Conservation of cofitness between CSW01_01850 and CSW01_07190 in Vibrio cholerae E7946 ATCC 55056

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01850 protease modulator HflC 1.0 CSW01_07190 transcriptional regulator FNR 0.52 10
Serratia liquefaciens MT49 0.51 IAI46_01640 protease modulator HflC 0.86 IAI46_13260 FNR family transcription factor low > 86
Enterobacter sp. TBS_079 0.51 MPMX20_00456 Modulator of FtsH protease HflC 0.85 MPMX20_02035 Fumarate and nitrate reduction regulatory protein low > 85
Shewanella oneidensis MR-1 0.50 SO0606 hflC hflC protein (NCBI ptt file) 0.76 SO2356 etrA electron transport regulator a (NCBI ptt file) low > 76
Escherichia coli ECRC102 0.50 NIAGMN_10090 hflC protease modulator HflC 0.85 NIAGMN_26410 fnr fumarate/nitrate reduction transcriptional regulator Fnr
Escherichia coli ECOR38 0.50 HEPCGN_10470 hflC protease modulator HflC 0.85 HEPCGN_25925 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 87
Escherichia coli ECRC101 0.50 MCAODC_02755 hflC protease modulator HflC 0.85 MCAODC_16030 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 87
Escherichia coli ECOR27 0.50 NOLOHH_04505 hflC protease modulator HflC 0.85 NOLOHH_19940 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 75
Escherichia coli Nissle 1917 0.50 ECOLIN_RS24245 protease modulator HflC 0.85 ECOLIN_RS08005 fumarate/nitrate reduction transcriptional regulator Fnr
Escherichia coli ECRC100 0.50 OKFHMN_12240 hflC protease modulator HflC 0.85 OKFHMN_02240 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 80
Escherichia coli ECRC98 0.50 JDDGAC_15880 hflC protease modulator HflC 0.85 JDDGAC_04785 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.50 OHPLBJKB_03867 Modulator of FtsH protease HflC 0.85 OHPLBJKB_02348 Fumarate and nitrate reduction regulatory protein low > 73
Escherichia coli BW25113 0.50 b4175 hflC modulator for HflB protease specific for phage lambda cII repressor (NCBI) 0.85 b1334 fnr DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) low > 76
Escherichia coli ECRC62 0.50 BNILDI_06985 hflC protease modulator HflC 0.85 BNILDI_18090 fnr fumarate/nitrate reduction transcriptional regulator Fnr 0.69 58
Escherichia fergusonii Becca 0.50 EFB2_04360 Modulator of FtsH protease HflC 0.85 EFB2_02593 Fumarate and nitrate reduction regulatory protein low > 86
Escherichia coli ECRC99 0.50 KEDOAH_15915 hflC protease modulator HflC 0.85 KEDOAH_26530 fnr fumarate/nitrate reduction transcriptional regulator Fnr
Alteromonas macleodii MIT1002 0.50 MIT1002_03785 Modulator of FtsH protease HflC 0.57 MIT1002_02137 Fumarate and nitrate reduction regulatory protein low > 70
Pantoea sp. MT58 0.50 IAI47_02605 protease modulator HflC 0.85 IAI47_09580 FNR family transcription factor low > 76
Erwinia tracheiphila SCR3 0.50 LU632_RS02070 hflC protease modulator HflC 0.83 LU632_RS11420 FNR family transcription factor low > 74
Klebsiella michiganensis M5al 0.50 BWI76_RS02550 protease modulator HflC 0.85 BWI76_RS16185 transcriptional regulator FNR
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF828 HflC protein 0.85 GFF2656 Fumarate and nitrate reduction regulatory protein low > 78
