Conservation of cofitness between CSW01_02450 and CSW01_04820 in Vibrio cholerae E7946 ATCC 55056

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02450 pyrroline-5-carboxylate reductase 1.0 CSW01_04820 serine hydroxymethyltransferase 0.86 11
Serratia liquefaciens MT49 0.69 IAI46_21415 pyrroline-5-carboxylate reductase 0.81 IAI46_19395 serine hydroxymethyltransferase — —
Pectobacterium carotovorum WPP14 0.69 HER17_RS03805 pyrroline-5-carboxylate reductase 0.81 HER17_RS05950 serine hydroxymethyltransferase — —
Dickeya dadantii 3937 0.68 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.81 DDA3937_RS15600 serine hydroxymethyltransferase — —
Dickeya dianthicola 67-19 0.68 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.81 HGI48_RS15700 serine hydroxymethyltransferase — —
Dickeya dianthicola ME23 0.67 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.81 DZA65_RS16775 serine hydroxymethyltransferase — —
Rahnella sp. WP5 0.65 EX31_RS02690 pyrroline-5-carboxylate reductase 0.80 EX31_RS20585 serine hydroxymethyltransferase — —
Alteromonas macleodii MIT1002 0.60 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.73 MIT1002_02702 Serine hydroxymethyltransferase 0.87 54
Shewanella oneidensis MR-1 0.57 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.83 SO3471 glyA serine hydroxymethyltransferase (NCBI ptt file) 0.93 43
Shewanella sp. ANA-3 0.56 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.83 Shewana3_1094 glyA serine hydroxymethyltransferase (RefSeq) 0.91 36
Shewanella loihica PV-4 0.52 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.81 Shew_1185 glyA serine hydroxymethyltransferase (RefSeq) 0.89 41
Shewanella amazonensis SB2B 0.50 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.82 Sama_1014 glyA serine hydroxymethyltransferase (RefSeq) 0.90 49
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_0197 pyrroline-5-carboxylate reductase 0.72 B158DRAFT_1908 Glycine/serine hydroxymethyltransferase low > 40
Marinobacter adhaerens HP15 0.38 HP15_287 pyrroline-5-carboxylate reductase 0.74 HP15_489 glycine hydroxymethyltransferase — —
Acinetobacter radioresistens SK82 0.38 MPMX26_00572 Pyrroline-5-carboxylate reductase 0.71 MPMX26_02049 Serine hydroxymethyltransferase — —
Pseudomonas sp. BP01 0.37 JOY50_RS20905 proC pyrroline-5-carboxylate reductase 0.74 JOY50_RS24625 glyA serine hydroxymethyltransferase — —
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.74 PFLU_RS26195 serine hydroxymethyltransferase — —
Lysobacter sp. OAE881 0.37 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.71 ABIE51_RS04620 serine hydroxymethyltransferase low > 62
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.74 PFLU_RS26195 serine hydroxymethyltransferase — —
Paraburkholderia graminis OAS925 0.37 ABIE53_000840 pyrroline-5-carboxylate reductase 0.63 ABIE53_000888 glycine hydroxymethyltransferase — —
Pseudomonas putida KT2440 0.37 PP_5095 pyrroline-5-carboxylate reductase 0.74 PP_0671 serine hydroxymethyltransferase — —
Pseudomonas sp. SVBP6 0.36 COO64_RS12995 proC pyrroline-5-carboxylate reductase 0.74 COO64_RS02995 glyA serine hydroxymethyltransferase — —
Pseudomonas simiae WCS417 0.36 PS417_26730 pyrroline-5-carboxylate reductase 0.74 PS417_24280 serine hydroxymethyltransferase — —
Dechlorosoma suillum PS 0.36 Dsui_0602 pyrroline-5-carboxylate reductase 0.64 Dsui_1265 glycine/serine hydroxymethyltransferase — —
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.70 QEN71_RS33600 serine hydroxymethyltransferase low > 153
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.75 Psyr_4270 serine hydroxymethyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.75 Psyr_4270 serine hydroxymethyltransferase 0.83 11
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_13420 pyrroline-5-carboxylate reductase 0.74 AO356_15725 serine hydroxymethyltransferase — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08165 pyrroline-5-carboxylate reductase 0.74 AO353_14020 serine hydroxymethyltransferase — —
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.63 H281DRAFT_04726 serine hydroxymethyltransferase — —
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.74 PfGW456L13_1451 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.63 BPHYT_RS03725 serine hydroxymethyltransferase — —
