| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Shewanella oneidensis MR-1 | SO4637 | | DNA-binding response regulator (NCBI ptt file) | insig. | 100 | 100 |
| o | Pseudomonas stutzeri RCH2 | Psest_3465 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 43 | 99 |
| o | Pseudomonas sp. S08-1 | OH686_17340 | | DNA-binding response regulator ColR | insig. | 42 | 99 |
| o | Pseudomonas aeruginosa MRSN321 | PFGADD_04581 | colR | response regulator transcription factor ColR | cofit | 42 | 99 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_02195 | | DNA-binding response regulator | sig. | 42 | 99 |
| o | Pseudomonas aeruginosa PUPa3 | NPBIFN_04640 | colR | response regulator transcription factor ColR | insig. | 42 | 99 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_18415 | | XRE family transcriptional regulator | strong | 42 | 99 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5609 | | DNA-binding response regulator ColR | strong | 42 | 99 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS24430 | | response regulator transcription factor | insig. | 41 | 99 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS24430 | | response regulator transcription factor | sig. | 41 | 99 |
| o | Pseudomonas sp. DMC3 | GFF5074 | | Transcriptional activator protein CzcR | cofit | 41 | 99 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04707 | | Transcriptional activator protein CzcR | cofit | 41 | 99 |
| o | Pseudomonas simiae WCS417 | PS417_22780 | | XRE family transcriptional regulator | strong | 41 | 99 |
| o | Pseudomonas fluorescens FW300-N2E3 | AO353_04020 | | XRE family transcriptional regulator | strong | 41 | 99 |
| | Pseudomonas sp. RS175 | PFR28_03335 | | Transcriptional activator protein CzcR | strong | 42 | 99 |
| o | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1767 | | DNA-binding response regulator ColR | strong | 41 | 99 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_724 | | DNA-binding response regulator ColR | strong | 41 | 99 |
| | Pseudomonas protegens RBAN4 | FABNJH_24455 | colR | two-component system response regulator ColR | insig. | 41 | 99 |
| o | Pseudomonas orientalis W4I3 | QF045_RS24960 | | two-component system response regulator ColR | cofit | 41 | 99 |
| | Pseudomonas sp. BP01 | JOY50_RS14980 | colR | two-component system response regulator ColR | insig. | 40 | 99 |
| | Pseudomonas putida KT2440 | PP_0901 | | DNA-binding response regulator | strong | 40 | 99 |
| | Pseudomonas sp. SVBP6 | COO64_RS12030 | colR | two-component system response regulator ColR | insig. | 41 | 99 |
| | Pseudomonas segetis P6 | ACVTMO_RS18790 | | response regulator transcription factor | strong | 41 | 99 |
| o | Pseudomonas syringae pv. syringae B728a | Psyr_4070 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | strong | 40 | 99 |
| o | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_4070 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | insig. | 40 | 99 |
| | Lysobacter sp. OAE881 | ABIE51_RS05295 | | response regulator transcription factor | strong | 42 | 98 |
| o | Rhodanobacter denitrificans MT42 | LRK55_RS11745 | | response regulator transcription factor | no data | 40 | 100 |
| o | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS12010 | | response regulator transcription factor | strong | 40 | 100 |
| o | Rhodanobacter sp. FW510-T8 | OKGIIK_11850 | ompR | DNA-binding response regulator | no data | 40 | 100 |
| o | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS16525 | | response regulator transcription factor | no data | 40 | 100 |
| o | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS11615 | | response regulator transcription factor | no data | 40 | 100 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_10950 | ompR | DNA-binding response regulator | insig. | 42 | 98 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS05835 | | response regulator transcription factor | cofit | 42 | 98 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.4286.1 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 41 | 98 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS03860 | | response regulator transcription factor | cofit | 42 | 98 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS04090 | | response regulator transcription factor | sig. | 42 | 98 |
