Conservation of cofitness between b4235 and b3652 in Escherichia coli BW25113

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b4235 pmbA predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) 1.0 b3652 recG ATP-dependent DNA helicase (NCBI) 0.27 20
Escherichia coli ECRC98 1.00 JDDGAC_15565 pmbA metalloprotease PmbA 0.99 JDDGAC_19170 recG ATP-dependent DNA helicase RecG
Escherichia coli ECRC101 1.00 MCAODC_02430 pmbA metalloprotease PmbA 0.99 MCAODC_06055 recG ATP-dependent DNA helicase RecG
Escherichia coli ECOR38 1.00 HEPCGN_10125 pmbA metalloprotease PmbA 0.99 HEPCGN_14365 recG ATP-dependent DNA helicase RecG low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03800 Metalloprotease PmbA 1.00 OHPLBJKB_00049 ATP-dependent DNA helicase RecG low > 73
Escherichia coli ECRC102 1.00 NIAGMN_09775 pmbA metalloprotease PmbA 0.99 NIAGMN_13305 recG ATP-dependent DNA helicase RecG
Escherichia coli ECRC101 1.00 OKFHMN_11925 pmbA metalloprotease PmbA 0.99 OKFHMN_15545 recG ATP-dependent DNA helicase RecG
Escherichia coli ECRC62 1.00 BNILDI_07325 pmbA metalloprotease PmbA 1.00 BNILDI_04090 recG ATP-dependent DNA helicase RecG
Escherichia coli ECOR27 1.00 NOLOHH_04185 pmbA metalloprotease PmbA 0.99 NOLOHH_07425 recG ATP-dependent DNA helicase RecG low > 57
Escherichia coli ECRC99 1.00 KEDOAH_16230 pmbA metalloprotease PmbA 0.99 KEDOAH_12600 recG ATP-dependent DNA helicase RecG
Escherichia coli BL21 1.00 ECD_04103 putative antibiotic peptide MccB17 maturation peptidase 1.00 ECD_03509 ATP-dependent DNA helicase low > 60
Escherichia fergusonii Becca 0.99 EFB2_04298 Metalloprotease PmbA 0.99 EFB2_00136 ATP-dependent DNA helicase RecG low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS24570 metalloprotease PmbA 0.99 ECOLIN_RS20800 ATP-dependent DNA helicase RecG low > 52
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF904 TldE protein, part of TldE/TldD proteolytic complex 0.94 GFF355 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 78
Enterobacter sp. TBS_079 0.97 MPMX20_00517 Metalloprotease PmbA 0.92 MPMX20_00084 ATP-dependent DNA helicase RecG low > 85
Enterobacter asburiae PDN3 0.96 EX28DRAFT_3422 Predicted Zn-dependent proteases and their inactivated homologs 0.93 EX28DRAFT_3901 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 76
Klebsiella michiganensis M5al 0.94 BWI76_RS02850 metalloprotease PmbA 0.91 BWI76_RS27440 DNA helicase RecG low > 92
Serratia liquefaciens MT49 0.86 IAI46_22575 metalloprotease PmbA 0.84 IAI46_24905 ATP-dependent DNA helicase RecG low > 86
Rahnella sp. WP5 0.85 EX31_RS12320 metalloprotease PmbA 0.80 EX31_RS15820 ATP-dependent DNA helicase RecG low > 89
Pectobacterium carotovorum WPP14 0.84 HER17_RS20090 metalloprotease PmbA 0.82 HER17_RS21395 ATP-dependent DNA helicase RecG low > 75
Pantoea sp. MT58 0.84 IAI47_02765 metalloprotease PmbA 0.84 IAI47_00500 ATP-dependent DNA helicase RecG low > 76
Dickeya dadantii 3937 0.81 DDA3937_RS01500 metalloprotease PmbA 0.80 DDA3937_RS00170 ATP-dependent DNA helicase RecG low > 74
Erwinia tracheiphila SCR3 0.81 LU632_RS02145 pmbA metalloprotease PmbA 0.82 LU632_RS22190 recG ATP-dependent DNA helicase RecG low > 74
Dickeya dianthicola ME23 0.81 DZA65_RS01480 metalloprotease PmbA 0.80 DZA65_RS22160 ATP-dependent DNA helicase RecG low > 75
Dickeya dianthicola 67-19 0.81 HGI48_RS01415 metalloprotease PmbA 0.80 HGI48_RS21190 ATP-dependent DNA helicase RecG 0.72 13
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_12845 metalloprotease PmbA 0.66 CSW01_13680 DNA helicase RecG low > 62
Shewanella amazonensis SB2B 0.59 Sama_0482 PmbA protein (RefSeq) 0.65 Sama_3375 ATP-dependent DNA helicase RecG (RefSeq) low > 62
Shewanella sp. ANA-3 0.59 Shewana3_3631 microcin-processing peptidase 1 (RefSeq) 0.65 Shewana3_0348 ATP-dependent DNA helicase RecG (RefSeq) low > 73
Shewanella oneidensis MR-1 0.59 SO4078 pmbA pmba protein (NCBI ptt file) 0.64 SO4364 recG ATP-dependent DNA helicase RecG (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.57 Shew_0416 peptidase U62, modulator of DNA gyrase (RefSeq) 0.64 Shew_3507 ATP-dependent DNA helicase RecG (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.54 MIT1002_00230 peptidase PmbA 0.62 MIT1002_00111 ATP-dependent DNA helicase RecG low > 70
