Conservation of cofitness between PFLU_RS02430 and PFLU_RS02000 in Pseudomonas fluorescens SBW25

92 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas fluorescens SBW25 1.0 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 1.0 PFLU_RS02000 penicillin-binding protein 1A 0.83 11
Pseudomonas fluorescens SBW25-INTG 1.00 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 1.00 PFLU_RS02000 penicillin-binding protein 1A low > 109
Pseudomonas simiae WCS417 0.98 PS417_02355 thiamine biosynthesis protein ThiC 0.97 PS417_01955 peptidase low > 88
Pseudomonas syringae pv. syringae B728a 0.95 Psyr_0544 hydroxymethylpyrimidine synthase 0.83 Psyr_0402 Peptidoglycan glycosyltransferase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.95 Psyr_0544 hydroxymethylpyrimidine synthase 0.83 Psyr_0402 Peptidoglycan glycosyltransferase low > 86
Pseudomonas fluorescens FW300-N2E3 0.95 AO353_13010 thiamine biosynthesis protein ThiC 0.88 AO353_12470 peptidase low > 101
Pseudomonas fluorescens FW300-N2E2 0.95 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.84 Pf6N2E2_3761 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 103
Pseudomonas fluorescens FW300-N2C3 0.94 AO356_08810 thiamine biosynthesis protein ThiC 0.88 AO356_09420 peptidase low > 104
Pseudomonas fluorescens FW300-N1B4 0.94 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.88 Pf1N1B4_1544 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 87
Pseudomonas sp. RS175 0.94 PFR28_05091 Phosphomethylpyrimidine synthase 0.87 PFR28_05006 Penicillin-binding protein 1A low > 88
Pseudomonas fluorescens GW456-L13 0.94 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.85 PfGW456L13_282 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 87
Pseudomonas putida KT2440 0.91 PP_4922 Phosphomethylpyrimidine synthase 0.81 PP_5084 penicillin-insensitive transglycosylase/penicillin-sensitive transpeptidase low > 96
Pseudomonas sp. S08-1 0.89 OH686_15885 phosphomethylpyrimidine synthase 0.74 OH686_10055 Multimodular transpeptidase-transglycosylase low > 80
Pseudomonas stutzeri RCH2 0.89 Psest_0477 thiamine biosynthesis protein ThiC 0.69 Psest_3720 penicillin-binding protein, 1A family low > 67
Marinobacter adhaerens HP15 0.80 HP15_453 thiamine biosynthesis protein thiC 0.47 HP15_473 penicillin-binding protein, 1A family — —
Herbaspirillum seropedicae SmR1 0.76 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.34 HSERO_RS20890 penicillin-binding protein 1A — —
Dyella japonica UNC79MFTsu3.2 0.75 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.42 ABZR86_RS11815 penicillin-binding protein 1A low > 74
Dechlorosoma suillum PS 0.75 Dsui_0422 thiamine biosynthesis protein ThiC 0.36 Dsui_1186 penicillin-binding protein, 1A family — —
Paraburkholderia sabiae LMG 24235 0.75 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.36 QEN71_RS28065 penicillin-binding protein 1A low > 153
Burkholderia phytofirmans PsJN 0.75 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.36 BPHYT_RS17915 penicillin-binding protein 1A — —
Paraburkholderia graminis OAS925 0.75 ABIE53_002857 phosphomethylpyrimidine synthase 0.36 ABIE53_003746 penicillin-binding protein 1A low > 113
Castellaniella sp019104865 MT123 0.75 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.31 ABCV34_RS12695 PBP1A family penicillin-binding protein — —
Paraburkholderia bryophila 376MFSha3.1 0.74 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.35 H281DRAFT_05609 penicillin-binding protein 1A low > 103
Lysobacter sp. OAE881 0.74 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.38 ABIE51_RS17190 penicillin-binding protein 1A low > 62
Rhodanobacter sp. FW510-T8 0.74 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.41 OKGIIK_12065 Penicillin-binding protein 1A low > 52
Pontibacter actiniarum KMM 6156, DSM 19842 0.74 CA264_20435 phosphomethylpyrimidine synthase ThiC 0.17 CA264_16345 transglycosylase — —
Acinetobacter radioresistens SK82 0.74 MPMX26_00180 Phosphomethylpyrimidine synthase 0.39 MPMX26_02817 Penicillin-binding protein 1A low > 36
Pedobacter sp. GW460-11-11-14-LB5 0.73 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.15 CA265_RS09720 transglycosylase low > 88
Xanthomonas campestris pv. campestris strain 8004 0.73 Xcc-8004.1066.1 hypothetical protein 0.37 Xcc-8004.1196.1 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.73 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.16 ABZR88_RS02795 penicillin-binding protein 1A low > 71
Pectobacterium carotovorum WPP14 0.72 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.38 HER17_RS01745 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 75
