Conservation of cofitness between QEN71_RS03060 and QEN71_RS03065 in Paraburkholderia sabiae LMG 24235

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Paraburkholderia sabiae LMG 24235 1.0 QEN71_RS03060 quinolinate synthase NadA 1.0 QEN71_RS03065 carboxylating nicotinate-nucleotide diphosphorylase 0.97 1
Burkholderia phytofirmans PsJN 0.91 BPHYT_RS15650 quinolinate synthetase 0.80 BPHYT_RS15645 nicotinate-nucleotide pyrophosphorylase 0.94 2
Paraburkholderia graminis OAS925 0.90 ABIE53_003294 quinolinate synthase 0.78 ABIE53_003293 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.88 2
Paraburkholderia bryophila 376MFSha3.1 0.90 H281DRAFT_04071 quinolinate synthetase 0.74 H281DRAFT_04070 nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.91 2
Ralstonia sp. UNC404CL21Col 0.76 ABZR87_RS00355 quinolinate synthase NadA 0.67 ABZR87_RS00350 carboxylating nicotinate-nucleotide diphosphorylase 0.95 1
Herbaspirillum seropedicae SmR1 0.76 HSERO_RS11065 quinolinate synthetase 0.63 HSERO_RS11070 nicotinate-nucleotide pyrophosphorylase 0.87 1
Cupriavidus basilensis FW507-4G11 0.75 RR42_RS17020 quinolinate synthetase 0.66 RR42_RS17015 nicotinate-nucleotide pyrophosphorylase low > 128
Ralstonia solanacearum GMI1000 0.75 RS_RS12295 quinolinate synthase 0.63 RS_RS12290 nicotinate-nucleotide diphosphorylase (carboxylating) 0.84 1
Ralstonia solanacearum PSI07 0.75 RPSI07_RS12650 quinolinate synthase NadA 0.66 RPSI07_RS12655 nicotinate-nucleotide diphosphorylase (carboxylating) low > 81
Ralstonia solanacearum IBSBF1503 0.75 RALBFv3_RS04735 quinolinate synthase NadA 0.65 RALBFv3_RS04730 nicotinate-nucleotide diphosphorylase (carboxylating) low > 76
Ralstonia solanacearum UW163 0.75 UW163_RS08935 quinolinate synthase NadA 0.65 UW163_RS08940 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Castellaniella sp019104865 MT123 0.70 ABCV34_RS03700 quinolinate synthase NadA 0.59 ABCV34_RS03695 carboxylating nicotinate-nucleotide diphosphorylase low > 48
Variovorax sp. OAS795 0.66 ABID97_RS07415 quinolinate synthase NadA 0.47 ABID97_RS07410 carboxylating nicotinate-nucleotide diphosphorylase 0.97 1
Acidovorax sp. GW101-3H11 0.66 Ac3H11_3837 Quinolinate synthetase (EC 2.5.1.72) 0.52 Ac3H11_3838 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.97 1
Variovorax sp. SCN45 0.65 GFF2575 Quinolinate synthetase (EC 2.5.1.72) 0.45 GFF2574 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.91 1
Hydrogenophaga sp. GW460-11-11-14-LB1 0.65 GFF1216 Quinolinate synthetase (EC 2.5.1.72) 0.52 GFF1217 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 90
Marinobacter adhaerens HP15 0.61 HP15_2032 quinolinate synthetase complex, A subunit 0.47 HP15_1305 nicotinate-nucleotide pyrophosphorylase — —
Shewanella amazonensis SB2B 0.61 Sama_1712 quinolinate synthetase (RefSeq) 0.44 Sama_0371 nicotinate-nucleotide diphosphorylase (carboxylating) (RefSeq) — —
Shewanella loihica PV-4 0.60 Shew_1928 quinolinate synthetase (RefSeq) 0.41 Shew_3435 nicotinate-nucleotide pyrophosphorylase (RefSeq) — —
Shewanella sp. ANA-3 0.59 Shewana3_2128 quinolinate synthetase (RefSeq) 0.40 Shewana3_0422 nicotinate-nucleotide pyrophosphorylase [carboxylating] (RefSeq) — —
Pseudomonas stutzeri RCH2 0.59 Psest_1509 quinolinate synthetase complex, A subunit 0.50 Psest_0718 nicotinate-nucleotide pyrophosphorylase 0.77 1
Pectobacterium carotovorum WPP14 0.59 HER17_RS14820 quinolinate synthase NadA 0.45 HER17_RS03250 carboxylating nicotinate-nucleotide diphosphorylase 0.96 4