Pseudomonas sp. RS175 0.48 PFR28_00163 Metalloprotease PmbA 0.54 PFR28_04435 ATP-dependent DNA helicase RecG low > 88
Pseudomonas fluorescens SBW25 0.48 PFLU_RS04350 metalloprotease PmbA 0.55 PFLU_RS29550 ATP-dependent DNA helicase RecG low > 109
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS04350 metalloprotease PmbA 0.55 PFLU_RS29550 ATP-dependent DNA helicase RecG low > 109
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_3278 TldE protein, part of TldE/TldD proteolytic complex 0.54 Pf6N2E2_4352 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 103
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_07085 peptidase PmbA 0.54 AO356_12380 ATP-dependent DNA helicase RecG low > 104
Pseudomonas simiae WCS417 0.47 PS417_04295 peptidase PmbA 0.55 PS417_27870 ATP-dependent DNA helicase RecG 0.42 63
Pseudomonas putida KT2440 0.47 PP_0942 regulatory protease 0.55 PP_5310 junction-specific ATP-dependent DNA helicase low > 96
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_1090 TldE protein, part of TldE/TldD proteolytic complex 0.55 Pf1N1B4_2105 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 87
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_05205 peptidase PmbA 0.55 AO353_09320 ATP-dependent DNA helicase RecG low > 101
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_5024 TldE protein, part of TldE/TldD proteolytic complex 0.55 PfGW456L13_772 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.54 Psyr_0201 ATP-dependent DNA helicase RecG low > 86
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.54 Psyr_0201 ATP-dependent DNA helicase RecG low > 86
Herbaspirillum seropedicae SmR1 0.46 HSERO_RS09265 peptidase C69 0.44 HSERO_RS06165 ATP-dependent DNA helicase RecG low > 78
Pseudomonas stutzeri RCH2 0.45 Psest_3318 Predicted Zn-dependent proteases and their inactivated homologs 0.55 Psest_4192 ATP-dependent DNA helicase RecG
Variovorax sp. OAS795 0.45 ABID97_RS20695 metalloprotease PmbA 0.40 ABID97_RS01575 ATP-dependent DNA helicase RecG low > 91
Xanthomonas campestris pv. campestris strain 8004 0.45 Xcc-8004.1885.1 TldE protein, part of TldE/TldD proteolytic complex 0.51 Xcc-8004.1204.1 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 74
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS21700 metalloprotease PmbA 0.52 ABZR86_RS11840 ATP-dependent DNA helicase RecG low > 74
Pseudomonas sp. S08-1 0.45 OH686_08570 TldE protein, part of TldE/TldD proteolytic complex 0.54 OH686_13505 ATP-dependent DNA helicase RecG low > 80
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_10260 pmbA metalloprotease PmbA 0.51 OKGIIK_12090 recG ATP-dependent DNA helicase RecG low > 52
Variovorax sp. SCN45 0.45 GFF4697 TldE protein, part of TldE/TldD proteolytic complex 0.38 GFF5538 ATP-dependent DNA helicase RecG (EC 3.6.4.12) 0.83 33
Rhodanobacter denitrificans MT42 0.44 LRK55_RS03125 metalloprotease PmbA 0.51 LRK55_RS11530 ATP-dependent DNA helicase RecG low > 63
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS03375 metalloprotease PmbA 0.51 LRK54_RS11805 ATP-dependent DNA helicase RecG low > 59
Dechlorosoma suillum PS 0.44 Dsui_1234 putative Zn-dependent protease-like protein 0.41 Dsui_0311 ATP-dependent DNA helicase RecG 0.92 1
Acidovorax sp. GW101-3H11 0.44 Ac3H11_3262 TldE protein, part of TldE/TldD proteolytic complex 0.44 Ac3H11_781 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 79
Ralstonia solanacearum UW163 0.43 UW163_RS15845 metalloprotease PmbA 0.44 UW163_RS07950 DNA helicase RecG
Ralstonia solanacearum IBSBF1503 0.43 RALBFv3_RS13965 metalloprotease PmbA 0.44 RALBFv3_RS05675 DNA helicase RecG low > 76
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS09660 metalloprotease PmbA 0.44 ABZR87_RS01270 ATP-dependent DNA helicase RecG low > 80
Paraburkholderia graminis OAS925 0.43 ABIE53_003116 PmbA protein 0.45 ABIE53_000833 ATP-dependent DNA helicase RecG low > 113
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_04304 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.45 H281DRAFT_04672 ATP-dependent DNA helicase RecG low > 103
