosylformylglycinamidine cyclo-ligase 0.28 OH686_13380 N5-carboxyaminoimidazole ribonucleotide synthase — —
Acinetobacter radioresistens SK82 0.68 MPMX26_02206 Phosphoribosylformylglycinamidine cyclo-ligase 0.29 MPMX26_03050 N5-carboxyaminoimidazole ribonucleotide synthase 0.88 13
Marinobacter adhaerens HP15 0.67 HP15_1299 phosphoribosylaminoimidazole synthetase 0.30 HP15_2350 phosphoribosylaminoimidazole carboxylase ATPase subunit — —
Dechlorosoma suillum PS 0.63 Dsui_1519 phosphoribosylaminoimidazole synthetase 0.20 Dsui_0091 phosphoribosylaminoimidazole carboxylase, PurK protein — —
Cupriavidus basilensis FW507-4G11 0.61 RR42_RS17220 phosphoribosylaminoimidazole synthetase 0.19 RR42_RS03230 phosphoribosylaminoimidazole carboxylase — —
Castellaniella sp019104865 MT123 0.58 ABCV34_RS08795 phosphoribosylformylglycinamidine cyclo-ligase 0.20 ABCV34_RS00565 5-(carboxyamino)imidazole ribonucleotide synthase — —
Ralstonia solanacearum PSI07 0.57 RPSI07_RS12020 phosphoribosylformylglycinamidine cyclo-ligase 0.18 RPSI07_RS21130 5-(carboxyamino)imidazole ribonucleotide synthase — —
Ralstonia sp. UNC404CL21Col 0.57 ABZR87_RS00915 phosphoribosylformylglycinamidine cyclo-ligase 0.18 ABZR87_RS08090 5-(carboxyamino)imidazole ribonucleotide synthase — —
Ralstonia solanacearum IBSBF1503 0.57 RALBFv3_RS05280 phosphoribosylformylglycinamidine cyclo-ligase 0.18 RALBFv3_RS12200 5-(carboxyamino)imidazole ribonucleotide synthase — —
Ralstonia solanacearum UW163 0.57 UW163_RS08345 phosphoribosylformylglycinamidine cyclo-ligase 0.18 UW163_RS01410 5-(carboxyamino)imidazole ribonucleotide synthase — —
Herbaspirillum seropedicae SmR1 0.57 HSERO_RS03165 phosphoribosylaminoimidazole synthetase 0.23 HSERO_RS03370 phosphoribosylaminoimidazole carboxylase — —
Rhodanobacter denitrificans MT42 0.57 LRK55_RS12645 phosphoribosylformylglycinamidine cyclo-ligase 0.25 LRK55_RS13530 5-(carboxyamino)imidazole ribonucleotide synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.57 LRK54_RS12945 phosphoribosylformylglycinamidine cyclo-ligase 0.25 LRK54_RS13815 5-(carboxyamino)imidazole ribonucleotide synthase — —
Rhodospirillum rubrum S1H 0.57 Rru_A2167 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) 0.20 Rru_A1051 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) low > 58
Ralstonia solanacearum GMI1000 0.57 RS_RS13145 phosphoribosylformylglycinamidine cyclo-ligase 0.19 RS_RS02885 5-(carboxyamino)imidazole ribonucleotide synthase — —
Paraburkholderia sabiae LMG 24235 0.56 QEN71_RS26445 phosphoribosylformylglycinamidine cyclo-ligase 0.20 QEN71_RS02450 5-(carboxyamino)imidazole ribonucleotide synthase 0.61 99
Variovorax sp. OAS795 0.56 ABID97_RS08700 phosphoribosylformylglycinamidine cyclo-ligase 0.23 ABID97_RS01700 5-(carboxyamino)imidazole ribonucleotide synthase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.56 GFF3433 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.26 GFF2770 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) — —
Variovorax sp. SCN45 0.56 GFF3941 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.25 GFF5513 N5-carboxyaminoimidazole ribonucleotide synthase (EC 6.3.4.18) 0.94 2
Burkholderia phytofirmans PsJN 0.55 BPHYT_RS03640 phosphoribosylformylglycinamidine cyclo-ligase 0.22 BPHYT_RS16245 phosphoribosylaminoimidazole carboxylase 0.82 5
Azospirillum brasilense Sp245 0.55 AZOBR_RS16290 phosphoribosylaminoimidazole synthetase 0.24 AZOBR_RS06140 phosphoribosylaminoimidazole carboxylase — —
Acidovorax sp. GW101-3H11 0.55 Ac3H11_1318 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.22 Ac3H11_675 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) — —
Paraburkholderia bryophila 376MFSha3.1 0.55 H281DRAFT_04710 phosphoribosylformylglycinamidine cyclo-ligase 0.21 H281DRAFT_04185 5-(carboxyamino)imidazole ribonucleotide synthase — —
Paraburkholderia graminis OAS925 0.55 ABIE53_000874 phosphoribosylformylglycinamidine cyclo-ligase 0.22 ABIE53_003423 5-(carboxyamino)imidazole ribonucleotide synthase — —
