Conservation of cofitness between PS417_23915 and PS417_26775 in Pseudomonas simiae WCS417

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas simiae WCS417 1.0 PS417_23915 pantoate--beta-alanine ligase 1.0 PS417_26775 thiazole synthase 0.62 2
Pseudomonas fluorescens SBW25-INTG 0.98 PFLU_RS25755 pantoate--beta-alanine ligase 1.00 PFLU_RS28420 thiazole synthase low > 109
Pseudomonas fluorescens SBW25 0.98 PFLU_RS25755 pantoate--beta-alanine ligase 1.00 PFLU_RS28420 thiazole synthase low > 109
Pseudomonas fluorescens FW300-N1B4 0.85 Pf1N1B4_2853 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.95 Pf1N1B4_2331 Thiazole biosynthesis protein ThiG 0.25 85
Pseudomonas fluorescens FW300-N2E2 0.84 Pf6N2E2_5152 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.95 Pf6N2E2_4590 Thiazole biosynthesis protein ThiG — —
Pseudomonas sp. RS175 0.84 PFR28_03722 Pantothenate synthetase 0.95 PFR28_04252 Thiazole synthase — —
Pseudomonas fluorescens GW456-L13 0.84 PfGW456L13_1520 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.99 PfGW456L13_1000 Thiazole biosynthesis protein ThiG 0.42 9
Pseudomonas fluorescens FW300-N2C3 0.84 AO356_16055 pantoate--beta-alanine ligase 0.95 AO356_13375 thiazole synthase — —
Pseudomonas fluorescens FW300-N2E3 0.84 AO353_14380 pantoate--beta-alanine ligase 0.95 AO353_08215 thiazole synthase low > 101
Pseudomonas putida KT2440 0.80 PP_4700 pantothenate synthetase 0.91 PP_5104 thiazole synthase low > 96
Pseudomonas syringae pv. syringae B728a 0.78 Psyr_0827 pantothenate synthetase 0.91 Psyr_4740 thiazole-phosphate synthase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.78 Psyr_0827 pantothenate synthetase 0.91 Psyr_4740 thiazole-phosphate synthase low > 86
Pseudomonas sp. S08-1 0.72 OH686_17240 pantoate--beta-alanine ligase 0.88 OH686_14285 Thiazole synthase — —
Pseudomonas stutzeri RCH2 0.69 Psest_0995 pantoate--beta-alanine ligase 0.87 Psest_0267 Uncharacterized enzyme of thiazole biosynthesis — —
Marinobacter adhaerens HP15 0.62 HP15_323 pantothenate synthetase 0.72 HP15_3274 thiazole synthase — —
Alteromonas macleodii MIT1002 0.55 MIT1002_03695 Pantothenate synthetase 0.38 MIT1002_00093 Thiazole synthase — —
Shewanella amazonensis SB2B 0.51 Sama_0775 panC pantoate--beta-alanine ligase (RefSeq) 0.38 Sama_1856 thiG thiazole synthase (RefSeq) — —
Kangiella aquimarina DSM 16071 0.51 B158DRAFT_0062 pantoate--beta-alanine ligase 0.37 B158DRAFT_0291 thiazole-phosphate synthase — —
Shewanella loihica PV-4 0.51 Shew_3134 pantoate--beta-alanine ligase (RefSeq) 0.36 Shew_2092 thiazole biosynthesis family protein (RefSeq) — —
Escherichia fergusonii Becca 0.50 EFB2_03911 Pantothenate synthetase 0.38 EFB2_04621 Thiazole synthase low > 86
Escherichia coli ECRC101 0.50 MCAODC_00920 panC pantoate--beta-alanine ligase 0.38 MCAODC_03895 thiG thiazole synthase — —
Escherichia coli ECRC101 0.50 OKFHMN_10405 panC pantoate--beta-alanine ligase 0.38 OKFHMN_13395 thiG thiazole synthase — —
Escherichia coli ECRC99 0.50 KEDOAH_17750 panC pantoate--beta-alanine ligase 0.38 KEDOAH_14765 thiG thiazole synthase — —
