Conservation of cofitness between PGA1_c12150 and PGA1_c11870 in Phaeobacter inhibens DSM 17395

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Phaeobacter inhibens DSM 17395 1.0 PGA1_c12150 dihydroorotate dehydrogenase PyrD 1.0 PGA1_c11870 serine hydroxymethyltransferase GlyA 0.88 9
Dinoroseobacter shibae DFL-12 0.70 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.82 Dshi_0821 Glycine hydroxymethyltransferase (RefSeq) 0.76 22
Azospirillum sp. SherDot2 0.47 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) 0.69 MPMX19_00727 Serine hydroxymethyltransferase 2 — —
Sinorhizobium meliloti 1021 0.47 SMc02245 dihydroorotate dehydrogenase 2 0.72 SMc01770 serine hydroxymethyltransferase 0.84 41
Agrobacterium fabrum C58 0.46 Atu0486 dihydroorotate dehydrogenase 0.73 Atu1165 serine hydroxymethyltransferase — —
Magnetospirillum magneticum AMB-1 0.45 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase 0.68 AMB_RS11815 serine hydroxymethyltransferase — —
Azospirillum brasilense Sp245 0.44 AZOBR_RS13520 dihydroorotate dehydrogenase 0.69 AZOBR_RS10015 serine hydroxymethyltransferase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.44 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase 0.61 A4249_RS06040 serine hydroxymethyltransferase — —
Rhizobium sp. OAE497 0.44 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase 0.71 ABIE40_RS06715 serine hydroxymethyltransferase — —
Caulobacter crescentus NA1000 0.42 CCNA_00562 dihydroorotate dehydrogenase 0.68 CCNA_01419 serine hydroxymethyltransferase — —
Caulobacter crescentus NA1000 Δfur 0.42 CCNA_00562 dihydroorotate dehydrogenase 0.68 CCNA_01419 serine hydroxymethyltransferase low > 67
Rhodospirillum rubrum S1H 0.41 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.72 Rru_A1827 Glycine hydroxymethyltransferase (NCBI) 0.72 40
Rhodopseudomonas palustris CGA009 0.41 TX73_004110 quinone-dependent dihydroorotate dehydrogenase 0.67 TX73_014115 serine hydroxymethyltransferase — —
Bosea sp. OAE506 0.40 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.72 ABIE41_RS19780 serine hydroxymethyltransferase — —
Pseudomonas stutzeri RCH2 0.38 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.59 Psest_3404 Glycine/serine hydroxymethyltransferase — —
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase 0.59 OKGIIK_11440 glyA serine hydroxymethyltransferase — —
Acidovorax sp. GW101-3H11 0.37 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.57 Ac3H11_2921 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Pedobacter sp. GW460-11-11-14-LB5 0.37 CA265_RS14005 dihydroorotate dehydrogenase (quinone) 0.48 CA265_RS19165 serine hydroxymethyltransferase — —
Sphingomonas koreensis DSMZ 15582 0.37 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) 0.63 Ga0059261_1986 Glycine/serine hydroxymethyltransferase — —
Rhodanobacter denitrificans MT42 0.37 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase 0.58 LRK55_RS04400 serine hydroxymethyltransferase — —
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase 0.58 LRK54_RS04625 serine hydroxymethyltransferase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.37 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 0.47 Echvi_1188 Glycine/serine hydroxymethyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.57 PFLU_RS26195 serine hydroxymethyltransferase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.36 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase 0.48 ABZR88_RS00640 serine hydroxymethyltransferase — —
Pseudomonas fluorescens SBW25 0.36 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.57 PFLU_RS26195 serine hydroxymethyltransferase — —
Dyella japonica UNC79MFTsu3.2 0.36 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase 0.59 ABZR86_RS10715 serine hydroxymethyltransferase — —
Castellaniella sp019104865 MT123 0.36 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase 0.55 ABCV34_RS06400 serine hydroxymethyltransferase — —
Pseudomonas fluorescens GW456-L13 0.36 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.57 PfGW456L13_1451 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Variovorax sp. SCN45 0.36 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) 0.55 GFF560 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Pseudomonas sp. S08-1 0.36 OH686_03120 dihydroorotate dehydrogenase (fumarate) 0.58 OH686_16230 Serine hydroxymethyltransferase — —
