| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_05530 | | two-component system response regulator | cofit | 100 | 100 |
| o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02781 | | Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains | insig. | 32 | 97 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_3168 | | Response regulator | insig. | 34 | 94 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS16850 | | HD domain-containing phosphohydrolase | insig. | 32 | 97 |
| o | Herbaspirillum seropedicae SmR1 | HSERO_RS18645 | | chemotaxis protein CheY | insig. | 34 | 97 |
| o | Paraburkholderia graminis OAS925 | ABIE53_006006 | | adenylate cyclase | sig. | 32 | 97 |
| o | Dechlorosoma suillum PS | Dsui_1886 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 34 | 98 |
| o | Ralstonia solanacearum PSI07 | RPSI07_RS05625 | | two-component system response regulator | insig. | 32 | 97 |
| o | Marinobacter adhaerens HP15 | HP15_3664 | | response regulator receiver modulated metal dependent phosphohydrolase | cofit | 32 | 97 |
| o | Shewanella oneidensis MR-1 | SO2541 | | response regulator (NCBI ptt file) | insig. | 31 | 95 |
| o | Pseudomonas sp. S08-1 | OH686_08945 | | hypothetical protein | cofit | 30 | 96 |
| o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5467 | | Response regulator | sig. | 31 | 95 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS05525 | | response regulator | insig. | 31 | 100 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS05525 | | response regulator | insig. | 31 | 100 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_17715 | | chemotaxis protein CheY | insig. | 30 | 95 |
| o | Pseudomonas simiae WCS417 | PS417_05440 | | chemotaxis protein CheY | insig. | 32 | 97 |
| o | Pseudomonas orientalis W4I3 | QF045_RS08375 | | response regulator | insig. | 31 | 97 |
| o | Pseudomonas putida KT2440 | PP_2942 | | Response regulator | insig. | 30 | 95 |
| o | Pseudomonas fluorescens FW300-N2E3 | AO353_16190 | | chemotaxis protein CheY | insig. | 30 | 95 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01276 | | Regulator of RpoS | cofit | 31 | 99 |
| o | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_788 | | Response regulator | insig. | 31 | 97 |
| o | Pseudomonas sp. RS175 | PFR28_03482 | | Sensor histidine kinase RcsC | cofit | 30 | 95 |
| o | Pseudomonas sp. SVBP6 | COO64_RS20885 | | HD domain-containing phosphohydrolase | insig. | 31 | 95 |
| o | Pseudomonas aeruginosa MRSN321 | DY961_RS04750 | | two-component system response regulator | insig. | 27 | 95 |
| o | Pseudomonas aeruginosa PUPa3 | DQ20_RS35650 | | two-component system response regulator | insig. | 27 | 95 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_12885 | | two-component system response regulator | insig. | 27 | 95 |
| o | Alteromonas macleodii MIT1002 | MIT1002_03637 | | Hydrogenase transcriptional regulatory protein hupR1 | insig. | 29 | 97 |
| | Dechlorosoma suillum PS | Dsui_1890 | | diguanylate cyclase (GGDEF) domain-containing protein | insig. | 36 | 41 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3165 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 36 | 45 |
| | Pseudomonas sp. S08-1 | OH686_08910 | | Phytochrome-like protein / Cph2 | cofit | 44 | 28 |
| | Pseudomonas segetis P6 | MPMX49_02153 | | hypothetical protein | insig. | 46 | 26 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS05355 | | response regulator receiver modulated metal-depenent phosphohydrolase | insig. | 25 | 97 |
| o | Dickeya dianthicola 67-19 | HGI48_RS10210 | | response regulator | insig. | 27 | 96 |
| o | Dickeya dianthicola ME23 | DZA65_RS10630 | | response regulator | insig. | 27 | 96 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09930 | | hybrid sensor histidine kinase/response regulator | cofit | 47 | 28 |
| o | Dickeya dadantii 3937 | DDA3937_RS10180 | | response regulator | insig. | 27 | 94 |
| | Azospirillum sp. SherDot2 | MPMX19_05290 | | Hydrogenase transcriptional regulatory protein hupR1 | insig. | 40 | 30 |
| | Dechlorosoma suillum PS | Dsui_2046 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 43 | 27 |
| | Pseudomonas sp. S08-1 | OH686_08925 | | Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB | cofit | 37 | 34 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS02585 | | response regulator | insig. | 42 | 28 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_14640 | | two-component system response regulator | insig. | 42 | 28 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS33010 | | response regulator | insig. | 42 | 28 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2271 | | His Kinase A (phosphoacceptor) domain./Response regulator receiver domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | strong | 38 | 32 |
| | Dechlorosoma suillum PS | Dsui_3334 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 42 | 27 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2768.1 | | hypothetical protein | strong | 40 | 24 |
| | Lysobacter sp. OAE881 | ABIE51_RS16595 | | EAL domain-containing protein | cofit | 39 | 24 |
| | Pseudomonas sp. S08-1 | OH686_08940 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 35 | 33 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS14555 | | response regulator | strong | 34 | 31 |
