Conservation of cofitness between b1180 and b1260 in Escherichia coli BW25113

92 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1180 ycgM predicted isomerase/hydrolase (NCBI) 1.0 b1260 trpA tryptophan synthase subunit alpha (NCBI) 0.20 12
Escherichia coli ECRC101 0.99 MCAODC_21930 ycgM fumarylacetoacetate hydrolase family protein 0.99 MCAODC_15590 trpA tryptophan synthase subunit alpha
Escherichia coli ECRC102 0.99 NIAGMN_27980 ycgM fumarylacetoacetate hydrolase family protein 0.99 NIAGMN_26845 trpA tryptophan synthase subunit alpha
Escherichia coli ECOR38 0.99 HEPCGN_24690 ycgM fumarylacetoacetate hydrolase family protein 0.94 HEPCGN_25515 trpA tryptophan synthase subunit alpha low > 85
Escherichia coli Nissle 1917 0.99 ECOLIN_RS07140 fumarylacetoacetate hydrolase family protein 0.99 ECOLIN_RS07595 tryptophan synthase subunit alpha
Escherichia coli BL21 0.99 ECD_01155 putative isomerase/hydrolase 1.00 ECD_01234 tryptophan synthase, alpha subunit
Escherichia coli ECRC101 0.99 OKFHMN_28240 ycgM fumarylacetoacetate hydrolase family protein 0.99 OKFHMN_02675 trpA tryptophan synthase subunit alpha
Escherichia coli ECRC98 0.99 JDDGAC_06270 ycgM fumarylacetoacetate hydrolase family protein 0.99 JDDGAC_05220 trpA tryptophan synthase subunit alpha
Escherichia coli ECRC99 0.99 KEDOAH_25255 ycgM fumarylacetoacetate hydrolase family protein 0.99 KEDOAH_26075 trpA tryptophan synthase subunit alpha
Escherichia fergusonii Becca 0.99 EFB2_02751 putative protein YcgM 0.99 EFB2_02666 Tryptophan synthase alpha chain low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_02511 putative protein YcgM 1.00 OHPLBJKB_02423 Tryptophan synthase alpha chain low > 73
Escherichia coli ECOR27 0.99 NOLOHH_20780 ycgM fumarylacetoacetate hydrolase family protein 1.00 NOLOHH_20335 trpA tryptophan synthase subunit alpha
Escherichia coli ECRC62 0.99 BNILDI_18940 ycgM fumarylacetoacetate hydrolase family protein 1.00 BNILDI_18480 trpA tryptophan synthase subunit alpha
Enterobacter asburiae PDN3 0.88 EX28DRAFT_0760 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) 0.85 EX28DRAFT_0932 tryptophan synthase, alpha chain (EC 4.2.1.20) low > 76
Enterobacter sp. TBS_079 0.88 MPMX20_02705 putative protein YcgM 0.85 MPMX20_02514 Tryptophan synthase alpha chain low > 85
Klebsiella michiganensis M5al 0.88 BWI76_RS17770 isomerase/hydrolase 0.85 BWI76_RS11840 tryptophan synthase subunit alpha low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.88 GFF2814 FIG094199: Fumarylacetoacetate hydrolase 0.85 GFF2726 Tryptophan synthase alpha chain (EC 4.2.1.20) low > 78
Pantoea sp. MT58 0.81 IAI47_08865 fumarylacetoacetate hydrolase family protein 0.73 IAI47_09165 tryptophan synthase subunit alpha low > 76
Erwinia tracheiphila SCR3 0.80 LU632_RS13105 fumarylacetoacetate hydrolase family protein 0.72 LU632_RS12775 trpA tryptophan synthase subunit alpha low > 74
Pectobacterium carotovorum WPP14 0.76 HER17_RS11245 fumarylacetoacetate hydrolase family protein 0.80 HER17_RS10940 tryptophan synthase subunit alpha low > 75
Serratia liquefaciens MT49 0.76 IAI46_14500 fumarylacetoacetate hydrolase family protein 0.78 IAI46_14045 tryptophan synthase subunit alpha low > 86
Dickeya dadantii 3937 0.76 DDA3937_RS11195 fumarylacetoacetate hydrolase family protein 0.79 DDA3937_RS10460 tryptophan synthase subunit alpha low > 74
Dickeya dianthicola ME23 0.75 DZA65_RS11575 fumarylacetoacetate hydrolase family protein 0.79 DZA65_RS10940 tryptophan synthase subunit alpha 0.30 66
