Conservation of cofitness between SMc00960 and SMc00897 in Sinorhizobium meliloti 1021

86 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc00960 hypothetical protein 1.0 SMc00897 PMBA protein 0.49 1
Rhizobium sp. OAE497 0.88 ABIE40_RS04050 metalloprotease TldD 0.70 ABIE40_RS03780 TldD/PmbA family protein 0.95 3
Agrobacterium fabrum C58 0.88 Atu0765 TldD 0.73 Atu0693 PmbA/TldD related protein 0.28 5
Rhodopseudomonas palustris CGA009 0.69 TX73_004255 metalloprotease TldD 0.50 TX73_005930 TldD/PmbA family protein 0.71 1
Azospirillum sp. SherDot2 0.62 MPMX19_00882 Metalloprotease TldD 0.47 MPMX19_01886 Metalloprotease PmbA 0.54 16
Azospirillum brasilense Sp245 0.62 AZOBR_RS10600 peptidase C69 0.49 AZOBR_RS11930 modulator protein 0.79 1
Rhodospirillum rubrum S1H 0.61 Rru_A0567 Peptidase U62, modulator of DNA gyrase (NCBI) 0.42 Rru_A0575 Peptidase U62, modulator of DNA gyrase (NCBI) 0.64 1
Magnetospirillum magneticum AMB-1 0.61 AMB_RS21030 metalloprotease TldD 0.44 AMB_RS22120 TldD/PmbA family protein low > 64
Caulobacter crescentus NA1000 Δfur 0.60 CCNA_03522 Zn-dependent protease TldD 0.36 CCNA_00311 Zn-dependent protease family protein low > 67
Phaeobacter inhibens DSM 17395 0.60 PGA1_c06240 protein TldD 0.41 PGA1_c33480 protein PmbA — —
Caulobacter crescentus NA1000 0.60 CCNA_03522 Zn-dependent protease TldD 0.36 CCNA_00311 Zn-dependent protease family protein 0.92 1
Dinoroseobacter shibae DFL-12 0.59 Dshi_1139 peptidase U62 modulator of DNA gyrase (RefSeq) 0.35 Dshi_0064 peptidase U62 modulator of DNA gyrase (RefSeq) low > 64
Sphingomonas koreensis DSMZ 15582 0.58 Ga0059261_2252 Predicted Zn-dependent proteases and their inactivated homologs 0.43 Ga0059261_0810 Predicted Zn-dependent proteases and their inactivated homologs low > 68
Brevundimonas sp. GW460-12-10-14-LB2 0.57 A4249_RS10860 metalloprotease TldD 0.34 A4249_RS09195 TldD/PmbA family protein low > 48
Alteromonas macleodii MIT1002 0.52 MIT1002_00227 protease TldD 0.28 MIT1002_00230 peptidase PmbA 0.80 1
Pseudomonas putida KT2440 0.52 PP_0940 putative protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD 0.28 PP_0942 regulatory protease 0.57 1
Lysobacter sp. OAE881 0.51 ABIE51_RS06795 metalloprotease TldD 0.26 ABIE51_RS06805 metalloprotease PmbA 0.62 39
Hydrogenophaga sp. GW460-11-11-14-LB1 0.51 GFF580 TldD protein, part of TldE/TldD proteolytic complex 0.29 GFF3655 TldE protein, part of TldE/TldD proteolytic complex 0.93 1
Variovorax sp. OAS795 0.51 ABID97_RS06335 metalloprotease TldD 0.30 ABID97_RS20695 metalloprotease PmbA 0.93 1
Variovorax sp. SCN45 0.51 GFF4449 TldD protein, part of TldE/TldD proteolytic complex 0.31 GFF4697 TldE protein, part of TldE/TldD proteolytic complex 0.83 104
Ralstonia sp. UNC404CL21Col 0.51 ABZR87_RS01105 metalloprotease TldD 0.29 ABZR87_RS09660 metalloprotease PmbA 0.78 1
Acidovorax sp. GW101-3H11 0.51 Ac3H11_4036 TldD protein, part of TldE/TldD proteolytic complex 0.28 Ac3H11_3262 TldE protein, part of TldE/TldD proteolytic complex 0.36 33
