Conservation of cofitness between OKFHMN_13315 and OKFHMN_24075 in Escherichia coli ECRC100

89 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC100 1.0 OKFHMN_13315 purD Phosphoribosylamine--glycine ligase 1.0 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.91 11
Escherichia coli ECRC99 1.00 KEDOAH_14845 purD Phosphoribosylamine--glycine ligase 1.00 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC98 1.00 JDDGAC_16940 purD Phosphoribosylamine--glycine ligase 1.00 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Escherichia coli ECRC101 1.00 MCAODC_03815 purD Phosphoribosylamine--glycine ligase 1.00 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 87
Escherichia coli ECRC102 1.00 NIAGMN_11065 purD Phosphoribosylamine--glycine ligase 1.00 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC62 0.99 BNILDI_06060 purD Phosphoribosylamine--glycine ligase 1.00 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.77 53
Escherichia coli Nissle 1917 0.99 ECOLIN_RS23095 phosphoribosylamine--glycine ligase 0.98 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECOR27 0.99 NOLOHH_05460 purD Phosphoribosylamine--glycine ligase 1.00 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Escherichia fergusonii Becca 0.99 EFB2_04605 Phosphoribosylamine--glycine ligase 0.99 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 86
Escherichia coli ECOR38 0.99 HEPCGN_11955 purD Phosphoribosylamine--glycine ligase 0.99 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.85 29
Escherichia coli BL21 0.99 ECD_03882 phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase 1.00 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_04044 Phosphoribosylamine--glycine ligase 1.00 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 73
Escherichia coli BW25113 0.98 b4005 purD phosphoribosylamine--glycine ligase (NCBI) 1.00 b2103 thiD phosphomethylpyrimidine kinase (NCBI) low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF4187 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.92 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 78
Klebsiella michiganensis M5al 0.92 BWI76_RS01610 phosphoribosylamine--glycine ligase 0.92 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 92
Enterobacter sp. TBS_079 0.92 MPMX20_00225 Phosphoribosylamine--glycine ligase 0.91 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 85
Enterobacter asburiae PDN3 0.92 EX28DRAFT_4544 phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.90 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Pantoea sp. MT58 0.84 IAI47_18045 phosphoribosylamine--glycine ligase 0.76 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Dickeya dadantii 3937 0.83 DDA3937_RS01215 phosphoribosylamine--glycine ligase 0.76 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Dickeya dianthicola ME23 0.83 DZA65_RS01255 phosphoribosylamine--glycine ligase 0.75 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Dickeya dianthicola 67-19 0.83 HGI48_RS01210 phosphoribosylamine--glycine ligase 0.76 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 71
Rahnella sp. WP5 0.82 EX31_RS16855 phosphoribosylamine--glycine ligase 0.79 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 89
Pectobacterium carotovorum WPP14 0.82 HER17_RS20340 phosphoribosylamine--glycine ligase 0.79 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Erwinia tracheiphila SCR3 0.81 LU632_RS01015 purD phosphoribosylamine--glycine ligase 0.76 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Serratia liquefaciens MT49 0.81 IAI46_01360 phosphoribosylamine--glycine ligase 0.78 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_01415 phosphoribosylamine--glycine ligase 0.40 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 62
Pseudomonas putida KT2440 0.74 PP_4823 Phosphoribosylamine--glycine ligase 0.22 PP_4782 Phosphomethylpyrimidine kinase — —
Pseudomonas sp. RS175 0.73 PFR28_05213 Phosphoribosylamine--glycine ligase 0.20 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Pseudomonas fluorescens FW300-N2C3 0.73 AO356_08230 phosphoribosylamine--glycine ligase 0.22 AO356_15435 hydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.73 Pf6N2E2_3520 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.18 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Pseudomonas syringae pv. syringae B728a 0.73 Psyr_4407 phosphoribosylamine--glycine ligase 0.22 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.73 Psyr_4407 phosphoribosylamine--glycine ligase 0.22 Psyr_4340 phosphomethylpyrimidine kinase, putative — —
