Conservation of cofitness between BBR_RS15810 and BBR_RS12345 in Bifidobacterium breve UCC2003

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bifidobacterium breve UCC2003 1.0 BBR_RS15810 tryptophan synthase subunit alpha 1.0 BBR_RS12345 acetolactate synthase small subunit 0.27 15
Mycobacterium tuberculosis H37Rv 0.40 Rv1613 Probable tryptophan synthase, alpha subunit TrpA 0.52 Rv3002c Probable acetolactate synthase (small subunit) IlvN (acetohydroxy-acid synthase) (AHAS) (ALS)
Rhizobium sp. OAE497 0.27 ABIE40_RS19340 tryptophan synthase subunit alpha 0.33 ABIE40_RS11490 acetolactate synthase small subunit
Methanococcus maripaludis S2 0.27 MMP_RS05185 tryptophan synthase subunit alpha 0.42 MMP_RS03420 acetolactate synthase small subunit
Pseudomonas stutzeri RCH2 0.27 Psest_0062 tryptophan synthase, alpha subunit 0.38 Psest_1037 acetolactate synthase, small subunit 0.64 23
Methanococcus maripaludis JJ 0.26 MMJJ_RS09195 tryptophan synthase subunit alpha 0.41 MMJJ_RS01645 acetolactate synthase small subunit
Synechococcus elongatus PCC 7942 0.26 Synpcc7942_0411 trpA tryptophan synthase subunit alpha 0.44 Synpcc7942_2434 ilvH acetolactate synthase 3 regulatory subunit
Pseudomonas sp. S08-1 0.26 OH686_12430 tryptophan synthase, alpha subunit 0.38 OH686_08125 acetolactate synthase, small subunit 0.72 40
Marinobacter adhaerens HP15 0.26 HP15_1826 tryptophan synthase, alpha subunit 0.38 HP15_532 acetolactate synthase 3 regulatory subunit
Agrobacterium fabrum C58 0.26 Atu0019 tryptophan synthase alpha subunit 0.33 Atu2035 acetolactate synthase, small subunit
Phaeobacter inhibens DSM 17395 0.26 PGA1_c04930 tryptophan synthase alpha chain 0.31 PGA1_c20220 acetolactate synthase isozyme 3 small subunit
Rhodopseudomonas palustris CGA009 0.26 TX73_000365 tryptophan synthase subunit alpha 0.34 TX73_010470 acetolactate synthase small subunit
Magnetospirillum magneticum AMB-1 0.26 AMB_RS20300 tryptophan synthase subunit alpha 0.34 AMB_RS17745 acetolactate synthase small subunit
Pseudomonas fluorescens SBW25 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.38 PFLU_RS25645 acetolactate synthase small subunit 0.79 8
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.38 PFLU_RS25645 acetolactate synthase small subunit 0.45 29
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_10705 tryptophan synthase subunit alpha 0.38 AO353_14500 acetolactate synthase 3 regulatory subunit 0.83 10
Pseudomonas simiae WCS417 0.25 PS417_00180 tryptophan synthase subunit alpha 0.38 PS417_23805 acetolactate synthase 3 regulatory subunit 0.63 28
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_10910 tryptophan synthase subunit alpha 0.38 AO356_16175 acetolactate synthase 3 regulatory subunit 0.95 10
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_565 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.38 PfGW456L13_1539 Acetolactate synthase small subunit (EC 2.2.1.6) 0.81 29
Dinoroseobacter shibae DFL-12 0.25 Dshi_0952 tryptophan synthase, alpha subunit (RefSeq) 0.29 Dshi_1781 acetolactate synthase, small subunit (RefSeq)
Pseudomonas sp. RS175 0.25 PFR28_04716 Tryptophan synthase alpha chain 0.38 PFR28_03698 Acetolactate synthase isozyme 3 small subunit
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_1830 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.38 Pf1N1B4_2879 Acetolactate synthase small subunit (EC 2.2.1.6) 0.87 11
