Conservation of cofitness between BWI76_RS27390 and BWI76_RS01615 in Klebsiella michiganensis M5al

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS27390 ribonuclease PH 1.0 BWI76_RS01615 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.71 6
Enterobacter sp. TBS_079 0.94 MPMX20_00092 Ribonuclease PH 0.96 MPMX20_00226 Bifunctional purine biosynthesis protein PurH low > 85
Enterobacter asburiae PDN3 0.93 EX28DRAFT_3893 ribonuclease PH 0.96 EX28DRAFT_4545 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF366 Ribonuclease PH (EC 2.7.7.56) 0.97 GFF4186 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 78
Escherichia coli BL21 0.92 ECD_03500 ribonuclease PH 0.94 ECD_03883 IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_00059 Ribonuclease PH 0.94 OHPLBJKB_04043 Bifunctional purine biosynthesis protein PurH low > 73
Escherichia coli ECRC62 0.92 BNILDI_04045 rph ribonuclease PH 0.94 BNILDI_06065 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Escherichia coli ECRC99 0.92 KEDOAH_12555 rph ribonuclease PH 0.94 KEDOAH_14850 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECOR27 0.92 NOLOHH_07470 rph ribonuclease PH 0.94 NOLOHH_05455 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.76 19
Escherichia coli Nissle 1917 0.92 ECOLIN_RS20755 ribonuclease PH 0.94 ECOLIN_RS23100 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.36 40
Escherichia coli ECRC101 0.92 MCAODC_06100 rph ribonuclease PH 0.94 MCAODC_03810 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 87
Escherichia coli ECRC98 0.92 JDDGAC_19215 rph ribonuclease PH 0.94 JDDGAC_16935 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 86
Escherichia coli ECRC102 0.92 NIAGMN_13350 rph ribonuclease PH 0.94 NIAGMN_11060 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECRC100 0.92 OKFHMN_15590 rph ribonuclease PH 0.94 OKFHMN_13310 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.80 30
Escherichia coli ECOR38 0.92 HEPCGN_14410 rph ribonuclease PH 0.94 HEPCGN_11950 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 87
Escherichia fergusonii Becca 0.92 EFB2_00170 Ribonuclease PH 0.94 EFB2_04604 Bifunctional purine biosynthesis protein PurH low > 86
Dickeya dadantii 3937 0.89 DDA3937_RS20540 ribonuclease PH 0.91 DDA3937_RS01220 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 74
Dickeya dianthicola 67-19 0.89 HGI48_RS00675 ribonuclease PH 0.90 HGI48_RS01215 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 71
Dickeya dianthicola ME23 0.89 DZA65_RS00730 ribonuclease PH 0.90 DZA65_RS01260 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Pantoea sp. MT58 0.89 IAI47_00595 ribonuclease PH 0.90 IAI47_18040 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.66 9
Erwinia tracheiphila SCR3 0.88 LU632_RS22020 rph ribonuclease PH 0.89 LU632_RS01020 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 74
Serratia liquefaciens MT49 0.87 IAI46_24850 ribonuclease PH 0.89 IAI46_01365 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 86
Escherichia coli BW25113 0.87 b3643 rph ribonuclease PH (NCBI) 0.94 b4006 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) low > 76
Rahnella sp. WP5 0.87 EX31_RS14505 ribonuclease PH 0.88 EX31_RS16860 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.67 70
Pectobacterium carotovorum WPP14 0.86 HER17_RS20855 ribonuclease PH 0.90 HER17_RS20335 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Shewanella amazonensis SB2B 0.78 Sama_0320 tRNA nucleotidyltransferase (RefSeq) 0.76 Sama_0395 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 62
Shewanella loihica PV-4 0.78 Shew_3488 ribonuclease PH (RefSeq) 0.77 Shew_3412 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.77 SO4256 rph ribonuclease PH (NCBI ptt file) 0.73 SO0442 purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.77 Shewana3_3777 RNAse PH (RefSeq) 0.74 Shewana3_0441 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 73