Echinicola vietnamensis KMM 6221, DSM 17526 0.72 Echvi_3567 thiamine biosynthesis protein ThiC 0.17 Echvi_0618 Membrane carboxypeptidase/penicillin-binding protein — —
Ralstonia sp. UNC404CL21Col 0.72 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.33 ABZR87_RS02625 penicillin-binding protein 1A — —
Dickeya dadantii 3937 0.72 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.38 DDA3937_RS19580 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 74
Ralstonia solanacearum PSI07 0.72 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.33 RPSI07_RS10265 penicillin-binding protein 1A — —
Shewanella loihica PV-4 0.71 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.38 Shew_0207 1A family penicillin-binding protein (RefSeq) — —
Rahnella sp. WP5 0.71 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.37 EX31_RS04750 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 89
Ralstonia solanacearum IBSBF1503 0.71 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.32 RALBFv3_RS06970 penicillin-binding protein 1A — —
Ralstonia solanacearum UW163 0.71 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.32 UW163_RS06645 penicillin-binding protein 1A — —
Kangiella aquimarina DSM 16071 0.71 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.39 B158DRAFT_0757 penicillin-binding protein, 1A family — —
Escherichia fergusonii Becca 0.71 EFB2_04617 Phosphomethylpyrimidine synthase 0.37 EFB2_00432 Penicillin-binding protein 1A low > 86
Escherichia coli ECRC101 0.71 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.37 MCAODC_07610 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 87
Escherichia coli ECRC100 0.71 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.37 OKFHMN_17080 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 80
Escherichia coli HS(pFamp)R (ATCC 700891) 0.71 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.37 OHPLBJKB_00307 Penicillin-binding protein 1A low > 73
Escherichia coli ECRC99 0.71 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.37 KEDOAH_11060 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA — —
Escherichia coli ECRC102 0.71 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.37 NIAGMN_14850 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA — —
Escherichia coli ECRC98 0.71 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.37 JDDGAC_20710 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 86
Cupriavidus basilensis FW507-4G11 0.71 RR42_RS01290 thiamine biosynthesis protein ThiC 0.34 RR42_RS19040 penicillin-binding protein — —
Escherichia coli ECOR27 0.71 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.37 NOLOHH_08870 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 75
Escherichia coli ECRC62 0.71 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.37 BNILDI_02650 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 75
Escherichia coli BW25113 0.71 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.37 b3396 mrcA peptidoglycan synthetase; penicillin-binding protein 1A (VIMSS) low > 76
Escherichia coli Nissle 1917 0.71 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.37 ECOLIN_RS19395 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 55
Ralstonia solanacearum GMI1000 0.71 RS_RS00555 phosphomethylpyrimidine synthase 0.33 RS_RS14915 penicillin-binding protein 1A — —
Enterobacter asburiae PDN3 0.71 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.38 EX28DRAFT_4146 penicillin-binding protein, 1A family low > 76
Escherichia coli ECOR38 0.71 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.37 HEPCGN_15900 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 87
Shewanella amazonensis SB2B 0.71 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.39 Sama_3374 penicillin-binding protein 1A (RefSeq) low > 62
Pantoea sp. MT58 0.71 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.38 IAI47_01860 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 76
Escherichia coli BL21 0.71 ECD_03871 phosphomethylpyrimidine synthase 0.37 ECD_03248 penicillin-binding protein 1a, murein transglycosylase and transpeptidase low > 61
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.71 GFF4198 Thiamin biosynthesis protein ThiC 0.38 GFF623 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 78
Enterobacter sp. TBS_079 0.70 MPMX20_00217 Phosphomethylpyrimidine synthase 0.38 MPMX20_04284 Penicillin-binding protein 1A low > 85
Dickeya dianthicola 67-19 0.70 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.37 HGI48_RS19710 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 71
Serratia liquefaciens MT49 0.70 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.37 IAI46_23740 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 86
