Conservation of cofitness between BPHYT_RS13220 and BPHYT_RS33900 in Burkholderia phytofirmans PsJN

92 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS13220 phosphomethylpyrimidine synthase 1.0 BPHYT_RS33900 3-isopropylmalate dehydrogenase 0.73 2
Paraburkholderia graminis OAS925 0.99 ABIE53_002857 phosphomethylpyrimidine synthase 0.98 ABIE53_004804 3-isopropylmalate dehydrogenase 0.77 1
Paraburkholderia bryophila 376MFSha3.1 0.98 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.98 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.44 49
Paraburkholderia sabiae LMG 24235 0.95 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.96 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.60 144
Herbaspirillum seropedicae SmR1 0.85 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.86 HSERO_RS16500 3-isopropylmalate dehydrogenase 0.36 41
Dechlorosoma suillum PS 0.85 Dsui_0422 thiamine biosynthesis protein ThiC 0.68 Dsui_3198 3-isopropylmalate dehydrogenase — —
Castellaniella sp019104865 MT123 0.78 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.75 ABCV34_RS04280 3-isopropylmalate dehydrogenase low > 48
Dyella japonica UNC79MFTsu3.2 0.75 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.40 ABZR86_RS15950 3-isopropylmalate dehydrogenase low > 74
Marinobacter adhaerens HP15 0.75 HP15_453 thiamine biosynthesis protein thiC 0.64 HP15_1832 3-isopropylmalate dehydrogenase low > 73
Pseudomonas putida KT2440 0.75 PP_4922 Phosphomethylpyrimidine synthase 0.64 PP_1988 3-isopropylmalate dehydrogenase 0.38 51
Pseudomonas sp. S08-1 0.74 OH686_15885 phosphomethylpyrimidine synthase 0.62 OH686_04470 3-isopropylmalate dehydrogenase low > 80
Rhodanobacter sp. FW510-T8 0.74 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.42 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase low > 52
Pseudomonas stutzeri RCH2 0.74 Psest_0477 thiamine biosynthesis protein ThiC 0.63 Psest_2589 3-isopropylmalate dehydrogenase low > 67
Pseudomonas fluorescens FW300-N2E2 0.74 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.64 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 103
Xanthomonas campestris pv. campestris strain 8004 0.74 Xcc-8004.1066.1 hypothetical protein 0.60 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.60 49
Pseudomonas fluorescens FW300-N2E3 0.74 AO353_13010 thiamine biosynthesis protein ThiC 0.65 AO353_20635 3-isopropylmalate dehydrogenase low > 101
Pseudomonas fluorescens FW300-N2C3 0.74 AO356_08810 thiamine biosynthesis protein ThiC 0.64 AO356_21415 3-isopropylmalate dehydrogenase low > 104
Pseudomonas sp. RS175 0.74 PFR28_05091 Phosphomethylpyrimidine synthase 0.64 PFR28_02821 3-isopropylmalate dehydrogenase low > 88
Pseudomonas fluorescens FW300-N1B4 0.73 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.65 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 87
Pseudomonas fluorescens SBW25 0.73 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.63 PFLU_RS20565 3-isopropylmalate dehydrogenase low > 109
Pseudomonas fluorescens GW456-L13 0.73 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.64 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 87
Pseudomonas fluorescens SBW25-INTG 0.73 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.63 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.35 41
Pseudomonas syringae pv. syringae B728a ΔmexB 0.73 Psyr_0544 hydroxymethylpyrimidine synthase 0.63 Psyr_1985 3-isopropylmalate dehydrogenase 0.50 15
Pseudomonas syringae pv. syringae B728a 0.73 Psyr_0544 hydroxymethylpyrimidine synthase 0.63 Psyr_1985 3-isopropylmalate dehydrogenase 0.55 43
Pseudomonas simiae WCS417 0.73 PS417_02355 thiamine biosynthesis protein ThiC 0.64 PS417_18585 3-isopropylmalate dehydrogenase low > 88
Lysobacter sp. OAE881 0.73 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.44 ABIE51_RS17585 3-isopropylmalate dehydrogenase low > 62
Mucilaginibacter yixingensis YX-36 DSM 26809 0.72 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.47 ABZR88_RS11605 3-isopropylmalate dehydrogenase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.72 CA264_20435 phosphomethylpyrimidine synthase ThiC 0.43 CA264_09445 3-isopropylmalate dehydrogenase low > 74
Acinetobacter radioresistens SK82 0.71 MPMX26_00180 Phosphomethylpyrimidine synthase 0.59 MPMX26_00348 3-isopropylmalate dehydrogenase low > 36
Pedobacter sp. GW460-11-11-14-LB5 0.71 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.48 CA265_RS15850 3-isopropylmalate dehydrogenase low > 88
Echinicola vietnamensis KMM 6221, DSM 17526 0.71 Echvi_3567 thiamine biosynthesis protein ThiC 0.44 Echvi_2062 3-isopropylmalate dehydrogenase — —