Dickeya dianthicola 67-19 0.75 HGI48_RS11230 fumarylacetoacetate hydrolase family protein 0.79 HGI48_RS10460 tryptophan synthase subunit alpha low > 71
Rahnella sp. WP5 0.71 EX31_RS10565 fumarylacetoacetate hydrolase family protein 0.75 EX31_RS09980 tryptophan synthase subunit alpha 0.57 30
Alteromonas macleodii MIT1002 0.54 MIT1002_02584 Ureidoglycolate lyase 0.54 MIT1002_01425 Tryptophan synthase alpha chain
Marinobacter adhaerens HP15 0.50 HP15_2550 fumarylacetoacetate hydrolase family protein 0.29 HP15_1826 tryptophan synthase, alpha subunit
Pseudomonas stutzeri RCH2 0.48 Psest_3871 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) 0.30 Psest_0062 tryptophan synthase, alpha subunit low > 67
Pseudomonas putida KT2440 0.48 PP_5153 putative isomerase/hydrolase 0.31 PP_0082 tryptophan synthase alpha chain low > 96
Pseudomonas fluorescens FW300-N2C3 0.46 AO356_10310 hypothetical protein 0.28 AO356_10910 tryptophan synthase subunit alpha low > 104
Pseudomonas fluorescens FW300-N2E2 0.46 Pf6N2E2_3934 Fumarylacetoacetate hydrolase family protein 0.28 Pf6N2E2_4047 Tryptophan synthase alpha chain (EC 4.2.1.20) low > 103
Pseudomonas fluorescens FW300-N2E3 0.46 AO353_08500 hypothetical protein 0.28 AO353_10705 tryptophan synthase subunit alpha low > 101
Pseudomonas fluorescens FW300-N1B4 0.45 Pf1N1B4_2275 Fumarylacetoacetate hydrolase family protein 0.28 Pf1N1B4_1830 Tryptophan synthase alpha chain (EC 4.2.1.20) low > 87
Pseudomonas simiae WCS417 0.45 PS417_27030 hypothetical protein 0.29 PS417_00180 tryptophan synthase subunit alpha
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS28685 fumarylacetoacetate hydrolase family protein 0.29 PFLU_RS00175 tryptophan synthase subunit alpha low > 109
Pseudomonas fluorescens SBW25 0.45 PFLU_RS28685 fumarylacetoacetate hydrolase family protein 0.29 PFLU_RS00175 tryptophan synthase subunit alpha low > 109
Pseudomonas sp. S08-1 0.45 OH686_11290 Fumarylacetoacetate hydrolase family protein 0.28 OH686_12430 tryptophan synthase, alpha subunit low > 80
Pseudomonas fluorescens GW456-L13 0.45 PfGW456L13_945 Fumarylacetoacetate hydrolase family protein 0.29 PfGW456L13_565 Tryptophan synthase alpha chain (EC 4.2.1.20) low > 87
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_4850 Fumarylacetoacetate (FAA) hydrolase 0.31 Psyr_0033 tryptophan synthase, alpha chain low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_4850 Fumarylacetoacetate (FAA) hydrolase 0.31 Psyr_0033 tryptophan synthase, alpha chain low > 86
Pseudomonas sp. RS175 0.44 PFR28_04840 putative protein YcgM 0.28 PFR28_04716 Tryptophan synthase alpha chain
Acinetobacter radioresistens SK82 0.39 MPMX26_02677 putative protein YcgM 0.27 MPMX26_02611 Tryptophan synthase alpha chain
Pontibacter actiniarum KMM 6156, DSM 19842 0.39 CA264_11935 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 0.26 CA264_05085 tryptophan synthase subunit alpha low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.38 ABZR88_RS01675 fumarylacetoacetate hydrolase family protein 0.24 ABZR88_RS10660 tryptophan synthase subunit alpha
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_2930 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) 0.24 Echvi_2511 tryptophan synthase, alpha subunit
Dyella japonica UNC79MFTsu3.2 0.37 ABZR86_RS11730 fumarylacetoacetate hydrolase family protein 0.29 ABZR86_RS07995 tryptophan synthase subunit alpha
Pedobacter sp. GW460-11-11-14-LB5 0.37 CA265_RS15165 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 0.25 CA265_RS05025 tryptophan synthase, alpha subunit (EC 4.2.1.20) (from data)
