Conservation of cofitness between BBR_RS15810 and BBR_RS10595 in Bifidobacterium breve UCC2003

86 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bifidobacterium breve UCC2003 1.0 BBR_RS15810 tryptophan synthase subunit alpha 1.0 BBR_RS10595 glutamine amidotransferase 0.71 3
Mycobacterium tuberculosis H37Rv 0.40 Rv1613 Probable tryptophan synthase, alpha subunit TrpA 0.45 Rv0013 Possible anthranilate synthase component II TrpG (glutamine amidotransferase)
Methanococcus maripaludis S2 0.27 MMP_RS05185 tryptophan synthase subunit alpha 0.30 MMP_RS05200 aminodeoxychorismate/anthranilate synthase component II
Pseudomonas stutzeri RCH2 0.27 Psest_0062 tryptophan synthase, alpha subunit 0.40 Psest_3649 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 0.73 8
Methanococcus maripaludis JJ 0.26 MMJJ_RS09195 tryptophan synthase subunit alpha 0.31 MMJJ_RS09180 aminodeoxychorismate/anthranilate synthase component II
Synechococcus elongatus PCC 7942 0.26 Synpcc7942_0411 trpA tryptophan synthase subunit alpha 0.39 Synpcc7942_0400 trpG anthranilate synthase, component II
Pseudomonas sp. S08-1 0.26 OH686_12430 tryptophan synthase, alpha subunit 0.38 OH686_15130 Anthranilate synthase, amidotransferase component or Para-aminobenzoate synthase, amidotransferase component
Marinobacter adhaerens HP15 0.26 HP15_1826 tryptophan synthase, alpha subunit 0.40 HP15_3289 para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II
Phaeobacter inhibens DSM 17395 0.26 PGA1_c04930 tryptophan synthase alpha chain 0.36 PGA1_c16880 anthranilate synthase component II
Magnetospirillum magneticum AMB-1 0.26 AMB_RS20300 tryptophan synthase subunit alpha 0.37 AMB_RS14405 type 1 glutamine amidotransferase
Pseudomonas fluorescens SBW25 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.39 PFLU_RS27375 aminodeoxychorismate/anthranilate synthase component II low > 109
Pseudomonas simiae WCS417 0.25 PS417_00180 tryptophan synthase subunit alpha 0.39 PS417_25720 anthranilate synthase component II 0.72 6
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.39 PFLU_RS27375 aminodeoxychorismate/anthranilate synthase component II low > 109
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_10705 tryptophan synthase subunit alpha 0.39 AO353_07220 anthranilate synthase 0.81 16
Pseudomonas sp. RS175 0.25 PFR28_04716 Tryptophan synthase alpha chain 0.39 PFR28_04045 Anthranilate synthase component 2
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_10910 tryptophan synthase subunit alpha 0.39 AO356_14430 anthranilate synthase 0.88 32
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_565 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.39 PfGW456L13_1220 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.91 6
Dinoroseobacter shibae DFL-12 0.25 Dshi_0952 tryptophan synthase, alpha subunit (RefSeq) 0.37 Dshi_1798 glutamine amidotransferase of anthranilate synthase (RefSeq)
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_1830 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.39 Pf1N1B4_2547 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.83 22
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4047 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.39 Pf6N2E2_4824 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.55 52
Mucilaginibacter yixingensis YX-36 DSM 26809 0.25 ABZR88_RS10660 tryptophan synthase subunit alpha 0.32 ABZR88_RS16600 aminodeoxychorismate/anthranilate synthase component II