| | Xanthobacter sp. DMC5 | GFF4433 | | Hydrogenase transcriptional regulatory protein hupR1 | insig. | 36 | 29 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS11550 | | sigma-54-dependent Fis family transcriptional regulator | insig. | 34 | 29 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS14875 | | response regulator | insig. | 42 | 28 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2210 | | Hydrogenase transcriptional regulatory protein HoxA | insig. | 38 | 29 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS14880 | | response regulator receiver modulated metal-depenent phosphohydrolase | cofit | 39 | 28 |
| | Variovorax sp. OAS795 | ABID97_RS13590 | | sigma-54 dependent transcriptional regulator | insig. | 38 | 29 |
| | Dechlorosoma suillum PS | Dsui_1885 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | insig. | 42 | 28 |
| | Dechlorosoma suillum PS | Dsui_1154 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | insig. | 34 | 29 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2267 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | strong | 36 | 33 |
| | Dickeya dadantii 3937 | DDA3937_RS10185 | | HDOD domain-containing protein | insig. | 33 | 33 |
| | Rhodopseudomonas palustris CGA009 | TX73_005040 | | sigma-54 dependent transcriptional regulator | insig. | 28 | 46 |
| | Shewanella oneidensis MR-1 | SO2539 | | response regulator (NCBI ptt file) | insig. | 40 | 24 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_29820 | | phosphohydrolase | insig. | 25 | 83 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS06195 | | transcriptional regulator | insig. | 25 | 85 |
| | Pseudomonas sp. RS175 | PFR28_01438 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 25 | 83 |
| | Shewanella oneidensis MR-1 | SO0860 | | response regulator (NCBI ptt file) | insig. | 24 | 84 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2900.1 | | response regulator | strong | 26 | 88 |
| | Dickeya dianthicola 67-19 | HGI48_RS10215 | | HDOD domain-containing protein | insig. | 32 | 33 |
| | Lysobacter sp. OAE881 | ABIE51_RS11560 | | two-component system response regulator | strong | 25 | 88 |
| | Shewanella sp. ANA-3 | Shewana3_3418 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 24 | 85 |
| | Rhodospirillum rubrum S1H | Rru_A0692 | | Response regulator receiver domain protein (CheY) (NCBI) | insig. | 40 | 27 |
| | Dickeya dianthicola ME23 | DZA65_RS10635 | | HDOD domain-containing protein | insig. | 31 | 33 |
| | Pseudomonas orientalis W4I3 | QF045_RS08450 | | sigma-54 dependent transcriptional regulator | insig. | 37 | 30 |
| | Azospirillum sp. SherDot2 | MPMX19_06045 | | putative cyclic di-GMP phosphodiesterase | insig. | 25 | 84 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVUA0086 | | response regulator (TIGR) | sig. | 25 | 82 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_16225 | | Fis family transcriptional regulator | insig. | 35 | 30 |
| | Azospirillum brasilense Sp245 | AZOBR_RS23460 | | divalent ion tolerance protein CutA | insig. | 24 | 85 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS00885 | | chemotaxis protein CheY | insig. | 25 | 87 |
| | Shewanella amazonensis SB2B | Sama_2951 | | response regulator receiver protein (RefSeq) | insig. | 23 | 85 |
| | Pseudomonas sp. S08-1 | OH686_00995 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 35 | 28 |
| | Rhodospirillum rubrum S1H | Rru_A0691 | | Predicted signal transduction protein (NCBI) | insig. | 37 | 26 |
| | Ralstonia solanacearum GMI1000 | RS_RS13700 | | response regulator | insig. | 37 | 30 |
| | Dechlorosoma suillum PS | Dsui_3001 | | putative domain HDIG-containing protein | insig. | 23 | 76 |
| | Pseudomonas simiae WCS417 | PS417_05525 | | Fis family transcriptional regulator | strong | 36 | 30 |
| | Dechlorosoma suillum PS | Dsui_3333 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | insig. | 34 | 32 |
| | Dechlorosoma suillum PS | Dsui_3335 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | cofit | 32 | 30 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09200 | | two-component system response regulator | cofit | 24 | 83 |
| | Azospirillum sp. SherDot2 | MPMX19_05749 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 26 | 87 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS05610 | | sigma-54-dependent Fis family transcriptional regulator | strong | 36 | 30 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS05610 | | sigma-54-dependent Fis family transcriptional regulator | strong | 36 | 30 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS05665 | | FAD-dependent oxidoreductase | cofit | 37 | 24 |
| | Paraburkholderia graminis OAS925 | ABIE53_001082 | | two-component system probable response regulator PhcQ | sig. | 37 | 29 |
| | Pseudomonas stutzeri RCH2 | Psest_2701 | | Response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 24 | 81 |
| | Shewanella sp. ANA-3 | Shewana3_0479 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 25 | 84 |
| | Rhodopseudomonas palustris CGA009 | TX73_000745 | | response regulator | insig. | 24 | 82 |
| | Shewanella loihica PV-4 | Shew_3199 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 23 | 85 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02495 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | insig. | 36 | 29 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS05810 | | response regulator | insig. | 36 | 30 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS11490 | | response regulator | insig. | 36 | 30 |
| | Ralstonia solanacearum UW163 | UW163_RS07815 | | response regulator | insig. | 36 | 30 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS01380 | | response regulator | sig. | 36 | 30 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_05525 | | transcriptional regulator | insig. | 38 | 24 |