Conservation of cofitness between BT0531 and BT3757 in Bacteroides thetaiotaomicron VPI-5482

84 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT0531 anthranilate synthase component II (NCBI ptt file) 1.0 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.76 16
Bacteroides ovatus ATCC 8483 0.96 BACOVA_03781 glutamine amidotransferase, class I 0.92 BACOVA_03587 pyrroline-5-carboxylate reductase 0.87 5
Phocaeicola vulgatus CL09T03C04 0.73 HMPREF1058_RS07180 aminodeoxychorismate/anthranilate synthase component II 0.69 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.87 6
Phocaeicola dorei CL03T12C01 0.72 ABI39_RS21055 aminodeoxychorismate/anthranilate synthase component II 0.69 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.64 24
Parabacteroides merdae CL09T00C40 0.72 HMPREF1078_RS00140 aminodeoxychorismate/anthranilate synthase component II 0.51 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase low > 61
Bacteroides stercoris CC31F 0.66 HMPREF1181_RS15330 aminodeoxychorismate/anthranilate synthase component II 0.78 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.78 51
Echinicola vietnamensis KMM 6221, DSM 17526 0.62 Echvi_2506 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 0.34 Echvi_2479 pyrroline-5-carboxylate reductase 0.44 66
Mucilaginibacter yixingensis YX-36 DSM 26809 0.62 ABZR88_RS16600 aminodeoxychorismate/anthranilate synthase component II 0.39 ABZR88_RS09865 pyrroline-5-carboxylate reductase
Pedobacter sp. GW460-11-11-14-LB5 0.61 CA265_RS22895 aminodeoxychorismate/anthranilate synthase component II 0.34 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.67 34
Pontibacter actiniarum KMM 6156, DSM 19842 0.59 CA264_05060 glutamine amidotransferase 0.33 CA264_07730 pyrroline-5-carboxylate reductase 0.35 25
Castellaniella sp019104865 MT123 0.49 ABCV34_RS10300 aminodeoxychorismate/anthranilate synthase component II 0.19 ABCV34_RS03610 pyrroline-5-carboxylate reductase low > 48
Ralstonia solanacearum UW163 0.49 UW163_RS07135 type 1 glutamine amidotransferase 0.18 UW163_RS08045 pyrroline-5-carboxylate reductase
Pseudomonas sp. S08-1 0.49 OH686_15130 Anthranilate synthase, amidotransferase component or Para-aminobenzoate synthase, amidotransferase component 0.20 OH686_10980 pyrroline-5-carboxylate reductase
Ralstonia solanacearum IBSBF1503 0.49 RALBFv3_RS06490 type 1 glutamine amidotransferase 0.18 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.32 52
Pseudomonas syringae pv. syringae B728a 0.48 Psyr_4581 anthranilate synthase, component II 0.21 Psyr_0476 pyrroline-5-carboxylate reductase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.48 Psyr_4581 anthranilate synthase, component II 0.21 Psyr_0476 pyrroline-5-carboxylate reductase
Pseudomonas fluorescens FW300-N2E3 0.48 AO353_07220 anthranilate synthase 0.21 AO353_08165 pyrroline-5-carboxylate reductase 0.63 57
Ralstonia sp. UNC404CL21Col 0.48 ABZR87_RS02145 aminodeoxychorismate/anthranilate synthase component II 0.19 ABZR87_RS01230 pyrroline-5-carboxylate reductase
Ralstonia solanacearum PSI07 0.48 RPSI07_RS10750 type 1 glutamine amidotransferase 0.18 RPSI07_RS11720 pyrroline-5-carboxylate reductase
Pseudomonas fluorescens FW300-N1B4 0.48 Pf1N1B4_2547 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.20 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_14430 anthranilate synthase 0.22 AO356_13420 pyrroline-5-carboxylate reductase
Pseudomonas sp. RS175 0.48 PFR28_04045 Anthranilate synthase component 2 0.22 PFR28_04243 Pyrroline-5-carboxylate reductase
Pseudomonas fluorescens GW456-L13 0.48 PfGW456L13_1220 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.23 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.82 26
Pseudomonas stutzeri RCH2 0.48 Psest_3649 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 0.23 Psest_0283 pyrroline-5-carboxylate reductase
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_4824 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.21 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
Ralstonia solanacearum GMI1000 0.48 RS_RS14435 type 1 glutamine amidotransferase 0.18 RS_RS13440 pyrroline-5-carboxylate reductase
Pseudomonas simiae WCS417 0.48 PS417_25720 anthranilate synthase component II 0.22 PS417_26730 pyrroline-5-carboxylate reductase 0.52 61
Cupriavidus basilensis FW507-4G11 0.47 RR42_RS18300 anthranilate synthase subunit II 0.17 RR42_RS17360 pyrroline-5-carboxylate reductase
Pseudomonas fluorescens SBW25-INTG 0.47 PFLU_RS27375 aminodeoxychorismate/anthranilate synthase component II 0.23 PFLU_RS28375 pyrroline-5-carboxylate reductase