Pectobacterium carotovorum WPP14 0.50 HER17_RS02600 protease modulator HflC 0.86 HER17_RS10525 fumarate/nitrate reduction transcriptional regulator Fnr low > 75
Shewanella sp. ANA-3 0.50 Shewana3_0600 HflC protein (RefSeq) 0.77 Shewana3_2115 fumarate/nitrate reduction transcriptional regulator (RefSeq)
Shewanella loihica PV-4 0.49 Shew_0569 HflC protein (RefSeq) 0.76 Shew_1993 fumarate/nitrate reduction transcriptional regulator (RefSeq)
Erwinia amylovora T8 0.49 OLJFJH_02485 protease modulator HflC 0.83 OLJFJH_13925 transcriptional regulator FNR low > 58
Rahnella sp. WP5 0.49 EX31_RS08805 protease modulator HflC 0.86 EX31_RS07200 FNR family transcription factor low > 89
Dickeya dianthicola 67-19 0.49 HGI48_RS18530 protease modulator HflC 0.86 HGI48_RS10900 fumarate/nitrate reduction transcriptional regulator Fnr low > 71
Dickeya dianthicola ME23 0.49 DZA65_RS19665 protease modulator HflC 0.86 DZA65_RS11360 fumarate/nitrate reduction transcriptional regulator Fnr low > 75
Shewanella amazonensis SB2B 0.49 Sama_3022 hflC protein (RefSeq) 0.76 Sama_1799 fumarate/nitrate reduction transcriptional regulator (RefSeq) low > 62
Enterobacter asburiae PDN3 0.48 EX28DRAFT_3372 HflC protein 0.84 EX28DRAFT_1540 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases low > 76
Dickeya dadantii 3937 0.48 DDA3937_RS18595 protease modulator HflC 0.86 DDA3937_RS10950 fumarate/nitrate reduction transcriptional regulator Fnr
Kangiella aquimarina DSM 16071 0.40 B158DRAFT_1955 HflC protein 0.56 B158DRAFT_1982 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases low > 40
Marinobacter adhaerens HP15 0.36 HP15_2496 HflC 0.41 HP15_634 transcriptional regulator, Crp/Fnr family low > 73
Dechlorosoma suillum PS 0.35 Dsui_3134 membrane protease subunit, stomatin/prohibitin 0.40 Dsui_1646 cAMP-binding protein
Rhodanobacter sp. FW510-T8 0.34 OKGIIK_06645 hflC protease modulator HflC 0.37 OKGIIK_00820 CRP-like protein Clp low > 52
Pseudomonas syringae pv. syringae B728a 0.33 Psyr_0575 protease FtsH subunit HflC 0.54 Psyr_3425 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.33 Psyr_0575 protease FtsH subunit HflC 0.54 Psyr_3425 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp
Pseudomonas fluorescens FW300-N1B4 0.33 Pf1N1B4_1409 HflC protein 0.53 Pf1N1B4_3867 Fumarate and nitrate reduction regulatory protein
Pseudomonas sp. SVBP6 0.33 COO64_RS17915 hflC protease modulator HflC 0.52 COO64_RS18640 fnrA Crp/Fnr family transcriptional regulator FnrA low > 93
Methylophilus sp. DMC18 0.33 GFF1224 Modulator of FtsH protease HflC 0.38 GFF1089 Transcriptional activator protein Anr low > 43
Pseudomonas fluorescens GW456-L13 0.33 PfGW456L13_151 HflC protein 0.54 PfGW456L13_4071 Fumarate and nitrate reduction regulatory protein low > 87
Pseudomonas fluorescens FW300-N2E3 0.33 AO353_13160 membrane protease HflC 0.53 AO353_00660 transcriptional regulator low > 101
Dyella japonica UNC79MFTsu3.2 0.33 ABZR86_RS08350 protease modulator HflC 0.25 ABZR86_RS04345 cyclic nucleotide-binding domain-containing protein low > 74
