Conservation of cofitness between GFF66 and GFF2060 in Sphingobium sp. HT1-2

72 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF66 Cobyric acid synthase (EC 6.3.5.10) 1.0 GFF2060 2-isopropylmalate synthase (EC 2.3.3.13) 0.81 4
Sphingomonas koreensis DSMZ 15582 0.72 Ga0059261_0630 adenosylcobyric acid synthase (glutamine-hydrolysing) (EC 6.3.5.10) 0.77 Ga0059261_4031 2-isopropylmalate synthase, yeast type low > 68
Azospirillum brasilense Sp245 0.62 AZOBR_RS09845 cobyric acid synthase 0.56 AZOBR_RS12155 2-isopropylmalate synthase low > 97
Azospirillum sp. SherDot2 0.59 MPMX19_01025 Cobyric acid synthase 0.57 MPMX19_01822 2-isopropylmalate synthase — —
Caulobacter crescentus NA1000 0.57 CCNA_02776 cobyric acid synthase CobQ 0.10 CCNA_01610 2-isopropylmalate synthase low > 66
Caulobacter crescentus NA1000 Δfur 0.57 CCNA_02776 cobyric acid synthase CobQ 0.10 CCNA_01610 2-isopropylmalate synthase low > 67
Sinorhizobium meliloti 1021 0.55 SMc04309 cobyric acid synthase 0.52 SMc02717 2-isopropylmalate synthase — —
Rhizobium sp. OAE497 0.55 ABIE40_RS11175 cobyric acid synthase 0.51 ABIE40_RS13330 2-isopropylmalate synthase 0.95 6
Agrobacterium fabrum C58 0.54 Atu2808 cobyric acid synthase 0.52 Atu2264 2-isopropylmalate synthase low > 89
Bosea sp. OAE506 0.53 ABIE41_RS03845 cobyric acid synthase 0.11 ABIE41_RS13000 2-isopropylmalate synthase — —
Rhodopseudomonas palustris CGA009 0.53 TX73_003715 cobyric acid synthase 0.67 TX73_024250 2-isopropylmalate synthase low > 86
Rhodospirillum rubrum S1H 0.53 Rru_A3381 Cobyric acid synthase CobQ (NCBI) 0.64 Rru_A1461 2-isopropylmalate synthase (RefSeq) low > 58
Xanthobacter sp. DMC5 0.52 GFF372 Cobyric acid synthase 0.11 GFF2400 2-isopropylmalate synthase — —
Magnetospirillum magneticum AMB-1 0.51 AMB_RS01485 cobyric acid synthase 0.54 AMB_RS17550 2-isopropylmalate synthase — —
Phaeobacter inhibens DSM 17395 0.51 PGA1_c24000 cobyric acid synthase CobQ 0.09 PGA1_c26470 2-isopropylmalate synthase LeuA — —
Dinoroseobacter shibae DFL-12 0.50 Dshi_2096 cobyric acid synthase CobQ (RefSeq) 0.10 Dshi_0596 2-isopropylmalate synthase (RefSeq) — —
Pseudomonas putida KT2440 0.45 PP_1677 Adenosyl-cobyric acid synthase 0.61 PP_1025 2-isopropylmalate synthase 0.40 26
Pseudomonas sp. BP01 0.45 JOY50_RS27965 cobyric acid synthase 0.61 JOY50_RS11470 leuA 2-isopropylmalate synthase 0.94 17
Methylophilus sp. DMC18 0.45 GFF1471 Cobyric acid synthase 0.54 GFF446 2-isopropylmalate synthase low > 43
Ralstonia sp. UNC404CL21Col 0.44 ABZR87_RS00040 cobyric acid synthase 0.56 ABZR87_RS22365 2-isopropylmalate synthase low > 80
Paraburkholderia graminis OAS925 0.44 ABIE53_001255 adenosylcobyric acid synthase 0.54 ABIE53_002867 2-isopropylmalate synthase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_00146 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.54 H281DRAFT_00385 2-isopropylmalate synthase low > 103
Ralstonia solanacearum GMI1000 0.44 RS_RS12000 cobyric acid synthase 0.55 RS_RS18695 2-isopropylmalate synthase 2 low > 80
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS04900 cobyric acid synthase 0.55 BPHYT_RS13280 2-isopropylmalate synthase low > 109
Ralstonia solanacearum UW163 0.44 UW163_RS09225 cobyric acid synthase 0.56 UW163_RS17345 2-isopropylmalate synthase — —
