Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Agrobacterium fabrum C58 | Atu0337 | | proteinase IV | insig. | 100 | 100 |
o | Sinorhizobium meliloti 1021 | SMc01135 | | protease IV transmembrane protein | insig. | 66 | 99 |
o | Rhizobium sp. OAE497 | ABIE40_RS01840 | | signal peptide peptidase SppA | insig. | 66 | 99 |
o | Bosea sp. OAE506 | ABIE41_RS00300 | | signal peptide peptidase SppA | sig. | 41 | 98 |
o | Rhodopseudomonas palustris CGA009 | TX73_000340 | | signal peptide peptidase SppA | insig. | 43 | 83 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_1703 | | signal peptide peptidase SppA, 36K type (RefSeq) | sig. | 35 | 79 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU3149 | sppA | signal peptide peptidase SppA, 36K type (TIGR) | cofit | 36 | 71 |
| Synechococcus elongatus PCC 7942 | Synpcc7942_1916 | sppA | signal peptide peptidase A. Serine peptidase. MEROPS family S49 | sig. | 38 | 66 |
o | Methanococcus maripaludis JJ | MMJJ_RS08835 | | signal peptide peptidase SppA | insig. | 32 | 82 |
o | Methanococcus maripaludis S2 | MMP_RS05530 | | signal peptide peptidase SppA | insig. | 32 | 82 |
| Bacteroides ovatus ATCC 8483 | BACOVA_02940 | | signal peptide peptidase SppA, 67K type | strong | 31 | 63 |
| Bacteroides thetaiotaomicron VPI-5482 | BT1879 | | protease IV (NCBI ptt file) | sig. | 30 | 63 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2783 | | signal peptide peptidase SppA, 67K type | strong | 34 | 62 |
| Bacteroides stercoris CC31F | HMPREF1181_RS07630 | | signal peptide peptidase SppA | sig. | 34 | 57 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_3163 | | signal peptide peptidase SppA, 36K type (RefSeq) | insig. | 36 | 63 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS05290 | | signal peptide peptidase SppA | cofit | 34 | 56 |
| Phocaeicola dorei CL03T12C01 | ABI39_RS07925 | | signal peptide peptidase SppA | insig. | 34 | 57 |
| Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS12895 | | signal peptide peptidase SppA | sig. | 34 | 57 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_1351 | | signal peptide peptidase SppA, 67K type | strong | 35 | 51 |
| Fusobacterium nucleatum SB010 | HUW76_05945 | | signal peptide peptidase SppA | cofit | 29 | 71 |
| Fusobacterium nucleatum SB010 | HUW76_03895 | | signal peptide peptidase SppA | strong | 29 | 68 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_02220 | | signal peptide peptidase SppA | cofit | 33 | 63 |
| Pseudomonas syringae pv. syringae B728a | Psyr_1641 | | Peptidase S49, SppA | insig. | 30 | 92 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1641 | | Peptidase S49, SppA | insig. | 30 | 92 |
| Azospirillum sp. SherDot2 | MPMX19_00798 | | Protease 4 | insig. | 29 | 76 |
| Escherichia fergusonii Becca | EFB2_02228 | | Protease 4 | insig. | 35 | 51 |
| Escherichia coli ECOR27 | NOLOHH_17325 | sppA | signal peptide peptidase SppA | no data | 35 | 51 |
| Escherichia coli ECOR38 | HEPCGN_05185 | sppA | signal peptide peptidase SppA | cofit | 35 | 51 |
| Escherichia coli ECRC101 | OKFHMN_26815 | sppA | signal peptide peptidase SppA | insig. | 35 | 51 |
| Escherichia coli ECRC101 | MCAODC_18595 | sppA | signal peptide peptidase SppA | insig. | 35 | 51 |
| Escherichia coli ECRC102 | NIAGMN_01250 | sppA | signal peptide peptidase SppA | no data | 35 | 51 |
| Escherichia coli ECRC62 | BNILDI_16110 | sppA | signal peptide peptidase SppA | insig. | 35 | 51 |