Escherichia coli ECRC102 0.50 NIAGMN_08255 panC pantoate--beta-alanine ligase 0.38 NIAGMN_11145 thiG thiazole synthase — —
Escherichia coli ECOR38 0.50 HEPCGN_08380 panC pantoate--beta-alanine ligase 0.38 HEPCGN_12030 thiG thiazole synthase low > 85
Escherichia coli ECRC98 0.50 JDDGAC_14000 panC pantoate--beta-alanine ligase 0.38 JDDGAC_17020 thiG thiazole synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.50 OHPLBJKB_03528 Pantothenate synthetase 0.38 OHPLBJKB_04060 Thiazole synthase low > 73
Escherichia coli BW25113 0.50 b0133 panC pantoate--beta-alanine ligase (NCBI) 0.38 b3991 thiG thiamin biosynthesis, thiazole moiety (VIMSS) 0.35 43
Escherichia coli ECRC62 0.50 BNILDI_08920 panC pantoate--beta-alanine ligase 0.38 BNILDI_05985 thiG thiazole synthase — —
Serratia liquefaciens MT49 0.50 IAI46_21245 pantoate--beta-alanine ligase 0.37 IAI46_01300 thiazole synthase low > 86
Shewanella oneidensis MR-1 0.50 SO0869 panC pantoate--beta-alanine ligase (NCBI ptt file) 0.35 SO2441 thiG thiG protein (NCBI ptt file) — —
Escherichia coli ECOR27 0.50 NOLOHH_02750 panC pantoate--beta-alanine ligase 0.38 NOLOHH_05540 thiG thiazole synthase low > 57
Escherichia coli BL21 0.50 ECD_00132 pantothenate synthetase 0.38 ECD_03867 thiamine biosynthesis ThiGH complex subunit low > 60
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF92 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.37 GFF4202 Thiazole biosynthesis protein ThiG 0.34 68
Vibrio cholerae E7946 ATCC 55056 0.50 CSW01_03130 pantoate--beta-alanine ligase 0.39 CSW01_00355 thiazole synthase — —
Acinetobacter radioresistens SK82 0.49 MPMX26_00546 Pantothenate synthetase 0.69 MPMX26_01107 Thiazole synthase — —
Klebsiella michiganensis M5al 0.49 BWI76_RS04990 pantoate--beta-alanine ligase 0.38 BWI76_RS01535 thiazole synthase 0.35 39
Shewanella sp. ANA-3 0.49 Shewana3_3409 panC pantoate--beta-alanine ligase (RefSeq) 0.37 Shewana3_1940 thiG thiazole synthase (RefSeq) — —
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS00820 pantoate--beta-alanine ligase 0.71 ABZR86_RS11645 thiazole synthase — —
Pectobacterium carotovorum WPP14 0.49 HER17_RS05555 pantoate--beta-alanine ligase 0.39 HER17_RS20400 thiazole synthase 0.86 37
Erwinia tracheiphila SCR3 0.49 LU632_RS20105 panC pantoate--beta-alanine ligase 0.36 LU632_RS00950 thiazole synthase low > 74
Dickeya dadantii 3937 0.49 DDA3937_RS15960 pantoate--beta-alanine ligase 0.38 DDA3937_RS01155 thiazole synthase low > 74
Rahnella sp. WP5 0.48 EX31_RS03285 pantoate--beta-alanine ligase 0.38 EX31_RS16795 thiazole synthase low > 89
Dickeya dianthicola ME23 0.48 DZA65_RS17160 pantoate--beta-alanine ligase 0.38 DZA65_RS01195 thiazole synthase 0.72 56
Lysobacter sp. OAE881 0.48 ABIE51_RS08030 pantoate--beta-alanine ligase 0.71 ABIE51_RS16545 thiazole synthase — —
Pantoea sp. MT58 0.48 IAI47_15660 pantoate--beta-alanine ligase 0.32 IAI47_20700 thiazole synthase low > 76