Sinorhizobium meliloti 1021 0.25 SMc02765 tryptophan synthase subunit alpha 0.33 SMc01430 acetolactate synthase 3 regulatory subunit 0.64 82
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4047 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.38 Pf6N2E2_5176 Acetolactate synthase small subunit (EC 2.2.1.6) 0.94 1
Mucilaginibacter yixingensis YX-36 DSM 26809 0.25 ABZR88_RS10660 tryptophan synthase subunit alpha 0.24 ABZR88_RS11585 acetolactate synthase small subunit
Acinetobacter radioresistens SK82 0.25 MPMX26_02611 Tryptophan synthase alpha chain 0.40 MPMX26_00473 Acetolactate synthase isozyme 3 small subunit
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.38 Psyr_0847 acetolactate synthase, small subunit 0.67 16
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.38 Psyr_0847 acetolactate synthase, small subunit 0.68 5
Pseudomonas putida KT2440 0.24 PP_0082 tryptophan synthase alpha chain 0.37 PP_4679 acetohydroxybutanoate synthase / acetolactate synthase 0.83 13
Acidovorax sp. GW101-3H11 0.24 Ac3H11_1535 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.37 Ac3H11_526 Acetolactate synthase small subunit (EC 2.2.1.6) 0.72 48
Parabacteroides merdae CL09T00C40 0.23 HMPREF1078_RS00120 tryptophan synthase subunit alpha 0.22 HMPREF1078_RS16685 acetolactate synthase small subunit low > 61
Dechlorosoma suillum PS 0.23 Dsui_3191 tryptophan synthase, alpha subunit 0.33 Dsui_3528 acetolactate synthase, small subunit
Variovorax sp. SCN45 0.23 GFF3882 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.38 GFF1159 Acetolactate synthase small subunit (EC 2.2.1.6)
Phocaeicola dorei CL03T12C01 0.23 ABI39_RS21075 tryptophan synthase subunit alpha 0.22 ABI39_RS12725 acetolactate synthase small subunit 0.60 56
Phocaeicola vulgatus CL09T03C04 0.23 HMPREF1058_RS07200 tryptophan synthase subunit alpha 0.21 HMPREF1058_RS16825 acetolactate synthase small subunit 0.82 35
Bosea sp. OAE506 0.23 ABIE41_RS03930 tryptophan synthase subunit alpha 0.33 ABIE41_RS12905 acetolactate synthase small subunit
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS15350 tryptophan synthase subunit alpha 0.20 HMPREF1181_RS08325 acetolactate synthase small subunit 0.82 36
Shewanella oneidensis MR-1 0.23 SO3024 trpA tryptophan synthase, alpha subunit (NCBI ptt file) 0.32 SO2278 ilvH acetolactate synthase III, small subunit (NCBI ptt file)
Serratia liquefaciens MT49 0.22 IAI46_14045 tryptophan synthase subunit alpha 0.34 IAI46_03380 acetolactate synthase small subunit low > 86
Bacteroides thetaiotaomicron VPI-5482 0.22 BT0527 tryptophan synthase alpha chain (NCBI ptt file) 0.20 BT2076 acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) (from data) 0.74 36
Shewanella sp. ANA-3 0.22 Shewana3_1515 trpA tryptophan synthase subunit alpha (RefSeq) 0.33 Shewana3_2270 ilvH acetolactate synthase 3 regulatory subunit (RefSeq) low > 73
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS14350 tryptophan synthase alpha chain 0.38 RR42_RS05440 acetolactate synthase
Azospirillum brasilense Sp245 0.22 AZOBR_RS00520 tryptophan synthase subunit alpha 0.34 AZOBR_RS06565 acetolactate synthase low > 97
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS14490 tryptophan synthase subunit alpha 0.38 ABZR87_RS14950 acetolactate synthase small subunit 0.68 38
Bacteroides ovatus ATCC 8483 0.22 BACOVA_03785 tryptophan synthase, alpha subunit 0.21 BACOVA_03304 acetolactate synthase, small subunit 0.93 24