Klebsiella michiganensis M5al 0.70 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.38 BWI76_RS26125 carboxypeptidase/penicillin-binding protein 1A low > 92
Dickeya dianthicola ME23 0.70 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.37 DZA65_RS20795 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 75
Erwinia tracheiphila SCR3 0.70 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.37 LU632_RS22900 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA — —
Vibrio cholerae E7946 ATCC 55056 0.69 CSW01_00335 phosphomethylpyrimidine synthase 0.37 CSW01_13335 penicillin-binding protein 1A — —
Shewanella oneidensis MR-1 0.69 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.39 SO0280 mrcA penicillin-binding protein 1A (NCBI ptt file) — —
Shewanella sp. ANA-3 0.69 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.39 Shewana3_3900 1A family penicillin-binding protein (RefSeq) — —
Alteromonas macleodii MIT1002 0.68 MIT1002_00097 Phosphomethylpyrimidine synthase 0.36 MIT1002_00454 Penicillin-binding protein 1A low > 70
Variovorax sp. SCN45 0.67 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.32 GFF3310 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.67 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.32 GFF1338 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 90
Acidovorax sp. GW101-3H11 0.66 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.32 Ac3H11_4700 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) — —
Variovorax sp. OAS795 0.66 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.32 ABID97_RS02790 penicillin-binding protein 1A low > 91
Magnetospirillum magneticum AMB-1 0.66 AMB_RS01125 phosphomethylpyrimidine synthase 0.32 AMB_RS16340 penicillin-binding protein 1A — —
Azospirillum brasilense Sp245 0.65 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.31 AZOBR_RS11840 penicillin-binding protein 1A — —
Phaeobacter inhibens DSM 17395 0.64 PGA1_c09110 thiamine biosynthesis protein ThiC 0.25 PGA1_c20280 penicillin-binding protein 1A MrcA low > 62
Caulobacter crescentus NA1000 0.64 CCNA_02109 thiamine biosynthesis protein thiC 0.27 CCNA_01951 multimodular transpeptidase-transglycosylase PbpY low > 66
Agrobacterium fabrum C58 0.64 Atu2569 thiamine biosynthesis protein 0.28 Atu1341 penicillin-binding protein 1a — —
Caulobacter crescentus NA1000 Δfur 0.64 CCNA_02109 thiamine biosynthesis protein thiC 0.27 CCNA_01951 multimodular transpeptidase-transglycosylase PbpY low > 67
Rhodopseudomonas palustris CGA009 0.64 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.28 TX73_012680 penicillin-binding protein 1A — —
Dinoroseobacter shibae DFL-12 0.63 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.27 Dshi_1171 penicillin-binding protein, 1A family (RefSeq) — —
Sinorhizobium meliloti 1021 0.63 SM_b20615 thiamine biosynthesis protein ThiC 0.27 SMc01334 penicillin-binding 1A transmembrane protein — —
Bosea sp. OAE506 0.63 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.27 ABIE41_RS16150 penicillin-binding protein 1A low > 77
Azospirillum sp. SherDot2 0.63 MPMX19_00336 Phosphomethylpyrimidine synthase 0.30 MPMX19_00340 Penicillin-binding protein 1A — —
Sphingomonas koreensis DSMZ 15582 0.63 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.22 Ga0059261_2697 Membrane carboxypeptidase/penicillin-binding protein low > 68
Brevundimonas sp. GW460-12-10-14-LB2 0.62 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.26 A4249_RS04500 penicillin-binding protein 1A — —
Rhodospirillum rubrum S1H 0.60 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.31 Rru_A2147 Penicillin-binding protein 1A (NCBI) — —
Phocaeicola vulgatus CL09T03C04 0.57 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.16 HMPREF1058_RS03825 transglycosylase domain-containing protein — —
Phocaeicola dorei CL03T12C01 0.57 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.16 ABI39_RS17395 transglycosylase domain-containing protein — —
Parabacteroides merdae CL09T00C40 0.57 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC 0.14 HMPREF1078_RS00730 transglycosylase domain-containing protein — —
Bacteroides ovatus ATCC 8483 0.57 BACOVA_02358 thiamine biosynthesis protein ThiC 0.15 BACOVA_02478 transglycosylase — —
Bacteroides thetaiotaomicron VPI-5482 0.56 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.16 BT0743 penicillin-binding protein 1A (PBP-1a) (NCBI ptt file) — —
Bacteroides stercoris CC31F 0.56 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.15 HMPREF1181_RS14855 transglycosylase domain-containing protein — —

Not shown: 1 genomes with orthologs for PFLU_RS02430 only; 5 genomes with orthologs for PFLU_RS02000 only