Lysobacter sp. OAE881 0.55 ABIE51_RS15890 phosphoribosylformylglycinamidine cyclo-ligase 0.25 ABIE51_RS15390 5-(carboxyamino)imidazole ribonucleotide synthase low > 62
Xanthomonas campestris pv. campestris strain 8004 0.55 Xcc-8004.1676.1 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.26 Xcc-8004.2012.1 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.89 4
Azospirillum sp. SherDot2 0.54 MPMX19_01304 Phosphoribosylformylglycinamidine cyclo-ligase 0.24 MPMX19_01418 N5-carboxyaminoimidazole ribonucleotide synthase — —
Dyella japonica UNC79MFTsu3.2 0.54 ABZR86_RS19865 phosphoribosylformylglycinamidine cyclo-ligase 0.23 ABZR86_RS09830 5-(carboxyamino)imidazole ribonucleotide synthase — —
Agrobacterium fabrum C58 0.54 Atu1141 Phosphoribosylglycinamide synthetase 0.24 Atu3755 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.94 5
Phaeobacter inhibens DSM 17395 0.54 PGA1_c13260 phosphoribosylformylglycinamidine cyclo-ligase PurM 0.27 PGA1_c24870 phosphoribosylaminoimidazole carboxylase ATPase subunit PurK 0.91 4
Rhodanobacter sp. FW510-T8 0.53 OKGIIK_02315 purM phosphoribosylformylglycinamidine cyclo-ligase 0.26 OKGIIK_03050 purK 5-(carboxyamino)imidazole ribonucleotide synthase — —
Magnetospirillum magneticum AMB-1 0.53 AMB_RS14330 phosphoribosylformylglycinamidine cyclo-ligase 0.22 AMB_RS11140 5-(carboxyamino)imidazole ribonucleotide synthase — —
Synechococcus elongatus PCC 7942 0.53 Synpcc7942_0851 purM phosphoribosylaminoimidazole synthetase 0.20 Synpcc7942_1428 purK phosphoribosylaminoimidazole carboxylase ATPase subunit — —
Rhizobium sp. OAE497 0.53 ABIE40_RS06560 phosphoribosylformylglycinamidine cyclo-ligase 0.24 ABIE40_RS16070 5-(carboxyamino)imidazole ribonucleotide synthase 0.86 52
Sinorhizobium meliloti 1021 0.52 SMc00615 phosphoribosylaminoimidazole synthetase 0.26 SMc04002 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.95 15
Sphingomonas koreensis DSMZ 15582 0.51 Ga0059261_0228 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.23 Ga0059261_1428 5-(carboxyamino)imidazole ribonucleotide synthase — —
Caulobacter crescentus NA1000 Δfur 0.50 CCNA_01775 phosphoribosylformylglycinamidine cyclo-ligase 0.26 CCNA_03392 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit low > 67
Caulobacter crescentus NA1000 0.50 CCNA_01775 phosphoribosylformylglycinamidine cyclo-ligase 0.26 CCNA_03392 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit 0.87 13
Dinoroseobacter shibae DFL-12 0.50 Dshi_1889 phosphoribosylformylglycinamidine cyclo-ligase (RefSeq) 0.26 Dshi_0680 phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) 0.89 6
Brevundimonas sp. GW460-12-10-14-LB2 0.50 A4249_RS08210 phosphoribosylformylglycinamidine cyclo-ligase 0.23 A4249_RS08935 5-(carboxyamino)imidazole ribonucleotide synthase — —
Rhodopseudomonas palustris CGA009 0.49 TX73_015785 phosphoribosylformylglycinamidine cyclo-ligase 0.26 TX73_021645 5-(carboxyamino)imidazole ribonucleotide synthase — —
Bosea sp. OAE506 0.49 ABIE41_RS17040 phosphoribosylformylglycinamidine cyclo-ligase 0.22 ABIE41_RS09245 5-(carboxyamino)imidazole ribonucleotide synthase low > 77
Bifidobacterium breve UCC2003 0.47 BBR_RS13375 phosphoribosylformylglycinamidine cyclo-ligase 0.20 BBR_RS13300 5-(carboxyamino)imidazole ribonucleotide synthase low > 34
Mycobacterium tuberculosis H37Rv 0.39 Rv0809 Probable phosphoribosylformylglycinamidine CYCLO-ligase PurM (AIRS) (phosphoribosyl-aminoimidazole synthetase) (air synthase) 0.21 Rv3276c Probable phosphoribosylaminoimidazole carboxylase ATPase subunit PurK (air carboxylase) (AIRC) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.09 ABZR88_RS04080 AIR synthase related protein 0.17 ABZR88_RS09290 5-(carboxyamino)imidazole ribonucleotide synthase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.08 Echvi_0734 Phosphoribosylaminoimidazole (AIR) synthetase 0.18 Echvi_0884 phosphoribosylaminoimidazole carboxylase, PurK protein — —

Not shown: 11 genomes with orthologs for BWI76_RS20965 only; 2 genomes with orthologs for BWI76_RS07065 only