Serratia liquefaciens MT49 0.58 IAI46_06380 quinolinate synthase NadA 0.42 IAI46_03530 carboxylating nicotinate-nucleotide diphosphorylase low > 86
Alteromonas macleodii MIT1002 0.58 MIT1002_01344 Quinolinate synthase A 0.39 MIT1002_03008 Nicotinate-nucleotide pyrophosphorylase [carboxylating] — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.58 GFF4 Quinolinate synthetase (EC 2.5.1.72) 0.42 GFF130 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) — —
Pseudomonas putida KT2440 0.58 PP_1231 quinolinate synthase [4Fe-4S] cluster subunit 0.48 PP_0787 quinolinate phosphoribosyltransferase (decarboxylating) monomer 0.89 1
Escherichia coli ECRC99 0.58 KEDOAH_21205 nadA quinolinate synthase NadA 0.37 KEDOAH_17625 nadC carboxylating nicotinate-nucleotide diphosphorylase — —
Enterobacter asburiae PDN3 0.58 EX28DRAFT_2245 quinolinate synthetase (EC 2.5.1.72) 0.41 EX28DRAFT_3702 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.64 17
Escherichia coli ECRC101 0.58 MCAODC_25980 nadA quinolinate synthase NadA 0.37 MCAODC_01045 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.95 2
Escherichia coli Nissle 1917 0.58 ECOLIN_RS03990 quinolinate synthase NadA 0.37 ECOLIN_RS00585 carboxylating nicotinate-nucleotide diphosphorylase 0.52 32
Escherichia coli ECRC100 0.58 OKFHMN_06760 nadA quinolinate synthase NadA 0.37 OKFHMN_10530 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.95 2
Escherichia fergusonii Becca 0.58 EFB2_03356 Quinolinate synthase A 0.37 EFB2_03940 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 86
Dickeya dadantii 3937 0.58 DDA3937_RS06545 quinolinate synthase NadA 0.44 DDA3937_RS17955 carboxylating nicotinate-nucleotide diphosphorylase 0.92 4
Dickeya dianthicola 67-19 0.58 HGI48_RS06595 quinolinate synthase NadA 0.43 HGI48_RS17890 carboxylating nicotinate-nucleotide diphosphorylase low > 71
Escherichia coli ECRC102 0.58 NIAGMN_04810 nadA quinolinate synthase NadA 0.37 NIAGMN_08380 nadC carboxylating nicotinate-nucleotide diphosphorylase — —
Acinetobacter radioresistens SK82 0.58 MPMX26_02602 Quinolinate synthase A 0.44 MPMX26_00042 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.75 7
Escherichia coli ECRC98 0.58 JDDGAC_10415 nadA quinolinate synthase NadA 0.37 JDDGAC_14125 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 86
Dickeya dianthicola ME23 0.58 DZA65_RS06945 quinolinate synthase NadA 0.43 DZA65_RS19035 carboxylating nicotinate-nucleotide diphosphorylase 0.90 2
Pseudomonas sp. S08-1 0.58 OH686_19190 quinolinate synthetase complex, A subunit 0.47 OH686_16520 nicotinate-nucleotide diphosphorylase (carboxylating) 0.97 1
Escherichia coli ECOR27 0.58 NOLOHH_23190 nadA quinolinate synthase NadA 0.37 NOLOHH_02875 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.84 1
Escherichia coli ECRC62 0.58 BNILDI_21185 nadA quinolinate synthase NadA 0.37 BNILDI_08735 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.87 15
Escherichia coli BW25113 0.58 b0750 nadA quinolinate synthetase (NCBI) 0.37 b0109 nadC nicotinate-nucleotide pyrophosphorylase (NCBI) 0.88 2
Enterobacter sp. TBS_079 0.58 MPMX20_01377 Quinolinate synthase A 0.41 MPMX20_00800 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.65 2
Escherichia coli ECOR38 0.58 HEPCGN_01515 nadA quinolinate synthase NadA 0.37 HEPCGN_08510 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.93 1