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_03890 panC pantoate--beta-alanine ligase 0.68 OKGIIK_11895 thiS thiazole synthase low > 52
Dickeya dianthicola 67-19 0.47 HGI48_RS16075 pantoate--beta-alanine ligase 0.37 HGI48_RS01150 thiazole synthase low > 71
Enterobacter asburiae PDN3 0.46 EX28DRAFT_3729 pantoate--beta-alanine ligase 0.36 EX28DRAFT_4532 Uncharacterized enzyme of thiazole biosynthesis low > 76
Enterobacter sp. TBS_079 0.46 MPMX20_00826 Pantothenate synthetase 0.36 MPMX20_00213 Thiazole synthase low > 85
Dechlorosoma suillum PS 0.46 Dsui_1470 pantoate--beta-alanine ligase 0.69 Dsui_1014 putative enzyme of thiazole biosynthesis — —
Dinoroseobacter shibae DFL-12 0.44 Dshi_2952 pantoate--beta-alanine ligase (RefSeq) 0.29 Dshi_0912 thiazole biosynthesis family protein (RefSeq) — —
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS15520 pantoate--beta-alanine ligase 0.66 HSERO_RS02130 thiazole synthase — —
Sinorhizobium meliloti 1021 0.44 SMc01880 pantoate--beta-alanine ligase 0.29 SM_b20617 thiazole synthase — —
Ralstonia solanacearum GMI1000 0.44 RS_RS11985 pantoate--beta-alanine ligase 0.36 RS_RS00535 thiazole synthase — —
Azospirillum brasilense Sp245 0.44 AZOBR_RS09715 pantoate--beta-alanine ligase 0.41 AZOBR_RS30960 thiazole synthase — —
Ralstonia solanacearum UW163 0.43 UW163_RS09235 pantoate--beta-alanine ligase 0.36 UW163_RS03655 thiazole synthase — —
Ralstonia solanacearum IBSBF1503 0.43 RALBFv3_RS04435 pantoate--beta-alanine ligase 0.36 RALBFv3_RS09925 thiazole synthase — —
Agrobacterium fabrum C58 0.43 Atu3482 pantoate--beta-alanine ligase 0.33 Atu2566 thiamin biosynthesis ThiG low > 89
Variovorax sp. SCN45 0.43 GFF2578 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.35 GFF1188 Thiazole synthase (EC 2.8.1.10) low > 127
Xanthomonas campestris pv. campestris strain 8004 0.43 Xcc-8004.3051.1 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.70 Xcc-8004.1284.1 Thiazole biosynthesis protein ThiG — —
Caulobacter crescentus NA1000 Δfur 0.43 CCNA_02247 pantoate-beta-alanine ligase 0.57 CCNA_01957 thiazole biosynthesis protein ThiG — —
Caulobacter crescentus NA1000 0.43 CCNA_02247 pantoate-beta-alanine ligase 0.57 CCNA_01957 thiazole biosynthesis protein ThiG — —
Paraburkholderia sabiae LMG 24235 0.42 QEN71_RS25065 pantoate--beta-alanine ligase 0.35 QEN71_RS27930 thiazole synthase — —
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS00030 pantoate--beta-alanine ligase 0.37 ABZR87_RS04800 thiazole synthase — —
Ralstonia solanacearum PSI07 0.42 RPSI07_RS12935 pantoate--beta-alanine ligase 0.37 RPSI07_RS23435 thiazole synthase — —
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS16055 pantothenate synthetase 0.36 RR42_RS01305 thiazole synthase — —
Paraburkholderia graminis OAS925 0.42 ABIE53_001260 pantoate--beta-alanine ligase 0.34 ABIE53_003714 thiazole synthase — —
Variovorax sp. OAS795 0.42 ABID97_RS07430 pantoate--beta-alanine ligase 0.36 ABID97_RS15315 thiazole synthase low > 91