| | Pseudomonas aeruginosa MRSN321 | PFGADD_01891 | cprR | cationic peptide response regulator transcription factor CprR | insig. | 40 | 99 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_15645 | | cationic peptide response regulator transcription factor CprR | insig. | 40 | 99 |
| | Pseudomonas aeruginosa PUPa3 | NPBIFN_01928 | cprR | cationic peptide response regulator transcription factor CprR | insig. | 40 | 99 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1335.1 | | Two-component system regulatory protein | no data | 39 | 99 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.3867.1 | | Two-component system regulatory protein | insig. | 38 | 99 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0632 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | insig. | 41 | 99 |
| | Lysobacter sp. OAE881 | ABIE51_RS16515 | | response regulator transcription factor | no data | 39 | 99 |
| | Lysobacter sp. OAE881 | ABIE51_RS17870 | | response regulator transcription factor | insig. | 40 | 98 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_2375 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | insig. | 41 | 99 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2375 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | insig. | 41 | 99 |
| o | Shewanella loihica PV-4 | Shew_3317 | | two component transcriptional regulator (RefSeq) | insig. | 40 | 99 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_15065 | | XRE family transcriptional regulator | strong | 40 | 99 |
| | Pseudomonas protegens RBAN4 | FABNJH_25725 | | DNA-binding response regulator | insig. | 39 | 99 |
| | Lysobacter sp. OAE881 | ABIE51_RS08445 | | response regulator transcription factor | insig. | 38 | 100 |
| o | Alteromonas macleodii MIT1002 | MIT1002_00641 | | Transcriptional regulatory protein QseB | insig. | 39 | 98 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS19100 | | response regulator transcription factor | insig. | 37 | 99 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS18610 | | response regulator transcription factor | sig. | 37 | 99 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS09005 | | response regulator transcription factor | insig. | 37 | 99 |
| | Lysobacter sp. OAE881 | ABIE51_RS03740 | | response regulator transcription factor | cofit | 37 | 98 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_06035 | ompR | DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain | insig. | 36 | 99 |
| | Acinetobacter baumannii LAC-4 | RR41_RS06610 | | response regulator transcription factor | insig. | 37 | 98 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_11110 | ompR | DNA-binding response regulator | strong | 36 | 99 |
| | Shewanella oneidensis MR-1 | SO4623 | | DNA-binding response regulator (NCBI ptt file) | insig. | 40 | 99 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS04005 | | response regulator transcription factor | strong | 36 | 99 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS04235 | | response regulator transcription factor | strong | 36 | 99 |
| | Shewanella sp. ANA-3 | Shewana3_4007 | | two component transcriptional regulator (RefSeq) | insig. | 39 | 99 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3091 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | insig. | 35 | 99 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3091 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | sig. | 35 | 99 |
| | Shewanella amazonensis SB2B | Sama_0146 | | response regulator receiver protein (RefSeq) | insig. | 35 | 100 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS17060 | | heavy metal response regulator transcription factor | insig. | 34 | 99 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS17160 | | heavy metal response regulator transcription factor | insig. | 35 | 99 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS17690 | | heavy metal response regulator transcription factor | insig. | 35 | 99 |
