Conservation of cofitness between BPHYT_RS13220 and BPHYT_RS33915 in Burkholderia phytofirmans PsJN

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS13220 phosphomethylpyrimidine synthase 1.0 BPHYT_RS33915 isopropylmalate isomerase 0.73 3
Paraburkholderia graminis OAS925 0.99 ABIE53_002857 phosphomethylpyrimidine synthase 0.96 ABIE53_004801 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit 0.77 2
Paraburkholderia bryophila 376MFSha3.1 0.98 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.97 H281DRAFT_06075 3-isopropylmalate dehydratase, large subunit 0.38 103
Paraburkholderia sabiae LMG 24235 0.95 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.95 QEN71_RS17605 3-isopropylmalate dehydratase large subunit 0.63 116
Herbaspirillum seropedicae SmR1 0.85 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.80 HSERO_RS16515 isopropylmalate isomerase 0.33 62
Dechlorosoma suillum PS 0.85 Dsui_0422 thiamine biosynthesis protein ThiC 0.70 Dsui_3201 3-isopropylmalate dehydratase, large subunit
Castellaniella sp019104865 MT123 0.78 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.77 ABCV34_RS04290 3-isopropylmalate dehydratase large subunit low > 48
Dyella japonica UNC79MFTsu3.2 0.75 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.49 ABZR86_RS15960 3-isopropylmalate dehydratase large subunit low > 74
Marinobacter adhaerens HP15 0.75 HP15_453 thiamine biosynthesis protein thiC 0.73 HP15_1834 protein containing 3-isopropylmalate dehydratase, large subunit region domain low > 73
Pseudomonas putida KT2440 0.75 PP_4922 Phosphomethylpyrimidine synthase 0.72 PP_1985 3-isopropylmalate dehydratase large subunit 0.39 48
Rhodanobacter sp. FW510-T8 0.74 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.47 OKGIIK_13585 leuC 3-isopropylmalate dehydratase large subunit low > 52
Pseudomonas sp. S08-1 0.74 OH686_15885 phosphomethylpyrimidine synthase 0.71 OH686_04480 3-isopropylmalate dehydratase large subunit low > 80
Pseudomonas stutzeri RCH2 0.74 Psest_0477 thiamine biosynthesis protein ThiC 0.72 Psest_2591 3-isopropylmalate dehydratase, large subunit low > 67
Pseudomonas fluorescens FW300-N2E2 0.74 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.72 Pf6N2E2_63 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 103
Xanthomonas campestris pv. campestris strain 8004 0.74 Xcc-8004.1066.1 hypothetical protein 0.72 Xcc-8004.1049.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 74
Pseudomonas fluorescens FW300-N2C3 0.74 AO356_08810 thiamine biosynthesis protein ThiC 0.73 AO356_21400 isopropylmalate isomerase low > 104
Pseudomonas fluorescens FW300-N2E3 0.74 AO353_13010 thiamine biosynthesis protein ThiC 0.72 AO353_20620 isopropylmalate isomerase low > 101
Pseudomonas sp. RS175 0.74 PFR28_05091 Phosphomethylpyrimidine synthase 0.73 PFR28_02824 3-isopropylmalate dehydratase large subunit low > 88
Pseudomonas fluorescens FW300-N1B4 0.73 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.72 Pf1N1B4_15 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 87
Pseudomonas fluorescens SBW25-INTG 0.73 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.71 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.36 30
Pseudomonas fluorescens SBW25 0.73 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.71 PFLU_RS20580 3-isopropylmalate dehydratase large subunit low > 109
Pseudomonas fluorescens GW456-L13 0.73 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.72 PfGW456L13_3948 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.73 Psyr_0544 hydroxymethylpyrimidine synthase 0.72 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.52 5
Pseudomonas syringae pv. syringae B728a 0.73 Psyr_0544 hydroxymethylpyrimidine synthase 0.72 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.59 36
Pseudomonas simiae WCS417 0.73 PS417_02355 thiamine biosynthesis protein ThiC 0.72 PS417_18600 isopropylmalate isomerase low > 88
Lysobacter sp. OAE881 0.73 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.48 ABIE51_RS17575 3-isopropylmalate dehydratase large subunit low > 62
Mucilaginibacter yixingensis YX-36 DSM 26809 0.72 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.52 ABZR88_RS11595 3-isopropylmalate dehydratase large subunit
Pontibacter actiniarum KMM 6156, DSM 19842 0.72 CA264_20435 phosphomethylpyrimidine synthase ThiC 0.51 CA264_09435 3-isopropylmalate dehydratase large subunit low > 74
Acinetobacter radioresistens SK82 0.71 MPMX26_00180 Phosphomethylpyrimidine synthase 0.68 MPMX26_00345 3-isopropylmalate dehydratase large subunit low > 36
Pedobacter sp. GW460-11-11-14-LB5 0.71 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.51 CA265_RS15830 3-isopropylmalate dehydratase large subunit low > 88
Echinicola vietnamensis KMM 6221, DSM 17526 0.71 Echvi_3567 thiamine biosynthesis protein ThiC 0.49 Echvi_2059 3-isopropylmalate dehydratase, large subunit low > 79