Vibrio cholerae E7946 ATCC 55056 0.22 CSW01_05925 tryptophan synthase subunit alpha 0.37 CSW01_12560 acetolactate synthase small subunit low > 62
Variovorax sp. OAS795 0.22 ABID97_RS08425 tryptophan synthase subunit alpha 0.39 ABID97_RS14890 acetolactate synthase small subunit low > 91
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_03657 tryptophan synthase alpha chain 0.32 CCNA_02186 acetolactate synthase small subunit low > 67
Caulobacter crescentus NA1000 0.22 CCNA_03657 tryptophan synthase alpha chain 0.32 CCNA_02186 acetolactate synthase small subunit low > 66
Ralstonia solanacearum PSI07 0.21 RPSI07_RS14740 tryptophan synthase subunit alpha 0.36 RPSI07_RS14260 acetolactate synthase small subunit
Ralstonia solanacearum GMI1000 0.21 RS_RS09955 tryptophan synthase subunit alpha 0.36 RS_RS10415 acetolactate synthase small subunit low > 80
Azospirillum sp. SherDot2 0.21 MPMX19_02737 Tryptophan synthase alpha chain 0.34 MPMX19_01775 Acetolactate synthase isozyme 3 small subunit
Pantoea sp. MT58 0.21 IAI47_09165 tryptophan synthase subunit alpha 0.35 IAI47_15985 acetolactate synthase small subunit low > 76
Ralstonia solanacearum UW163 0.21 UW163_RS11150 tryptophan synthase subunit alpha 0.36 UW163_RS10680 acetolactate synthase small subunit
Ralstonia solanacearum IBSBF1503 0.21 RALBFv3_RS02575 tryptophan synthase subunit alpha 0.36 RALBFv3_RS03045 acetolactate synthase small subunit
Alteromonas macleodii MIT1002 0.21 MIT1002_01425 Tryptophan synthase alpha chain 0.36 MIT1002_00504 Acetolactate synthase isozyme 3 small subunit
Klebsiella michiganensis M5al 0.21 BWI76_RS11840 tryptophan synthase subunit alpha 0.35 BWI76_RS04700 acetolactate synthase small subunit low > 92
Herbaspirillum seropedicae SmR1 0.21 HSERO_RS16470 tryptophan synthase subunit alpha 0.37 HSERO_RS08655 acetolactate synthase 0.42 59
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_1740 trpA tryptophan synthase subunit alpha (RefSeq) 0.44 DvMF_0154 ilvH acetolactate synthase 3 regulatory subunit (RefSeq) low > 51
Paraburkholderia graminis OAS925 0.21 ABIE53_004811 tryptophan synthase alpha chain 0.37 ABIE53_001575 acetolactate synthase-1/3 small subunit low > 113
Dickeya dianthicola ME23 0.20 DZA65_RS10940 tryptophan synthase subunit alpha 0.34 DZA65_RS19180 acetolactate synthase small subunit low > 75
Dickeya dianthicola 67-19 0.20 HGI48_RS10460 tryptophan synthase subunit alpha 0.34 HGI48_RS18035 acetolactate synthase small subunit low > 71
Dickeya dadantii 3937 0.20 DDA3937_RS10460 tryptophan synthase subunit alpha 0.34 DDA3937_RS18100 acetolactate synthase small subunit low > 74
Shewanella loihica PV-4 0.20 Shew_2256 trpA tryptophan synthase subunit alpha (RefSeq) 0.36 Shew_1775 acetolactate synthase 3 regulatory subunit (RefSeq) low > 60
Enterobacter asburiae PDN3 0.20 EX28DRAFT_0932 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.36 EX28DRAFT_3674 acetolactate synthase, small subunit (EC 2.2.1.6) low > 76
Rahnella sp. WP5 0.20 EX31_RS09980 tryptophan synthase subunit alpha 0.35 EX31_RS03660 acetolactate synthase small subunit low > 89
Enterobacter sp. TBS_079 0.20 MPMX20_02514 Tryptophan synthase alpha chain 0.35 MPMX20_00772 Acetolactate synthase isozyme 3 small subunit low > 85
Escherichia fergusonii Becca 0.20 EFB2_02666 Tryptophan synthase alpha chain 0.35 EFB2_03968 Acetolactate synthase isozyme 3 small subunit low > 86