| | Caulobacter crescentus NA1000 | CCNA_02845 | | two-component response regulator | strong | 34 | 100 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02845 | | two-component response regulator | cofit | 34 | 100 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01441 | | two component heavy metal response transcriptional regulator, winged helix family | insig. | 33 | 99 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS17605 | | response regulator transcription factor | sig. | 33 | 99 |
| | Mycobacterium tuberculosis H37Rv | Rv0981 | | Mycobacterial persistence regulator MRPA (two component response transcriptional regulatory protein) | insig. | 32 | 98 |
| | Mycobacterium tuberculosis H37Rv | Rv0757 | | Possible two component system response transcriptional positive regulator PhoP | sig. | 36 | 99 |
| | Alteromonas macleodii MIT1002 | MIT1002_03097 | | Transcriptional activator protein CopR | insig. | 34 | 99 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS29120 | | transcriptional regulator | insig. | 33 | 99 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS12420 | | transcriptional regulator | insig. | 34 | 100 |
| | Variovorax sp. SCN45 | GFF11 | | Two-component transcriptional response regulator, OmpR family | insig. | 33 | 99 |
| | Rhizobium sp. OAE497 | ABIE40_RS05700 | | response regulator transcription factor | insig. | 34 | 98 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1404 | | two component transcriptional regulator, winged helix family | no data | 33 | 99 |
| | Mycobacterium tuberculosis H37Rv | Rv0602c | | Two component DNA binding transcriptional regulatory protein TcrA | insig. | 34 | 99 |
| | Paraburkholderia graminis OAS925 | ABIE53_005209 | | two-component system copper resistance phosphate regulon response regulator CusR | insig. | 33 | 99 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS21280 | | DNA-binding response regulator | insig. | 33 | 99 |
| | Ralstonia solanacearum UW163 | UW163_RS22425 | | DNA-binding response regulator | insig. | 33 | 99 |
| | Mycobacterium tuberculosis H37Rv | Rv1033c | | Two component transcriptional regulator TrcR | insig. | 35 | 100 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_02865 | | transcriptional regulator | strong | 33 | 100 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2397 | | Two-component system response regulator QseB | sig. | 33 | 100 |
| | Pseudomonas sp. BP01 | JOY50_RS18885 | | response regulator transcription factor | insig. | 34 | 100 |
| | Ralstonia solanacearum GMI1000 | RS_RS20255 | | DNA-binding response regulator | insig. | 33 | 99 |
| | Pseudomonas sp. RS175 | PFR28_01030 | | Transcriptional regulatory protein QseB | insig. | 33 | 100 |
| | Acinetobacter baumannii LAC-4 | RR41_RS06150 | | response regulator transcription factor | insig. | 33 | 99 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_2299 | | Two-component system response regulator QseB | sig. | 33 | 100 |
| | Pseudomonas putida KT2440 | PP_4225 | | two component system DNA-binding transcriptional activator QseB | sig. | 35 | 100 |
| | Pseudomonas sp. SVBP6 | COO64_RS16580 | | heavy metal response regulator transcription factor | insig. | 34 | 99 |
| | Rhodopseudomonas palustris CGA009 | TX73_009945 | | response regulator transcription factor | insig. | 33 | 98 |
| | Pseudomonas sp. DMC3 | GFF4547 | | Transcriptional regulatory protein QseB | cofit | 33 | 100 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS21725 | | heavy metal response regulator transcription factor | insig. | 33 | 99 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS32640 | | heavy metal response regulator transcription factor | insig. | 33 | 99 |
| | Agrobacterium fabrum C58 | Atu0629 | | two component response regulator | insig. | 35 | 99 |
| | Ralstonia solanacearum GMI1000 | RS_RS19510 | | DNA-binding response regulator | sig. | 31 | 99 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS01875 | | DNA-binding response regulator | insig. | 31 | 99 |
| | Variovorax sp. SCN45 | GFF4069 | | DNA-binding heavy metal response regulator | insig. | 31 | 99 |
| | Sinorhizobium meliloti 1021 | SMc02366 | | transcriptional regulator | strong | 33 | 98 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_19370 | | transcriptional regulator | strong | 33 | 100 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS00075 | | transcriptional regulator | insig. | 32 | 98 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS05740 | | response regulator transcription factor | no data | 36 | 99 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS05985 | | response regulator transcription factor | cofit | 36 | 99 |
