Conservation of cofitness between b2499 and b0908 in Escherichia coli BW25113

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2499 purM phosphoribosylaminoimidazole synthetase (NCBI) 1.0 b0908 aroA 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) 0.83 20
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01227 Phosphoribosylformylglycinamidine cyclo-ligase 1.00 OHPLBJKB_02760 3-phosphoshikimate 1-carboxyvinyltransferase low > 73
Escherichia coli Nissle 1917 1.00 ECOLIN_RS14190 phosphoribosylformylglycinamidine cyclo-ligase 0.98 ECOLIN_RS04810 3-phosphoshikimate 1-carboxyvinyltransferase low > 52
Escherichia coli BL21 1.00 ECD_02391 phosphoribosylaminoimidazole synthetase 1.00 ECD_00912 5-enolpyruvylshikimate-3-phosphate synthetase low > 60
Escherichia coli ECOR38 0.99 HEPCGN_20975 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.98 HEPCGN_23035 aroA 3-phosphoshikimate 1-carboxyvinyltransferase low > 85
Escherichia fergusonii Becca 0.99 EFB2_01399 Phosphoribosylformylglycinamidine cyclo-ligase 0.98 EFB2_03156 3-phosphoshikimate 1-carboxyvinyltransferase low > 86
Escherichia coli ECOR27 0.99 NOLOHH_13460 purM Phosphoribosylformylglycinamidine cyclo-ligase 1.00 NOLOHH_22045 aroA 3-phosphoshikimate 1-carboxyvinyltransferase — —
Escherichia coli ECRC62 0.99 BNILDI_12270 purM Phosphoribosylformylglycinamidine cyclo-ligase 1.00 BNILDI_20300 aroA 3-phosphoshikimate 1-carboxyvinyltransferase — —
Escherichia coli ECRC102 0.99 NIAGMN_19580 purM Phosphoribosylformylglycinamidine cyclo-ligase 1.00 NIAGMN_03205 aroA 3-phosphoshikimate 1-carboxyvinyltransferase — —
Escherichia coli ECRC101 0.99 MCAODC_12340 purM Phosphoribosylformylglycinamidine cyclo-ligase 1.00 MCAODC_24875 aroA 3-phosphoshikimate 1-carboxyvinyltransferase — —
Escherichia coli ECRC101 0.99 OKFHMN_21810 purM Phosphoribosylformylglycinamidine cyclo-ligase 1.00 OKFHMN_05485 aroA 3-phosphoshikimate 1-carboxyvinyltransferase — —
Escherichia coli ECRC98 0.99 JDDGAC_25755 purM Phosphoribosylformylglycinamidine cyclo-ligase 1.00 JDDGAC_09095 aroA 3-phosphoshikimate 1-carboxyvinyltransferase — —
Escherichia coli ECRC99 0.99 KEDOAH_06410 purM Phosphoribosylformylglycinamidine cyclo-ligase 1.00 KEDOAH_22250 aroA 3-phosphoshikimate 1-carboxyvinyltransferase — —
Enterobacter asburiae PDN3 0.94 EX28DRAFT_0168 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.88 EX28DRAFT_2027 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) — —
Enterobacter sp. TBS_079 0.94 MPMX20_03354 Phosphoribosylformylglycinamidine cyclo-ligase 0.88 MPMX20_01567 3-phosphoshikimate 1-carboxyvinyltransferase 0.85 31
Klebsiella michiganensis M5al 0.93 BWI76_RS20965 phosphoribosylformylglycinamidine cyclo-ligase 0.87 BWI76_RS09760 3-phosphoshikimate 1-carboxyvinyltransferase 0.70 58
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2169 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.88 GFF3665 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) low > 78
Rahnella sp. WP5 0.90 EX31_RS22695 phosphoribosylformylglycinamidine cyclo-ligase 0.83 EX31_RS18250 3-phosphoshikimate 1-carboxyvinyltransferase — —
Pantoea sp. MT58 0.89 IAI47_05180 phosphoribosylformylglycinamidine cyclo-ligase 0.83 IAI47_12860 3-phosphoshikimate 1-carboxyvinyltransferase — —
Pectobacterium carotovorum WPP14 0.88 HER17_RS15465 phosphoribosylformylglycinamidine cyclo-ligase 0.78 HER17_RS12285 3-phosphoshikimate 1-carboxyvinyltransferase 0.93 21
Serratia liquefaciens MT49 0.88 IAI46_18885 phosphoribosylformylglycinamidine cyclo-ligase 0.80 IAI46_08640 3-phosphoshikimate 1-carboxyvinyltransferase 0.55 12