Escherichia coli BL21 0.58 ECD_00703 quinolinate synthase, subunit A 0.37 ECD_00108 quinolinate phosphoribosyltransferase 0.58 9
Pseudomonas simiae WCS417 0.57 PS417_22385 quinolinate synthase A 0.49 PS417_03925 nicotinate-nucleotide pyrophosphorylase 0.88 1
Klebsiella michiganensis M5al 0.57 BWI76_RS08580 quinolinate synthetase 0.41 BWI76_RS04845 nicotinate-nucleotide pyrophosphorylase 0.83 1
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_1542 quinolinate synthetase 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.84 1
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_626 Quinolinate synthetase (EC 2.5.1.72) 0.50 Pf1N1B4_1153 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.78 1
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_1542 quinolinate synthetase 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) low > 86
Pantoea sp. MT58 0.57 IAI47_13635 quinolinate synthase NadA 0.38 IAI47_15845 carboxylating nicotinate-nucleotide diphosphorylase 0.78 2
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS24025 quinolinate synthase NadA 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.94 1
Escherichia coli HS(pFamp)R (ATCC 700891) 0.57 OHPLBJKB_02963 Quinolinate synthase A 0.37 OHPLBJKB_03552 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 73
Pseudomonas fluorescens SBW25 0.57 PFLU_RS24025 quinolinate synthase NadA 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.91 1
Pseudomonas fluorescens FW300-N2E2 0.57 Pf6N2E2_5553 Quinolinate synthetase (EC 2.5.1.72) 0.49 Pf6N2E2_3346 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.86 1
Pseudomonas sp. RS175 0.57 PFR28_03388 Quinolinate synthase A 0.51 PFR28_00098 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.95 1
Pseudomonas fluorescens FW300-N2C3 0.57 AO356_18145 quinolinate synthase A 0.49 AO356_07370 nicotinate-nucleotide pyrophosphorylase 0.82 1
Pseudomonas fluorescens GW456-L13 0.57 PfGW456L13_1863 Quinolinate synthetase (EC 2.5.1.72) 0.49 PfGW456L13_5082 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.94 1
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_03525 quinolinate synthase A 0.50 AO353_05520 nicotinate-nucleotide pyrophosphorylase 0.90 1
Rahnella sp. WP5 0.56 EX31_RS23525 quinolinate synthase NadA 0.45 EX31_RS03515 carboxylating nicotinate-nucleotide diphosphorylase 0.57 5
Kangiella aquimarina DSM 16071 0.56 B158DRAFT_2453 quinolinate synthetase (EC 2.5.1.72) 0.42 B158DRAFT_2135 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) — —
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_09180 quinolinate synthase 0.45 CSW01_12265 carboxylating nicotinate-nucleotide diphosphorylase low > 62
Bacteroides thetaiotaomicron VPI-5482 0.35 BT3164 quinolinate synthetase A (NCBI ptt file) 0.34 BT1560 nicotinate-nucleotide pyrophosphorylase (NCBI ptt file) — —
Phocaeicola dorei CL03T12C01 0.35 ABI39_RS05755 quinolinate synthase NadA 0.35 ABI39_RS11900 carboxylating nicotinate-nucleotide diphosphorylase — —
Phocaeicola vulgatus CL09T03C04 0.35 HMPREF1058_RS11230 quinolinate synthase NadA 0.35 HMPREF1058_RS15940 carboxylating nicotinate-nucleotide diphosphorylase — —
Bacteroides ovatus ATCC 8483 0.35 BACOVA_02839 quinolinate synthetase complex, A subunit 0.35 BACOVA_04303 nicotinate-nucleotide diphosphorylase (carboxylating) 0.83 30