Pseudomonas fluorescens FW300-N2E2 0.33 Pf6N2E2_3611 HflC protein 0.53 Pf6N2E2_2323 Fumarate and nitrate reduction regulatory protein low > 103
Pseudomonas fluorescens FW300-N2C3 0.33 AO356_08640 membrane protease HflC 0.53 AO356_02485 transcriptional regulator low > 104
Pseudomonas aeruginosa PA14 0.32 IKLFDK_28835 protease modulator HflC 0.53 IKLFDK_07375 transcriptional regulator Anr
Pseudomonas fluorescens SBW25 0.32 PFLU_RS02585 protease modulator HflC 0.53 PFLU_RS22395 fumarate/nitrate reduction transcriptional regulator Fnr low > 109
Pseudomonas fluorescens SBW25-INTG 0.32 PFLU_RS02585 protease modulator HflC 0.53 PFLU_RS22395 fumarate/nitrate reduction transcriptional regulator Fnr low > 109
Pseudomonas sp. DMC3 0.32 GFF3223 Modulator of FtsH protease HflC 0.54 GFF711 Transcriptional activator protein Anr
Rhodanobacter sp000427505 FW510-R12 0.32 LRK53_RS09540 protease modulator HflC 0.35 LRK53_RS14515 cyclic nucleotide-binding domain-containing protein low > 60
Rhodanobacter denitrificans FW104-10B01 0.32 LRK54_RS00615 protease modulator HflC 0.35 LRK54_RS05830 helix-turn-helix domain-containing protein low > 59
Castellaniella sp019104865 MT123 0.31 ABCV34_RS02665 protease modulator HflC 0.34 ABCV34_RS06835 helix-turn-helix domain-containing protein
Rhodanobacter denitrificans MT42 0.31 LRK55_RS00385 protease modulator HflC 0.35 LRK55_RS05585 helix-turn-helix domain-containing protein low > 63
Pseudomonas sp. BP01 0.31 JOY50_RS17245 hflC protease modulator HflC 0.52 JOY50_RS00125 fnrA Crp/Fnr family transcriptional regulator FnrA low > 84
Pseudomonas stutzeri RCH2 0.31 Psest_0686 Membrane protease subunits, stomatin/prohibitin homologs 0.53 Psest_2538 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
Pseudomonas putida KT2440 0.31 PP_4891 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex 0.52 PP_4265 DNA-binding transcriptional dual regulator low > 96
Pseudomonas sp. S08-1 0.31 OH686_09455 HflC protein 0.53 OH686_02245 Fumarate and nitrate reduction regulatory protein low > 80
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.3954.1 HflC protein 0.22 Xcc-8004.2952.1 transcriptional regulator, Crp/Fnr family low > 74
Pseudomonas sp. RS175 0.30 PFR28_05124 Modulator of FtsH protease HflC 0.53 PFR28_01079 Transcriptional activator protein Anr
Lysobacter sp. OAE881 0.30 ABIE51_RS06555 protease modulator HflC 0.37 ABIE51_RS03805 fumarate/nitrate reduction transcriptional regulator Fnr low > 62
Herbaspirillum seropedicae SmR1 0.30 HSERO_RS14760 membrane protein 0.41 HSERO_RS16020 transcriptional regulator
Pseudomonas simiae WCS417 0.29 PS417_02505 membane protease HflC 0.53 PS417_20785 transcriptional regulator
Ralstonia solanacearum IBSBF1503 0.29 RALBFv3_RS15315 protease modulator HflC 0.38 RALBFv3_RS15650 fumarate/nitrate reduction transcriptional regulator Fnr
Ralstonia solanacearum UW163 0.29 UW163_RS12780 protease modulator HflC 0.38 UW163_RS13110 fumarate/nitrate reduction transcriptional regulator Fnr
Ralstonia solanacearum GMI1000 0.29 RS_RS06125 protease modulator HflC 0.38 RS_RS06430 fumarate/nitrate reduction transcriptional regulator Fnr
