Conservation of cofitness between b0945 and b2312 in Escherichia coli BW25113

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 1.0 b2312 purF amidophosphoribosyltransferase (NCBI) 0.90 12
Escherichia coli ECRC101 1.00 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 MCAODC_13755 purF amidophosphoribosyltransferase — —
Escherichia coli ECOR27 1.00 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 NOLOHH_14335 purF amidophosphoribosyltransferase low > 57
Escherichia coli ECRC102 1.00 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 NIAGMN_20485 purF amidophosphoribosyltransferase — —
Escherichia coli ECRC101 1.00 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 OKFHMN_22715 purF amidophosphoribosyltransferase — —
Escherichia coli ECRC99 1.00 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 KEDOAH_05480 purF amidophosphoribosyltransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 1.00 OHPLBJKB_01393 Amidophosphoribosyltransferase 0.49 11
Escherichia coli BL21 1.00 ECD_00949 dihydro-orotate oxidase, FMN-linked 1.00 ECD_02237 amidophosphoribosyltransferase 0.73 29
Escherichia coli ECRC98 1.00 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 JDDGAC_26675 purF amidophosphoribosyltransferase — —
Escherichia coli ECRC62 1.00 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 BNILDI_13255 purF amidophosphoribosyltransferase — —
Escherichia coli ECOR38 1.00 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 HEPCGN_21910 purF amidophosphoribosyltransferase low > 85
Escherichia coli Nissle 1917 0.99 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase 1.00 ECOLIN_RS13405 amidophosphoribosyltransferase — —
Escherichia fergusonii Becca 0.99 EFB2_03126 Dihydroorotate dehydrogenase (quinone) 1.00 EFB2_01546 Amidophosphoribosyltransferase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.97 GFF1927 Amidophosphoribosyltransferase (EC 2.4.2.14) low > 78
Enterobacter asburiae PDN3 0.94 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) 0.96 EX28DRAFT_0292 amidophosphoribosyltransferase (EC 2.4.2.14) — —
Enterobacter sp. TBS_079 0.94 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.96 MPMX20_03247 Amidophosphoribosyltransferase 0.82 27
Klebsiella michiganensis M5al 0.93 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.97 BWI76_RS20350 amidophosphoribosyltransferase 0.66 14
Serratia liquefaciens MT49 0.87 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.89 IAI46_17810 amidophosphoribosyltransferase low > 86
Rahnella sp. WP5 0.86 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.88 EX31_RS19570 amidophosphoribosyltransferase 0.93 28
Pectobacterium carotovorum WPP14 0.86 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.91 HER17_RS07020 amidophosphoribosyltransferase 0.94 35
Dickeya dianthicola ME23 0.86 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.88 DZA65_RS15335 amidophosphoribosyltransferase 0.60 74
Dickeya dadantii 3937 0.86 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.88 DDA3937_RS14435 amidophosphoribosyltransferase 0.93 2
Dickeya dianthicola 67-19 0.85 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.88 HGI48_RS14405 amidophosphoribosyltransferase 0.88 2
Erwinia tracheiphila SCR3 0.84 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.91 LU632_RS07865 purF amidophosphoribosyltransferase 0.93 6
Pantoea sp. MT58 0.81 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.89 IAI47_06275 amidophosphoribosyltransferase 0.97 8
Vibrio cholerae E7946 ATCC 55056 0.72 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.76 CSW01_05115 amidophosphoribosyltransferase low > 62
Shewanella sp. ANA-3 0.63 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.73 Shewana3_1483 amidophosphoribosyltransferase (RefSeq) 0.83 60
Shewanella loihica PV-4 0.63 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.74 Shew_2302 amidophosphoribosyltransferase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.62 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.74 Sama_2146 amidophosphoribosyltransferase (RefSeq) 0.64 29