| | Pseudomonas sp. SVBP6 | COO64_RS18770 | | response regulator transcription factor | insig. | 34 | 100 |
| | Pseudomonas protegens RBAN4 | FABNJH_21575 | | DNA-binding response regulator | insig. | 33 | 100 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS15305 | | heavy metal response regulator transcription factor | insig. | 33 | 99 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_208 | | Two-component system response regulator QseB | sig. | 32 | 100 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS25955 | | transcriptional regulator | insig. | 32 | 99 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS17390 | | response regulator transcription factor | no data | 36 | 99 |
| | Bifidobacterium breve UCC2003 | BBR_RS17455 | | DNA-binding response regulator | strong | 34 | 90 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3273 | | Putative two-component system response regulator YedW | insig. | 34 | 99 |
| | Agrobacterium fabrum C58 | Atu0978 | | two component response regulator | strong | 33 | 98 |
| | Azospirillum sp. SherDot2 | MPMX19_00794 | | Transcriptional activator protein CopR | sig. | 33 | 99 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_4800 | | Heavy metal response regulator | insig. | 32 | 99 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_4800 | | Heavy metal response regulator | insig. | 32 | 99 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_28575 | | transcriptional regulator | insig. | 31 | 99 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_00635 | ompR | DNA-binding response regulator | no data | 36 | 99 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3235 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | insig. | 36 | 99 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS31535 | | transcriptional regulator | insig. | 31 | 99 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.5008.1 | | Two-component system regulatory protein | no data | 34 | 99 |
| | Dechlorosoma suillum PS | Dsui_1617 | | response regulator with CheY-like receiver domain and winged-helix DNA-binding domain | no data | 34 | 100 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS18360 | | response regulator transcription factor | strong | 35 | 99 |
| | Lysobacter sp. OAE881 | ABIE51_RS03940 | | response regulator transcription factor | strong | 34 | 99 |
| | Rhodospirillum rubrum S1H | Rru_A0603 | | Two component Transcriptional regulator, Winged helix family (NCBI) | cofit | 33 | 98 |
| | Acinetobacter baumannii LAC-4 | RR41_RS06560 | | heavy metal response regulator transcription factor | insig. | 30 | 99 |
| | Pseudomonas sp. BP01 | JOY50_RS14720 | | heavy metal response regulator transcription factor | insig. | 32 | 99 |
| | Pseudomonas putida KT2440 | PP_1438 | | response regulator | insig. | 32 | 99 |
| | Dechlorosoma suillum PS | Dsui_2644 | | heavy metal response regulator | cofit | 33 | 99 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1469 | | Transcriptional regulatory protein basR/pmrA | cofit | 32 | 100 |
| | Rhizobium sp. OAE497 | ABIE40_RS24970 | | winged helix-turn-helix domain-containing protein | insig. | 32 | 99 |
| | Xanthobacter sp. DMC5 | GFF3127 | | Transcriptional regulatory protein CusR | no data | 32 | 98 |
| | Pseudomonas putida KT2440 | PP_0047 | | response regulator | insig. | 32 | 99 |
| | Pseudomonas simiae WCS417 | PS417_18460 | | transcriptional regulator | sig. | 32 | 99 |
| | Pseudomonas stutzeri RCH2 | Psest_1602 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | insig. | 34 | 100 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS06935 | | phosphate regulon transcriptional regulatory protein PhoB | insig. | 33 | 98 |
| | Alteromonas macleodii MIT1002 | MIT1002_01421 | | Transcriptional regulatory protein PhoP | insig. | 32 | 99 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS21485 | | response regulator | insig. | 31 | 100 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS21485 | | response regulator | sig. | 31 | 100 |