Pseudomonas fluorescens SBW25-INTG 0.73 PFLU_RS03010 phosphoribosylamine--glycine ligase 0.24 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Pseudomonas fluorescens SBW25 0.73 PFLU_RS03010 phosphoribosylamine--glycine ligase 0.24 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Pseudomonas stutzeri RCH2 0.73 Psest_1013 phosphoribosylamine--glycine ligase 0.21 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 67
Pseudomonas fluorescens FW300-N2E3 0.73 AO353_13645 phosphoribosylamine--glycine ligase 0.23 AO353_06350 hydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.73 Pf1N1B4_1316 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.18 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Pseudomonas fluorescens GW456-L13 0.72 PfGW456L13_58 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.22 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Pseudomonas simiae WCS417 0.72 PS417_02935 phosphoribosylamine--glycine ligase 0.24 PS417_24600 hydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.67 Xcc-8004.657.1 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.30 Xcc-8004.3091.1 hypothetical protein low > 74
Dyella japonica UNC79MFTsu3.2 0.65 ABZR86_RS13850 phosphoribosylamine--glycine ligase 0.29 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Acinetobacter radioresistens SK82 0.65 MPMX26_01140 Phosphoribosylamine--glycine ligase 0.22 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Rhodanobacter sp. FW510-T8 0.63 OKGIIK_13750 purD phosphoribosylamine--glycine ligase 0.23 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 52
Dechlorosoma suillum PS 0.62 Dsui_1596 phosphoribosylamine--glycine ligase 0.26 Dsui_0662 phosphomethylpyrimidine kinase — —
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS17755 phosphoribosylamine--glycine ligase 0.19 HSERO_RS02135 phosphomethylpyrimidine kinase — —
Paraburkholderia graminis OAS925 0.60 ABIE53_001545 phosphoribosylamine--glycine ligase 0.51 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Paraburkholderia bryophila 376MFSha3.1 0.60 H281DRAFT_04521 phosphoribosylamine--glycine ligase 0.54 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase — —
Burkholderia phytofirmans PsJN 0.59 BPHYT_RS06405 phosphoribosylamine--glycine ligase 0.53 BPHYT_RS12250 phosphomethylpyrimidine kinase — —
Ralstonia solanacearum GMI1000 0.59 RS_RS10995 phosphoribosylamine--glycine ligase 0.35 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum PSI07 0.59 RPSI07_RS13680 phosphoribosylamine--glycine ligase 0.34 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Paraburkholderia sabiae LMG 24235 0.59 QEN71_RS24400 phosphoribosylamine--glycine ligase 0.54 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Acidovorax sp. GW101-3H11 0.59 Ac3H11_2421 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.33 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Ralstonia sp. UNC404CL21Col 0.58 ABZR87_RS15410 phosphoribosylamine--glycine ligase 0.36 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS03545 phosphoribosylamine--glycine ligase 0.34 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.58 GFF4524 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.39 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Ralstonia solanacearum UW163 0.58 UW163_RS10125 phosphoribosylamine--glycine ligase 0.34 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Castellaniella sp019104865 MT123 0.57 ABCV34_RS02550 phosphoribosylamine--glycine ligase 0.43 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Cupriavidus basilensis FW507-4G11 0.57 RR42_RS04730 phosphoribosylamine--glycine ligase 0.32 RR42_RS01370 phosphomethylpyrimidine kinase — —
Variovorax sp. OAS795 0.56 ABID97_RS16735 phosphoribosylamine--glycine ligase 0.34 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Agrobacterium fabrum C58 0.55 Atu0647 phosphoribosylamine--glycine ligase 0.45 Atu3290 phosphomethylpyrimidine kinase 0.70 64
Rhizobium sp. OAE497 0.55 ABIE40_RS05430 phosphoribosylamine--glycine ligase 0.49 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 107
Azospirillum sp. SherDot2 0.53 MPMX19_01630 Phosphoribosylamine--glycine ligase 0.36 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Azospirillum brasilense Sp245 0.53 AZOBR_RS04470 phosphoribosylamine--glycine ligase 0.37 AZOBR_RS07045 phosphomethylpyrimidine kinase — —