Pseudomonas aeruginosa PA14 0.35 IKLFDK_23455 pyrroline-5-carboxylate reductase 0.73 IKLFDK_00500 Serine hydroxymethyltransferase 3 — —
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.75 Pf6N2E2_5082 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Pseudomonas sp. RS175 0.35 PFR28_04243 Pyrroline-5-carboxylate reductase 0.75 PFR28_03786 Serine hydroxymethyltransferase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS01230 pyrroline-5-carboxylate reductase 0.62 ABZR87_RS08955 serine hydroxymethyltransferase — —
Pseudomonas sp. S08-1 0.35 OH686_10980 pyrroline-5-carboxylate reductase 0.74 OH686_16230 Serine hydroxymethyltransferase — —
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.74 Pf1N1B4_2778 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Pseudomonas stutzeri RCH2 0.34 Psest_0283 pyrroline-5-carboxylate reductase 0.74 Psest_3404 Glycine/serine hydroxymethyltransferase — —
Pseudomonas sp. DMC3 0.34 GFF210 Pyrroline-5-carboxylate reductase 0.74 GFF3963 Serine hydroxymethyltransferase — —
Ralstonia solanacearum GMI1000 0.33 RS_RS13440 pyrroline-5-carboxylate reductase 0.62 RS_RS03670 serine hydroxymethyltransferase — —
Ralstonia solanacearum UW163 0.32 UW163_RS08045 pyrroline-5-carboxylate reductase 0.62 UW163_RS00670 serine hydroxymethyltransferase — —
Ralstonia solanacearum IBSBF1503 0.32 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.62 RALBFv3_RS12895 serine hydroxymethyltransferase — —
Dyella japonica UNC79MFTsu3.2 0.32 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.72 ABZR86_RS10715 serine hydroxymethyltransferase 0.89 28
Ralstonia solanacearum PSI07 0.32 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.62 RPSI07_RS20330 serine hydroxymethyltransferase 0.63 30
Variovorax sp. OAS795 0.32 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.62 ABID97_RS17890 serine hydroxymethyltransferase — —
Acidovorax sp. GW101-3H11 0.32 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.63 Ac3H11_2921 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Castellaniella sp019104865 MT123 0.32 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.69 ABCV34_RS06400 serine hydroxymethyltransferase low > 48
Methylophilus sp. DMC18 0.31 GFF863 Pyrroline-5-carboxylate reductase 0.64 GFF72 Serine hydroxymethyltransferase — —
Variovorax sp. SCN45 0.31 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.62 GFF560 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.71 Xcc-8004.4398.1 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.71 2
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS17360 pyrroline-5-carboxylate reductase 0.62 RR42_RS15485 serine hydroxymethyltransferase — —
Rhodanobacter sp000427505 FW510-R12 0.30 LRK53_RS05680 pyrroline-5-carboxylate reductase 0.72 LRK53_RS05390 serine hydroxymethyltransferase 0.64 45
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_11135 proC pyrroline-5-carboxylate reductase 0.72 OKGIIK_11440 glyA serine hydroxymethyltransferase low > 52
Rhodanobacter denitrificans MT42 0.29 LRK55_RS04030 pyrroline-5-carboxylate reductase 0.72 LRK55_RS04400 serine hydroxymethyltransferase — —
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS04260 pyrroline-5-carboxylate reductase 0.72 LRK54_RS04625 serine hydroxymethyltransferase 0.66 37
Herbaspirillum seropedicae SmR1 0.29 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.62 HSERO_RS06140 serine hydroxymethyltransferase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.62 GFF5152 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Enterobacter asburiae PDN3 0.27 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.79 EX28DRAFT_0099 Glycine/serine hydroxymethyltransferase — —
Escherichia fergusonii Becca 0.27 EFB2_03670 Pyrroline-5-carboxylate reductase 0.79 EFB2_01345 Serine hydroxymethyltransferase — —
Enterobacter sp. TBS_079 0.27 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.79 MPMX20_03420 Serine hydroxymethyltransferase — —
Klebsiella michiganensis M5al 0.27 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.79 BWI76_RS21225 serine hydroxymethyltransferase — —