| Escherichia coli ECRC98 | JDDGAC_01390 | sppA | signal peptide peptidase SppA | no data | 35 | 51 |
| Escherichia coli ECRC99 | KEDOAH_01295 | sppA | signal peptide peptidase SppA | no data | 35 | 51 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01966 | | Protease 4 | insig. | 35 | 51 |
| Escherichia coli Nissle 1917 | ECOLIN_RS09855 | | signal peptide peptidase SppA | no data | 35 | 51 |
| Escherichia coli BL21 | ECD_01735 | | protease IV (signal peptide peptidase) | insig. | 35 | 51 |
| Escherichia coli BW25113 | b1766 | sppA | protease IV (signal peptide peptidase) (NCBI) | sig. | 35 | 51 |
| Alteromonas macleodii MIT1002 | MIT1002_01840 | | Protease 4 | strong | 35 | 54 |
| Pantoea sp. MT58 | IAI47_08970 | | signal peptide peptidase SppA | insig. | 32 | 70 |
| Enterobacter asburiae PDN3 | EX28DRAFT_1767 | | signal peptide peptidase SppA, 67K type | cofit | 34 | 51 |
| Azospirillum brasilense Sp245 | AZOBR_RS10750 | | protease IV | insig. | 31 | 63 |
| Ralstonia solanacearum PSI07 | RPSI07_RS19070 | | S49 family peptidase | insig. | 30 | 82 |
| Klebsiella michiganensis M5al | BWI76_RS11585 | | signal peptide peptidase A | sig. | 34 | 51 |
| Shewanella loihica PV-4 | Shew_1941 | | signal peptide peptidase SppA, 67K type (RefSeq) | sig. | 34 | 52 |
| Pseudomonas putida KT2440 | PP_1908 | | putative Peptidase | insig. | 31 | 86 |
| Erwinia tracheiphila SCR3 | LU632_RS12970 | sppA | signal peptide peptidase SppA | cofit | 31 | 62 |
| Serratia liquefaciens MT49 | IAI46_14325 | | signal peptide peptidase SppA | insig. | 34 | 51 |
| Ralstonia solanacearum GMI1000 | RS_RS05170 | | S49 family peptidase | insig. | 30 | 82 |
| Pseudomonas sp. S08-1 | OH686_22105 | | Periplasmic serine (ClpP class) | cofit | 31 | 77 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS09430 | | peptidase S49 | sig. | 28 | 75 |
| Shewanella amazonensis SB2B | Sama_1723 | | signal peptide peptidase SppA, 67K type (RefSeq) | sig. | 33 | 52 |
| Mycobacterium tuberculosis H37Rv | Rv0724 | | Possible protease IV SppA (endopeptidase IV) (signal peptide peptidase) | insig. | 31 | 63 |
| Enterobacter sp. TBS_079 | MPMX20_01850 | | Protease 4 | strong | 33 | 51 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3483 | | Signal peptide peptidase SppA (EC 3.4.21.-) | insig. | 34 | 51 |
| Lysobacter sp. OAE881 | ABIE51_RS02175 | | signal peptide peptidase SppA | strong | 34 | 55 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS12520 | | signal peptide peptidase SppA | strong | 34 | 63 |
| Rahnella sp. WP5 | EX31_RS06305 | | signal peptide peptidase SppA | insig. | 30 | 61 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_1578 | | signal peptide peptidase SppA, 67K type | strong | 34 | 55 |
| Shewanella oneidensis MR-1 | SO2420 | sppA | signal peptide peptidase SppA, 67K type (NCBI ptt file) | strong | 33 | 55 |
| Pseudomonas stutzeri RCH2 | Psest_1682 | | Periplasmic serine proteases (ClpP class) | strong | 31 | 76 |
| Dickeya dadantii 3937 | DDA3937_RS10290 | | signal peptide peptidase SppA | cofit | 32 | 51 |
| Rhodanobacter denitrificans MT42 | LRK55_RS10795 | | signal peptide peptidase SppA | cofit | 35 | 55 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS11090 | | signal peptide peptidase SppA | cofit | 35 | 55 |
| Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS01460 | | signal peptide peptidase SppA | cofit | 35 | 63 |