Pseudomonas fluorescens SBW25 0.47 PFLU_RS27375 aminodeoxychorismate/anthranilate synthase component II 0.23 PFLU_RS28375 pyrroline-5-carboxylate reductase
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS27555 aminodeoxychorismate/anthranilate synthase component II 0.18 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.79 25
Escherichia coli Nissle 1917 0.47 ECOLIN_RS19245 aminodeoxychorismate synthase component 2 0.24 ECOLIN_RS02345 pyrroline-5-carboxylate reductase low > 52
Escherichia fergusonii Becca 0.47 EFB2_00462 Aminodeoxychorismate synthase component 2 0.24 EFB2_03670 Pyrroline-5-carboxylate reductase low > 86
Enterobacter sp. TBS_079 0.47 MPMX20_04263 Aminodeoxychorismate synthase component 2 0.23 MPMX20_00976 Pyrroline-5-carboxylate reductase low > 85
Burkholderia phytofirmans PsJN 0.47 BPHYT_RS17395 anthranilate synthase subunit II 0.19 BPHYT_RS03490 pyrroline-5-carboxylate reductase
Paraburkholderia bryophila 376MFSha3.1 0.47 H281DRAFT_05714 anthranilate synthase, component II 0.19 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.43 33
Paraburkholderia graminis OAS925 0.47 ABIE53_003641 anthranilate synthase component 2 0.20 ABIE53_000840 pyrroline-5-carboxylate reductase
Klebsiella michiganensis M5al 0.47 BWI76_RS26005 glutamine amidotransferase 0.24 BWI76_RS06170 pyrroline-5-carboxylate reductase
Dickeya dadantii 3937 0.47 DDA3937_RS19455 aminodeoxychorismate synthase component II 0.18 DDA3937_RS17305 pyrroline-5-carboxylate reductase
Escherichia coli ECRC98 0.47 JDDGAC_20850 pabA aminodeoxychorismate synthase component 2 0.24 JDDGAC_12265 proC pyrroline-5-carboxylate reductase
Escherichia coli ECOR27 0.47 NOLOHH_09020 pabA aminodeoxychorismate synthase component 2 0.24 NOLOHH_01535 proC pyrroline-5-carboxylate reductase low > 57
Escherichia coli ECRC99 0.47 KEDOAH_10920 pabA aminodeoxychorismate synthase component 2 0.24 KEDOAH_19355 proC pyrroline-5-carboxylate reductase
Escherichia coli BW25113 0.47 b3360 pabA para-aminobenzoate synthase component II (NCBI) 0.24 b0386 proC pyrroline-5-carboxylate reductase (NCBI) low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.47 GFF3709 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.24 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) low > 78
Escherichia coli ECOR38 0.47 HEPCGN_16050 pabA aminodeoxychorismate synthase component 2 0.24 HEPCGN_07250 proC pyrroline-5-carboxylate reductase low > 85
Escherichia coli BL21 0.47 ECD_03211 aminodeoxychorismate synthase, subunit II 0.24 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding low > 60
Escherichia coli ECRC101 0.47 MCAODC_07750 pabA aminodeoxychorismate synthase component 2 0.24 MCAODC_27835 proC pyrroline-5-carboxylate reductase
Escherichia coli ECRC101 0.47 OKFHMN_17220 pabA aminodeoxychorismate synthase component 2 0.24 OKFHMN_08610 proC pyrroline-5-carboxylate reductase
Escherichia coli HS(pFamp)R (ATCC 700891) 0.47 OHPLBJKB_00342 Aminodeoxychorismate synthase component 2 0.24 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase low > 73
Escherichia coli ECRC102 0.47 NIAGMN_14990 pabA aminodeoxychorismate synthase component 2 0.24 NIAGMN_06665 proC pyrroline-5-carboxylate reductase
Escherichia coli ECRC62 0.47 BNILDI_02500 pabA aminodeoxychorismate synthase component 2 0.24 BNILDI_22950 proC pyrroline-5-carboxylate reductase
Herbaspirillum seropedicae SmR1 0.46 HSERO_RS19440 anthranilate synthase subunit II 0.19 HSERO_RS18990 pyrroline-5-carboxylate reductase
Pseudomonas putida KT2440 0.46 PP_0420 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex 0.23 PP_5095 pyrroline-5-carboxylate reductase low > 96
Phaeobacter inhibens DSM 17395 0.46 PGA1_c16880 anthranilate synthase component II 0.11 PGA1_c24700 pyrroline-5-carboxylate reductase ProC
Pectobacterium carotovorum WPP14 0.46 HER17_RS01905 aminodeoxychorismate synthase component II 0.17 HER17_RS03805 pyrroline-5-carboxylate reductase
Enterobacter asburiae PDN3 0.46 EX28DRAFT_4169 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 0.23 EX28DRAFT_2585 pyrroline-5-carboxylate reductase low > 76
Synechococcus elongatus PCC 7942 0.46 Synpcc7942_0400 trpG anthranilate synthase, component II 0.24 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase
Dickeya dianthicola ME23 0.46 DZA65_RS20660 aminodeoxychorismate synthase component II 0.18 DZA65_RS18440 pyrroline-5-carboxylate reductase