Ralstonia solanacearum PSI07 0.69 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.89 RPSI07_RS14705 3-isopropylmalate dehydrogenase low > 81
Pectobacterium carotovorum WPP14 0.69 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.49 HER17_RS03080 3-isopropylmalate dehydrogenase low > 75
Shewanella loihica PV-4 0.69 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.48 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) low > 60
Ralstonia sp. UNC404CL21Col 0.68 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.89 ABZR87_RS14530 3-isopropylmalate dehydrogenase 0.58 31
Cupriavidus basilensis FW507-4G11 0.68 RR42_RS01290 thiamine biosynthesis protein ThiC 0.89 RR42_RS14385 3-isopropylmalate dehydrogenase 0.77 21
Ralstonia solanacearum UW163 0.68 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.89 UW163_RS11115 3-isopropylmalate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.68 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.89 RALBFv3_RS02610 3-isopropylmalate dehydrogenase low > 76
Shewanella amazonensis SB2B 0.68 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.47 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) low > 62
Rahnella sp. WP5 0.68 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.50 EX31_RS03685 3-isopropylmalate dehydrogenase low > 89
Ralstonia solanacearum GMI1000 0.68 RS_RS00555 phosphomethylpyrimidine synthase 0.89 RS_RS09990 3-isopropylmalate dehydrogenase low > 80
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.68 GFF4198 Thiamin biosynthesis protein ThiC 0.50 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 78
Enterobacter sp. TBS_079 0.68 MPMX20_00217 Phosphomethylpyrimidine synthase 0.49 MPMX20_00768 3-isopropylmalate dehydrogenase low > 85
Serratia liquefaciens MT49 0.67 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.51 IAI46_03350 3-isopropylmalate dehydrogenase low > 86
Enterobacter asburiae PDN3 0.67 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.49 EX28DRAFT_3669 3-isopropylmalate dehydrogenase low > 76
Escherichia coli Nissle 1917 0.67 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.49 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.60 29
Escherichia fergusonii Becca 0.67 EFB2_04617 Phosphomethylpyrimidine synthase 0.49 EFB2_03972 3-isopropylmalate dehydrogenase low > 86
Kangiella aquimarina DSM 16071 0.67 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.63 B158DRAFT_1322 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 40
Escherichia coli ECOR27 0.67 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.49 NOLOHH_03065 leuA 2-isopropylmalate synthase low > 75
Escherichia coli ECRC62 0.67 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.49 BNILDI_08545 leuA 2-isopropylmalate synthase low > 75
Escherichia coli ECRC101 0.67 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.49 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase low > 87
Escherichia coli ECRC98 0.67 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.49 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase low > 86
Escherichia coli ECRC102 0.67 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.49 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.67 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.49 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 73
Escherichia coli ECRC100 0.67 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.49 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase low > 80
Escherichia coli BW25113 0.67 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.49 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) low > 76
Escherichia coli ECRC99 0.67 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.49 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli BL21 0.67 ECD_03871 phosphomethylpyrimidine synthase 0.49 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.52 42
Escherichia coli ECOR38 0.67 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.49 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase low > 87
Dickeya dadantii 3937 0.67 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.49 DDA3937_RS18120 3-isopropylmalate dehydrogenase low > 74
Klebsiella michiganensis M5al 0.67 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.50 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.33 92
Pantoea sp. MT58 0.67 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.47 IAI47_16005 3-isopropylmalate dehydrogenase low > 76