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_01115 ribonuclease PH 0.80 CSW01_01420 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase low > 62
Alteromonas macleodii MIT1002 0.75 MIT1002_04071 Ribonuclease PH 0.75 MIT1002_03959 Bifunctional purine biosynthesis protein PurH — —
Marinobacter adhaerens HP15 0.70 HP15_300 ribonuclease PH 0.71 HP15_3227 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas sp. S08-1 0.70 OH686_13570 ribonuclease PH 0.69 OH686_07620 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Kangiella aquimarina DSM 16071 0.70 B158DRAFT_0588 ribonuclease PH 0.70 B158DRAFT_0166 IMP cyclohydrolase (EC 3.5.4.10)/phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas stutzeri RCH2 0.69 Psest_3813 ribonuclease PH 0.68 Psest_1014 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_0213 RNAse PH 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_0213 RNAse PH 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens FW300-N2E2 0.68 Pf6N2E2_4365 Ribonuclease PH (EC 2.7.7.56) 0.68 Pf6N2E2_3519 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas fluorescens FW300-N1B4 0.68 Pf1N1B4_2117 Ribonuclease PH (EC 2.7.7.56) 0.68 Pf1N1B4_1315 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 87
Pseudomonas putida KT2440 0.68 PP_5294 Ribonuclease PH 0.68 PP_4822 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas fluorescens GW456-L13 0.68 PfGW456L13_784 Ribonuclease PH (EC 2.7.7.56) 0.68 PfGW456L13_57 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas fluorescens FW300-N2C3 0.68 AO356_12500 ribonuclease PH 0.68 AO356_08225 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Dechlorosoma suillum PS 0.68 Dsui_0494 ribonuclease PH 0.54 Dsui_1595 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas fluorescens FW300-N2E3 0.68 AO353_09260 ribonuclease PH 0.68 AO353_13650 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas sp. RS175 0.68 PFR28_04420 Ribonuclease PH 0.68 PFR28_05214 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas simiae WCS417 0.68 PS417_27810 ribonuclease PH 0.68 PS417_02940 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.68 PFLU_RS29490 ribonuclease PH 0.68 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Pseudomonas fluorescens SBW25 0.68 PFLU_RS29490 ribonuclease PH 0.68 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH low > 109
Xanthomonas campestris pv. campestris strain 8004 0.67 Xcc-8004.1221.1 Ribonuclease PH (EC 2.7.7.56) 0.57 Xcc-8004.659.1 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 74
Acinetobacter radioresistens SK82 0.67 MPMX26_00040 Ribonuclease PH 0.70 MPMX26_01141 Bifunctional purine biosynthesis protein PurH low > 36
Variovorax sp. SCN45 0.67 GFF2381 Ribonuclease PH (EC 2.7.7.56) 0.56 GFF2146 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.66 GFF3254 Ribonuclease PH (EC 2.7.7.56) 0.57 GFF636 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Paraburkholderia sabiae LMG 24235 0.65 QEN71_RS03645 ribonuclease PH 0.59 QEN71_RS26780 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.65 H281DRAFT_04008 RNAse PH 0.60 H281DRAFT_04251 IMP cyclohydrolase /phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Paraburkholderia graminis OAS925 0.65 ABIE53_003234 ribonuclease PH 0.60 ABIE53_003491 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS15255 ribonuclease PH 0.59 ABZR87_RS07640 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Burkholderia phytofirmans PsJN 0.65 BPHYT_RS15325 ribonuclease PH 0.60 BPHYT_RS16595 bifunctional purine biosynthesis protein PurH — —
Variovorax sp. OAS795 0.64 ABID97_RS23640 ribonuclease PH 0.56 ABID97_RS24725 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Ralstonia solanacearum PSI07 0.64 RPSI07_RS13840 ribonuclease PH 0.59 RPSI07_RS21530 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Ralstonia solanacearum GMI1000 0.64 RS_RS10830 ribonuclease PH 0.59 RS_RS02505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase — —
Herbaspirillum seropedicae SmR1 0.64 HSERO_RS10655 ribonuclease PH 0.58 HSERO_RS02060 purine biosynthesis protein purH — —
