Conservation of cofitness between b2312 and b0945 in Escherichia coli BW25113

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2312 purF amidophosphoribosyltransferase (NCBI) 1.0 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.90 9
Escherichia coli BL21 1.00 ECD_02237 amidophosphoribosyltransferase 1.00 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.73 57
Escherichia coli ECOR27 1.00 NOLOHH_14335 purF amidophosphoribosyltransferase 1.00 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase low > 57
Escherichia coli Nissle 1917 1.00 ECOLIN_RS13405 amidophosphoribosyltransferase 0.99 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECOR38 1.00 HEPCGN_21910 purF amidophosphoribosyltransferase 1.00 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase low > 85
Escherichia coli ECRC102 1.00 NIAGMN_20485 purF amidophosphoribosyltransferase 1.00 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC99 1.00 KEDOAH_05480 purF amidophosphoribosyltransferase 1.00 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC101 1.00 MCAODC_13755 purF amidophosphoribosyltransferase 1.00 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC101 1.00 OKFHMN_22715 purF amidophosphoribosyltransferase 1.00 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia fergusonii Becca 1.00 EFB2_01546 Amidophosphoribosyltransferase 0.99 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Escherichia coli ECRC98 1.00 JDDGAC_26675 purF amidophosphoribosyltransferase 1.00 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC62 1.00 BNILDI_13255 purF amidophosphoribosyltransferase 1.00 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01393 Amidophosphoribosyltransferase 1.00 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 0.49 26
Klebsiella michiganensis M5al 0.97 BWI76_RS20350 amidophosphoribosyltransferase 0.93 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.66 71
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF1927 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.96 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 78
Enterobacter sp. TBS_079 0.96 MPMX20_03247 Amidophosphoribosyltransferase 0.94 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.82 47
Enterobacter asburiae PDN3 0.96 EX28DRAFT_0292 amidophosphoribosyltransferase (EC 2.4.2.14) 0.94 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Erwinia tracheiphila SCR3 0.91 LU632_RS07865 purF amidophosphoribosyltransferase 0.84 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.93 7
Pectobacterium carotovorum WPP14 0.91 HER17_RS07020 amidophosphoribosyltransferase 0.86 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.94 35
Serratia liquefaciens MT49 0.89 IAI46_17810 amidophosphoribosyltransferase 0.87 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase low > 86
Pantoea sp. MT58 0.89 IAI47_06275 amidophosphoribosyltransferase 0.81 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.97 6
Dickeya dadantii 3937 0.88 DDA3937_RS14435 amidophosphoribosyltransferase 0.86 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.93 3
Dickeya dianthicola ME23 0.88 DZA65_RS15335 amidophosphoribosyltransferase 0.86 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.60 58
Dickeya dianthicola 67-19 0.88 HGI48_RS14405 amidophosphoribosyltransferase 0.85 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.88 2
Rahnella sp. WP5 0.88 EX31_RS19570 amidophosphoribosyltransferase 0.86 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.93 13
Vibrio cholerae E7946 ATCC 55056 0.76 CSW01_05115 amidophosphoribosyltransferase 0.72 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.33 57
Shewanella loihica PV-4 0.74 Shew_2302 amidophosphoribosyltransferase (RefSeq) 0.63 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) low > 60
Shewanella amazonensis SB2B 0.74 Sama_2146 amidophosphoribosyltransferase (RefSeq) 0.62 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) low > 62
Shewanella oneidensis MR-1 0.73 SO3064 purF amidophosphoribosyltransferase (NCBI ptt file) 0.62 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.86 25
Shewanella sp. ANA-3 0.73 Shewana3_1483 amidophosphoribosyltransferase (RefSeq) 0.63 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.83 61
Alteromonas macleodii MIT1002 0.72 MIT1002_02524 Amidophosphoribosyltransferase 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) low > 70
Kangiella aquimarina DSM 16071 0.64 B158DRAFT_1488 amidophosphoribosyltransferase (EC 2.4.2.14) 0.55 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) — —
Marinobacter adhaerens HP15 0.63 HP15_1821 amidophosphoribosyltransferase 0.47 HP15_1377 dihydroorotate dehydrogenase — —
Pseudomonas putida KT2440 0.63 PP_2000 amidophosphoribosyl transferase 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas sp. RS175 0.63 PFR28_02811 Amidophosphoribosyltransferase 0.56 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas sp. S08-1 0.63 OH686_04420 amidophosphoribosyltransferase 0.55 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3935 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.56 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas stutzeri RCH2 0.62 Psest_2579 amidophosphoribosyltransferase 0.55 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.54 36
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_21465 amidophosphoribosyltransferase 0.56 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_76 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.56 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Acinetobacter radioresistens SK82 0.62 MPMX26_01122 Amidophosphoribosyltransferase 0.53 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) low > 36
