| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Shewanella oneidensis MR-1 | SO0860 | | response regulator (NCBI ptt file) | insig. | 100 | 100 |
| o | Shewanella sp. ANA-3 | Shewana3_3418 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 94 | 100 |
| o | Shewanella amazonensis SB2B | Sama_2951 | | response regulator receiver protein (RefSeq) | insig. | 84 | 99 |
| o | Shewanella loihica PV-4 | Shew_3199 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 79 | 99 |
| o | Pseudomonas sp. S08-1 | OH686_00410 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 58 | 99 |
| | Shewanella sp. ANA-3 | Shewana3_0479 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 55 | 100 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_4352 | | Response regulator | insig. | 57 | 99 |
| | Shewanella oneidensis MR-1 | SO4003 | | response regulator (NCBI ptt file) | insig. | 57 | 99 |
| | Shewanella amazonensis SB2B | Sama_3111 | | response regulator receiver protein (RefSeq) | insig. | 57 | 99 |
| | Shewanella sp. ANA-3 | Shewana3_3334 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 56 | 99 |
| o | Alteromonas macleodii MIT1002 | MIT1002_01768 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 55 | 98 |
| | Alteromonas macleodii MIT1002 | MIT1002_00763 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 53 | 98 |
| o | Azospirillum sp. SherDot2 | MPMX19_06045 | | putative cyclic di-GMP phosphodiesterase | insig. | 46 | 99 |
| o | Synechocystis sp000284455 PCC 6803 | SGL_RS09200 | | two-component system response regulator | cofit | 50 | 96 |
| o | Burkholderia phytofirmans PsJN | BPHYT_RS00885 | | chemotaxis protein CheY | insig. | 49 | 99 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS09310 | | two-component system response regulator | insig. | 46 | 99 |
| | Dechlorosoma suillum PS | Dsui_0777 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 46 | 98 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS34710 | | chemotaxis protein CheY | insig. | 45 | 98 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2270 | | Pole remodelling regulatory diguanylate cyclase | insig. | 46 | 94 |
| o | Herbaspirillum seropedicae SmR1 | HSERO_RS06195 | | transcriptional regulator | insig. | 45 | 98 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2310 | | Pole remodelling regulatory diguanylate cyclase | insig. | 44 | 98 |
| o | Desulfovibrio vulgaris Miyazaki F | DvMF_1097 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 45 | 98 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3644 | | Pole remodelling regulatory diguanylate cyclase | insig. | 45 | 98 |
| | Pseudomonas sp. S08-1 | OH686_23605 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 45 | 94 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS20960 | | two-component system response regulator | cofit | 44 | 97 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09305 | | two-component system response regulator | insig. | 43 | 99 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2188.1 | | two-component system regulatory protein | insig. | 43 | 97 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06795 | | two-component system response regulator | insig. | 42 | 95 |
| o | Pseudomonas aeruginosa MRSN321 | DY961_RS09670 | | cyclic di-GMP phosphodiesterase | sig. | 44 | 94 |
| o | Pseudomonas aeruginosa PUPa3 | DQ20_RS52375 | | cyclic di-GMP phosphodiesterase | insig. | 44 | 94 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17390 | | two-component system response regulator | insig. | 43 | 98 |
| | Azospirillum sp. SherDot2 | MPMX19_05749 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 44 | 98 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_29680 | | cyclic di-GMP phosphodiesterase | insig. | 43 | 94 |
| | Dechlorosoma suillum PS | Dsui_1863 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 43 | 98 |
| | Dechlorosoma suillum PS | Dsui_0919 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 43 | 98 |
| o | Pseudomonas sp. RS175 | PFR28_01438 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 42 | 97 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_29820 | | phosphohydrolase | insig. | 41 | 97 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS23460 | | divalent ion tolerance protein CutA | insig. | 41 | 97 |
| | Dechlorosoma suillum PS | Dsui_2782 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | no data | 41 | 94 |
| o | Pseudomonas segetis P6 | ACVTMO_RS19850 | | HD domain-containing phosphohydrolase | insig. | 43 | 94 |