| | Fusobacterium nucleatum SB010 | HUW76_07205 | | response regulator transcription factor | strong | 34 | 99 |
| | Shewanella loihica PV-4 | Shew_2695 | | two component transcriptional regulator (RefSeq) | insig. | 34 | 100 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS10810 | | response regulator transcription factor | insig. | 32 | 99 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS02355 | | DNA-binding response regulator | insig. | 32 | 99 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS20435 | | heavy metal response regulator transcription factor | insig. | 31 | 99 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS20435 | | heavy metal response regulator transcription factor | insig. | 31 | 99 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03921 | | Transcriptional activator protein CzcR | cofit | 32 | 99 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS06340 | | response regulator transcription factor | strong | 31 | 98 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS30960 | | transcriptional regulator | strong | 29 | 98 |
| | Marinobacter adhaerens HP15 | HP15_2937 | | two component transcriptional regulator, winged helix family | insig. | 33 | 99 |
| | Pseudomonas protegens RBAN4 | FABNJH_26360 | | DNA-binding response regulator | insig. | 31 | 99 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_13855 | pmrA | two-component system response regulator PmrA | cofit | 35 | 99 |
| | Erwinia tracheiphila SCR3 | LU632_RS21175 | pmrA | two-component system response regulator PmrA | insig. | 35 | 99 |
| | Pseudomonas sp. S08-1 | OH686_22680 | | Copper-sensing two-component system response regulator CusR | strong | 33 | 99 |
| | Fusobacterium nucleatum SB010 | HUW76_03950 | | response regulator transcription factor | strong | 33 | 98 |
| | Pseudomonas simiae WCS417 | PS417_19520 | | transcriptional regulator | insig. | 31 | 100 |
| | Paraburkholderia graminis OAS925 | ABIE53_001506 | | two-component system copper resistance phosphate regulon response regulator CusR | insig. | 33 | 98 |
| | Pseudomonas sp. RS175 | PFR28_03578 | | Transcriptional activator protein CzcR | sig. | 33 | 99 |
| | Pseudomonas orientalis W4I3 | QF045_RS20600 | | heavy metal response regulator transcription factor | insig. | 31 | 99 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS14470 | | phosphate regulon transcriptional regulator PhoB | insig. | 33 | 98 |
| | Azospirillum brasilense Sp245 | AZOBR_RS10800 | | XRE family transcriptional regulator | sig. | 33 | 99 |
| | Pseudomonas segetis P6 | ACVTMO_RS00395 | | heavy metal response regulator transcription factor | insig. | 32 | 99 |
| | Erwinia amylovora T8 | OLJFJH_07175 | | two-component system response regulator PmrA | insig. | 33 | 99 |
| | Enterobacter sp. TBS_079 | MPMX20_04087 | | Transcriptional regulatory protein BasR | strong | 36 | 99 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS12650 | | response regulator | insig. | 34 | 99 |
| | Sphingobium sp. HT1-2 | GFF2992 | | Two-component transcriptional response regulator SMc02366, LuxR family | cofit | 33 | 99 |
| | Variovorax sp. SCN45 | GFF5812 | | DNA-binding heavy metal response regulator | insig. | 32 | 98 |
| | Pseudomonas sp. RS175 | PFR28_02328 | | Transcriptional regulatory protein QseB | sig. | 32 | 98 |
| | Bosea sp. OAE506 | ABIE41_RS21440 | | response regulator transcription factor | insig. | 32 | 98 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1663 | | DNA-binding heavy metal response regulator | insig. | 33 | 99 |
| | Rhodospirillum rubrum S1H | Rru_A2913 | | Two component Transcriptional regulator, Winged helix family (NCBI) | insig. | 31 | 99 |
| | Pseudomonas protegens RBAN4 | FABNJH_01055 | czcR | Transcriptional activator protein CzcR | insig. | 30 | 99 |
| | Caulobacter crescentus NA1000 | CCNA_00296 | | phosphate regulon response regulator PhoB | strong | 36 | 98 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00296 | | phosphate regulon response regulator PhoB | cofit | 36 | 98 |
| | Sphingobium sp. HT1-2 | GFF3652 | | Two-component transcriptional response regulator, OmpR family | cofit | 31 | 100 |