Xanthomonas campestris pv. campestris strain 8004 0.51 Xcc-8004.1883.1 TldD protein, part of TldE/TldD proteolytic complex 0.30 Xcc-8004.1885.1 TldE protein, part of TldE/TldD proteolytic complex 0.76 1
Ralstonia solanacearum PSI07 0.51 RPSI07_RS11850 metalloprotease TldD 0.28 RPSI07_RS19505 metalloprotease PmbA low > 81
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.27 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.36 10
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.27 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.38 9
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS21715 metalloprotease TldD 0.34 ABZR86_RS21700 metalloprotease PmbA 0.53 6
Ralstonia solanacearum GMI1000 0.51 RS_RS13315 metalloprotease TldD 0.26 RS_RS04700 metalloprotease PmbA 0.58 18
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_05215 protease TldD 0.27 AO353_05205 peptidase PmbA 0.83 1
Cupriavidus basilensis FW507-4G11 0.50 RR42_RS05875 protease TldD 0.28 RR42_RS14750 peptidase PMbA 0.67 1
Dechlorosoma suillum PS 0.50 Dsui_3401 putative Zn-dependent protease-like protein 0.30 Dsui_1234 putative Zn-dependent protease-like protein 0.84 3
Ralstonia solanacearum IBSBF1503 0.50 RALBFv3_RS05455 metalloprotease TldD 0.28 RALBFv3_RS13965 metalloprotease PmbA 0.80 4
Ralstonia solanacearum UW163 0.50 UW163_RS08170 metalloprotease TldD 0.28 UW163_RS15845 metalloprotease PmbA — —
Pseudomonas fluorescens SBW25 0.50 PFLU_RS04340 metalloprotease TldD 0.28 PFLU_RS04350 metalloprotease PmbA 0.48 48
Pseudomonas fluorescens SBW25-INTG 0.50 PFLU_RS04340 metalloprotease TldD 0.28 PFLU_RS04350 metalloprotease PmbA 0.69 1
Pseudomonas simiae WCS417 0.50 PS417_04285 protease TldD 0.28 PS417_04295 peptidase PmbA 0.64 1
Pseudomonas fluorescens FW300-N2E2 0.50 Pf6N2E2_3280 TldD protein, part of TldE/TldD proteolytic complex 0.28 Pf6N2E2_3278 TldE protein, part of TldE/TldD proteolytic complex 0.71 1
Pseudomonas fluorescens GW456-L13 0.50 PfGW456L13_5026 TldD protein, part of TldE/TldD proteolytic complex 0.27 PfGW456L13_5024 TldE protein, part of TldE/TldD proteolytic complex low > 87
Pseudomonas fluorescens FW300-N1B4 0.50 Pf1N1B4_1092 TldD protein, part of TldE/TldD proteolytic complex 0.27 Pf1N1B4_1090 TldE protein, part of TldE/TldD proteolytic complex 0.39 2
Pantoea sp. MT58 0.50 IAI47_02465 metalloprotease TldD 0.30 IAI47_02765 metalloprotease PmbA 0.93 1
Pseudomonas fluorescens FW300-N2C3 0.50 AO356_07095 protease TldD 0.27 AO356_07085 peptidase PmbA 0.75 1
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_02220 metalloprotease TldD 0.29 CSW01_12845 metalloprotease PmbA 0.89 4
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_10280 tldD metalloprotease TldD 0.32 OKGIIK_10260 pmbA metalloprotease PmbA 0.68 10
Rhodanobacter denitrificans MT42 0.49 LRK55_RS03145 metalloprotease TldD 0.32 LRK55_RS03125 metalloprotease PmbA 0.69 42