Acinetobacter radioresistens SK82 0.25 MPMX26_02611 Tryptophan synthase alpha chain 0.34 MPMX26_00985 Anthranilate synthase component 2
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.39 Psyr_4581 anthranilate synthase, component II 0.50 49
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.39 Psyr_4581 anthranilate synthase, component II
Pseudomonas putida KT2440 0.24 PP_0082 tryptophan synthase alpha chain 0.38 PP_0420 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex 0.79 29
Acidovorax sp. GW101-3H11 0.24 Ac3H11_1535 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.38 Ac3H11_769 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.93 11
Parabacteroides merdae CL09T00C40 0.23 HMPREF1078_RS00120 tryptophan synthase subunit alpha 0.30 HMPREF1078_RS00140 aminodeoxychorismate/anthranilate synthase component II low > 61
Variovorax sp. SCN45 0.23 GFF3882 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.35 GFF5894 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85)
Dechlorosoma suillum PS 0.23 Dsui_3191 tryptophan synthase, alpha subunit 0.41 Dsui_0170 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase
Phocaeicola dorei CL03T12C01 0.23 ABI39_RS21075 tryptophan synthase subunit alpha 0.30 ABI39_RS21055 aminodeoxychorismate/anthranilate synthase component II low > 72
Phocaeicola vulgatus CL09T03C04 0.23 HMPREF1058_RS07200 tryptophan synthase subunit alpha 0.30 HMPREF1058_RS07180 aminodeoxychorismate/anthranilate synthase component II 0.87 23
Bosea sp. OAE506 0.23 ABIE41_RS03930 tryptophan synthase subunit alpha 0.36 ABIE41_RS17415 aminodeoxychorismate/anthranilate synthase component II
Shewanella oneidensis MR-1 0.23 SO3024 trpA tryptophan synthase, alpha subunit (NCBI ptt file) 0.36 SO0613 pabA para-aminobenzoate synthase glutamine amidotransferase, component II (NCBI ptt file) low > 76
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS15350 tryptophan synthase subunit alpha 0.33 HMPREF1181_RS15330 aminodeoxychorismate/anthranilate synthase component II 0.94 6
Serratia liquefaciens MT49 0.22 IAI46_14045 tryptophan synthase subunit alpha 0.38 IAI46_23595 aminodeoxychorismate synthase component II 0.72 15
Bacteroides thetaiotaomicron VPI-5482 0.22 BT0527 tryptophan synthase alpha chain (NCBI ptt file) 0.30 BT0531 anthranilate synthase component II (NCBI ptt file) 0.63 63
Shewanella sp. ANA-3 0.22 Shewana3_1515 trpA tryptophan synthase subunit alpha (RefSeq) 0.35 Shewana3_0606 aminodeoxychorismate synthase, glutamine amidotransferase subunit (RefSeq) low > 73
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS14350 tryptophan synthase alpha chain 0.37 RR42_RS18300 anthranilate synthase subunit II
Bacteroides ovatus ATCC 8483 0.22 BACOVA_03785 tryptophan synthase, alpha subunit 0.32 BACOVA_03781 glutamine amidotransferase, class I 0.85 53
Vibrio cholerae E7946 ATCC 55056 0.22 CSW01_05925 tryptophan synthase subunit alpha 0.38 CSW01_13255 aminodeoxychorismate/anthranilate synthase component II low > 62
Azospirillum brasilense Sp245 0.22 AZOBR_RS00520 tryptophan synthase subunit alpha 0.34 AZOBR_RS07460 anthranilate synthase
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS14490 tryptophan synthase subunit alpha 0.36 ABZR87_RS02145 aminodeoxychorismate/anthranilate synthase component II 0.84 20
Variovorax sp. OAS795 0.22 ABID97_RS08425 tryptophan synthase subunit alpha 0.36 ABID97_RS05260 aminodeoxychorismate/anthranilate synthase component II 0.73 6