| | Pseudomonas sp. S08-1 | OH686_07455 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 40 | 97 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1771 | | Response regulator | insig. | 44 | 82 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4541 | | Response regulator | insig. | 38 | 94 |
| o | Bosea sp. OAE506 | ABIE41_RS11550 | | HD domain-containing phosphohydrolase | insig. | 38 | 97 |
| o | Rhodopseudomonas palustris CGA009 | TX73_000745 | | response regulator | insig. | 40 | 96 |
| | Pseudomonas stutzeri RCH2 | Psest_2701 | | Response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 42 | 96 |
| o | Desulfovibrio vulgaris Hildenborough JW710 | DVUA0086 | | response regulator (TIGR) | sig. | 38 | 98 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2900.1 | | response regulator | strong | 39 | 93 |
| | Lysobacter sp. OAE881 | ABIE51_RS11560 | | two-component system response regulator | strong | 38 | 93 |
| | Azospirillum sp. SherDot2 | MPMX19_04073 | | hypothetical protein | insig. | 50 | 62 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_15035 | | transcriptional regulator | insig. | 52 | 58 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2545 | | metal dependent phosphohydrolase (RefSeq) | insig. | 49 | 58 |
| | Shewanella amazonensis SB2B | Sama_1789 | | response regulator receiver protein (RefSeq) | insig. | 49 | 59 |
| | Shewanella oneidensis MR-1 | SO2366 | | response regulator (NCBI ptt file) | insig. | 48 | 60 |
| | Shewanella sp. ANA-3 | Shewana3_2105 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 47 | 60 |
| | Shewanella loihica PV-4 | Shew_1983 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 52 | 55 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3602 | | Response regulator | insig. | 48 | 59 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2418 | | Response regulator | insig. | 47 | 56 |
| | Azospirillum sp. SherDot2 | MPMX19_05513 | | 3'3'-cGAMP-specific phosphodiesterase 2 | insig. | 45 | 55 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0722 | | response regulator (TIGR) | insig. | 45 | 57 |
| | Methylophilus sp. DMC18 | GFF1506 | | hypothetical protein | insig. | 49 | 51 |
| | Shewanella loihica PV-4 | Shew_1882 | | metal dependent phosphohydrolase (RefSeq) | insig. | 45 | 55 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06540 | | metal-dependent phosphohydrolase | insig. | 44 | 58 |
| | Azospirillum brasilense Sp245 | AZOBR_RS26775 | | hisitidine kinase | sig. | 46 | 53 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS12565 | | HD domain-containing protein | insig. | 44 | 54 |
| | Dechlorosoma suillum PS | Dsui_2629 | | HD-GYP domain-containing protein | cofit | 44 | 62 |
| | Dechlorosoma suillum PS | Dsui_1836 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 42 | 56 |
| | Dechlorosoma suillum PS | Dsui_1228 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 43 | 61 |
| | Azospirillum sp. SherDot2 | MPMX19_05263 | | hypothetical protein | insig. | 44 | 55 |
| | Shewanella oneidensis MR-1 | SO1387 | | HD domain protein (NCBI ptt file) | insig. | 43 | 55 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1407 | | metal dependent phosphohydrolase (RefSeq) | insig. | 39 | 69 |
| | Alteromonas macleodii MIT1002 | MIT1002_02465 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 42 | 56 |
| | Alteromonas macleodii MIT1002 | MIT1002_01516 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 43 | 59 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1181 | | response regulator (TIGR) | cofit | 35 | 92 |
| | Rhodospirillum rubrum S1H | Rru_A3180 | | Metal dependent phosphohydrolase, HD region (NCBI) | insig. | 41 | 53 |
| | Shewanella loihica PV-4 | Shew_2713 | | metal dependent phosphohydrolase (RefSeq) | insig. | 44 | 53 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS21195 | | phosphohydrolase | insig. | 41 | 50 |
| | Dechlorosoma suillum PS | Dsui_3001 | | putative domain HDIG-containing protein | insig. | 32 | 88 |
| | Azospirillum sp. SherDot2 | MPMX19_01880 | | hypothetical protein | insig. | 40 | 64 |
| | Azospirillum brasilense Sp245 | AZOBR_RS03050 | | diguanylate cyclase | sig. | 55 | 38 |
| | Azospirillum sp. SherDot2 | MPMX19_02025 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 54 | 38 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_3074 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | cofit | 31 | 95 |