Ralstonia solanacearum PSI07 0.43 RPSI07_RS19505 metalloprotease PmbA 0.44 RPSI07_RS11625 DNA helicase RecG low > 81
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS04270 metalloprotease PmbA 0.45 QEN71_RS26630 ATP-dependent DNA helicase RecG
Kangiella aquimarina DSM 16071 0.43 B158DRAFT_2075 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.48 B158DRAFT_0566 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 40
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS14705 peptidase C69 0.45 BPHYT_RS03400 ATP-dependent DNA helicase RecG low > 109
Castellaniella sp019104865 MT123 0.42 ABCV34_RS10610 metalloprotease PmbA 0.43 ABCV34_RS03570 ATP-dependent DNA helicase RecG low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF3655 TldE protein, part of TldE/TldD proteolytic complex 0.41 GFF2802 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 90
Lysobacter sp. OAE881 0.41 ABIE51_RS06805 metalloprotease PmbA 0.53 ABIE51_RS17230 ATP-dependent DNA helicase RecG low > 62
Ralstonia solanacearum GMI1000 0.41 RS_RS04700 metalloprotease PmbA 0.45 RS_RS13565 DNA helicase RecG
Cupriavidus basilensis FW507-4G11 0.41 RR42_RS14750 peptidase PMbA 0.44 RR42_RS17390 ATP-dependent DNA helicase RecG low > 128
Azospirillum brasilense Sp245 0.34 AZOBR_RS11930 modulator protein 0.33 AZOBR_RS09850 ATP-dependent DNA helicase RecG low > 97
Azospirillum sp. SherDot2 0.34 MPMX19_01886 Metalloprotease PmbA 0.34 MPMX19_00951 ATP-dependent DNA helicase RecG
Sphingomonas koreensis DSMZ 15582 0.30 Ga0059261_0810 Predicted Zn-dependent proteases and their inactivated homologs 0.30 Ga0059261_0958 ATP-dependent DNA helicase RecG (EC 3.6.1.-) low > 68
Magnetospirillum magneticum AMB-1 0.29 AMB_RS22120 TldD/PmbA family protein 0.33 AMB_RS12400 ATP-dependent DNA helicase RecG
Rhodopseudomonas palustris CGA009 0.29 TX73_005930 TldD/PmbA family protein 0.30 TX73_013795 ATP-dependent DNA helicase RecG low > 86
Rhodospirillum rubrum S1H 0.29 Rru_A0575 Peptidase U62, modulator of DNA gyrase (NCBI) 0.30 Rru_A1728 ATP-dependent DNA helicase RecG (NCBI)
Caulobacter crescentus NA1000 0.28 CCNA_00311 Zn-dependent protease family protein 0.31 CCNA_01504 ATP-dependent DNA helicase recG low > 66
Caulobacter crescentus NA1000 Δfur 0.28 CCNA_00311 Zn-dependent protease family protein 0.31 CCNA_01504 ATP-dependent DNA helicase recG low > 67
Sinorhizobium meliloti 1021 0.28 SMc00897 PMBA protein 0.33 SMc00228 ATP-dependent DNA helicase RecG low > 103
Brevundimonas sp. GW460-12-10-14-LB2 0.28 A4249_RS09195 TldD/PmbA family protein 0.28 A4249_RS04765 ATP-dependent DNA helicase RecG low > 48
Agrobacterium fabrum C58 0.27 Atu0693 PmbA/TldD related protein 0.34 Atu1780 ATP-dependent DNA helicase low > 89
Phaeobacter inhibens DSM 17395 0.27 PGA1_c33480 protein PmbA 0.34 PGA1_c14380 ATP-dependent DNA helicase RecG
Rhizobium sp. OAE497 0.26 ABIE40_RS03780 TldD/PmbA family protein 0.34 ABIE40_RS09300 ATP-dependent DNA helicase RecG low > 107
Dinoroseobacter shibae DFL-12 0.26 Dshi_0064 peptidase U62 modulator of DNA gyrase (RefSeq) 0.32 Dshi_1510 DEAD/DEAH box helicase domain protein (RefSeq) low > 64
Bacteroides thetaiotaomicron VPI-5482 0.19 BT3649 putative modulator of DNA gyrase (NCBI ptt file) 0.33 BT3924 ATP-dependent DNA helicase recG (NCBI ptt file)
Bacteroides stercoris CC31F 0.17 HMPREF1181_RS03170 TldD/PmbA family protein 0.32 HMPREF1181_RS06615 ATP-dependent DNA helicase RecG low > 56
Parabacteroides merdae CL09T00C40 0.16 HMPREF1078_RS03625 TldD/PmbA family protein 0.32 HMPREF1078_RS12765 ATP-dependent DNA helicase RecG
Synechococcus elongatus PCC 7942 0.09 Synpcc7942_1289 pmbA putative modulator of DNA gyrase 0.33 Synpcc7942_1079 recG ATP-dependent DNA helicase RecG
Pedobacter sp. GW460-11-11-14-LB5 0.06 CA265_RS02445 peptidase C69 0.31 CA265_RS22835 ATP-dependent DNA helicase RecG low > 88
Pontibacter actiniarum KMM 6156, DSM 19842 0.06 CA264_16645 peptidase C69 0.31 CA264_15020 DNA helicase RecG low > 74

Not shown: 0 genomes with orthologs for b4235 only; 9 genomes with orthologs for b3652 only