Shewanella oneidensis MR-1 0.62 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.73 SO3064 purF amidophosphoribosyltransferase (NCBI ptt file) 0.86 25
Alteromonas macleodii MIT1002 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.72 MIT1002_02524 Amidophosphoribosyltransferase low > 70
Pseudomonas fluorescens SBW25 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.62 PFLU_RS20515 amidophosphoribosyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.62 PFLU_RS20515 amidophosphoribosyltransferase — —
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase 0.53 QEN71_RS17680 amidophosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.62 AO353_20690 amidophosphoribosyltransferase — —
Burkholderia phytofirmans PsJN 0.57 BPHYT_RS08565 dihydroorotate dehydrogenase 0.56 BPHYT_RS33840 amidophosphoribosyltransferase 0.70 14
Pseudomonas simiae WCS417 0.57 PS417_20935 dihydroorotate dehydrogenase 0.62 PS417_18535 amidophosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_2106 dihydroorotate oxidase A 0.62 Psyr_1668 amidophosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_2106 dihydroorotate oxidase A 0.62 Psyr_1668 amidophosphoribosyltransferase — —
Paraburkholderia graminis OAS925 0.56 ABIE53_001954 dihydroorotate dehydrogenase 0.56 ABIE53_004816 amidophosphoribosyltransferase — —
Pseudomonas sp. RS175 0.56 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.63 PFR28_02811 Amidophosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.62 Pf6N2E2_76 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Pseudomonas fluorescens GW456-L13 0.56 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.62 PfGW456L13_3935 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.62 AO356_21465 amidophosphoribosyltransferase — —
Pseudomonas sp. S08-1 0.55 OH686_03120 dihydroorotate dehydrogenase (fumarate) 0.63 OH686_04420 amidophosphoribosyltransferase — —
Dechlorosoma suillum PS 0.55 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 0.56 Dsui_3186 amidophosphoribosyltransferase — —
Kangiella aquimarina DSM 16071 0.55 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) 0.64 B158DRAFT_1488 amidophosphoribosyltransferase (EC 2.4.2.14) — —
Paraburkholderia bryophila 376MFSha3.1 0.55 H281DRAFT_00743 dihydroorotate oxidase A 0.56 H281DRAFT_06060 amidophosphoribosyltransferase — —
Pseudomonas stutzeri RCH2 0.55 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.62 Psest_2579 amidophosphoribosyltransferase 0.54 11
Ralstonia sp. UNC404CL21Col 0.54 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase 0.59 ABZR87_RS14465 amidophosphoribosyltransferase — —
Pseudomonas putida KT2440 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.63 PP_2000 amidophosphoribosyl transferase — —
Ralstonia solanacearum UW163 0.54 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase 0.58 UW163_RS11175 amidophosphoribosyltransferase — —
Ralstonia solanacearum IBSBF1503 0.54 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase 0.58 RALBFv3_RS02550 amidophosphoribosyltransferase — —
Ralstonia solanacearum GMI1000 0.53 RS_RS08160 dihydroorotate dehydrogenase (quinone) 0.58 RS_RS09930 amidophosphoribosyltransferase — —
Ralstonia solanacearum PSI07 0.53 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase 0.59 RPSI07_RS14765 amidophosphoribosyltransferase — —
Acinetobacter radioresistens SK82 0.53 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.62 MPMX26_01122 Amidophosphoribosyltransferase low > 36
Herbaspirillum seropedicae SmR1 0.52 HSERO_RS16155 dihydroorotate dehydrogenase 0.56 HSERO_RS16445 amidophosphoribosyltransferase — —
Cupriavidus basilensis FW507-4G11 0.51 RR42_RS07465 dihydroorotate dehydrogenase 0.56 RR42_RS14325 amidophosphoribosyltransferase — —
Acidovorax sp. GW101-3H11 0.51 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.55 Ac3H11_2608 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Castellaniella sp019104865 MT123 0.50 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase 0.55 ABCV34_RS04130 amidophosphoribosyltransferase — —
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase 0.59 ABZR86_RS06775 amidophosphoribosyltransferase — —