Rhodopseudomonas palustris CGA009 0.53 TX73_005965 phosphoribosylamine--glycine ligase 0.49 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Magnetospirillum magneticum AMB-1 0.53 AMB_RS01075 phosphoribosylamine--glycine ligase 0.31 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Sinorhizobium meliloti 1021 0.52 SMc00993 phosphoribosylamine--glycine ligase 0.44 SM_b20962 phoshomethylpyrimidine kinase low > 103
Bosea sp. OAE506 0.50 ABIE41_RS23160 phosphoribosylamine--glycine ligase 0.45 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Desulfovibrio vulgaris Miyazaki F 0.49 DvMF_1722 phosphoribosylamine--glycine ligase (RefSeq) 0.28 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) — —
Desulfovibrio vulgaris Hildenborough JW710 0.49 DVU0488 purD phosphoribosylamine--glycine ligase (TIGR) 0.27 DVU0931 thiD phosphomethylpyrimidine kinase (TIGR) — —
Rhodospirillum rubrum S1H 0.48 Rru_A0646 Phosphoribosylamine--glycine ligase (NCBI) 0.39 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) — —
Phaeobacter inhibens DSM 17395 0.47 PGA1_c23610 phosphoribosylamine--glycine ligase PurD 0.16 PGA1_c09030 phosphomethylpyrimidine kinase ThiD low > 62
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS06805 phosphoribosylamine--glycine ligase 0.42 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 61
Dinoroseobacter shibae DFL-12 0.45 Dshi_2728 phosphoribosylamine--glycine ligase (RefSeq) 0.37 Dshi_0915 phosphomethylpyrimidine kinase (RefSeq) low > 64
Phocaeicola vulgatus CL09T03C04 0.44 HMPREF1058_RS10995 phosphoribosylamine--glycine ligase 0.39 HMPREF1058_RS06820 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 67
Sphingomonas koreensis DSMZ 15582 0.44 Ga0059261_1441 phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.24 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Bacteroides stercoris CC31F 0.44 HMPREF1181_RS01580 phosphoribosylamine--glycine ligase 0.39 HMPREF1181_RS14705 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 56
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_0167 phosphoribosylamine--glycine ligase 0.35 Echvi_0215 phosphomethylpyrimidine kinase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.44 A4249_RS09255 phosphoribosylamine--glycine ligase 0.28 A4249_RS15985 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Phocaeicola dorei CL03T12C01 0.44 ABI39_RS06055 phosphoribosylamine--glycine ligase 0.38 ABI39_RS20615 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 72
Caulobacter crescentus NA1000 Δfur 0.44 CCNA_00299 phosphoribosylamine--glycine ligase 0.33 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Caulobacter crescentus NA1000 0.44 CCNA_00299 phosphoribosylamine--glycine ligase 0.33 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Fusobacterium nucleatum SB010 0.43 HUW76_05205 phosphoribosylamine--glycine ligase 0.31 HUW76_10300 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 35
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS01620 phosphoribosylamine--glycine ligase 0.32 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Synechococcus elongatus PCC 7942 0.43 Synpcc7942_0925 purD phosphoribosylamine--glycine ligase 0.24 Synpcc7942_2379 thiD phosphomethylpyrimidine kinase — —
Bacteroides thetaiotaomicron VPI-5482 0.43 BT3253 phosphoribosylamine--glycine ligase (NCBI ptt file) 0.37 BT0790 phosphomethylpyrimidine kinase (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.43 BACOVA_01348 phosphoribosylamine--glycine ligase 0.36 BACOVA_02530 phosphomethylpyrimidine kinase 0.73 74
Bifidobacterium breve UCC2003 0.42 BBR_RS13370 phosphoribosylamine--glycine ligase 0.33 BBR_RS17215 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 34
Pontibacter actiniarum KMM 6156, DSM 19842 0.42 CA264_20115 phosphoribosylamine--glycine ligase 0.19 CA264_20430 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.39 CA265_RS22605 phosphoribosylamine--glycine ligase 0.34 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Mycobacterium tuberculosis H37Rv 0.35 Rv0772 Probable phosphoribosylamine--glycine ligase PurD (GARS) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase) (5'-phosphoribosylglycinamide synthetase) 0.26 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) — —

Not shown: 14 genomes with orthologs for OKFHMN_13315 only; 0 genomes with orthologs for OKFHMN_24075 only