Escherichia coli ECOR38 0.19 HEPCGN_25515 trpA tryptophan synthase subunit alpha 0.35 HEPCGN_08675 ilvN acetolactate synthase small subunit low > 87
Escherichia coli BW25113 0.19 b1260 trpA tryptophan synthase subunit alpha (NCBI) 0.36 b0078 ilvH acetolactate synthase small subunit (NCBI) low > 76
Escherichia coli BL21 0.19 ECD_01234 tryptophan synthase, alpha subunit 0.36 ECD_00080 acetolactate synthase 3, small subunit, valine-sensitive low > 61
Escherichia coli Nissle 1917 0.19 ECOLIN_RS07595 tryptophan synthase subunit alpha 0.35 ECOLIN_RS00420 acetolactate synthase small subunit
Escherichia coli HS(pFamp)R (ATCC 700891) 0.19 OHPLBJKB_02423 Tryptophan synthase alpha chain 0.35 OHPLBJKB_03580 Acetolactate synthase isozyme 3 small subunit low > 73
Escherichia coli ECRC62 0.19 BNILDI_18480 trpA tryptophan synthase subunit alpha 0.35 BNILDI_08570 ilvN acetolactate synthase small subunit low > 75
Pectobacterium carotovorum WPP14 0.19 HER17_RS10940 tryptophan synthase subunit alpha 0.35 HER17_RS03100 acetolactate synthase small subunit low > 75
Erwinia tracheiphila SCR3 0.19 LU632_RS12775 trpA tryptophan synthase subunit alpha 0.35 LU632_RS02890 ilvN acetolactate synthase small subunit low > 74
Escherichia coli ECOR27 0.19 NOLOHH_20335 trpA tryptophan synthase subunit alpha 0.35 NOLOHH_03040 ilvN acetolactate synthase small subunit low > 75
Escherichia coli ECRC98 0.19 JDDGAC_05220 trpA tryptophan synthase subunit alpha 0.35 JDDGAC_14290 ilvN acetolactate synthase small subunit low > 86
Escherichia coli ECRC101 0.19 MCAODC_15590 trpA tryptophan synthase subunit alpha 0.35 MCAODC_01210 ilvN acetolactate synthase small subunit low > 87
Escherichia coli ECRC99 0.19 KEDOAH_26075 trpA tryptophan synthase subunit alpha 0.35 KEDOAH_17460 ilvN acetolactate synthase small subunit
Escherichia coli ECRC100 0.19 OKFHMN_02675 trpA tryptophan synthase subunit alpha 0.35 OKFHMN_10695 ilvN acetolactate synthase small subunit low > 80
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.19 GFF2726 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.35 GFF160 Acetolactate synthase small subunit (EC 2.2.1.6) low > 78
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_06065 tryptophan synthase, alpha chain 0.37 H281DRAFT_04552 acetolactate synthase, small subunit low > 103
Escherichia coli ECRC102 0.19 NIAGMN_26845 trpA tryptophan synthase subunit alpha 0.35 NIAGMN_08545 ilvN acetolactate synthase small subunit
Castellaniella sp019104865 MT123 0.19 ABCV34_RS08430 tryptophan synthase subunit alpha 0.33 ABCV34_RS01215 acetolactate synthase small subunit
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS33865 tryptophan synthase alpha chain 0.37 BPHYT_RS06550 acetolactate synthase low > 109
Shewanella amazonensis SB2B 0.18 Sama_2134 trpA tryptophan synthase subunit alpha (RefSeq) 0.35 Sama_2019 ilvH acetolactate synthase 3 regulatory subunit (RefSeq) low > 62
Paraburkholderia sabiae LMG 24235 0.18 QEN71_RS17655 tryptophan synthase subunit alpha 0.37 QEN71_RS24220 acetolactate synthase small subunit low > 153
Sphingomonas koreensis DSMZ 15582 0.18 Ga0059261_0239 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.37 Ga0059261_0067 acetolactate synthase, small subunit (EC 2.2.1.6) 0.88 20

Not shown: 3 genomes with orthologs for BBR_RS15810 only; 6 genomes with orthologs for BBR_RS12345 only