Conservation of cofitness between BWI76_RS27390 and BWI76_RS09910 in Klebsiella michiganensis M5al

87 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS27390 ribonuclease PH 1.0 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.85 2
Enterobacter sp. TBS_079 0.94 MPMX20_00092 Ribonuclease PH 0.92 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) low > 85
Enterobacter asburiae PDN3 0.93 EX28DRAFT_3893 ribonuclease PH 0.92 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF366 Ribonuclease PH (EC 2.7.7.56) 0.93 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 78
Escherichia coli ECRC62 0.92 BNILDI_04045 rph ribonuclease PH 0.93 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_00059 Ribonuclease PH 0.93 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) low > 73
Escherichia coli BL21 0.92 ECD_03500 ribonuclease PH 0.93 ECD_00949 dihydro-orotate oxidase, FMN-linked low > 61
Escherichia coli Nissle 1917 0.92 ECOLIN_RS20755 ribonuclease PH 0.93 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC101 0.92 MCAODC_06100 rph ribonuclease PH 0.93 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.62 31
Escherichia coli ECRC100 0.92 OKFHMN_15590 rph ribonuclease PH 0.93 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 0.82 16
Escherichia coli ECRC102 0.92 NIAGMN_13350 rph ribonuclease PH 0.93 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia fergusonii Becca 0.92 EFB2_00170 Ribonuclease PH 0.93 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Escherichia coli ECOR38 0.92 HEPCGN_14410 rph ribonuclease PH 0.93 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase low > 87
Escherichia coli ECOR27 0.92 NOLOHH_07470 rph ribonuclease PH 0.93 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 0.77 14
Escherichia coli ECRC99 0.92 KEDOAH_12555 rph ribonuclease PH 0.93 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC98 0.92 JDDGAC_19215 rph ribonuclease PH 0.93 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase low > 86
Dickeya dadantii 3937 0.89 DDA3937_RS20540 ribonuclease PH 0.85 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase low > 74
Dickeya dianthicola 67-19 0.89 HGI48_RS00675 ribonuclease PH 0.85 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase low > 71
Dickeya dianthicola ME23 0.89 DZA65_RS00730 ribonuclease PH 0.85 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase low > 75
Pantoea sp. MT58 0.89 IAI47_00595 ribonuclease PH 0.82 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.67 7
Erwinia tracheiphila SCR3 0.88 LU632_RS22020 rph ribonuclease PH 0.83 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase low > 74
Escherichia coli BW25113 0.87 b3643 rph ribonuclease PH (NCBI) 0.93 b0945 pyrD dihydroorotate dehydrogenase (NCBI) low > 76
Serratia liquefaciens MT49 0.87 IAI46_24850 ribonuclease PH 0.86 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.46 9
Rahnella sp. WP5 0.87 EX31_RS14505 ribonuclease PH 0.87 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.74 12
Pectobacterium carotovorum WPP14 0.86 HER17_RS20855 ribonuclease PH 0.86 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase low > 75
Shewanella amazonensis SB2B 0.78 Sama_0320 tRNA nucleotidyltransferase (RefSeq) 0.63 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) low > 62
Shewanella loihica PV-4 0.78 Shew_3488 ribonuclease PH (RefSeq) 0.63 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) low > 60
Shewanella oneidensis MR-1 0.77 SO4256 rph ribonuclease PH (NCBI ptt file) 0.64 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) low > 76
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_01115 ribonuclease PH 0.71 CSW01_07490 dihydroorotate dehydrogenase (quinone) low > 62
Shewanella sp. ANA-3 0.77 Shewana3_3777 RNAse PH (RefSeq) 0.65 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) low > 73
Alteromonas macleodii MIT1002 0.75 MIT1002_04071 Ribonuclease PH 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) low > 70
Marinobacter adhaerens HP15 0.70 HP15_300 ribonuclease PH 0.48 HP15_1377 dihydroorotate dehydrogenase low > 73
Pseudomonas sp. S08-1 0.70 OH686_13570 ribonuclease PH 0.56 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Kangiella aquimarina DSM 16071 0.70 B158DRAFT_0588 ribonuclease PH 0.56 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) — —
Pseudomonas stutzeri RCH2 0.69 Psest_3813 ribonuclease PH 0.55 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 low > 67
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_0213 RNAse PH 0.57 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_0213 RNAse PH 0.57 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas fluorescens FW300-N1B4 0.68 Pf1N1B4_2117 Ribonuclease PH (EC 2.7.7.56) 0.58 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2E2 0.68 Pf6N2E2_4365 Ribonuclease PH (EC 2.7.7.56) 0.57 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas putida KT2440 0.68 PP_5294 Ribonuclease PH 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens FW300-N2C3 0.68 AO356_12500 ribonuclease PH 0.57 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Dechlorosoma suillum PS 0.68 Dsui_0494 ribonuclease PH 0.57 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Pseudomonas fluorescens GW456-L13 0.68 PfGW456L13_784 Ribonuclease PH (EC 2.7.7.56) 0.56 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2E3 0.68 AO353_09260 ribonuclease PH 0.57 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas sp. RS175 0.68 PFR28_04420 Ribonuclease PH 0.57 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas simiae WCS417 0.68 PS417_27810 ribonuclease PH 0.57 PS417_20935 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.68 PFLU_RS29490 ribonuclease PH 0.58 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.68 PFLU_RS29490 ribonuclease PH 0.58 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.67 Xcc-8004.1221.1 Ribonuclease PH (EC 2.7.7.56) 0.46 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Acinetobacter radioresistens SK82 0.67 MPMX26_00040 Ribonuclease PH 0.54 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) low > 36