Dyella japonica UNC79MFTsu3.2 0.64 ABZR86_RS11900 ribonuclease PH 0.61 ABZR86_RS17045 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Ralstonia solanacearum UW163 0.63 UW163_RS10375 ribonuclease PH 0.59 UW163_RS01900 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS03345 ribonuclease PH 0.59 RALBFv3_RS11685 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Cupriavidus basilensis FW507-4G11 0.63 RR42_RS04890 ribonuclease PH 0.59 RR42_RS02720 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Lysobacter sp. OAE881 0.62 ABIE51_RS17285 ribonuclease PH 0.57 ABIE51_RS17760 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 62
Azospirillum brasilense Sp245 0.62 AZOBR_RS02205 ribonuclease PH 0.51 AZOBR_RS00225 purine biosynthesis protein purH — —
Acidovorax sp. GW101-3H11 0.61 Ac3H11_3670 Ribonuclease PH (EC 2.7.7.56) 0.55 Ac3H11_3994 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Castellaniella sp019104865 MT123 0.61 ABCV34_RS03515 ribonuclease PH 0.55 ABCV34_RS07970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Agrobacterium fabrum C58 0.60 Atu0327 ribonuclease PH 0.47 Atu2823 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rhodanobacter denitrificans FW104-10B01 0.60 LRK54_RS11745 ribonuclease PH 0.58 LRK54_RS06825 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rhodanobacter denitrificans MT42 0.60 LRK55_RS11470 ribonuclease PH 0.59 LRK55_RS06570 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 63
Rhodopseudomonas palustris CGA009 0.60 TX73_001710 ribonuclease PH 0.52 TX73_000145 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Bosea sp. OAE506 0.59 ABIE41_RS03295 ribonuclease PH 0.51 ABIE41_RS05095 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 77
Rhodanobacter sp. FW510-T8 0.59 OKGIIK_12150 rph ribonuclease PH 0.58 OKGIIK_16805 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Sinorhizobium meliloti 1021 0.59 SMc01144 ribonuclease PH 0.47 SMc04088 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 103
Azospirillum sp. SherDot2 0.59 MPMX19_02576 Ribonuclease PH 0.54 MPMX19_02325 Bifunctional purine biosynthesis protein PurH — —
Rhizobium sp. OAE497 0.59 ABIE40_RS01640 ribonuclease PH 0.47 ABIE40_RS19130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 107
Dinoroseobacter shibae DFL-12 0.58 Dshi_3463 ribonuclease PH (RefSeq) 0.49 Dshi_0358 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) — —
Magnetospirillum magneticum AMB-1 0.58 AMB_RS22760 ribonuclease PH 0.50 AMB_RS00505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Rhodospirillum rubrum S1H 0.58 Rru_A3641 Ribonuclease PH (NCBI) 0.49 Rru_A3655 Phosphoribosylaminoimidazolecarboxamideformyltransferase (NCBI) — —
Phaeobacter inhibens DSM 17395 0.57 PGA1_c35030 ribonuclease PH 0.51 PGA1_c32860 bifunctional purine biosynthesis protein PurH — —
Caulobacter crescentus NA1000 Δfur 0.55 CCNA_00151 ribonuclease PH 0.46 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 67
Caulobacter crescentus NA1000 0.55 CCNA_00151 ribonuclease PH 0.46 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 66
Brevundimonas sp. GW460-12-10-14-LB2 0.55 A4249_RS13125 ribonuclease PH 0.44 A4249_RS13150 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Mycobacterium tuberculosis H37Rv 0.55 Rv1340 Probable ribonuclease RphA (RNase PH) (tRNA nucleotidyltransferase) 0.39 Rv0957 Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC) — —
Sphingomonas koreensis DSMZ 15582 0.54 Ga0059261_2741 ribonuclease PH 0.50 Ga0059261_2242 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Bifidobacterium breve UCC2003 0.52 BBR_RS12405 ribonuclease PH 0.34 BBR_RS15690 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Synechococcus elongatus PCC 7942 0.51 Synpcc7942_1073 rph ribonuclease PH 0.42 Synpcc7942_0396 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —

Not shown: 0 genomes with orthologs for BWI76_RS27390 only; 11 genomes with orthologs for BWI76_RS01615 only