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_03657 tryptophan synthase alpha chain 0.40 CCNA_01974 anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II low > 67
Caulobacter crescentus NA1000 0.22 CCNA_03657 tryptophan synthase alpha chain 0.40 CCNA_01974 anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II 0.92 7
Ralstonia solanacearum GMI1000 0.21 RS_RS09955 tryptophan synthase subunit alpha 0.37 RS_RS14435 type 1 glutamine amidotransferase
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS11320 tryptophan synthase subunit alpha 0.40 A4249_RS06165 aminodeoxychorismate/anthranilate synthase component II
Ralstonia solanacearum PSI07 0.21 RPSI07_RS14740 tryptophan synthase subunit alpha 0.36 RPSI07_RS10750 type 1 glutamine amidotransferase
Pantoea sp. MT58 0.21 IAI47_09165 tryptophan synthase subunit alpha 0.38 IAI47_01950 aminodeoxychorismate/anthranilate synthase component II low > 76
Azospirillum sp. SherDot2 0.21 MPMX19_02737 Tryptophan synthase alpha chain 0.34 MPMX19_01016 Anthranilate synthase component 2
Ralstonia solanacearum UW163 0.21 UW163_RS11150 tryptophan synthase subunit alpha 0.35 UW163_RS07135 type 1 glutamine amidotransferase
Ralstonia solanacearum IBSBF1503 0.21 RALBFv3_RS02575 tryptophan synthase subunit alpha 0.35 RALBFv3_RS06490 type 1 glutamine amidotransferase
Alteromonas macleodii MIT1002 0.21 MIT1002_01425 Tryptophan synthase alpha chain 0.32 MIT1002_00439 Para-aminobenzoate synthase glutamine amidotransferase component II
Klebsiella michiganensis M5al 0.21 BWI76_RS11840 tryptophan synthase subunit alpha 0.36 BWI76_RS26005 glutamine amidotransferase low > 92
Herbaspirillum seropedicae SmR1 0.21 HSERO_RS16470 tryptophan synthase subunit alpha 0.36 HSERO_RS19440 anthranilate synthase subunit II
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_1740 trpA tryptophan synthase subunit alpha (RefSeq) 0.33 DvMF_1745 glutamine amidotransferase of anthranilate synthase (RefSeq) 0.76 42
Paraburkholderia graminis OAS925 0.21 ABIE53_004811 tryptophan synthase alpha chain 0.35 ABIE53_003641 anthranilate synthase component 2
Dickeya dianthicola 67-19 0.20 HGI48_RS10460 tryptophan synthase subunit alpha 0.40 HGI48_RS19575 aminodeoxychorismate synthase component II
Dickeya dianthicola ME23 0.20 DZA65_RS10940 tryptophan synthase subunit alpha 0.40 DZA65_RS20660 aminodeoxychorismate synthase component II low > 75
Dickeya dadantii 3937 0.20 DDA3937_RS10460 tryptophan synthase subunit alpha 0.39 DDA3937_RS19455 aminodeoxychorismate synthase component II
Xanthomonas campestris pv. campestris strain 8004 0.20 Xcc-8004.1967.1 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.38 Xcc-8004.618.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.90 8
Shewanella loihica PV-4 0.20 Shew_2256 trpA tryptophan synthase subunit alpha (RefSeq) 0.34 Shew_0575 glutamine amidotransferase of anthranilate synthase (RefSeq) low > 60
Rahnella sp. WP5 0.20 EX31_RS09980 tryptophan synthase subunit alpha 0.37 EX31_RS04635 aminodeoxychorismate synthase component II low > 89
Enterobacter asburiae PDN3 0.20 EX28DRAFT_0932 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.39 EX28DRAFT_4169 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase low > 76
Enterobacter sp. TBS_079 0.20 MPMX20_02514 Tryptophan synthase alpha chain 0.38 MPMX20_04263 Aminodeoxychorismate synthase component 2 low > 85
Escherichia fergusonii Becca 0.20 EFB2_02666 Tryptophan synthase alpha chain 0.39 EFB2_00462 Aminodeoxychorismate synthase component 2 low > 86