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS04445 cobyric acid synthase 0.56 RALBFv3_RS21840 2-isopropylmalate synthase low > 76
Paraburkholderia sabiae LMG 24235 0.44 QEN71_RS25095 cobyric acid synthase 0.51 QEN71_RS01640 2-isopropylmalate synthase low > 153
Ralstonia solanacearum PSI07 0.43 RPSI07_RS12925 cobyric acid synthase 0.55 RPSI07_RS01320 2-isopropylmalate synthase low > 81
Pseudomonas stutzeri RCH2 0.43 Psest_3008 cobyric acid synthase CobQ 0.60 Psest_1277 2-isopropylmalate synthase, yeast type low > 67
Pseudomonas aeruginosa PA14 0.43 IKLFDK_06055 cobyric acid synthase 0.58 IKLFDK_19530 2-isopropylmalate synthase low > 100
Pseudomonas segetis P6 0.43 MPMX49_01822 Cobyric acid synthase 0.59 MPMX49_01526 2-isopropylmalate synthase low > 75
Pseudomonas sp. SVBP6 0.43 COO64_RS07225 cobyric acid synthase 0.61 COO64_RS04630 leuA 2-isopropylmalate synthase low > 93
Pseudomonas sp. DMC3 0.43 GFF2552 Cobyric acid synthase 0.61 GFF4332 2-isopropylmalate synthase low > 89
Pseudomonas fluorescens FW300-N2E2 0.42 Pf6N2E2_5742 Cobyric acid synthase (EC 6.3.5.10) 0.61 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) 0.29 90
Pseudomonas sp. S08-1 0.42 OH686_04965 cobyric acid synthase CobQ 0.59 OH686_17570 2-isopropylmalate synthase low > 80
Shewanella sp. ANA-3 0.42 Shewana3_3275 cobyric acid synthase (RefSeq) 0.09 Shewana3_3761 2-isopropylmalate synthase (RefSeq) low > 73
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4238 Cobyric acid synthase (EC 6.3.5.10) 0.60 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) low > 87
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS16075 cobyric acid synthase 0.58 RR42_RS21205 2-isopropylmalate synthase low > 128
Pseudomonas fluorescens FW300-N2C3 0.42 AO356_19160 cobyric acid synthase 0.61 AO356_06550 2-isopropylmalate synthase 0.43 50
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_02615 cobyric acid synthase 0.61 AO353_15925 2-isopropylmalate synthase 0.38 53
Pseudomonas syringae pv. syringae B728a 0.42 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.60 Psyr_1257 2-isopropylmalate synthase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.42 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.60 Psyr_1257 2-isopropylmalate synthase 0.45 30
Vibrio cholerae E7946 ATCC 55056 0.42 CSW01_17810 cobyric acid synthase CobQ 0.09 CSW01_12595 2-isopropylmalate synthase low > 62
Dechlorosoma suillum PS 0.41 Dsui_0542 cobyric acid synthase CobQ 0.55 Dsui_3227 2-isopropylmalate synthase low > 51
Shewanella loihica PV-4 0.41 Shew_0717 cobyric acid synthase (RefSeq) 0.10 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.79 21
Pseudomonas simiae WCS417 0.41 PS417_20040 cobyric acid synthase 0.60 PS417_23110 2-isopropylmalate synthase low > 88
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3711 Cobyric acid synthase (EC 6.3.5.10) 0.61 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) 0.33 72
Pseudomonas fluorescens SBW25 0.41 PFLU_RS22005 cobyric acid synthase 0.60 PFLU_RS24765 2-isopropylmalate synthase low > 109
Lysobacter sp. OAE881 0.41 ABIE51_RS04965 cobyric acid synthase 0.12 ABIE51_RS17570 2-isopropylmalate synthase low > 62
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS22005 cobyric acid synthase 0.60 PFLU_RS24765 2-isopropylmalate synthase low > 109