Ralstonia solanacearum PSI07 0.29 RPSI07_RS18060 protease modulator HflC 0.38 RPSI07_RS17705 fumarate/nitrate reduction transcriptional regulator Fnr low > 81
Cupriavidus basilensis FW507-4G11 0.29 RR42_RS13100 membrane protein 0.40 RR42_RS12875 transcriptional regulator
Ralstonia sp. UNC404CL21Col 0.29 ABZR87_RS10955 protease modulator HflC 0.39 ABZR87_RS11180 fumarate/nitrate reduction transcriptional regulator Fnr low > 80
Magnetospirillum magneticum AMB-1 0.28 AMB_RS17655 protease modulator HflC 0.22 AMB_RS22105 transcriptional regulator
Phaeobacter inhibens DSM 17395 0.28 PGA1_c23700 protein HflC 0.18 PGA1_c30140 transcriptional activator protein FnrL low > 62
Acidovorax sp. GW101-3H11 0.26 Ac3H11_1802 HflC protein 0.38 Ac3H11_975 transcriptional regulator, Crp/Fnr family
Azospirillum sp. SherDot2 0.26 MPMX19_01250 Modulator of FtsH protease HflC 0.26 MPMX19_00212 Nitrogen fixation regulation protein FixK
Variovorax sp. SCN45 0.25 GFF1003 HflC protein 0.22 GFF6947 transcriptional regulator, Crp/Fnr family low > 127
Desulfovibrio vulgaris Miyazaki F 0.24 DvMF_2675 HflC protein (RefSeq) 0.14 DvMF_0993 transcriptional regulator, Crp/Fnr family (RefSeq) low > 51
Dinoroseobacter shibae DFL-12 0.24 Dshi_2735 HflC protein (RefSeq) 0.15 Dshi_0660 transcriptional regulator, Crp/Fnr family (RefSeq) low > 64
Rhodospirillum rubrum S1H 0.24 Rru_A2202 HflC (NCBI) 0.22 Rru_A3322 Transcriptional Regulator, Crp/Fnr family (NCBI)
Azospirillum brasilense Sp245 0.24 AZOBR_RS06525 membrane protein 0.26 AZOBR_RS01145 Crp/Fnr family transcriptional regulator 0.50 28
Desulfovibrio vulgaris Hildenborough JW710 0.23 DVU0683 hflC protein, putative (TIGR) 0.14 DVU2547 transcriptional regulator, putative (TIGR) low > 55
Agrobacterium fabrum C58 0.22 Atu2044 HFLC protein 0.19 Atu1602 transcriptional activator, Crp family low > 89
Hydrogenophaga sp. GW460-11-11-14-LB1 0.22 GFF4855 HflC protein 0.39 GFF4142 transcriptional regulator, Crp/Fnr family low > 90
Paraburkholderia graminis OAS925 0.21 ABIE53_002734 membrane protease subunit HflC 0.35 ABIE53_004332 CRP/FNR family transcriptional regulator low > 113
Echinicola vietnamensis KMM 6221, DSM 17526 0.21 Echvi_2032 HflC protein 0.17 Echvi_2881 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases low > 79
Paraburkholderia bryophila 376MFSha3.1 0.20 H281DRAFT_00524 protease FtsH subunit HflC 0.36 H281DRAFT_01640 transcriptional regulator, Crp/Fnr family
Paraburkholderia sabiae LMG 24235 0.19 QEN71_RS06015 protease modulator HflC 0.38 QEN71_RS17975 helix-turn-helix domain-containing protein low > 153
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS12540 membrane protein 0.38 BPHYT_RS31300 Crp/Fnr family transcriptional regulator
Sphingomonas koreensis DSMZ 15582 0.14 Ga0059261_1381 Membrane protease subunits, stomatin/prohibitin homologs 0.16 Ga0059261_1530 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases low > 68

Not shown: 7 genomes with orthologs for CSW01_01850 only; 1 genomes with orthologs for CSW01_07190 only