| | Xanthobacter sp. DMC5 | GFF2342 | | Phosphate regulon transcriptional regulatory protein PhoB | no data | 31 | 98 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2498 | | Response regulator receiver:Transcriptional regulatory protein, C- terminal | strong | 31 | 98 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_07315 | | DNA-binding response regulator | insig. | 30 | 100 |
| | Pseudomonas sp. DMC3 | GFF4241 | | Transcriptional activator protein CzcR | cofit | 29 | 99 |
| | Agrobacterium fabrum C58 | Atu4712 | | two component response regulator | insig. | 34 | 99 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS03230 | | heavy metal response regulator transcription factor | insig. | 33 | 99 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS20860 | | DNA-binding response regulator | insig. | 32 | 99 |
| | Ralstonia solanacearum UW163 | UW163_RS21995 | | DNA-binding response regulator | insig. | 32 | 99 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3374 | | Heavy metal response regulator | insig. | 31 | 98 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3374 | | Heavy metal response regulator | insig. | 31 | 98 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_15395 | | transcriptional regulator | sig. | 33 | 99 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1873 | | two component transcriptional regulator, winged helix family | insig. | 30 | 97 |
| | Azospirillum sp. SherDot2 | MPMX19_06359 | | Transcriptional activator protein CopR | no data | 31 | 99 |
| | Azospirillum sp. SherDot2 | MPMX19_06441 | | Transcriptional activator protein CopR | no data | 31 | 99 |
| | Marinobacter adhaerens HP15 | HP15_3484 | | DNA-binding response regulator | no data | 30 | 99 |
| | Variovorax sp. SCN45 | GFF4042 | | Copper-sensing two-component system response regulator CusR | insig. | 29 | 99 |
| | Paraburkholderia graminis OAS925 | ABIE53_005703 | | two-component system copper resistance phosphate regulon response regulator CusR | sig. | 29 | 99 |
| | Pseudomonas sp. BP01 | JOY50_RS19270 | | heavy metal response regulator transcription factor | insig. | 32 | 99 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01736 | | two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR | insig. | 32 | 98 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1539 | | Two-component system response regulator QseB | insig. | 32 | 98 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04104 | | Transcriptional regulatory protein QseB | cofit | 31 | 100 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS03480 | | heavy metal response regulator transcription factor | insig. | 31 | 99 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS03480 | | heavy metal response regulator transcription factor | insig. | 31 | 99 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS04765 | | heavy metal response regulator transcription factor | insig. | 33 | 99 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS04765 | | heavy metal response regulator transcription factor | insig. | 33 | 99 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_17205 | | transcriptional regulator | insig. | 33 | 99 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5366 | | DNA-binding heavy metal response regulator | insig. | 33 | 99 |
| | Escherichia fergusonii Becca | EFB2_04469 | | Transcriptional regulatory protein BasR | insig. | 31 | 100 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS23805 | | two-component system response regulator BasR | sig. | 31 | 100 |
| | Shewanella amazonensis SB2B | Sama_3303 | | response regulator receiver protein (RefSeq) | insig. | 34 | 99 |
| | Pseudomonas orientalis W4I3 | QF045_RS07685 | | heavy metal response regulator transcription factor | cofit | 33 | 99 |
| | Pseudomonas protegens RBAN4 | FABNJH_25495 | ompR | DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain | insig. | 32 | 99 |
| | Acinetobacter radioresistens SK82 | MPMX26_02034 | | Transcriptional regulatory protein QseB | no data | 32 | 99 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4017 | | DNA-binding heavy metal response regulator | insig. | 32 | 99 |
| | Pseudomonas sp. DMC3 | GFF3603 | | Transcriptional regulatory protein QseB | cofit | 32 | 98 |