| Dickeya dianthicola ME23 | DZA65_RS10775 | | signal peptide peptidase SppA | insig. | 32 | 51 |
| Dickeya dianthicola 67-19 | HGI48_RS10300 | | signal peptide peptidase SppA | insig. | 32 | 51 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_09950 | | signal peptide peptidase SppA | insig. | 32 | 60 |
| Pectobacterium carotovorum WPP14 | HER17_RS11105 | | signal peptide peptidase SppA | insig. | 32 | 51 |
| Shewanella sp. ANA-3 | Shewana3_1964 | | signal peptide peptidase SppA, 67K type (RefSeq) | strong | 31 | 62 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.4759.1 | | protease IV | strong | 27 | 70 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS14140 | | peptidase S49 | insig. | 29 | 74 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS14390 | | S49 family peptidase | insig. | 28 | 82 |
| Ralstonia solanacearum UW163 | UW163_RS11855 | | S49 family peptidase | insig. | 28 | 82 |
| Rhizobium sp. OAE497 | ABIE40_RS05390 | | S49 family peptidase | insig. | 33 | 54 |
| Azospirillum sp. SherDot2 | MPMX19_04409 | | hypothetical protein | insig. | 31 | 65 |
| Agrobacterium fabrum C58 | Atu0637 | | proteinase sohB | sig. | 34 | 56 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS13925 | | signal peptide peptidase SppA | no data | 30 | 70 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_2099 | | Periplasmic serine proteases (ClpP class) | insig. | 29 | 92 |
| Rhodanobacter sp. FW510-T8 | OKGIIK_12785 | sppA | signal peptide peptidase SppA | insig. | 33 | 54 |
| Caulobacter crescentus NA1000 | CCNA_00976 | | signal peptide peptidase A | strong | 35 | 59 |
| Caulobacter crescentus NA1000 Δfur | CCNA_00976 | | signal peptide peptidase A | cofit | 35 | 59 |
| Sinorhizobium meliloti 1021 | SMc00857 | | protease | strong | 33 | 54 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS10105 | | S49 family peptidase | insig. | 29 | 81 |
| Pseudomonas simiae WCS417 | PS417_21470 | | peptidase S49 | insig. | 28 | 92 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS04415 | | signal peptide peptidase SppA | strong | 27 | 69 |
| Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_457 | | Periplasmic serine proteases (ClpP class) | insig. | 30 | 78 |
| Marinobacter adhaerens HP15 | HP15_2219 | | family S49 unassigned peptidase | insig. | 26 | 76 |
| Pseudomonas fluorescens SBW25 | PFLU_RS23085 | | S49 family peptidase | cofit | 28 | 86 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS23085 | | S49 family peptidase | insig. | 28 | 86 |
| Magnetospirillum magneticum AMB-1 | AMB_RS08065 | | serine protease | cofit | 33 | 60 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_20135 | | peptidase S49 | strong | 28 | 76 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5946 | | Periplasmic serine proteases (ClpP class) | insig. | 27 | 92 |
| Rhodospirillum rubrum S1H | Rru_A2621 | | Peptidase S49 (NCBI) | insig. | 29 | 67 |
| Enterobacter sp. TBS_079 | MPMX20_02504 | | putative protease SohB | insig. | 30 | 63 |
| Azospirillum brasilense Sp245 | AZOBR_RS12180 | | peptidase S49 | insig. | 29 | 69 |
| Pseudomonas putida KT2440 | PP_3878 | | putative Phage minor capsid protein C | insig. | 29 | 54 |
| Pseudomonas fluorescens FW300-N2E3 | AO353_01395 | | peptidase S49 | sig. | 29 | 76 |
| Pseudomonas sp. RS175 | PFR28_03016 | | hypothetical protein | sig. | 27 | 76 |
| Rhodopseudomonas palustris CGA009 | TX73_005360 | | S49 family peptidase | insig. | 34 | 56 |