| | Dechlorosoma suillum PS | Dsui_3000 | | putative domain HDIG-containing protein | insig. | 32 | 92 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS16755 | | HD-GYP domain-containing protein | insig. | 45 | 50 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS06150 | | HD-GYP domain-containing protein | cofit | 39 | 57 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09195 | | hybrid sensor histidine kinase/response regulator | insig. | 54 | 38 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS02865 | | response regulator | insig. | 30 | 95 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS08635 | | response regulator | sig. | 47 | 53 |
| | Dechlorosoma suillum PS | Dsui_3287 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 51 | 39 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS11770 | | HD domain-containing protein | insig. | 41 | 55 |
| | Enterobacter sp. TBS_079 | MPMX20_02814 | | hypothetical protein | insig. | 40 | 52 |
| | Shewanella amazonensis SB2B | Sama_3396 | | response regulator receiver protein (RefSeq) | insig. | 46 | 45 |
| | Azospirillum brasilense Sp245 | AZOBR_RS22690 | | sensor protein | insig. | 50 | 43 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_05340 | | HD-GYP domain-containing protein | insig. | 41 | 48 |
| | Sphingobium sp. HT1-2 | GFF2748 | | Pole remodelling regulatory diguanylate cyclase | cofit | 47 | 39 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3168 | | Response regulator | insig. | 29 | 96 |
| | Dechlorosoma suillum PS | Dsui_3334 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 42 | 50 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1513 | | metal dependent phosphohydrolase (RefSeq) | insig. | 40 | 54 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_07645 | | Phosphohydrolase | insig. | 36 | 59 |
| | Azospirillum sp. SherDot2 | MPMX19_02416 | | 3'3'-cGAMP-specific phosphodiesterase 2 | insig. | 35 | 55 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS31465 | | diguanylate cyclase | insig. | 48 | 38 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS08055 | | two-component system response regulator | cofit | 31 | 83 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS17470 | | HD domain-containing phosphohydrolase | insig. | 36 | 59 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS17245 | | HD domain-containing protein | insig. | 36 | 59 |
| | Azospirillum brasilense Sp245 | AZOBR_RS00185 | | transcriptional regulator | insig. | 33 | 59 |
| | Azospirillum brasilense Sp245 | AZOBR_RS22685 | | response regulator PleD (with diguanylate cyclase and response regulator receiver domains) (fragment) | insig. | 58 | 33 |
| | Shewanella loihica PV-4 | Shew_0981 | | response regulator receiver protein (RefSeq) | insig. | 48 | 39 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03106 | | PAS domain S-box-containing protein | insig. | 44 | 42 |
| | Rhizobium sp. OAE497 | ABIE40_RS05520 | | HD-GYP domain-containing protein | insig. | 38 | 53 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3123 | | HD domain protein (TIGR) | insig. | 34 | 58 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_18790 | | metal-dependent phosphohydrolase | insig. | 36 | 53 |
| | Pseudomonas sp. S08-1 | OH686_23615 | | Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY | insig. | 44 | 42 |
| | Azospirillum sp. SherDot2 | MPMX19_01522 | | Response regulator PleD | insig. | 43 | 44 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS18655 | | response regulator | insig. | 50 | 35 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1460 | | putative PAS/PAC sensor protein (RefSeq) | cofit | 35 | 60 |
| | Paraburkholderia graminis OAS925 | ABIE53_004192 | | PAS domain S-box-containing protein | strong | 43 | 42 |
| | Shewanella sp. ANA-3 | Shewana3_0481 | | response regulator receiver protein (RefSeq) | cofit | 44 | 42 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS23555 | | HD domain-containing protein | insig. | 36 | 59 |
| | Shewanella loihica PV-4 | Shew_3790 | | response regulator receiver modulated diguanylate cyclase (RefSeq) | insig. | 50 | 36 |
| | Shewanella amazonensis SB2B | Sama_0065 | | response regulator receiver protein (RefSeq) | insig. | 41 | 52 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0129 | | sensory box/HDIG domain protein (TIGR) | insig. | 34 | 60 |
| | Caulobacter crescentus NA1000 | CCNA_02546 | | GGDEF/response regulator protein PleD | strong | 50 | 34 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02546 | | GGDEF/response regulator protein PleD | cofit | 50 | 34 |
| | Dechlorosoma suillum PS | Dsui_3468 | | Response regulator receiver domain protein,histidine kinase | cofit | 46 | 41 |
| | Azospirillum sp. SherDot2 | MPMX19_00086 | | 3'3'-cGAMP-specific phosphodiesterase 2 | insig. | 39 | 43 |
| | Shewanella sp. ANA-3 | Shewana3_2820 | | metal dependent phosphohydrolase (RefSeq) | insig. | 36 | 57 |