Variovorax sp. SCN45 0.67 GFF2381 Ribonuclease PH (EC 2.7.7.56) 0.50 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.66 GFF3254 Ribonuclease PH (EC 2.7.7.56) 0.49 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 90
Paraburkholderia sabiae LMG 24235 0.65 QEN71_RS03645 ribonuclease PH 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.65 H281DRAFT_04008 RNAse PH 0.55 H281DRAFT_00743 dihydroorotate oxidase A — —
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS15255 ribonuclease PH 0.55 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Burkholderia phytofirmans PsJN 0.65 BPHYT_RS15325 ribonuclease PH 0.57 BPHYT_RS08565 dihydroorotate dehydrogenase low > 109
Paraburkholderia graminis OAS925 0.65 ABIE53_003234 ribonuclease PH 0.57 ABIE53_001954 dihydroorotate dehydrogenase — —
Variovorax sp. OAS795 0.64 ABID97_RS23640 ribonuclease PH 0.50 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.64 RPSI07_RS13840 ribonuclease PH 0.54 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.64 RS_RS10830 ribonuclease PH 0.54 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Herbaspirillum seropedicae SmR1 0.64 HSERO_RS10655 ribonuclease PH 0.54 HSERO_RS16155 dihydroorotate dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.64 ABZR86_RS11900 ribonuclease PH 0.49 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum UW163 0.63 UW163_RS10375 ribonuclease PH 0.55 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS03345 ribonuclease PH 0.55 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.63 RR42_RS04890 ribonuclease PH 0.53 RR42_RS07465 dihydroorotate dehydrogenase — —
Lysobacter sp. OAE881 0.62 ABIE51_RS17285 ribonuclease PH 0.45 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase — —
Azospirillum brasilense Sp245 0.62 AZOBR_RS02205 ribonuclease PH 0.38 AZOBR_RS13520 dihydroorotate dehydrogenase low > 97
Acidovorax sp. GW101-3H11 0.61 Ac3H11_3670 Ribonuclease PH (EC 2.7.7.56) 0.52 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Castellaniella sp019104865 MT123 0.61 ABCV34_RS03515 ribonuclease PH 0.52 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.60 LRK55_RS11470 ribonuclease PH 0.49 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Agrobacterium fabrum C58 0.60 Atu0327 ribonuclease PH 0.41 Atu0486 dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.60 LRK54_RS11745 ribonuclease PH 0.49 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.60 TX73_001710 ribonuclease PH 0.38 TX73_004110 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.59 OKGIIK_12150 rph ribonuclease PH 0.47 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Bosea sp. OAE506 0.59 ABIE41_RS03295 ribonuclease PH 0.33 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase low > 77
Sinorhizobium meliloti 1021 0.59 SMc01144 ribonuclease PH 0.40 SMc02245 dihydroorotate dehydrogenase 2 low > 103
Azospirillum sp. SherDot2 0.59 MPMX19_02576 Ribonuclease PH 0.38 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Rhizobium sp. OAE497 0.59 ABIE40_RS01640 ribonuclease PH 0.39 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Dinoroseobacter shibae DFL-12 0.58 Dshi_3463 ribonuclease PH (RefSeq) 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) low > 64
Magnetospirillum magneticum AMB-1 0.58 AMB_RS22760 ribonuclease PH 0.35 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Rhodospirillum rubrum S1H 0.58 Rru_A3641 Ribonuclease PH (NCBI) 0.37 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) low > 58
Phaeobacter inhibens DSM 17395 0.57 PGA1_c35030 ribonuclease PH 0.34 PGA1_c12150 dihydroorotate dehydrogenase PyrD low > 62
Brevundimonas sp. GW460-12-10-14-LB2 0.55 A4249_RS13125 ribonuclease PH 0.37 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase — —
Caulobacter crescentus NA1000 0.55 CCNA_00151 ribonuclease PH 0.31 CCNA_00562 dihydroorotate dehydrogenase low > 66
Caulobacter crescentus NA1000 Δfur 0.55 CCNA_00151 ribonuclease PH 0.31 CCNA_00562 dihydroorotate dehydrogenase low > 67
Mycobacterium tuberculosis H37Rv 0.55 Rv1340 Probable ribonuclease RphA (RNase PH) (tRNA nucleotidyltransferase) 0.36 Rv2139 Probable dihydroorotate dehydrogenase PyrD — —
Sphingomonas koreensis DSMZ 15582 0.54 Ga0059261_2741 ribonuclease PH 0.39 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) — —
Bifidobacterium breve UCC2003 0.52 BBR_RS12405 ribonuclease PH 0.22 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase low > 34

Not shown: 1 genomes with orthologs for BWI76_RS27390 only; 7 genomes with orthologs for BWI76_RS09910 only