Pseudomonas simiae WCS417 0.36 PS417_20935 dihydroorotate dehydrogenase 0.58 PS417_24280 serine hydroxymethyltransferase — —
Shewanella oneidensis MR-1 0.36 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.57 SO3471 glyA serine hydroxymethyltransferase (NCBI ptt file) 0.85 28
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.57 GFF5152 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.58 AO353_14020 serine hydroxymethyltransferase — —
Pseudomonas fluorescens FW300-N1B4 0.36 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.58 Pf1N1B4_2778 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Shewanella sp. ANA-3 0.36 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.57 Shewana3_1094 glyA serine hydroxymethyltransferase (RefSeq) 0.83 54
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.58 Pf6N2E2_5082 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Ralstonia solanacearum UW163 0.36 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase 0.58 UW163_RS00670 serine hydroxymethyltransferase — —
Ralstonia solanacearum IBSBF1503 0.36 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase 0.58 RALBFv3_RS12895 serine hydroxymethyltransferase — —
Acinetobacter radioresistens SK82 0.36 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.55 MPMX26_02049 Serine hydroxymethyltransferase — —
Pseudomonas fluorescens FW300-N2C3 0.35 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.57 AO356_15725 serine hydroxymethyltransferase — —
Pseudomonas sp. RS175 0.35 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.58 PFR28_03786 Serine hydroxymethyltransferase — —
Variovorax sp. OAS795 0.35 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase 0.55 ABID97_RS17890 serine hydroxymethyltransferase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase 0.59 ABZR87_RS08955 serine hydroxymethyltransferase — —
Alteromonas macleodii MIT1002 0.35 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.54 MIT1002_02702 Serine hydroxymethyltransferase low > 70
Pontibacter actiniarum KMM 6156, DSM 19842 0.35 CA264_00865 dihydroorotate dehydrogenase (quinone) 0.46 CA264_17045 serine hydroxymethyltransferase low > 74
Paraburkholderia graminis OAS925 0.35 ABIE53_001954 dihydroorotate dehydrogenase 0.65 ABIE53_006138 glycine hydroxymethyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_2106 dihydroorotate oxidase A 0.57 Psyr_4270 serine hydroxymethyltransferase — —
Ralstonia solanacearum PSI07 0.35 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase 0.57 RPSI07_RS20330 serine hydroxymethyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_2106 dihydroorotate oxidase A 0.57 Psyr_4270 serine hydroxymethyltransferase — —
Dechlorosoma suillum PS 0.35 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 0.59 Dsui_2254 glycine/serine hydroxymethyltransferase — —
Ralstonia solanacearum GMI1000 0.35 RS_RS08160 dihydroorotate dehydrogenase (quinone) 0.66 RS_RS17460 serine hydroxymethyltransferase — —
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS08565 dihydroorotate dehydrogenase 0.66 BPHYT_RS25180 serine hydroxymethyltransferase low > 109
Paraburkholderia sabiae LMG 24235 0.34 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase 0.66 QEN71_RS08310 serine hydroxymethyltransferase — —
Pseudomonas putida KT2440 0.34 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.58 PP_0671 serine hydroxymethyltransferase — —
Cupriavidus basilensis FW507-4G11 0.34 RR42_RS07465 dihydroorotate dehydrogenase 0.58 RR42_RS15485 serine hydroxymethyltransferase — —
Dickeya dadantii 3937 0.34 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.56 DDA3937_RS15600 serine hydroxymethyltransferase — —
Herbaspirillum seropedicae SmR1 0.34 HSERO_RS16155 dihydroorotate dehydrogenase 0.59 HSERO_RS06140 serine hydroxymethyltransferase — —
Xanthomonas campestris pv. campestris strain 8004 0.34 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.58 Xcc-8004.4398.1 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Paraburkholderia bryophila 376MFSha3.1 0.34 H281DRAFT_00743 dihydroorotate oxidase A 0.66 H281DRAFT_02468 serine hydroxymethyltransferase — —
Pantoea sp. MT58 0.33 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.56 IAI47_04960 serine hydroxymethyltransferase — —