Pseudomonas syringae pv. syringae B728a ΔmexB 0.62 Psyr_1668 amidophosphoribosyltransferase 0.57 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas syringae pv. syringae B728a 0.62 Psyr_1668 amidophosphoribosyltransferase 0.57 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_20690 amidophosphoribosyltransferase 0.57 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens SBW25-INTG 0.62 PFLU_RS20515 amidophosphoribosyltransferase 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.62 PFLU_RS20515 amidophosphoribosyltransferase 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas simiae WCS417 0.62 PS417_18535 amidophosphoribosyltransferase 0.57 PS417_20935 dihydroorotate dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS14465 amidophosphoribosyltransferase 0.54 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.59 ABZR86_RS06775 amidophosphoribosyltransferase 0.50 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.59 RPSI07_RS14765 amidophosphoribosyltransferase 0.53 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS02550 amidophosphoribosyltransferase 0.54 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum UW163 0.58 UW163_RS11175 amidophosphoribosyltransferase 0.54 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.58 RS_RS09930 amidophosphoribosyltransferase 0.53 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Rhodanobacter sp. FW510-T8 0.58 OKGIIK_05570 purF amidophosphoribosyltransferase 0.48 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.58 Xcc-8004.4073.1 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.47 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Rhodanobacter denitrificans MT42 0.58 LRK55_RS01105 amidophosphoribosyltransferase 0.50 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.58 LRK54_RS01340 amidophosphoribosyltransferase 0.49 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Lysobacter sp. OAE881 0.58 ABIE51_RS06180 amidophosphoribosyltransferase 0.45 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase — —
Dechlorosoma suillum PS 0.56 Dsui_3186 amidophosphoribosyltransferase 0.55 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Cupriavidus basilensis FW507-4G11 0.56 RR42_RS14325 amidophosphoribosyltransferase 0.51 RR42_RS07465 dihydroorotate dehydrogenase — —
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS33840 amidophosphoribosyltransferase 0.57 BPHYT_RS08565 dihydroorotate dehydrogenase 0.70 69
Herbaspirillum seropedicae SmR1 0.56 HSERO_RS16445 amidophosphoribosyltransferase 0.52 HSERO_RS16155 dihydroorotate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.56 H281DRAFT_06060 amidophosphoribosyltransferase 0.55 H281DRAFT_00743 dihydroorotate oxidase A — —
Paraburkholderia graminis OAS925 0.56 ABIE53_004816 amidophosphoribosyltransferase 0.56 ABIE53_001954 dihydroorotate dehydrogenase — —
Castellaniella sp019104865 MT123 0.55 ABCV34_RS04130 amidophosphoribosyltransferase 0.50 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.55 Ac3H11_2608 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.51 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.54 GFF300 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.47 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Paraburkholderia sabiae LMG 24235 0.53 QEN71_RS17680 amidophosphoribosyltransferase 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. SCN45 0.53 GFF3089 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.49 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Variovorax sp. OAS795 0.52 ABID97_RS21635 amidophosphoribosyltransferase 0.48 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Caulobacter crescentus NA1000 Δfur 0.32 CCNA_01730 amidophosphoribosyltransferase 0.31 CCNA_00562 dihydroorotate dehydrogenase low > 67
Caulobacter crescentus NA1000 0.32 CCNA_01730 amidophosphoribosyltransferase 0.31 CCNA_00562 dihydroorotate dehydrogenase 0.84 12
Azospirillum brasilense Sp245 0.30 AZOBR_RS08310 amidophosphoribosyltransferase 0.36 AZOBR_RS13520 dihydroorotate dehydrogenase 0.68 12
Rhodospirillum rubrum S1H 0.30 Rru_A0404 Amidophosphoribosyl transferase (NCBI) 0.36 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) low > 58
Azospirillum sp. SherDot2 0.29 MPMX19_00906 Amidophosphoribosyltransferase 0.37 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Bifidobacterium breve UCC2003 0.29 BBR_RS13380 amidophosphoribosyltransferase 0.22 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase 0.76 27
Agrobacterium fabrum C58 0.29 Atu1075 amidophosphoribosyltransferase 0.40 Atu0486 dihydroorotate dehydrogenase 0.90 19
Rhizobium sp. OAE497 0.29 ABIE40_RS06270 amidophosphoribosyltransferase 0.38 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Bosea sp. OAE506 0.29 ABIE41_RS17810 amidophosphoribosyltransferase 0.33 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.65 14
Brevundimonas sp. GW460-12-10-14-LB2 0.29 A4249_RS03735 amidophosphoribosyltransferase 0.38 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase — —
Sinorhizobium meliloti 1021 0.28 SMc00554 amidophosphoribosyltransferase 0.40 SMc02245 dihydroorotate dehydrogenase 2 0.93 26
Phaeobacter inhibens DSM 17395 0.28 PGA1_c10810 amidophosphoribosyltransferase PurF 0.33 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.87 15
Rhodopseudomonas palustris CGA009 0.28 TX73_015990 amidophosphoribosyltransferase 0.37 TX73_004110 quinone-dependent dihydroorotate dehydrogenase — —
Sphingomonas koreensis DSMZ 15582 0.28 Ga0059261_3626 amidophosphoribosyltransferase (EC 2.4.2.14) 0.39 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) — —
Magnetospirillum magneticum AMB-1 0.28 AMB_RS10545 amidophosphoribosyltransferase 0.36 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Mycobacterium tuberculosis H37Rv 0.28 Rv0808 Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.36 Rv2139 Probable dihydroorotate dehydrogenase PyrD — —
Dinoroseobacter shibae DFL-12 0.27 Dshi_2132 amidophosphoribosyltransferase (RefSeq) 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.81 16
Pedobacter sp. GW460-11-11-14-LB5 0.11 CA265_RS15055 amidophosphoribosyltransferase 0.43 CA265_RS14005 dihydroorotate dehydrogenase (quinone) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.10 ABZR88_RS15630 class II glutamine amidotransferase 0.41 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase — —

Not shown: 7 genomes with orthologs for b2312 only; 4 genomes with orthologs for b0945 only