Escherichia coli ECOR38 0.19 HEPCGN_25515 trpA tryptophan synthase subunit alpha 0.40 HEPCGN_16050 pabA aminodeoxychorismate synthase component 2 low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.19 OHPLBJKB_02423 Tryptophan synthase alpha chain 0.39 OHPLBJKB_00342 Aminodeoxychorismate synthase component 2 low > 73
Escherichia coli BW25113 0.19 b1260 trpA tryptophan synthase subunit alpha (NCBI) 0.39 b3360 pabA para-aminobenzoate synthase component II (NCBI) low > 76
Escherichia coli BL21 0.19 ECD_01234 tryptophan synthase, alpha subunit 0.39 ECD_03211 aminodeoxychorismate synthase, subunit II low > 61
Escherichia coli Nissle 1917 0.19 ECOLIN_RS07595 tryptophan synthase subunit alpha 0.39 ECOLIN_RS19245 aminodeoxychorismate synthase component 2
Escherichia coli ECOR27 0.19 NOLOHH_20335 trpA tryptophan synthase subunit alpha 0.39 NOLOHH_09020 pabA aminodeoxychorismate synthase component 2 low > 75
Escherichia coli ECRC62 0.19 BNILDI_18480 trpA tryptophan synthase subunit alpha 0.39 BNILDI_02500 pabA aminodeoxychorismate synthase component 2 low > 75
Erwinia tracheiphila SCR3 0.19 LU632_RS12775 trpA tryptophan synthase subunit alpha 0.35 LU632_RS22815 aminodeoxychorismate synthase component II
Pectobacterium carotovorum WPP14 0.19 HER17_RS10940 tryptophan synthase subunit alpha 0.38 HER17_RS01905 aminodeoxychorismate synthase component II low > 75
Escherichia coli ECRC101 0.19 MCAODC_15590 trpA tryptophan synthase subunit alpha 0.39 MCAODC_07750 pabA aminodeoxychorismate synthase component 2 low > 87
Escherichia coli ECRC99 0.19 KEDOAH_26075 trpA tryptophan synthase subunit alpha 0.39 KEDOAH_10920 pabA aminodeoxychorismate synthase component 2
Escherichia coli ECRC102 0.19 NIAGMN_26845 trpA tryptophan synthase subunit alpha 0.39 NIAGMN_14990 pabA aminodeoxychorismate synthase component 2
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.19 GFF2726 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.38 GFF3709 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) low > 78
Escherichia coli ECRC98 0.19 JDDGAC_05220 trpA tryptophan synthase subunit alpha 0.39 JDDGAC_20850 pabA aminodeoxychorismate synthase component 2 low > 86
Escherichia coli ECRC100 0.19 OKFHMN_02675 trpA tryptophan synthase subunit alpha 0.39 OKFHMN_17220 pabA aminodeoxychorismate synthase component 2 low > 80
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_06065 tryptophan synthase, alpha chain 0.35 H281DRAFT_05714 anthranilate synthase, component II 0.45 26
Castellaniella sp019104865 MT123 0.19 ABCV34_RS08430 tryptophan synthase subunit alpha 0.39 ABCV34_RS10300 aminodeoxychorismate/anthranilate synthase component II
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS33865 tryptophan synthase alpha chain 0.35 BPHYT_RS17395 anthranilate synthase subunit II 0.88 19
Paraburkholderia sabiae LMG 24235 0.18 QEN71_RS17655 tryptophan synthase subunit alpha 0.35 QEN71_RS27555 aminodeoxychorismate/anthranilate synthase component II 0.93 8
Shewanella amazonensis SB2B 0.18 Sama_2134 trpA tryptophan synthase subunit alpha (RefSeq) 0.36 Sama_3015 para-aminobenzoate synthase glutamine amidotransferase, component II (RefSeq) low > 62
Sphingomonas koreensis DSMZ 15582 0.18 Ga0059261_0239 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.38 Ga0059261_0926 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 0.87 34

Not shown: 5 genomes with orthologs for BBR_RS15810 only; 12 genomes with orthologs for BBR_RS10595 only