| | Pseudomonas simiae WCS417 | PS417_03365 | | transcriptional regulator | insig. | 31 | 99 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS01550 | | two-component system response regulator RppA | no data | 33 | 100 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_23845 | | XRE family transcriptional regulator | insig. | 32 | 98 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01140 | | Transcriptional activator protein CzcR | insig. | 33 | 99 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS16110 | | two-component system response regulator RppA | insig. | 32 | 100 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_25485 | | XRE family transcriptional regulator | insig. | 32 | 98 |
| | Rhizobium sp. OAE497 | ABIE40_RS30390 | | response regulator transcription factor | insig. | 32 | 99 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1663 | | heavy metal response regulator | insig. | 31 | 99 |
| | Pseudomonas simiae WCS417 | PS417_04690 | | transcriptional regulator | strong | 33 | 99 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_14885 | ompR | DNA-binding response regulator | insig. | 31 | 98 |
| | Pseudomonas putida KT2440 | PP_2713 | | DNA-binding response regulator | sig. | 33 | 98 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS04815 | | response regulator transcription factor | insig. | 33 | 100 |
| | Variovorax sp. SCN45 | GFF5388 | | Two-component response regulatory protein BP2547 | insig. | 32 | 98 |
| | Escherichia coli ECRC100 | OKFHMN_12570 | basR | two-component system response regulator BasR | cofit | 31 | 100 |
| | Escherichia coli BW25113 | b4113 | basR | DNA-binding response regulator in two-component regulatory system with BasS (NCBI) | sig. | 31 | 100 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS07810 | | response regulator transcription factor | insig. | 31 | 98 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS08060 | | response regulator transcription factor | insig. | 31 | 98 |
| | Klebsiella michiganensis M5al | BWI76_RS08795 | | DNA-binding response regulator | sig. | 30 | 100 |
| | Rahnella sp. WP5 | EX31_RS08605 | | two-component system response regulator PmrA | insig. | 34 | 99 |
| | Bifidobacterium breve UCC2003 | BBR_RS14235 | | DNA-binding response regulator | no data | 32 | 99 |
| | Shewanella loihica PV-4 | Shew_0097 | | two component transcriptional regulator (RefSeq) | strong | 31 | 99 |
| | Escherichia coli BL21 | ECD_03984 | | response regulator in two-component regulatory system with BasS | strong | 31 | 100 |
| | Escherichia coli ECOR27 | NOLOHH_04835 | basR | two-component system response regulator BasR | insig. | 31 | 100 |
| | Escherichia coli ECOR38 | HEPCGN_11205 | basR | two-component system response regulator BasR | strong | 31 | 100 |
| | Escherichia coli ECRC101 | MCAODC_03080 | basR | two-component system response regulator BasR | sig. | 31 | 100 |
| | Escherichia coli ECRC102 | NIAGMN_10415 | basR | two-component system response regulator BasR | cofit | 31 | 100 |
| | Escherichia coli ECRC62 | BNILDI_06655 | basR | two-component system response regulator BasR | insig. | 31 | 100 |
| | Escherichia coli ECRC98 | JDDGAC_16205 | basR | two-component system response regulator BasR | insig. | 31 | 100 |
| | Escherichia coli ECRC99 | KEDOAH_15595 | basR | two-component system response regulator BasR | no data | 31 | 100 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03931 | | Transcriptional regulatory protein BasR | insig. | 31 | 100 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4210 | | DNA-binding heavy metal response regulator | insig. | 31 | 99 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3258 | | DNA-binding heavy metal response regulator | insig. | 30 | 99 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS16950 | | transcriptional regulator | insig. | 35 | 99 |
| | Pseudomonas orientalis W4I3 | QF045_RS21660 | | response regulator | insig. | 31 | 100 |
| | Rahnella sp. WP5 | EX31_RS14320 | | envelope stress response regulator transcription factor CpxR | insig. | 34 | 98 |
| | Acinetobacter radioresistens SK82 | MPMX26_03163 | | Transcriptional regulatory protein QseB | cofit | 33 | 98 |
| | Shewanella oneidensis MR-1 | SO4647 | | DNA-binding response regulator (NCBI ptt file) | insig. | 33 | 99 |
| | Pseudomonas sp. SVBP6 | COO64_RS20755 | | response regulator | insig. | 30 | 98 |