Escherichia coli ECOR38 0.27 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.79 HEPCGN_20655 glyA serine hydroxymethyltransferase 0.77 65
Escherichia coli Nissle 1917 0.27 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.79 ECOLIN_RS14440 serine hydroxymethyltransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.27 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.79 OHPLBJKB_01156 Serine hydroxymethyltransferase low > 73
Escherichia coli ECOR27 0.27 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.79 NOLOHH_13185 glyA serine hydroxymethyltransferase 0.79 65
Escherichia coli BW25113 0.27 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.79 b2551 glyA serine hydroxymethyltransferase (NCBI) — —
Escherichia coli ECRC62 0.27 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.79 BNILDI_11985 glyA serine hydroxymethyltransferase low > 75
Escherichia coli BL21 0.27 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.79 ECD_02443 serine hydroxymethyltransferase 0.81 18
Escherichia coli ECRC102 0.27 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.79 NIAGMN_19280 glyA serine hydroxymethyltransferase — —
Escherichia coli ECRC98 0.27 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.79 JDDGAC_25175 glyA serine hydroxymethyltransferase — —
Escherichia coli ECRC100 0.27 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.79 OKFHMN_21510 glyA serine hydroxymethyltransferase 0.79 59
Escherichia coli ECRC101 0.27 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.79 MCAODC_12040 glyA serine hydroxymethyltransferase low > 87
Escherichia coli ECRC99 0.27 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.79 KEDOAH_06710 glyA serine hydroxymethyltransferase — —
Erwinia amylovora T8 0.26 OLJFJH_18285 pyrroline-5-carboxylate reductase 0.79 OLJFJH_10340 Serine hydroxymethyltransferase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.26 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.79 GFF2447 Serine hydroxymethyltransferase (EC 2.1.2.1) — —
Pantoea sp. MT58 0.26 IAI47_14945 pyrroline-5-carboxylate reductase 0.81 IAI47_04960 serine hydroxymethyltransferase — —
Synechocystis sp000284455 PCC 6803 0.25 SGL_RS17305 pyrroline-5-carboxylate reductase 0.57 SGL_RS04690 serine hydroxymethyltransferase — —
Desulfovibrio vulgaris Hildenborough JW710 0.24 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.56 DVU1203 glyA serine hydroxymethyltransferase (TIGR) — —
Erwinia tracheiphila SCR3 0.23 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.80 LU632_RS17915 serine hydroxymethyltransferase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.23 Echvi_2635 pyrroline-5-carboxylate reductase 0.51 Echvi_1188 Glycine/serine hydroxymethyltransferase 0.74 29
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.57 DvMF_3097 glyA serine hydroxymethyltransferase (RefSeq) — —
Bacteroides ovatus ATCC 8483 0.21 BACOVA_03587 pyrroline-5-carboxylate reductase 0.53 BACOVA_02446 glycine hydroxymethyltransferase 0.89 20
Bacteroides thetaiotaomicron VPI-5482 0.19 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.53 BT0738 serine hydroxymethyltransferase (NCBI ptt file) 0.84 36
Pontibacter actiniarum KMM 6156, DSM 19842 0.16 CA264_07730 pyrroline-5-carboxylate reductase 0.50 CA264_17045 serine hydroxymethyltransferase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.15 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.50 CA265_RS19165 serine hydroxymethyltransferase 0.90 39
Phocaeicola vulgatus CL09T03C04 0.15 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.54 HMPREF1058_RS03800 serine hydroxymethyltransferase 0.82 36
Phocaeicola dorei CL03T12C01 0.15 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.54 ABI39_RS17420 serine hydroxymethyltransferase 0.79 31
Parabacteroides merdae CL09T00C40 0.15 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase 0.53 HMPREF1078_RS02145 serine hydroxymethyltransferase low > 61
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.53 HMPREF1181_RS15010 serine hydroxymethyltransferase low > 56
Cellulophaga baltica 18 0.14 M666_RS02635 pyrroline-5-carboxylate reductase 0.54 M666_RS14985 serine hydroxymethyltransferase low > 67

Not shown: 20 genomes with orthologs for CSW01_02450 only; 0 genomes with orthologs for CSW01_04820 only