Klebsiella michiganensis M5al 0.33 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.52 BWI76_RS21225 serine hydroxymethyltransferase — —
Vibrio cholerae E7946 ATCC 55056 0.33 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.64 CSW01_15340 serine hydroxymethyltransferase low > 62
Dickeya dianthicola ME23 0.33 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.56 DZA65_RS16775 serine hydroxymethyltransferase — —
Pectobacterium carotovorum WPP14 0.33 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.56 HER17_RS01990 serine hydroxymethyltransferase low > 75
Shewanella loihica PV-4 0.33 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.58 Shew_1185 glyA serine hydroxymethyltransferase (RefSeq) 0.76 24
Escherichia fergusonii Becca 0.33 EFB2_03126 Dihydroorotate dehydrogenase (quinone) 0.52 EFB2_01345 Serine hydroxymethyltransferase — —
Escherichia coli Nissle 1917 0.33 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase 0.52 ECOLIN_RS14440 serine hydroxymethyltransferase — —
Enterobacter sp. TBS_079 0.33 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.52 MPMX20_03420 Serine hydroxymethyltransferase — —
Shewanella amazonensis SB2B 0.33 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.58 Sama_1014 glyA serine hydroxymethyltransferase (RefSeq) low > 62
Enterobacter asburiae PDN3 0.33 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) 0.52 EX28DRAFT_0099 Glycine/serine hydroxymethyltransferase — —
Kangiella aquimarina DSM 16071 0.33 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) 0.57 B158DRAFT_1908 Glycine/serine hydroxymethyltransferase — —
Escherichia coli ECOR38 0.33 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 0.52 HEPCGN_20655 glyA serine hydroxymethyltransferase low > 85
Dickeya dianthicola 67-19 0.33 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.56 HGI48_RS15700 serine hydroxymethyltransferase — —
Escherichia coli BW25113 0.33 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.52 b2551 glyA serine hydroxymethyltransferase (NCBI) — —
Escherichia coli BL21 0.33 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.52 ECD_02443 serine hydroxymethyltransferase low > 60
Escherichia coli ECRC62 0.33 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.52 BNILDI_11985 glyA serine hydroxymethyltransferase — —
Escherichia coli ECOR27 0.33 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 0.52 NOLOHH_13185 glyA serine hydroxymethyltransferase low > 57
Escherichia coli ECRC101 0.33 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 0.52 OKFHMN_21510 glyA serine hydroxymethyltransferase — —
Erwinia tracheiphila SCR3 0.33 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.55 LU632_RS17915 serine hydroxymethyltransferase — —
Escherichia coli ECRC101 0.33 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.52 MCAODC_12040 glyA serine hydroxymethyltransferase — —
Escherichia coli ECRC102 0.33 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.52 NIAGMN_19280 glyA serine hydroxymethyltransferase — —
Escherichia coli ECRC98 0.33 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase 0.52 JDDGAC_25175 glyA serine hydroxymethyltransferase — —
Lysobacter sp. OAE881 0.33 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase 0.59 ABIE51_RS04620 serine hydroxymethyltransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.33 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 0.52 OHPLBJKB_01156 Serine hydroxymethyltransferase low > 73
Escherichia coli ECRC99 0.33 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase 0.52 KEDOAH_06710 glyA serine hydroxymethyltransferase — —
Rahnella sp. WP5 0.32 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.55 EX31_RS20585 serine hydroxymethyltransferase — —
Serratia liquefaciens MT49 0.32 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.55 IAI46_19395 serine hydroxymethyltransferase — —
Mycobacterium tuberculosis H37Rv 0.32 Rv2139 Probable dihydroorotate dehydrogenase PyrD 0.52 Rv0070c Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.31 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.53 GFF2447 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_0290 pyrD dihydroorotate dehydrogenase 2 0.60 Synpcc7942_0282 glyA serine hydroxymethyltransferase — —

Not shown: 1 genomes with orthologs for PGA1_c12150 only; 9 genomes with orthologs for PGA1_c11870 only