Conservation of cofitness between b0945 and b2329 in Escherichia coli BW25113

91 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 1.0 b2329 aroC chorismate synthase (NCBI) 0.81 19
Escherichia coli BL21 1.00 ECD_00949 dihydro-orotate oxidase, FMN-linked 1.00 ECD_02254 chorismate synthase low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 1.00 OHPLBJKB_01376 Chorismate synthase low > 73
Escherichia coli ECRC98 1.00 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 JDDGAC_26575 aroC chorismate synthase — —
Escherichia coli ECRC101 1.00 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 MCAODC_13655 aroC chorismate synthase — —
Escherichia coli ECRC101 1.00 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 OKFHMN_22615 aroC chorismate synthase — —
Escherichia coli ECRC102 1.00 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 NIAGMN_20390 aroC chorismate synthase — —
Escherichia coli ECRC62 1.00 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.99 BNILDI_13170 aroC chorismate synthase — —
Escherichia coli ECOR27 1.00 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 0.99 NOLOHH_14250 aroC chorismate synthase — —
Escherichia coli ECRC99 1.00 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 KEDOAH_05580 aroC chorismate synthase — —
Escherichia coli ECOR38 1.00 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 HEPCGN_21820 aroC chorismate synthase low > 85
Escherichia fergusonii Becca 0.99 EFB2_03126 Dihydroorotate dehydrogenase (quinone) 1.00 EFB2_01529 Chorismate synthase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase 1.00 ECOLIN_RS13490 chorismate synthase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.93 GFF1950 Chorismate synthase (EC 4.2.3.5) low > 78
Enterobacter asburiae PDN3 0.94 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) 0.89 EX28DRAFT_0275 chorismate synthase (EC 4.2.3.5) — —
Enterobacter sp. TBS_079 0.94 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.89 MPMX20_03264 Chorismate synthase 0.78 44
Klebsiella michiganensis M5al 0.93 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.91 BWI76_RS20435 chorismate synthase 0.44 86
Serratia liquefaciens MT49 0.87 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.86 IAI46_18025 chorismate synthase 0.76 33
Pectobacterium carotovorum WPP14 0.86 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.85 HER17_RS06935 chorismate synthase 0.91 52
Dickeya dianthicola ME23 0.86 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.85 DZA65_RS15465 chorismate synthase — —
Rahnella sp. WP5 0.86 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.85 EX31_RS19685 chorismate synthase — —
Dickeya dadantii 3937 0.86 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.86 DDA3937_RS14580 chorismate synthase — —
Dickeya dianthicola 67-19 0.85 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.85 HGI48_RS14530 chorismate synthase — —
Erwinia tracheiphila SCR3 0.84 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.87 LU632_RS07775 aroC chorismate synthase 0.78 33
Pantoea sp. MT58 0.81 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.83 IAI47_06150 chorismate synthase — —
Vibrio cholerae E7946 ATCC 55056 0.72 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.77 CSW01_10560 chorismate synthase low > 62
Shewanella sp. ANA-3 0.63 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.75 Shewana3_1469 chorismate synthase (RefSeq) 0.88 16
Shewanella loihica PV-4 0.63 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.74 Shew_2416 chorismate synthase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.62 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.77 Sama_2159 chorismate synthase (RefSeq) — —
Alteromonas macleodii MIT1002 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.75 MIT1002_01229 Chorismate synthase — —
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.67 PFLU_RS21280 chorismate synthase — —
Pseudomonas fluorescens SBW25 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.67 PFLU_RS21280 chorismate synthase — —
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase 0.66 QEN71_RS05215 chorismate synthase — —
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.67 Pf1N1B4_3780 Chorismate synthase (EC 4.2.3.5) — —
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.67 AO353_02250 chorismate synthase — —
Pseudomonas simiae WCS417 0.57 PS417_20935 dihydroorotate dehydrogenase 0.67 PS417_19315 chorismate synthase — —
Burkholderia phytofirmans PsJN 0.57 BPHYT_RS08565 dihydroorotate dehydrogenase 0.66 BPHYT_RS13705 chorismate synthase 0.63 31
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_2106 dihydroorotate oxidase A 0.68 Psyr_1853 chorismate synthase — —
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_2106 dihydroorotate oxidase A 0.68 Psyr_1853 chorismate synthase — —
Paraburkholderia graminis OAS925 0.56 ABIE53_001954 dihydroorotate dehydrogenase 0.67 ABIE53_002916 chorismate synthase — —
Pseudomonas sp. RS175 0.56 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.67 PFR28_03126 Chorismate synthase — —
Pseudomonas fluorescens GW456-L13 0.56 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.68 PfGW456L13_4165 Chorismate synthase (EC 4.2.3.5) — —
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.68 Pf6N2E2_5822 Chorismate synthase (EC 4.2.3.5) — —
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.68 AO356_19540 chorismate synthase — —
Pseudomonas sp. S08-1 0.55 OH686_03120 dihydroorotate dehydrogenase (fumarate) 0.67 OH686_00675 chorismate synthase — —
Dechlorosoma suillum PS 0.55 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 0.66 Dsui_3204 chorismate synthase — —
Kangiella aquimarina DSM 16071 0.55 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) 0.48 B158DRAFT_2433 chorismate synthase (EC 4.2.3.5) — —