| | Shewanella sp. ANA-3 | Shewana3_4015 | | response regulator receiver modulated diguanylate cyclase (RefSeq) | cofit | 42 | 46 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2271 | | Response regulator | insig. | 41 | 45 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS04990 | | HD-GYP domain-containing protein | insig. | 41 | 48 |
| | Ralstonia solanacearum UW163 | UW163_RS08635 | | HD-GYP domain-containing protein | insig. | 41 | 48 |
| | Marinobacter adhaerens HP15 | HP15_1054 | | multi-sensor signal transduction histidine kinase | strong | 39 | 47 |
| | Pseudomonas segetis P6 | ACVTMO_RS02300 | | response regulator | insig. | 48 | 35 |
| | Azospirillum brasilense Sp245 | AZOBR_RS16180 | | diguanylate cyclase | strong | 44 | 44 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS30905 | | histidine kinase | insig. | 40 | 42 |
| | Methylophilus sp. DMC18 | GFF1903 | | hypothetical protein | insig. | 37 | 51 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_181 | | Two-component response regulator | insig. | 48 | 34 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS12300 | | HD-GYP domain-containing protein | insig. | 40 | 48 |
| | Marinobacter adhaerens HP15 | HP15_3421 | | metal-dependent phosphohydrolase, HD subdomain protein | insig. | 39 | 52 |
| | Rhizobium sp. OAE497 | ABIE40_RS28400 | | HD-GYP domain-containing protein | insig. | 38 | 48 |
| | Pseudomonas sp. S08-1 | OH686_16560 | | Two-component transcriptional response regulator, LuxR family | insig. | 48 | 34 |
| | Shewanella loihica PV-4 | Shew_3670 | | metal dependent phosphohydrolase (RefSeq) | insig. | 46 | 37 |
| | Pseudomonas simiae WCS417 | PS417_11585 | | LuxR family transcriptional regulator | insig. | 48 | 34 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS20605 | | response regulator | insig. | 46 | 39 |
| | Ralstonia solanacearum GMI1000 | RS_RS12610 | | HD-GYP domain-containing protein | insig. | 40 | 48 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS12370 | | response regulator transcription factor | insig. | 48 | 34 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS12370 | | response regulator transcription factor | insig. | 48 | 34 |
| | Azospirillum sp. SherDot2 | MPMX19_04589 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 48 | 34 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS06810 | | response regulator | insig. | 46 | 39 |
| | Azospirillum sp. SherDot2 | MPMX19_04108 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 48 | 36 |
| | Pantoea sp. MT58 | IAI47_01225 | | HD-GYP domain-containing protein | insig. | 39 | 48 |
| | Shewanella sp. ANA-3 | Shewana3_4069 | | metal dependent phosphohydrolase (RefSeq) | strong | 46 | 37 |
| | Agrobacterium fabrum C58 | Atu2291 | | hypothetical protein | insig. | 38 | 48 |
| | Shewanella amazonensis SB2B | Sama_0748 | | response regulator receiver protein (RefSeq) | sig. | 43 | 37 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS13405 | | phosphodiesterase | insig. | 34 | 63 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS32075 | | response regulator | insig. | 43 | 44 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0491 | | HDIG domain protein (TIGR) | insig. | 37 | 49 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS20710 | | HD-GYP domain-containing protein | cofit | 38 | 48 |
| | Marinobacter adhaerens HP15 | HP15_3532 | | Metal-dependent phosphohydrolase, HD subdomain protein | insig. | 36 | 50 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS14075 | | HD-GYP domain-containing protein | insig. | 37 | 51 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_2939 | | response regulator receiver modulated diguanylate cyclase | no data | 48 | 37 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2939 | | response regulator receiver modulated diguanylate cyclase | no data | 48 | 37 |
| | Bosea sp. OAE506 | ABIE41_RS18170 | | PleD family two-component system response regulator | insig. | 40 | 48 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS01775 | | HD-GYP domain-containing protein | insig. | 36 | 52 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_0994 | | Metal-dependent phosphohydrolase, HD subdomain protein | insig. | 36 | 51 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0994 | | Metal-dependent phosphohydrolase, HD subdomain protein | insig. | 36 | 51 |
| | Rhizobium sp. OAE497 | ABIE40_RS07330 | | PleD family two-component system response regulator | cofit | 35 | 61 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c16320 | | putative metal dependent phosphohydrolase | insig. | 32 | 47 |