Pedobacter sp. GW460-11-11-14-LB5 0.34 CA265_RS21180 quinolinate synthase 0.34 CA265_RS14530 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Sphingomonas koreensis DSMZ 15582 0.34 Ga0059261_0051 quinolinate synthetase (EC 2.5.1.72) 0.34 Ga0059261_0061 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS19660 quinolinate synthase NadA 0.37 AMB_RS19655 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Parabacteroides merdae CL09T00C40 0.34 HMPREF1078_RS06555 quinolinate synthase NadA 0.35 HMPREF1078_RS16725 carboxylating nicotinate-nucleotide diphosphorylase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.34 ABZR88_RS20650 quinolinate synthase NadA 0.36 ABZR88_RS15695 carboxylating nicotinate-nucleotide diphosphorylase — —
Bacteroides stercoris CC31F 0.33 HMPREF1181_RS01920 quinolinate synthase NadA 0.35 HMPREF1181_RS10745 carboxylating nicotinate-nucleotide diphosphorylase — —
Synechococcus elongatus PCC 7942 0.32 Synpcc7942_1448 nadA quinolinate synthetase 0.28 Synpcc7942_0951 nadC nicotinate-nucleotide pyrophosphorylase 0.80 1
Fusobacterium nucleatum SB010 0.24 HUW76_10740 quinolinate synthase NadA 0.28 HUW76_10730 carboxylating nicotinate-nucleotide diphosphorylase low > 35
Mycobacterium tuberculosis H37Rv 0.23 Rv1594 Probable quinolinate synthetase NadA 0.29 Rv1596 Probable nicotinate-nucleotide pyrophosphatase NadC — —
Rhizobium sp. OAE497 0.23 ABIE40_RS23255 quinolinate synthase NadA 0.33 ABIE40_RS23265 carboxylating nicotinate-nucleotide diphosphorylase 0.37 10
Rhodospirillum rubrum S1H 0.22 Rru_A1434 Quinolinate synthetase A (NCBI) 0.36 Rru_A1432 Nicotinate-nucleotide pyrophosphorylase (NCBI) 0.93 1
Azospirillum sp. SherDot2 0.22 MPMX19_05670 Quinolinate synthase A 0.32 MPMX19_05672 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] — —
Rhodanobacter denitrificans MT42 0.22 LRK55_RS13615 quinolinate synthase NadA 0.48 LRK55_RS13510 carboxylating nicotinate-nucleotide diphosphorylase low > 63
Agrobacterium fabrum C58 0.22 Atu4098 quinolinate synthetase 0.35 Atu4096 nicotinate-nucleotide pyrophosphorylase 0.97 1
Rhodanobacter denitrificans FW104-10B01 0.22 LRK54_RS13900 quinolinate synthase NadA 0.48 LRK54_RS13795 carboxylating nicotinate-nucleotide diphosphorylase low > 59
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS00620 quinolinate synthase NadA 0.32 A4249_RS00635 carboxylating nicotinate-nucleotide diphosphorylase low > 48
Sinorhizobium meliloti 1021 0.21 SMc02601 quinolinate synthetase 0.30 SMc02598 nicotinate-nucleotide pyrophosphorylase carboxylating protein low > 103
Phaeobacter inhibens DSM 17395 0.21 PGA1_c27790 quinolinate synthetase A 0.27 PGA1_c27810 nicotinate-nucleotide pyrophosphorylase 0.86 1
Methanococcus maripaludis S2 0.20 MMP_RS06390 quinolinate synthase NadA 0.26 MMP_RS04560 carboxylating nicotinate-nucleotide diphosphorylase — —
Methanococcus maripaludis JJ 0.20 MMJJ_RS07960 quinolinate synthase NadA 0.26 MMJJ_RS00575 carboxylating nicotinate-nucleotide diphosphorylase — —
Dechlorosoma suillum PS 0.17 Dsui_1043 quinolinate synthetase complex, A subunit 0.52 Dsui_2901 nicotinate-nucleotide pyrophosphorylase — —
Bifidobacterium breve UCC2003 0.17 BBR_RS16730 quinolinate synthase NadA 0.32 BBR_RS16720 nicotinate-nucleotide diphosphorylase (carboxylating) 0.74 1
Desulfovibrio vulgaris Miyazaki F 0.13 DvMF_0525 quinolinate synthetase (RefSeq) 0.27 DvMF_0524 nicotinate-nucleotide pyrophosphorylase (RefSeq) — —

Not shown: 3 genomes with orthologs for QEN71_RS03060 only; 11 genomes with orthologs for QEN71_RS03065 only