Pseudomonas stutzeri RCH2 0.55 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.68 Psest_1903 chorismate synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.55 H281DRAFT_00743 dihydroorotate oxidase A 0.67 H281DRAFT_04489 chorismate synthase — —
Ralstonia sp. UNC404CL21Col 0.54 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase 0.64 ABZR87_RS13790 chorismate synthase — —
Pseudomonas putida KT2440 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.69 PP_1830 Chorismate synthase — —
Ralstonia solanacearum UW163 0.54 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase 0.62 UW163_RS15160 chorismate synthase — —
Ralstonia solanacearum IBSBF1503 0.54 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase 0.62 RALBFv3_RS01850 chorismate synthase — —
Ralstonia solanacearum PSI07 0.53 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase 0.62 RPSI07_RS15640 chorismate synthase — —
Ralstonia solanacearum GMI1000 0.53 RS_RS08160 dihydroorotate dehydrogenase (quinone) 0.61 RS_RS07885 chorismate synthase — —
Acinetobacter radioresistens SK82 0.53 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.67 MPMX26_01340 Chorismate synthase — —
Herbaspirillum seropedicae SmR1 0.52 HSERO_RS16155 dihydroorotate dehydrogenase 0.62 HSERO_RS16525 chorismate synthase — —
Cupriavidus basilensis FW507-4G11 0.51 RR42_RS07465 dihydroorotate dehydrogenase 0.64 RR42_RS06485 chorismate synthase — —
Acidovorax sp. GW101-3H11 0.51 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.64 Ac3H11_2925 Chorismate synthase (EC 4.2.3.5) — —
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase 0.66 ABZR86_RS08040 chorismate synthase — —
Castellaniella sp019104865 MT123 0.50 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase 0.64 ABCV34_RS04300 chorismate synthase — —
Rhodanobacter denitrificans MT42 0.50 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase 0.64 LRK55_RS01505 chorismate synthase — —
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase 0.64 LRK54_RS01725 chorismate synthase — —
Variovorax sp. SCN45 0.49 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) 0.60 GFF2627 Chorismate synthase (EC 4.2.3.5) — —
Variovorax sp. OAS795 0.48 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase 0.60 ABID97_RS19805 chorismate synthase — —
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase 0.66 OKGIIK_04805 aroC chorismate synthase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.47 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.62 GFF5239 Chorismate synthase (EC 4.2.3.5) low > 90
Marinobacter adhaerens HP15 0.47 HP15_1377 dihydroorotate dehydrogenase 0.72 HP15_1838 chorismate synthase — —
Xanthomonas campestris pv. campestris strain 8004 0.47 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.62 Xcc-8004.1955.1 Chorismate synthase (EC 4.2.3.5) — —
Lysobacter sp. OAE881 0.45 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase 0.62 ABIE51_RS08220 chorismate synthase — —
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS14005 dihydroorotate dehydrogenase (quinone) 0.46 CA265_RS11645 chorismate synthase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.42 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 0.48 Echvi_1518 chorismate synthase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.41 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase 0.44 ABZR88_RS06995 chorismate synthase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.41 CA264_00865 dihydroorotate dehydrogenase (quinone) 0.46 CA264_19835 chorismate synthase — —
Sinorhizobium meliloti 1021 0.40 SMc02245 dihydroorotate dehydrogenase 2 0.52 SMc00007 chorismate synthase — —
Agrobacterium fabrum C58 0.40 Atu0486 dihydroorotate dehydrogenase 0.52 Atu0754 chorismate synthase — —
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) 0.50 Ga0059261_2470 chorismate synthase (EC 4.2.3.5) — —
Rhizobium sp. OAE497 0.38 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase 0.52 ABIE40_RS03980 chorismate synthase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.38 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase 0.52 A4249_RS08790 chorismate synthase — —
Rhodopseudomonas palustris CGA009 0.37 TX73_004110 quinone-dependent dihydroorotate dehydrogenase 0.62 TX73_006170 chorismate synthase — —
Azospirillum sp. SherDot2 0.37 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) 0.58 MPMX19_01810 Chorismate synthase — —
Azospirillum brasilense Sp245 0.36 AZOBR_RS13520 dihydroorotate dehydrogenase 0.61 AZOBR_RS10730 chorismate synthase — —
Magnetospirillum magneticum AMB-1 0.36 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase 0.64 AMB_RS08025 chorismate synthase — —
Rhodospirillum rubrum S1H 0.36 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.59 Rru_A2623 Chorismate synthase (NCBI) — —
Mycobacterium tuberculosis H37Rv 0.36 Rv2139 Probable dihydroorotate dehydrogenase PyrD 0.24 Rv2540c Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) — —
Phaeobacter inhibens DSM 17395 0.33 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.54 PGA1_c34060 chorismate synthase AroC — —
Bosea sp. OAE506 0.33 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.62 ABIE41_RS10190 chorismate synthase — —
Dinoroseobacter shibae DFL-12 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.53 Dshi_3275 Chorismate synthase (RefSeq) — —
Caulobacter crescentus NA1000 Δfur 0.31 CCNA_00562 dihydroorotate dehydrogenase 0.52 CCNA_03256 chorismate synthase low > 67
Caulobacter crescentus NA1000 0.31 CCNA_00562 dihydroorotate dehydrogenase 0.52 CCNA_03256 chorismate synthase low > 66
Bacteroides thetaiotaomicron VPI-5482 0.26 BT1009 dihydroorotate dehydrogenase (NCBI ptt file) 0.44 BT2084 chorismate synthase (NCBI ptt file) — —
Bifidobacterium breve UCC2003 0.22 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase 0.26 BBR_RS15080 chorismate synthase low > 34

Not shown: 1 genomes with orthologs for b0945 only; 11 genomes with orthologs for b2329 only