| | Shewanella oneidensis MR-1 | SO4711 | | HD domain protein (NCBI ptt file) | strong | 44 | 37 |
| | Agrobacterium fabrum C58 | Atu1297 | | two component response regulator | insig. | 40 | 45 |
| | Pseudomonas stutzeri RCH2 | Psest_2721 | | HD-GYP domain | insig. | 39 | 48 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03320 | | EAL domain-containing protein | insig. | 39 | 41 |
| | Rhizobium sp. OAE497 | ABIE40_RS13525 | | HD-GYP domain-containing protein | insig. | 37 | 50 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS22750 | | response regulator transcription factor | insig. | 40 | 51 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS28015 | | cyclic di-GMP phosphodiesterase | insig. | 37 | 48 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS47620 | | cyclic di-GMP phosphodiesterase | insig. | 37 | 48 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS26120 | | HD domain-containing protein | insig. | 36 | 48 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS26120 | | HD domain-containing protein | insig. | 36 | 48 |
| | Shewanella amazonensis SB2B | Sama_3594 | | response regulator receiver protein (RefSeq) | insig. | 42 | 41 |
| | Sinorhizobium meliloti 1021 | SMc01370 | | response regulator PleD | insig. | 45 | 39 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3695 | | Two-component response regulator | sig. | 37 | 57 |
| | Variovorax sp. SCN45 | GFF638 | | Two-component transcriptional response regulator, LuxR family | insig. | 44 | 35 |
| | Shewanella amazonensis SB2B | Sama_0136 | | putative metal dependent phosphohydrolase (RefSeq) | cofit | 43 | 37 |
| | Pseudomonas segetis P6 | ACVTMO_RS00915 | | HD-GYP domain-containing protein | insig. | 41 | 48 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03035 | | diguanylate cyclase | sig. | 39 | 42 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS04880 | | phosphodiesterase | insig. | 38 | 53 |
| | Pseudomonas stutzeri RCH2 | Psest_4130 | | uncharacterized domain HDIG | insig. | 34 | 59 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2933 | | response regulator/sensory box/HDIG domain protein (TIGR) | strong | 31 | 60 |
| | Rhodopseudomonas palustris CGA009 | TX73_006410 | | response regulator transcription factor | insig. | 46 | 34 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_895 | | HDIG domain protein | insig. | 37 | 47 |
| | Paraburkholderia graminis OAS925 | ABIE53_004362 | | DNA-binding response OmpR family regulator | insig. | 42 | 39 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS00610 | | HD-GYP domain-containing protein | insig. | 39 | 48 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS13200 | | transcriptional regulator | insig. | 43 | 35 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3270 | | Two-component response regulator | insig. | 41 | 41 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1338 | | metal dependent phosphohydrolase (RefSeq) | insig. | 39 | 44 |
| | Azospirillum brasilense Sp245 | AZOBR_RS00880 | | regulator | sig. | 37 | 41 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0128 | | uncharacterized domain HDIG | insig. | 34 | 49 |
| | Dechlorosoma suillum PS | Dsui_0643 | | HD-GYP domain-containing protein | insig. | 32 | 64 |
| | Pseudomonas segetis P6 | ACVTMO_RS10595 | | HD-GYP domain-containing protein | insig. | 35 | 51 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS25540 | | phosphohydrolase | insig. | 34 | 49 |
| | Marinobacter adhaerens HP15 | HP15_4053 | | metal-dependent phosphohydrolase, HD subdomain protein | insig. | 32 | 50 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_780 | | HDIG domain protein | insig. | 33 | 64 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS19965 | | phosphodiesterase | insig. | 36 | 50 |
| | Shewanella sp. ANA-3 | Shewana3_1079 | | metal dependent phosphohydrolase (RefSeq) | insig. | 35 | 52 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS23505 | | transcriptional regulator | strong | 32 | 51 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0130 | | uncharacterized domain HDIG | insig. | 31 | 50 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01996 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | strong | 37 | 42 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21160 | | cyclic di-GMP phosphodiesterase | insig. | 35 | 48 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0129 | | uncharacterized domain HDIG | insig. | 33 | 50 |