Ralstonia solanacearum PSI07 0.69 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.87 RPSI07_RS14695 3-isopropylmalate dehydratase large subunit low > 81
Pectobacterium carotovorum WPP14 0.69 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.61 HER17_RS03075 3-isopropylmalate dehydratase large subunit 0.78 53
Shewanella loihica PV-4 0.69 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.59 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) low > 60
Ralstonia sp. UNC404CL21Col 0.68 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.87 ABZR87_RS14540 3-isopropylmalate dehydratase large subunit 0.57 42
Cupriavidus basilensis FW507-4G11 0.68 RR42_RS01290 thiamine biosynthesis protein ThiC 0.86 RR42_RS14400 isopropylmalate isomerase 0.78 16
Ralstonia solanacearum IBSBF1503 0.68 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.87 RALBFv3_RS02620 3-isopropylmalate dehydratase large subunit low > 76
Ralstonia solanacearum UW163 0.68 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.87 UW163_RS11105 3-isopropylmalate dehydratase large subunit
Shewanella amazonensis SB2B 0.68 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.58 Sama_0337 isopropylmalate isomerase large subunit (RefSeq) low > 62
Rahnella sp. WP5 0.68 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.62 EX31_RS03690 3-isopropylmalate dehydratase large subunit low > 89
Ralstonia solanacearum GMI1000 0.68 RS_RS00555 phosphomethylpyrimidine synthase 0.87 RS_RS10000 3-isopropylmalate dehydratase large subunit low > 80
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.68 GFF4198 Thiamin biosynthesis protein ThiC 0.62 GFF166 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 78
Enterobacter sp. TBS_079 0.68 MPMX20_00217 Phosphomethylpyrimidine synthase 0.61 MPMX20_00767 3-isopropylmalate dehydratase large subunit 1 low > 85
Serratia liquefaciens MT49 0.67 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.59 IAI46_03345 3-isopropylmalate dehydratase large subunit low > 86
Enterobacter asburiae PDN3 0.67 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.62 EX28DRAFT_3668 3-isopropylmalate dehydratase, large subunit low > 76
Escherichia coli Nissle 1917 0.67 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.62 ECOLIN_RS00390 3-isopropylmalate dehydratase large subunit 0.58 32
Escherichia coli ECOR27 0.67 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.62 NOLOHH_03070 leuC1 3-isopropylmalate dehydratase large subunit 1 low > 75
Kangiella aquimarina DSM 16071 0.67 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.73 B158DRAFT_1319 3-isopropylmalate dehydratase, large subunit low > 40
Escherichia fergusonii Becca 0.67 EFB2_04617 Phosphomethylpyrimidine synthase 0.62 EFB2_03973 3-isopropylmalate dehydratase large subunit low > 86
Escherichia coli ECRC99 0.67 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.61 KEDOAH_17430 leuC1 3-isopropylmalate dehydratase large subunit 1
Escherichia coli ECRC102 0.67 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.61 NIAGMN_08575 leuC1 3-isopropylmalate dehydratase large subunit 1
Escherichia coli BW25113 0.67 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.62 b0072 leuC isopropylmalate isomerase large subunit (NCBI) low > 76
Escherichia coli ECRC98 0.67 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.61 JDDGAC_14320 leuC1 3-isopropylmalate dehydratase large subunit 1 low > 86
Escherichia coli ECRC62 0.67 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.62 BNILDI_08540 leuC1 3-isopropylmalate dehydratase large subunit 1 low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.67 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.62 OHPLBJKB_03585 3-isopropylmalate dehydratase large subunit low > 73
Escherichia coli ECRC100 0.67 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.61 OKFHMN_10725 leuC1 3-isopropylmalate dehydratase large subunit 1 low > 80
Escherichia coli ECRC101 0.67 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.61 MCAODC_01240 leuC1 3-isopropylmalate dehydratase large subunit 1 low > 87
Escherichia coli BL21 0.67 ECD_03871 phosphomethylpyrimidine synthase 0.62 ECD_00074 3-isopropylmalate dehydratase large subunit 0.57 24
Escherichia coli ECOR38 0.67 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.62 HEPCGN_08705 leuC1 3-isopropylmalate dehydratase large subunit 1 0.71 61
Dickeya dadantii 3937 0.67 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.61 DDA3937_RS18125 3-isopropylmalate dehydratase large subunit low > 74
Klebsiella michiganensis M5al 0.67 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.61 BWI76_RS04670 3-isopropylmalate dehydratase large subunit 0.36 62
Pantoea sp. MT58 0.67 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.62 IAI47_16010 3-isopropylmalate dehydratase large subunit low > 76
Variovorax sp. SCN45 0.67 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.75 GFF3890 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 127