Erwinia tracheiphila SCR3 0.87 LU632_RS08275 purM phosphoribosylformylglycinamidine cyclo-ligase 0.79 LU632_RS09795 aroA 3-phosphoshikimate 1-carboxyvinyltransferase 0.63 41
Dickeya dadantii 3937 0.87 DDA3937_RS06025 phosphoribosylformylglycinamidine cyclo-ligase 0.80 DDA3937_RS09675 3-phosphoshikimate 1-carboxyvinyltransferase — —
Dickeya dianthicola ME23 0.86 DZA65_RS06420 phosphoribosylformylglycinamidine cyclo-ligase 0.80 DZA65_RS09995 3-phosphoshikimate 1-carboxyvinyltransferase — —
Dickeya dianthicola 67-19 0.86 HGI48_RS06070 phosphoribosylformylglycinamidine cyclo-ligase 0.79 HGI48_RS09685 3-phosphoshikimate 1-carboxyvinyltransferase — —
Shewanella amazonensis SB2B 0.77 Sama_2097 phosphoribosylaminoimidazole synthetase (RefSeq) 0.67 Sama_1734 3-phosphoshikimate 1-carboxyvinyltransferase (RefSeq) low > 62
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_11350 phosphoribosylformylglycinamidine cyclo-ligase 0.74 CSW01_08705 3-phosphoshikimate 1-carboxyvinyltransferase low > 62
Shewanella sp. ANA-3 0.76 Shewana3_2545 phosphoribosylaminoimidazole synthetase (RefSeq) 0.66 Shewana3_1975 3-phosphoshikimate 1-carboxyvinyltransferase (RefSeq) 0.93 10
Shewanella oneidensis MR-1 0.75 SO2760 purM phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) 0.67 SO2404 aroA 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI ptt file) 0.81 69
Shewanella loihica PV-4 0.75 Shew_1513 phosphoribosylaminoimidazole synthetase (RefSeq) 0.67 Shew_1952 3-phosphoshikimate 1-carboxyvinyltransferase (RefSeq) — —
Alteromonas macleodii MIT1002 0.73 MIT1002_02219 Phosphoribosylformylglycinamidine cyclo-ligase 0.67 MIT1002_02191 3-phosphoshikimate 1-carboxyvinyltransferase — —
Kangiella aquimarina DSM 16071 0.70 B158DRAFT_2385 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.26 B158DRAFT_2432 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) — —
Pseudomonas fluorescens SBW25 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase 0.21 PFLU_RS13540 3-phosphoshikimate 1-carboxyvinyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase 0.21 PFLU_RS13540 3-phosphoshikimate 1-carboxyvinyltransferase — —
Pseudomonas simiae WCS417 0.69 PS417_20120 phosphoribosylaminoimidazole synthetase 0.21 PS417_12855 3-phosphoshikimate 1-carboxyvinyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase 0.24 Psyr_0888 3-phosphoshikimate 1-carboxyvinyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase 0.24 Psyr_0888 3-phosphoshikimate 1-carboxyvinyltransferase — —
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS17220 phosphoribosylaminoimidazole synthetase 0.51 RR42_RS04475 3-phosphoshikimate 1-carboxyvinyltransferase — —
Herbaspirillum seropedicae SmR1 0.56 HSERO_RS03165 phosphoribosylaminoimidazole synthetase 0.52 HSERO_RS18420 3-phosphoshikimate 1-carboxyvinyltransferase — —
Rhodanobacter denitrificans MT42 0.56 LRK55_RS12645 phosphoribosylformylglycinamidine cyclo-ligase 0.16 LRK55_RS00130 3-phosphoshikimate 1-carboxyvinyltransferase low > 63
Rhodospirillum rubrum S1H 0.56 Rru_A2167 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) 0.13 Rru_A0295 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) — —
Rhodanobacter denitrificans FW104-10B01 0.56 LRK54_RS12945 phosphoribosylformylglycinamidine cyclo-ligase 0.15 LRK54_RS00390 3-phosphoshikimate 1-carboxyvinyltransferase — —
Paraburkholderia sabiae LMG 24235 0.55 QEN71_RS26445 phosphoribosylformylglycinamidine cyclo-ligase 0.55 QEN71_RS04085 3-phosphoshikimate 1-carboxyvinyltransferase 0.87 13