| | Marinobacter adhaerens HP15 | HP15_4049 | | HD-GYP domain protein | insig. | 39 | 47 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1148 | | metal dependent phosphohydrolase | insig. | 30 | 68 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3334 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | strong | 37 | 42 |
| | Rhodopseudomonas palustris CGA009 | TX73_016195 | | PleD family two-component system response regulator | insig. | 48 | 34 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04496 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | strong | 44 | 37 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0972 | | HD domain protein (TIGR) | insig. | 38 | 43 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.460.1 | | HDIG domain protein | insig. | 37 | 48 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS03355 | | two-component system response regulator | insig. | 35 | 49 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS09900 | | two-component regulator propeller domain-containing protein | insig. | 39 | 38 |
| | Variovorax sp. SCN45 | GFF2488 | | Two-component transcriptional response regulator, LuxR family | insig. | 39 | 40 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04986 | | Cyclic di-GMP phosphodiesterase | cofit | 34 | 48 |
| | Methylophilus sp. DMC18 | GFF1954 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | cofit | 46 | 34 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS02130 | | hybrid sensor histidine kinase/response regulator | strong | 41 | 42 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS23735 | | phosphodiesterase | insig. | 36 | 48 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS04305 | | HD domain-containing protein | cofit | 35 | 49 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS18645 | | chemotaxis protein CheY | insig. | 25 | 95 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS03625 | | response regulator | insig. | 44 | 35 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_03275 | | hybrid sensor histidine kinase/response regulator | insig. | 42 | 34 |
| | Dechlorosoma suillum PS | Dsui_0938 | | HD-GYP domain-containing protein | insig. | 32 | 60 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1754 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | strong | 37 | 48 |
| | Variovorax sp. OAS795 | ABID97_RS23505 | | response regulator transcription factor | insig. | 37 | 42 |
| | Pseudomonas sp. S08-1 | OH686_14780 | | HD-GYP domain | insig. | 37 | 48 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS04735 | | phosphodiesterase | insig. | 33 | 63 |
| | Dechlorosoma suillum PS | Dsui_1886 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 28 | 94 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS11870 | | AraC family transcriptional regulator | insig. | 39 | 39 |
| | Shewanella oneidensis MR-1 | SO3491 | | HDIG domain protein (NCBI ptt file) | insig. | 34 | 47 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS11205 | | hybrid sensor histidine kinase/response regulator | insig. | 42 | 38 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04086 | | response regulator receiver domain protein | insig. | 40 | 41 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS11200 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 40 | 38 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1098 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) | insig. | 36 | 50 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1098 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) | insig. | 36 | 50 |
| | Azospirillum sp. SherDot2 | MPMX19_01958 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 37 | 50 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS15245 | | response regulator | insig. | 41 | 38 |
| | Variovorax sp. SCN45 | GFF5870 | | hypothetical protein | cofit | 40 | 42 |
| | Dechlorosoma suillum PS | Dsui_0757 | | HD-GYP domain-containing protein | insig. | 38 | 48 |
| | Cellulophaga baltica 18 | M666_RS00005 | | two-component regulator propeller domain-containing protein | insig. | 42 | 38 |
| | Rhizobium sp. OAE497 | ABIE40_RS14675 | | response regulator transcription factor | insig. | 41 | 34 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03092 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | cofit | 39 | 48 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14285 | | transcriptional regulator | strong | 38 | 45 |
| | Alteromonas macleodii MIT1002 | MIT1002_04107 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 38 | 43 |
| | Marinobacter adhaerens HP15 | HP15_p187g147 | | HD-GYP domain protein | insig. | 35 | 48 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS05625 | | two-component system response regulator | insig. | 28 | 91 |