Erwinia tracheiphila SCR3 0.67 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.58 LU632_RS02870 leuC 3-isopropylmalate dehydratase large subunit low > 74
Shewanella oneidensis MR-1 0.67 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.59 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) low > 76
Vibrio cholerae E7946 ATCC 55056 0.66 CSW01_00335 phosphomethylpyrimidine synthase 0.59 CSW01_12605 3-isopropylmalate dehydratase large subunit low > 62
Alteromonas macleodii MIT1002 0.66 MIT1002_00097 Phosphomethylpyrimidine synthase 0.57 MIT1002_00947 3-isopropylmalate dehydratase large subunit low > 70
Shewanella sp. ANA-3 0.66 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.59 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) low > 73
Dickeya dianthicola ME23 0.66 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.62 DZA65_RS19210 3-isopropylmalate dehydratase large subunit 0.65 61
Dickeya dianthicola 67-19 0.66 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.62 HGI48_RS18065 3-isopropylmalate dehydratase large subunit low > 71
Hydrogenophaga sp. GW460-11-11-14-LB1 0.66 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.75 GFF3363 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 90
Acidovorax sp. GW101-3H11 0.65 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.74 Ac3H11_1525 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.92 12
Variovorax sp. OAS795 0.65 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.75 ABID97_RS08465 3-isopropylmalate dehydratase large subunit
Azospirillum brasilense Sp245 0.64 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.68 AZOBR_RS03545 isopropylmalate isomerase 0.55 20
Magnetospirillum magneticum AMB-1 0.63 AMB_RS01125 phosphomethylpyrimidine synthase 0.64 AMB_RS20560 3-isopropylmalate dehydratase large subunit
Sinorhizobium meliloti 1021 0.62 SM_b20615 thiamine biosynthesis protein ThiC 0.66 SMc03823 isopropylmalate isomerase large subunit low > 103
Phaeobacter inhibens DSM 17395 0.62 PGA1_c09110 thiamine biosynthesis protein ThiC 0.59 PGA1_c29780 3-isopropylmalate dehydratase large subunit low > 62
Sphingomonas koreensis DSMZ 15582 0.62 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.58 Ga0059261_4223 3-isopropylmalate dehydratase, large subunit 0.89 45
Dinoroseobacter shibae DFL-12 0.62 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.58 Dshi_0085 3-isopropylmalate dehydratase, large subunit (RefSeq)
Agrobacterium fabrum C58 0.62 Atu2569 thiamine biosynthesis protein 0.65 Atu2709 3-isopropylmalate dehydratase, large subunit 0.72 23
Caulobacter crescentus NA1000 0.61 CCNA_02109 thiamine biosynthesis protein thiC 0.62 CCNA_00196 3-isopropylmalate dehydratase large subunit low > 66
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_02109 thiamine biosynthesis protein thiC 0.62 CCNA_00196 3-isopropylmalate dehydratase large subunit low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.60 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.46 A4249_RS10005 3-isopropylmalate dehydratase large subunit low > 48
Bosea sp. OAE506 0.60 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.66 ABIE41_RS11660 3-isopropylmalate dehydratase large subunit
Rhodopseudomonas palustris CGA009 0.60 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.64 TX73_001245 3-isopropylmalate dehydratase large subunit
Azospirillum sp. SherDot2 0.60 MPMX19_00336 Phosphomethylpyrimidine synthase 0.68 MPMX19_01998 3-isopropylmalate dehydratase large subunit low > 112
Rhodospirillum rubrum S1H 0.57 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.69 Rru_A1189 3-isopropylmalate dehydratase large subunit region (NCBI) low > 58
Phocaeicola dorei CL03T12C01 0.56 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.50 ABI39_RS10200 3-isopropylmalate dehydratase large subunit 0.60 28
Bacteroides stercoris CC31F 0.56 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.50 HMPREF1181_RS14145 3-isopropylmalate dehydratase large subunit low > 56
Phocaeicola vulgatus CL09T03C04 0.56 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.49 HMPREF1058_RS14550 3-isopropylmalate dehydratase large subunit 0.68 53
Bacteroides ovatus ATCC 8483 0.56 BACOVA_02358 thiamine biosynthesis protein ThiC 0.50 BACOVA_04603 3-isopropylmalate dehydratase, large subunit 0.80 12
Bacteroides thetaiotaomicron VPI-5482 0.56 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.50 BT1860 3-isopropylmalate dehydratase large subunit (NCBI ptt file) 0.38 62
Parabacteroides merdae CL09T00C40 0.56 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC 0.49 HMPREF1078_RS16660 3-isopropylmalate dehydratase large subunit low > 61
Mycobacterium tuberculosis H37Rv 0.51 Rv0423c Probable thiamine biosynthesis protein ThiC 0.57 Rv2988c Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI)

Not shown: 0 genomes with orthologs for BPHYT_RS13220 only; 5 genomes with orthologs for BPHYT_RS33915 only