Erwinia tracheiphila SCR3 0.67 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.47 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase low > 74
Variovorax sp. SCN45 0.67 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.79 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 127
Shewanella oneidensis MR-1 0.67 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.48 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) low > 76
Vibrio cholerae E7946 ATCC 55056 0.66 CSW01_00335 phosphomethylpyrimidine synthase 0.49 CSW01_12600 3-isopropylmalate dehydrogenase low > 62
Alteromonas macleodii MIT1002 0.66 MIT1002_00097 Phosphomethylpyrimidine synthase 0.51 MIT1002_00948 3-isopropylmalate dehydrogenase low > 70
Shewanella sp. ANA-3 0.66 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.48 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) low > 73
Dickeya dianthicola ME23 0.66 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.50 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.66 57
Dickeya dianthicola 67-19 0.66 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.49 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.79 41
Hydrogenophaga sp. GW460-11-11-14-LB1 0.66 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.77 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 90
Acidovorax sp. GW101-3H11 0.65 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.79 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.91 16
Variovorax sp. OAS795 0.65 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.79 ABID97_RS08455 3-isopropylmalate dehydrogenase — —
Azospirillum brasilense Sp245 0.64 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.49 AZOBR_RS14130 3-isopropylmalate dehydrogenase 0.43 45
Magnetospirillum magneticum AMB-1 0.63 AMB_RS01125 phosphomethylpyrimidine synthase 0.52 AMB_RS20570 3-isopropylmalate dehydrogenase — —
Phaeobacter inhibens DSM 17395 0.62 PGA1_c09110 thiamine biosynthesis protein ThiC 0.54 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB low > 62
Sinorhizobium meliloti 1021 0.62 SM_b20615 thiamine biosynthesis protein ThiC 0.50 SMc04405 3-isopropylmalate dehydrogenase low > 103
Sphingomonas koreensis DSMZ 15582 0.62 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.60 Ga0059261_3190 3-isopropylmalate dehydrogenase 0.90 41
Dinoroseobacter shibae DFL-12 0.62 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.52 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) — —
Agrobacterium fabrum C58 0.62 Atu2569 thiamine biosynthesis protein 0.49 Atu2791 3-isopropylmalate dehydrogenase 0.71 32
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_02109 thiamine biosynthesis protein thiC 0.48 CCNA_00193 3-isopropylmalate dehydrogenase low > 67
Caulobacter crescentus NA1000 0.61 CCNA_02109 thiamine biosynthesis protein thiC 0.48 CCNA_00193 3-isopropylmalate dehydrogenase low > 66
Brevundimonas sp. GW460-12-10-14-LB2 0.60 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.42 A4249_RS09995 3-isopropylmalate dehydrogenase low > 48
Bosea sp. OAE506 0.60 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.51 ABIE41_RS11860 3-isopropylmalate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.60 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.48 TX73_001175 3-isopropylmalate dehydrogenase — —
Azospirillum sp. SherDot2 0.60 MPMX19_00336 Phosphomethylpyrimidine synthase 0.51 MPMX19_00607 3-isopropylmalate dehydrogenase low > 112
Rhodospirillum rubrum S1H 0.57 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.51 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) low > 58
Phocaeicola dorei CL03T12C01 0.56 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.39 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.57 38
Bacteroides stercoris CC31F 0.56 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.39 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase low > 56
Phocaeicola vulgatus CL09T03C04 0.56 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.39 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.65 64
Bacteroides ovatus ATCC 8483 0.56 BACOVA_02358 thiamine biosynthesis protein ThiC 0.39 BACOVA_04600 3-isopropylmalate dehydrogenase 0.79 17
Bacteroides thetaiotaomicron VPI-5482 0.56 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.39 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.40 57
Parabacteroides merdae CL09T00C40 0.56 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC 0.40 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase low > 61

Not shown: 1 genomes with orthologs for BPHYT_RS13220 only; 7 genomes with orthologs for BPHYT_RS33900 only