Ralstonia solanacearum PSI07 0.55 RPSI07_RS12020 phosphoribosylformylglycinamidine cyclo-ligase 0.51 RPSI07_RS19695 3-phosphoshikimate 1-carboxyvinyltransferase — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS05280 phosphoribosylformylglycinamidine cyclo-ligase 0.51 RALBFv3_RS13775 3-phosphoshikimate 1-carboxyvinyltransferase — —
Ralstonia sp. UNC404CL21Col 0.55 ABZR87_RS00915 phosphoribosylformylglycinamidine cyclo-ligase 0.51 ABZR87_RS09465 3-phosphoshikimate 1-carboxyvinyltransferase — —
Ralstonia solanacearum UW163 0.55 UW163_RS08345 phosphoribosylformylglycinamidine cyclo-ligase 0.51 UW163_RS16035 3-phosphoshikimate 1-carboxyvinyltransferase — —
Burkholderia phytofirmans PsJN 0.54 BPHYT_RS03640 phosphoribosylformylglycinamidine cyclo-ligase 0.56 BPHYT_RS14895 3-phosphoshikimate 1-carboxyvinyltransferase 0.64 30
Ralstonia solanacearum GMI1000 0.54 RS_RS13145 phosphoribosylformylglycinamidine cyclo-ligase 0.51 RS_RS04510 3-phosphoshikimate 1-carboxyvinyltransferase — —
Azospirillum brasilense Sp245 0.54 AZOBR_RS16290 phosphoribosylaminoimidazole synthetase 0.12 AZOBR_RS03090 3-phosphoshikimate 1-carboxyvinyltransferase — —
Xanthomonas campestris pv. campestris strain 8004 0.54 Xcc-8004.1676.1 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.16 Xcc-8004.3281.1 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) 0.76 19
Lysobacter sp. OAE881 0.54 ABIE51_RS15890 phosphoribosylformylglycinamidine cyclo-ligase 0.18 ABIE51_RS12135 3-phosphoshikimate 1-carboxyvinyltransferase — —
Paraburkholderia bryophila 376MFSha3.1 0.54 H281DRAFT_04710 phosphoribosylformylglycinamidine cyclo-ligase 0.56 H281DRAFT_03922 3-phosphoshikimate 1-carboxyvinyltransferase — —
Paraburkholderia graminis OAS925 0.54 ABIE53_000874 phosphoribosylformylglycinamidine cyclo-ligase 0.54 ABIE53_003154 3-phosphoshikimate 1-carboxyvinyltransferase — —
Agrobacterium fabrum C58 0.53 Atu1141 Phosphoribosylglycinamide synthetase 0.23 Atu0642 3-phosphoshikimate 1-carboxyvinyltransferase — —
Azospirillum sp. SherDot2 0.53 MPMX19_01304 Phosphoribosylformylglycinamidine cyclo-ligase 0.12 MPMX19_02233 3-phosphoshikimate 1-carboxyvinyltransferase — —
Synechococcus elongatus PCC 7942 0.53 Synpcc7942_0851 purM phosphoribosylaminoimidazole synthetase 0.16 Synpcc7942_0232 aroA 3-phosphoshikimate 1-carboxyvinyltransferase — —
Dyella japonica UNC79MFTsu3.2 0.53 ABZR86_RS19865 phosphoribosylformylglycinamidine cyclo-ligase 0.17 ABZR86_RS02230 3-phosphoshikimate 1-carboxyvinyltransferase 0.53 43
Rhizobium sp. OAE497 0.52 ABIE40_RS06560 phosphoribosylformylglycinamidine cyclo-ligase 0.24 ABIE40_RS05420 3-phosphoshikimate 1-carboxyvinyltransferase — —
Phaeobacter inhibens DSM 17395 0.52 PGA1_c13260 phosphoribosylformylglycinamidine cyclo-ligase PurM 0.15 PGA1_c04810 3-phosphoshikimate 1-carboxyvinyltransferase AroA — —
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_02315 purM phosphoribosylformylglycinamidine cyclo-ligase 0.17 OKGIIK_06920 aroA 3-phosphoshikimate 1-carboxyvinyltransferase — —
Magnetospirillum magneticum AMB-1 0.52 AMB_RS14330 phosphoribosylformylglycinamidine cyclo-ligase 0.15 AMB_RS21555 3-phosphoshikimate 1-carboxyvinyltransferase — —
Sphingomonas koreensis DSMZ 15582 0.51 Ga0059261_0228 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.14 Ga0059261_0167 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) — —
Sinorhizobium meliloti 1021 0.51 SMc00615 phosphoribosylaminoimidazole synthetase 0.15 SMc00333 3-phosphoshikimate 1-carboxyvinyltransferase — —
Caulobacter crescentus NA1000 0.50 CCNA_01775 phosphoribosylformylglycinamidine cyclo-ligase 0.14 CCNA_03704 3-phosphoshikimate 1-carboxyvinyltransferase — —
Caulobacter crescentus NA1000 Δfur 0.50 CCNA_01775 phosphoribosylformylglycinamidine cyclo-ligase 0.14 CCNA_03704 3-phosphoshikimate 1-carboxyvinyltransferase low > 67