Castellaniella sp019104865 MT123 0.37 ABCV34_RS04400 fumarylacetoacetate hydrolase family protein 0.26 ABCV34_RS08430 tryptophan synthase subunit alpha
Ralstonia solanacearum PSI07 0.37 RPSI07_RS22260 FAA hydrolase family protein 0.27 RPSI07_RS14740 tryptophan synthase subunit alpha
Ralstonia solanacearum UW163 0.36 UW163_RS02535 FAA hydrolase family protein 0.27 UW163_RS11150 tryptophan synthase subunit alpha
Ralstonia solanacearum IBSBF1503 0.36 RALBFv3_RS11045 FAA hydrolase family protein 0.27 RALBFv3_RS02575 tryptophan synthase subunit alpha
Rhodanobacter denitrificans FW104-10B01 0.36 LRK54_RS11925 fumarylacetoacetate hydrolase family protein 0.28 LRK54_RS01680 tryptophan synthase, alpha subunit (EC 4.2.1.20) (from data) low > 59
Rhodanobacter denitrificans MT42 0.36 LRK55_RS11650 fumarylacetoacetate hydrolase family protein 0.28 LRK55_RS01460 tryptophan synthase subunit alpha low > 63
Rhodanobacter sp. FW510-T8 0.36 OKGIIK_11960 Fumarylacetoacetate hydrolase 0.28 OKGIIK_04850 trpA tryptophan synthase subunit alpha low > 52
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS06915 fumarylacetoacetate hydrolase family protein 0.27 ABZR87_RS14490 tryptophan synthase subunit alpha low > 80
Ralstonia solanacearum GMI1000 0.35 RS_RS01890 FAA hydrolase family protein 0.27 RS_RS09955 tryptophan synthase subunit alpha low > 80
Caulobacter crescentus NA1000 0.35 CCNA_03682 fumarylpyruvate hydrolase 0.28 CCNA_03657 tryptophan synthase alpha chain low > 66
Sinorhizobium meliloti 1021 0.35 SMc04240 hypothetical protein 0.27 SMc02765 tryptophan synthase subunit alpha low > 103
Cupriavidus basilensis FW507-4G11 0.35 RR42_RS01965 5-carboxymethyl-2-hydroxymuconate isomerase 0.27 RR42_RS14350 tryptophan synthase alpha chain
Caulobacter crescentus NA1000 Δfur 0.35 CCNA_03682 fumarylpyruvate hydrolase 0.28 CCNA_03657 tryptophan synthase alpha chain low > 67
Variovorax sp. SCN45 0.35 GFF1928 Fumarylacetoacetate hydrolase family protein 0.27 GFF3882 Tryptophan synthase alpha chain (EC 4.2.1.20)
Rhodospirillum rubrum S1H 0.35 Rru_A3697 Fumarylacetoacetate (FAA) hydrolase (NCBI) 0.23 Rru_A3428 Tryptophan synthase (NCBI) low > 58
Bacteroides thetaiotaomicron VPI-5482 0.35 BT3883 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (NCBI ptt file) 0.25 BT0527 tryptophan synthase alpha chain (NCBI ptt file) low > 81
Bacteroides stercoris CC31F 0.35 HMPREF1181_RS06960 fumarylacetoacetate hydrolase family protein 0.23 HMPREF1181_RS15350 tryptophan synthase subunit alpha low > 56
Herbaspirillum seropedicae SmR1 0.34 HSERO_RS17860 5-carboxymethyl-2-hydroxymuconate isomerase 0.28 HSERO_RS16470 tryptophan synthase subunit alpha 0.20 67
Variovorax sp. OAS795 0.34 ABID97_RS12395 fumarylacetoacetate hydrolase family protein 0.25 ABID97_RS08425 tryptophan synthase subunit alpha low > 91
Bacteroides ovatus ATCC 8483 0.34 BACOVA_01105 FAH family protein 0.25 BACOVA_03785 tryptophan synthase, alpha subunit low > 94
Dinoroseobacter shibae DFL-12 0.34 Dshi_2538 fumarylacetoacetate (FAA) hydrolase (RefSeq) 0.29 Dshi_0952 tryptophan synthase, alpha subunit (RefSeq)
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS00475 fumarylacetoacetate hydrolase family protein 0.24 HMPREF1058_RS07200 tryptophan synthase subunit alpha low > 67
Azospirillum sp. SherDot2 0.34 MPMX19_00039 Fumarylpyruvate hydrolase 0.26 MPMX19_02737 Tryptophan synthase alpha chain low > 112
Lysobacter sp. OAE881 0.34 ABIE51_RS16580 fumarylacetoacetate hydrolase family protein 0.31 ABIE51_RS08265 tryptophan synthase subunit alpha low > 62