Bosea sp. OAE506 0.41 ABIE41_RS14875 pantoate--beta-alanine ligase 0.32 ABIE41_RS20185 thiazole synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.41 H281DRAFT_00150 pantothenate synthetase 0.34 H281DRAFT_05639 thiazole-phosphate synthase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.41 A4249_RS06825 pantoate--beta-alanine ligase 0.53 A4249_RS07975 thiazole synthase — —
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS04925 pantothenate synthetase 0.34 BPHYT_RS17775 thiazole synthase — —
Rhodopseudomonas palustris CGA009 0.41 TX73_016310 pantoate--beta-alanine ligase 0.34 TX73_018530 thiazole synthase — —
Azospirillum sp. SherDot2 0.41 MPMX19_04465 Pantothenate synthetase 0.43 MPMX19_00262 Thiazole synthase 0.53 101
Castellaniella sp019104865 MT123 0.40 ABCV34_RS14585 pantoate--beta-alanine ligase 0.67 ABCV34_RS14510 thiazole synthase — —
Bacteroides stercoris CC31F 0.40 HMPREF1181_RS06090 pantoate--beta-alanine ligase 0.35 HMPREF1181_RS14680 thiazole synthase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS18500 pantoate--beta-alanine ligase 0.35 ABZR88_RS08825 thiazole synthase — —
Bacteroides ovatus ATCC 8483 0.39 BACOVA_05108 pantoate--beta-alanine ligase 0.36 BACOVA_02359 thiazole biosynthesis protein ThiG — —
Bacteroides thetaiotaomicron VPI-5482 0.39 BT4308 pantoate--beta-alanine ligase (NCBI ptt file) 0.36 BT0651 thiamine biosynthesis protein ThiG (NCBI ptt file) — —
Desulfovibrio vulgaris Miyazaki F 0.38 DvMF_2942 panC pantoate--beta-alanine ligase (RefSeq) 0.33 DvMF_0800 thiG thiazole synthase (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.37 PGA1_c32040 pantothenate synthetase PanC 0.33 PGA1_c09070 thiazole biosynthesis protein ThiG — —
Phocaeicola vulgatus CL09T03C04 0.37 HMPREF1058_RS18260 pantoate--beta-alanine ligase 0.37 HMPREF1058_RS03285 thiazole synthase — —
Phocaeicola dorei CL03T12C01 0.37 ABI39_RS14555 pantoate--beta-alanine ligase 0.37 ABI39_RS17755 thiazole synthase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.36 CA264_17615 pantoate--beta-alanine ligase 0.40 CA264_20420 thiazole synthase — —
Pedobacter sp. GW460-11-11-14-LB5 0.36 CA265_RS22700 pantoate--beta-alanine ligase 0.37 CA265_RS20180 thiazole synthase — —
Desulfovibrio vulgaris Hildenborough JW710 0.36 DVU2448 panC pantoate--beta-alanine ligase (TIGR) 0.34 DVU2094 thiG thiG protein (TIGR) 0.20 35
Acidovorax sp. GW101-3H11 0.36 Ac3H11_3840 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.32 Ac3H11_1059 Thiazole biosynthesis protein ThiG — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.36 Echvi_1527 pantoate--beta-alanine ligase 0.39 Echvi_3564 Uncharacterized enzyme of thiazole biosynthesis — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF1220 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.34 GFF246 Thiazole biosynthesis protein ThiG — —
Mycobacterium tuberculosis H37Rv 0.33 Rv3602c Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.44 Rv0417 Probable thiamin biosynthesis protein ThiG (thiazole biosynthesis protein) — —

Not shown: 7 genomes with orthologs for PS417_23915 only; 4 genomes with orthologs for PS417_26775 only