Rhodanobacter denitrificans MT42 0.50 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase 0.58 LRK55_RS01105 amidophosphoribosyltransferase — —
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase 0.58 LRK54_RS01340 amidophosphoribosyltransferase — —
Variovorax sp. SCN45 0.49 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) 0.53 GFF3089 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Variovorax sp. OAS795 0.48 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase 0.52 ABID97_RS21635 amidophosphoribosyltransferase — —
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase 0.58 OKGIIK_05570 purF amidophosphoribosyltransferase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.47 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.54 GFF300 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Marinobacter adhaerens HP15 0.47 HP15_1377 dihydroorotate dehydrogenase 0.63 HP15_1821 amidophosphoribosyltransferase — —
Xanthomonas campestris pv. campestris strain 8004 0.47 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.58 Xcc-8004.4073.1 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Lysobacter sp. OAE881 0.45 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase 0.58 ABIE51_RS06180 amidophosphoribosyltransferase — —
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS14005 dihydroorotate dehydrogenase (quinone) 0.11 CA265_RS15055 amidophosphoribosyltransferase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.41 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase 0.10 ABZR88_RS15630 class II glutamine amidotransferase — —
Sinorhizobium meliloti 1021 0.40 SMc02245 dihydroorotate dehydrogenase 2 0.28 SMc00554 amidophosphoribosyltransferase 0.93 4
Agrobacterium fabrum C58 0.40 Atu0486 dihydroorotate dehydrogenase 0.29 Atu1075 amidophosphoribosyltransferase 0.90 6
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) 0.28 Ga0059261_3626 amidophosphoribosyltransferase (EC 2.4.2.14) — —
Rhizobium sp. OAE497 0.38 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase 0.29 ABIE40_RS06270 amidophosphoribosyltransferase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.38 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase 0.29 A4249_RS03735 amidophosphoribosyltransferase — —
Rhodopseudomonas palustris CGA009 0.37 TX73_004110 quinone-dependent dihydroorotate dehydrogenase 0.28 TX73_015990 amidophosphoribosyltransferase — —
Azospirillum sp. SherDot2 0.37 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) 0.29 MPMX19_00906 Amidophosphoribosyltransferase — —
Azospirillum brasilense Sp245 0.36 AZOBR_RS13520 dihydroorotate dehydrogenase 0.30 AZOBR_RS08310 amidophosphoribosyltransferase 0.68 8
Magnetospirillum magneticum AMB-1 0.36 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase 0.28 AMB_RS10545 amidophosphoribosyltransferase — —
Rhodospirillum rubrum S1H 0.36 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.30 Rru_A0404 Amidophosphoribosyl transferase (NCBI) low > 58
Mycobacterium tuberculosis H37Rv 0.36 Rv2139 Probable dihydroorotate dehydrogenase PyrD 0.28 Rv0808 Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) — —
Bosea sp. OAE506 0.33 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.29 ABIE41_RS17810 amidophosphoribosyltransferase 0.65 7
Phaeobacter inhibens DSM 17395 0.33 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.28 PGA1_c10810 amidophosphoribosyltransferase PurF 0.87 13
Dinoroseobacter shibae DFL-12 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.27 Dshi_2132 amidophosphoribosyltransferase (RefSeq) 0.81 11
Caulobacter crescentus NA1000 Δfur 0.31 CCNA_00562 dihydroorotate dehydrogenase 0.32 CCNA_01730 amidophosphoribosyltransferase low > 67
Caulobacter crescentus NA1000 0.31 CCNA_00562 dihydroorotate dehydrogenase 0.32 CCNA_01730 amidophosphoribosyltransferase 0.84 42
Bifidobacterium breve UCC2003 0.22 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase 0.29 BBR_RS13380 amidophosphoribosyltransferase low > 34

Not shown: 4 genomes with orthologs for b0945 only; 7 genomes with orthologs for b2312 only