Pseudomonas lactucae CFBP13502 0.41 GEMAOFIL_04205 Cobyric acid synthase 0.60 GEMAOFIL_04774 2-isopropylmalate synthase low > 93
Shewanella oneidensis MR-1 0.41 SO1038 cobQ cobyric acid synthase CobQ (NCBI ptt file) 0.09 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.71 13
Rhodanobacter sp. FW510-T8 0.41 OKGIIK_05500 cobyric acid synthase 0.09 OKGIIK_13575 leuA 2-isopropylmalate synthase low > 53
Pseudomonas sp. RS175 0.41 PFR28_03204 Cobyric acid synthase 0.61 PFR28_00305 2-isopropylmalate synthase 0.30 71
Herbaspirillum seropedicae SmR1 0.40 HSERO_RS13230 cobyric acid synthase 0.60 HSERO_RS17185 2-isopropylmalate synthase low > 78
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS10900 cobyric acid synthase 0.10 ABZR86_RS15970 2-isopropylmalate synthase low > 74
Shewanella amazonensis SB2B 0.39 Sama_0765 cobyric acid synthase (RefSeq) 0.09 Sama_0335 2-isopropylmalate synthase (RefSeq) low > 62
Mycobacterium tuberculosis H37Rv 0.38 Rv0255c Probable cobyric acid synthase CobQ1 0.51 Rv3710 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) — —
Klebsiella michiganensis M5al 0.38 BWI76_RS23010 cobyric acid synthase CobQ 0.53 BWI76_RS22105 2-isopropylmalate synthase low > 92
Klebsiella pneumoniae MKP103 0.37 KDGMDA_03575 cobyric acid synthase 0.54 KDGMDA_02770 2-isopropylmalate synthase low > 95
Synechococcus elongatus PCC 7942 0.34 Synpcc7942_0211 cobQ cobyric acid synthase 0.09 Synpcc7942_1410 leuA 2-isopropylmalate synthase — —
Synechocystis sp000284455 PCC 6803 0.34 SGL_RS15620 cobyric acid synthase CobQ 0.08 SGL_RS12850 2-isopropylmalate synthase — —
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS01395 cobyric acid synthase 0.10 HMPREF1058_RS14545 2-isopropylmalate synthase low > 67
Desulfovibrio vulgaris Hildenborough JW710 0.33 DVU0816 cobQ cobyric acid synthase CobQ (TIGR) 0.10 DVU2981 leuA 2-isopropylmalate synthase (TIGR) 0.60 41
Phocaeicola dorei CL03T12C01 0.33 ABI39_RS15660 cobyric acid synthase 0.10 ABI39_RS10195 2-isopropylmalate synthase low > 72
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS00930 cobyric acid synthase 0.11 HMPREF1078_RS16665 2-isopropylmalate synthase low > 61
Methanococcus maripaludis JJ 0.33 MMJJ_RS08095 cobyric acid synthase CobQ 0.10 MMJJ_RS08870 2-isopropylmalate synthase low > 28
Methanococcus maripaludis S2 0.32 MMP_RS06255 cobyric acid synthase CobQ 0.09 MMP_RS05500 2-isopropylmalate synthase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.32 GFF3998 Cobyric acid synthase (EC 6.3.5.10) 0.56 GFF4280 2-isopropylmalate synthase (EC 2.3.3.13) low > 90
Variovorax sp. SCN45 0.31 GFF426 Cobyric acid synthase (EC 6.3.5.10) 0.55 GFF1164 2-isopropylmalate synthase (EC 2.3.3.13) 0.75 64
Acidovorax sp. GW101-3H11 0.31 Ac3H11_999 Cobyric acid synthase (EC 6.3.5.10) 0.51 Ac3H11_5000 2-isopropylmalate synthase (EC 2.3.3.13) low > 79
Desulfovibrio vulgaris Miyazaki F 0.31 DvMF_2864 cobyric acid synthase (RefSeq) 0.12 DvMF_1791 2-isopropylmalate synthase (RefSeq) — —
Variovorax sp. OAS795 0.30 ABID97_RS17340 cobyric acid synthase 0.55 ABID97_RS14905 2-isopropylmalate synthase low > 91

Not shown: 2 genomes with orthologs for GFF66 only; 39 genomes with orthologs for GFF2060 only