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS03395 metalloprotease TldD 0.32 LRK54_RS03375 metalloprotease PmbA 0.96 1
Kangiella aquimarina DSM 16071 0.49 B158DRAFT_2072 microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.27 B158DRAFT_2075 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.48 1
Pseudomonas stutzeri RCH2 0.49 Psest_3320 Predicted Zn-dependent proteases and their inactivated homologs 0.27 Psest_3318 Predicted Zn-dependent proteases and their inactivated homologs 0.46 1
Dickeya dadantii 3937 0.49 DDA3937_RS01460 metalloprotease TldD 0.29 DDA3937_RS01500 metalloprotease PmbA 0.91 1
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS03540 peptidase C69 0.27 BPHYT_RS14705 peptidase C69 0.27 34
Pseudomonas sp. RS175 0.49 PFR28_00161 Metalloprotease TldD 0.28 PFR28_00163 Metalloprotease PmbA 0.68 1
Castellaniella sp019104865 MT123 0.49 ABCV34_RS02590 metalloprotease TldD 0.28 ABCV34_RS10610 metalloprotease PmbA low > 48
Paraburkholderia sabiae LMG 24235 0.49 QEN71_RS26555 metalloprotease TldD 0.27 QEN71_RS04270 metalloprotease PmbA 0.87 30
Herbaspirillum seropedicae SmR1 0.49 HSERO_RS07155 peptidase C69 0.30 HSERO_RS09265 peptidase C69 0.46 1
Dickeya dianthicola 67-19 0.49 HGI48_RS01380 metalloprotease TldD 0.29 HGI48_RS01415 metalloprotease PmbA low > 71
Escherichia coli ECOR27 0.48 NOLOHH_09555 tldD metalloprotease TldD 0.30 NOLOHH_04185 pmbA metalloprotease PmbA low > 57
Escherichia coli BL21 0.48 ECD_03104 putative peptidase 0.30 ECD_04103 putative antibiotic peptide MccB17 maturation peptidase 0.68 2
Escherichia coli ECRC62 0.48 BNILDI_01980 tldD metalloprotease TldD 0.30 BNILDI_07325 pmbA metalloprotease PmbA — —
Serratia liquefaciens MT49 0.48 IAI46_22685 metalloprotease TldD 0.30 IAI46_22575 metalloprotease PmbA 0.55 15
Escherichia fergusonii Becca 0.48 EFB2_00586 Metalloprotease TldD 0.31 EFB2_04298 Metalloprotease PmbA low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.48 OHPLBJKB_00460 Metalloprotease TldD 0.30 OHPLBJKB_03800 Metalloprotease PmbA low > 73
Escherichia coli Nissle 1917 0.48 ECOLIN_RS18595 metalloprotease TldD 0.31 ECOLIN_RS24570 metalloprotease PmbA low > 52
Escherichia coli ECOR38 0.48 HEPCGN_16620 tldD metalloprotease TldD 0.30 HEPCGN_10125 pmbA metalloprotease PmbA low > 85
Escherichia coli BW25113 0.48 b3244 tldD predicted peptidase (NCBI) 0.30 b4235 pmbA predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) 0.75 1
Escherichia coli ECRC101 0.48 MCAODC_08275 tldD metalloprotease TldD 0.30 MCAODC_02430 pmbA metalloprotease PmbA — —
Dickeya dianthicola ME23 0.48 DZA65_RS01440 metalloprotease TldD 0.29 DZA65_RS01480 metalloprotease PmbA low > 75
Escherichia coli ECRC99 0.48 KEDOAH_10395 tldD metalloprotease TldD 0.30 KEDOAH_16230 pmbA metalloprotease PmbA — —
Escherichia coli ECRC98 0.48 JDDGAC_21380 tldD metalloprotease TldD 0.30 JDDGAC_15565 pmbA metalloprotease PmbA — —