Agrobacterium fabrum C58 0.33 Atu1516 hypothetical protein 0.24 Atu0019 tryptophan synthase alpha subunit
Phocaeicola dorei CL03T12C01 0.33 ABI39_RS08095 fumarylacetoacetate hydrolase family protein 0.24 ABI39_RS21075 tryptophan synthase subunit alpha low > 72
Acidovorax sp. GW101-3H11 0.33 Ac3H11_2308 Fumarylacetoacetate hydrolase family protein 0.26 Ac3H11_1535 Tryptophan synthase alpha chain (EC 4.2.1.20) low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.33 GFF4807 Fumarylacetoacetase (EC 3.7.1.2) 0.27 GFF3354 Tryptophan synthase alpha chain (EC 4.2.1.20) low > 90
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS04845 fumarylacetoacetate hydrolase family protein 0.24 HMPREF1078_RS00120 tryptophan synthase subunit alpha 0.68 41
Shewanella loihica PV-4 0.32 Shew_1535 fumarylacetoacetate (FAA) hydrolase (RefSeq) 0.63 Shew_2256 trpA tryptophan synthase subunit alpha (RefSeq) low > 60
Xanthomonas campestris pv. campestris strain 8004 0.32 Xcc-8004.1278.1 Fumarylacetoacetate hydrolase family protein 0.25 Xcc-8004.1967.1 Tryptophan synthase alpha chain (EC 4.2.1.20) low > 74
Dechlorosoma suillum PS 0.32 Dsui_1428 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase 0.31 Dsui_3191 tryptophan synthase, alpha subunit
Rhizobium sp. OAE497 0.31 ABIE40_RS10920 fumarylacetoacetate hydrolase family protein 0.26 ABIE40_RS19340 tryptophan synthase subunit alpha
Rhodopseudomonas palustris CGA009 0.31 TX73_020685 fumarylacetoacetate hydrolase family protein 0.27 TX73_000365 tryptophan synthase subunit alpha
Bosea sp. OAE506 0.31 ABIE41_RS03580 fumarylacetoacetate hydrolase family protein 0.25 ABIE41_RS03930 tryptophan synthase subunit alpha
Phaeobacter inhibens DSM 17395 0.31 PGA1_c33930 fumarylacetoacetate hydrolase family protein 0.29 PGA1_c04930 tryptophan synthase alpha chain
Burkholderia phytofirmans PsJN 0.31 BPHYT_RS02800 5-carboxymethyl-2-hydroxymuconate isomerase 0.26 BPHYT_RS33865 tryptophan synthase alpha chain low > 109
Methanococcus maripaludis S2 0.30 MMP_RS00825 fumarylacetoacetate hydrolase family protein 0.27 MMP_RS05185 tryptophan synthase subunit alpha
Paraburkholderia sabiae LMG 24235 0.30 QEN71_RS01650 fumarylacetoacetate hydrolase family protein 0.27 QEN71_RS17655 tryptophan synthase subunit alpha low > 153
Brevundimonas sp. GW460-12-10-14-LB2 0.30 A4249_RS12090 fumarylacetoacetate hydrolase family protein 0.25 A4249_RS11320 tryptophan synthase subunit alpha
Methanococcus maripaludis JJ 0.30 MMJJ_RS04665 fumarylacetoacetate hydrolase family protein 0.26 MMJJ_RS09195 tryptophan synthase subunit alpha
Sphingomonas koreensis DSMZ 15582 0.30 Ga0059261_0508 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) 0.28 Ga0059261_0239 tryptophan synthase, alpha chain (EC 4.2.1.20) low > 68
Paraburkholderia bryophila 376MFSha3.1 0.30 H281DRAFT_01971 fumarylpyruvate hydrolase 0.27 H281DRAFT_06065 tryptophan synthase, alpha chain low > 103
Paraburkholderia graminis OAS925 0.29 ABIE53_000698 fumarylpyruvate hydrolase 0.28 ABIE53_004811 tryptophan synthase alpha chain low > 113
Shewanella amazonensis SB2B 0.28 Sama_1093 fumarylacetoacetate (FAA) hydrolase (RefSeq) 0.58 Sama_2134 trpA tryptophan synthase subunit alpha (RefSeq) low > 62
Vibrio cholerae E7946 ATCC 55056 0.27 CSW01_19130 FAA hydrolase family protein 0.61 CSW01_05925 tryptophan synthase subunit alpha low > 62

Not shown: 1 genomes with orthologs for b1180 only; 8 genomes with orthologs for b1260 only