Desulfovibrio vulgaris Miyazaki F 0.49 DvMF_0202 phosphoribosylaminoimidazole synthetase (RefSeq) 0.28 DvMF_1748 3-phosphoshikimate 1-carboxyvinyltransferase (RefSeq) — —
Dinoroseobacter shibae DFL-12 0.49 Dshi_1889 phosphoribosylformylglycinamidine cyclo-ligase (RefSeq) 0.15 Dshi_1022 3-phosphoshikimate 1-carboxyvinyltransferase (RefSeq) — —
Desulfovibrio vulgaris Hildenborough JW710 0.48 DVU1406 purM phosphoribosylformylglycinamidine cyclo-ligase (TIGR) 0.23 DVU0463 aroA 3-phosphoshikimate 1-carboxyvinyltransferase (TIGR) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.48 A4249_RS08210 phosphoribosylformylglycinamidine cyclo-ligase 0.14 A4249_RS10920 3-phosphoshikimate 1-carboxyvinyltransferase — —
Bosea sp. OAE506 0.48 ABIE41_RS17040 phosphoribosylformylglycinamidine cyclo-ligase 0.15 ABIE41_RS03910 3-phosphoshikimate 1-carboxyvinyltransferase — —
Bifidobacterium breve UCC2003 0.47 BBR_RS13375 phosphoribosylformylglycinamidine cyclo-ligase 0.17 BBR_RS14370 3-phosphoshikimate 1-carboxyvinyltransferase low > 34
Fusobacterium nucleatum SB010 0.47 HUW76_05175 phosphoribosylformylglycinamidine cyclo-ligase 0.22 HUW76_05445 3-phosphoshikimate 1-carboxyvinyltransferase low > 35
Rhodopseudomonas palustris CGA009 0.47 TX73_015785 phosphoribosylformylglycinamidine cyclo-ligase 0.16 TX73_000320 3-phosphoshikimate 1-carboxyvinyltransferase — —
Mycobacterium tuberculosis H37Rv 0.40 Rv0809 Probable phosphoribosylformylglycinamidine CYCLO-ligase PurM (AIRS) (phosphoribosyl-aminoimidazole synthetase) (air synthase) 0.17 Rv3227 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) — —
Methanococcus maripaludis S2 0.29 MMP_RS06450 phosphoribosylformylglycinamidine cyclo-ligase 0.27 MMP_RS06205 3-phosphoshikimate 1-carboxyvinyltransferase — —
Methanococcus maripaludis JJ 0.29 MMJJ_RS07900 phosphoribosylformylglycinamidine cyclo-ligase 0.27 MMJJ_RS08145 3-phosphoshikimate 1-carboxyvinyltransferase — —
Bacteroides stercoris CC31F 0.10 HMPREF1181_RS06340 phosphoribosylformylglycinamidine cyclo-ligase 0.26 HMPREF1181_RS09330 3-phosphoshikimate 1-carboxyvinyltransferase low > 56
Parabacteroides merdae CL09T00C40 0.10 HMPREF1078_RS13965 AIR synthase-related protein 0.25 HMPREF1078_RS05635 3-phosphoshikimate 1-carboxyvinyltransferase — —
Phocaeicola dorei CL03T12C01 0.10 ABI39_RS00475 phosphoribosylformylglycinamidine cyclo-ligase 0.24 ABI39_RS09575 3-phosphoshikimate 1-carboxyvinyltransferase low > 72
Bacteroides thetaiotaomicron VPI-5482 0.10 BT4211 putative phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) 0.27 BT2186 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (from data) — —
Phocaeicola vulgatus CL09T03C04 0.10 HMPREF1058_RS08025 phosphoribosylformylglycinamidine cyclo-ligase 0.24 HMPREF1058_RS13970 3-phosphoshikimate 1-carboxyvinyltransferase 0.40 65
Bacteroides ovatus ATCC 8483 0.10 BACOVA_05058 hypothetical protein 0.25 BACOVA_03157 3-phosphoshikimate 1-carboxyvinyltransferase — —
Pedobacter sp. GW460-11-11-14-LB5 0.09 CA265_RS05175 phosphoribosylformylglycinamidine cyclo-ligase 0.23 CA265_RS11640 3-phosphoshikimate 1-carboxyvinyltransferase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.08 Echvi_0734 Phosphoribosylaminoimidazole (AIR) synthetase 0.25 Echvi_0122 5-enolpyruvylshikimate-3-phosphate synthase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.08 CA264_17695 phosphoribosylformylglycinamidine cyclo-ligase 0.21 CA264_13100 3-phosphoshikimate 1-carboxyvinyltransferase low > 74

Not shown: 17 genomes with orthologs for b2499 only; 1 genomes with orthologs for b0908 only