Escherichia coli ECRC101 0.48 OKFHMN_17755 tldD metalloprotease TldD 0.30 OKFHMN_11925 pmbA metalloprotease PmbA — —
Escherichia coli ECRC102 0.48 NIAGMN_15515 tldD metalloprotease TldD 0.30 NIAGMN_09775 pmbA metalloprotease PmbA — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.48 GFF2140 TldD protein, part of TldE/TldD proteolytic complex 0.30 GFF904 TldE protein, part of TldE/TldD proteolytic complex 0.53 7
Shewanella sp. ANA-3 0.48 Shewana3_3641 microcin-processing peptidase 2 (RefSeq) 0.28 Shewana3_3631 microcin-processing peptidase 1 (RefSeq) 0.56 2
Pseudomonas sp. S08-1 0.48 OH686_08580 TldD protein, part of TldE/TldD proteolytic complex 0.26 OH686_08570 TldE protein, part of TldE/TldD proteolytic complex 0.63 61
Enterobacter sp. TBS_079 0.48 MPMX20_04151 Metalloprotease TldD 0.30 MPMX20_00517 Metalloprotease PmbA 0.31 13
Klebsiella michiganensis M5al 0.48 BWI76_RS25470 metalloprotease TldD 0.30 BWI76_RS02850 metalloprotease PmbA low > 92
Paraburkholderia bryophila 376MFSha3.1 0.48 H281DRAFT_04688 microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.27 H281DRAFT_04304 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.51 1
Paraburkholderia graminis OAS925 0.48 ABIE53_000851 TldD protein 0.27 ABIE53_003116 PmbA protein 0.68 1
Pectobacterium carotovorum WPP14 0.48 HER17_RS20140 metalloprotease TldD 0.30 HER17_RS20090 metalloprotease PmbA low > 75
Erwinia tracheiphila SCR3 0.47 LU632_RS21420 tldD metalloprotease TldD 0.28 LU632_RS02145 pmbA metalloprotease PmbA 0.75 25
Enterobacter asburiae PDN3 0.47 EX28DRAFT_3295 Predicted Zn-dependent proteases and their inactivated homologs 0.31 EX28DRAFT_3422 Predicted Zn-dependent proteases and their inactivated homologs low > 76
Shewanella loihica PV-4 0.47 Shew_0410 peptidase U62, modulator of DNA gyrase (RefSeq) 0.27 Shew_0416 peptidase U62, modulator of DNA gyrase (RefSeq) 0.65 3
Rahnella sp. WP5 0.47 EX31_RS12265 metalloprotease TldD 0.30 EX31_RS12320 metalloprotease PmbA 0.30 78
Shewanella amazonensis SB2B 0.46 Sama_0474 TldD protein (RefSeq) 0.28 Sama_0482 PmbA protein (RefSeq) 0.89 1
Shewanella oneidensis MR-1 0.46 SO4091 tldD tldD protein (NCBI ptt file) 0.28 SO4078 pmbA pmba protein (NCBI ptt file) 0.65 1
Bacteroides thetaiotaomicron VPI-5482 0.33 BT3648 putative modulator of DNA gyrase (NCBI ptt file) 0.19 BT3649 putative modulator of DNA gyrase (NCBI ptt file) 0.22 10
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS03620 TldD/PmbA family protein 0.17 HMPREF1078_RS03625 TldD/PmbA family protein 0.84 1
Bacteroides stercoris CC31F 0.31 HMPREF1181_RS03165 TldD/PmbA family protein 0.18 HMPREF1181_RS03170 TldD/PmbA family protein low > 56
Synechococcus elongatus PCC 7942 0.21 Synpcc7942_1127 tldD microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.09 Synpcc7942_1589 pmbA putative modulator of DNA gyrase low > 38

Not shown: 1 genomes with orthologs for SMc00960 only; 3 genomes with orthologs for SMc00897 only