Dickeya dianthicola 67-19 0.45 HGI48_RS19575 aminodeoxychorismate synthase component II 0.18 HGI48_RS17350 pyrroline-5-carboxylate reductase
Serratia liquefaciens MT49 0.45 IAI46_23595 aminodeoxychorismate synthase component II 0.18 IAI46_21415 pyrroline-5-carboxylate reductase low > 86
Marinobacter adhaerens HP15 0.45 HP15_3289 para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II 0.21 HP15_287 pyrroline-5-carboxylate reductase low > 73
Rahnella sp. WP5 0.45 EX31_RS04635 aminodeoxychorismate synthase component II 0.15 EX31_RS02690 pyrroline-5-carboxylate reductase low > 89
Variovorax sp. OAS795 0.45 ABID97_RS05260 aminodeoxychorismate/anthranilate synthase component II 0.18 ABID97_RS01555 pyrroline-5-carboxylate reductase
Variovorax sp. SCN45 0.44 GFF5894 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.17 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
Vibrio cholerae E7946 ATCC 55056 0.44 CSW01_13255 aminodeoxychorismate/anthranilate synthase component II 0.20 CSW01_02450 pyrroline-5-carboxylate reductase low > 62
Rhodanobacter sp. FW510-T8 0.44 OKGIIK_12290 pabA anthranilate/aminodeoxychorismate synthase component II 0.16 OKGIIK_11135 proC pyrroline-5-carboxylate reductase low > 52
Caulobacter crescentus NA1000 Δfur 0.43 CCNA_01974 anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II 0.13 CCNA_00528 pyrroline-5-carboxylate reductase low > 67
Dyella japonica UNC79MFTsu3.2 0.43 ABZR86_RS12075 aminodeoxychorismate/anthranilate synthase component II 0.19 ABZR86_RS10425 pyrroline-5-carboxylate reductase
Caulobacter crescentus NA1000 0.43 CCNA_01974 anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II 0.13 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.88 42
Xanthomonas campestris pv. campestris strain 8004 0.43 Xcc-8004.618.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.14 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) low > 74
Lysobacter sp. OAE881 0.43 ABIE51_RS04175 aminodeoxychorismate/anthranilate synthase component II 0.22 ABIE51_RS16065 pyrroline-5-carboxylate reductase low > 62
Rhodanobacter denitrificans FW104-10B01 0.43 LRK54_RS11560 aminodeoxychorismate/anthranilate synthase component II 0.16 LRK54_RS04260 pyrroline-5-carboxylate reductase low > 59
Rhodanobacter denitrificans MT42 0.43 LRK55_RS11290 aminodeoxychorismate/anthranilate synthase component II 0.16 LRK55_RS04030 pyrroline-5-carboxylate reductase
Dinoroseobacter shibae DFL-12 0.43 Dshi_1798 glutamine amidotransferase of anthranilate synthase (RefSeq) 0.11 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq)
Pantoea sp. MT58 0.43 IAI47_01950 aminodeoxychorismate/anthranilate synthase component II 0.21 IAI47_14945 pyrroline-5-carboxylate reductase low > 76
Erwinia tracheiphila SCR3 0.40 LU632_RS22815 aminodeoxychorismate synthase component II 0.24 LU632_RS18995 proC pyrroline-5-carboxylate reductase
Alteromonas macleodii MIT1002 0.40 MIT1002_00439 Para-aminobenzoate synthase glutamine amidotransferase component II 0.23 MIT1002_03062 Pyrroline-5-carboxylate reductase low > 70
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_0926 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 0.16 Ga0059261_3321 pyrroline-5-carboxylate reductase low > 68
Shewanella sp. ANA-3 0.39 Shewana3_0606 aminodeoxychorismate synthase, glutamine amidotransferase subunit (RefSeq) 0.19 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) low > 73
Shewanella loihica PV-4 0.38 Shew_0575 glutamine amidotransferase of anthranilate synthase (RefSeq) 0.21 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) low > 60
Shewanella amazonensis SB2B 0.38 Sama_3015 para-aminobenzoate synthase glutamine amidotransferase, component II (RefSeq) 0.20 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) low > 62
Desulfovibrio vulgaris Hildenborough JW710 0.38 DVU0466 trpG anthranilate synthase, glutamine amidotransferase component (TIGR) 0.21 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.71 45
Shewanella oneidensis MR-1 0.38 SO0613 pabA para-aminobenzoate synthase glutamine amidotransferase, component II (NCBI ptt file) 0.20 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) low > 76
Desulfovibrio vulgaris Miyazaki F 0.36 DvMF_1745 glutamine amidotransferase of anthranilate synthase (RefSeq) 0.22 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.69 35
Bifidobacterium breve UCC2003 0.35 BBR_RS10595 glutamine amidotransferase 0.21 BBR_RS14625 pyrroline-5-carboxylate reductase low > 34

Not shown: 14 genomes with orthologs for BT0531 only; 5 genomes with orthologs for BT3757 only