| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Sphingobium sp. HT1-2 | 1.0 | GFF217 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 1.0 | GFF2056 | | Acetolactate synthase small subunit (EC 2.2.1.6) | 0.85 | 25 |
| Sphingomonas koreensis DSMZ 15582 | 0.74 | Ga0059261_0992 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.73 | Ga0059261_0067 | | acetolactate synthase, small subunit (EC 2.2.1.6) | 0.63 | 51 |
| Rhodospirillum rubrum S1H | 0.59 | Rru_A1530 | | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.63 | Rru_A0468 | | Acetolactate synthase, small subunit (NCBI) | 0.87 | 22 |
| Azospirillum brasilense Sp245 | 0.59 | AZOBR_RS09540 | | 5 10-methylenetetrahydrofolate reductase | 0.65 | AZOBR_RS06565 | | acetolactate synthase | low | > 97 |
| Magnetospirillum magneticum AMB-1 | 0.58 | AMB_RS02230 | | methylenetetrahydrofolate reductase | 0.58 | AMB_RS17745 | | acetolactate synthase small subunit | — | — |
| Xanthobacter sp. DMC5 | 0.57 | GFF4147 | | 5,10-methylenetetrahydrofolate reductase | 0.59 | GFF171 | | Acetolactate synthase small subunit | — | — |
| Azospirillum sp. SherDot2 | 0.56 | MPMX19_00635 | | 5,10-methylenetetrahydrofolate reductase | 0.64 | MPMX19_01775 | | Acetolactate synthase isozyme 3 small subunit | — | — |
| Pectobacterium carotovorum WPP14 | 0.55 | HER17_RS00950 | | methylenetetrahydrofolate reductase | 0.41 | HER17_RS03100 | | acetolactate synthase small subunit | low | > 75 |
| Dickeya dianthicola ME23 | 0.54 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | 0.42 | DZA65_RS19180 | | acetolactate synthase small subunit | low | > 75 |
| Dickeya dianthicola 67-19 | 0.54 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | 0.42 | HGI48_RS18035 | | acetolactate synthase small subunit | low | > 71 |
| Dickeya dadantii 3937 | 0.54 | DDA3937_RS00960 | | methylenetetrahydrofolate reductase | 0.42 | DDA3937_RS18100 | | acetolactate synthase small subunit | low | > 74 |
| Bosea sp. OAE506 | 0.54 | ABIE41_RS12475 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.58 | ABIE41_RS12905 | | acetolactate synthase small subunit | — | — |
| Rahnella sp. WP5 | 0.54 | EX31_RS14205 | | methylenetetrahydrofolate reductase | 0.40 | EX31_RS03660 | | acetolactate synthase small subunit | low | > 89 |
| Shewanella oneidensis MR-1 | 0.54 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.42 | SO2278 | ilvH | acetolactate synthase III, small subunit (NCBI ptt file) | — | — |
| Shewanella sp. ANA-3 | 0.54 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.42 | Shewana3_2270 | ilvH | acetolactate synthase 3 regulatory subunit (RefSeq) | low | > 73 |
| Erwinia amylovora T8 | 0.53 | OLJFJH_06105 | | methylenetetrahydrofolate reductase | 0.41 | OLJFJH_01275 | | acetolactate synthase small subunit | low | > 58 |
| Klebsiella michiganensis M5al | 0.53 | BWI76_RS00805 | | 5,10-methylenetetrahydrofolate reductase | 0.39 | BWI76_RS04700 | | acetolactate synthase small subunit | low | > 92 |
| Klebsiella pneumoniae MKP103 | 0.53 | KDGMDA_09325 | | methylenetetrahydrofolate reductase | 0.39 | KDGMDA_12930 | | acetolactate synthase small subunit | low | > 95 |
| Shewanella loihica PV-4 | 0.53 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.39 | Shew_1775 | | acetolactate synthase 3 regulatory subunit (RefSeq) | low | > 60 |
| Pantoea sp. MT58 | 0.53 | IAI47_00890 | | methylenetetrahydrofolate reductase | 0.40 | IAI47_15985 | | acetolactate synthase small subunit | low | > 76 |
| Pantoea agglomerans CFBP13505 P0401 | 0.53 | PagCFBP13505_RS18450 | | methylenetetrahydrofolate reductase | 0.40 | PagCFBP13505_RS13015 | | acetolactate synthase small subunit | low | > 74 |
| Serratia liquefaciens MT49 | 0.53 | IAI46_24530 | | methylenetetrahydrofolate reductase | 0.41 | IAI46_03380 | | acetolactate synthase small subunit | low | > 86 |
| Enterobacter asburiae PDN3 | 0.53 | EX28DRAFT_4413 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.40 | EX28DRAFT_3674 | | acetolactate synthase, small subunit (EC 2.2.1.6) | low | > 76 |
| Shewanella amazonensis SB2B | 0.53 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.39 | Sama_2019 | ilvH | acetolactate synthase 3 regulatory subunit (RefSeq) | low | > 62 |
| Escherichia fergusonii Becca | 0.53 | EFB2_04672 | | 5,10-methylenetetrahydrofolate reductase | 0.39 | EFB2_03968 | | Acetolactate synthase isozyme 3 small subunit | low | > 86 |
| Enterobacter sp. TBS_079 | 0.53 | MPMX20_04529 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | MPMX20_00772 | | Acetolactate synthase isozyme 3 small subunit | low | > 85 |
| Erwinia tracheiphila HP pepo 2.2 | 0.53 | IJEDHG_13030 | metF | methylenetetrahydrofolate reductase | 0.41 | IJEDHG_05985 | ilvN | acetolactate synthase small subunit | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.53 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | 0.41 | LU632_RS02890 | ilvN | acetolactate synthase small subunit | low | > 74 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.53 | OHPLBJKB_04109 | | 5,10-methylenetetrahydrofolate reductase | 0.39 | OHPLBJKB_03580 | | Acetolactate synthase isozyme 3 small subunit | low | > 74 |
| Escherichia coli ECRC102 | 0.53 | NIAGMN_11420 | metF | methylenetetrahydrofolate reductase | 0.39 | NIAGMN_08545 | ilvN | acetolactate synthase small subunit | low | > 80 |
| Escherichia coli ECOR38 | 0.53 | HEPCGN_12310 | metF | methylenetetrahydrofolate reductase | 0.40 | HEPCGN_08675 | ilvN | acetolactate synthase small subunit | low | > 88 |
| Escherichia coli ECRC98 | 0.53 | JDDGAC_17290 | metF | methylenetetrahydrofolate reductase | 0.39 | JDDGAC_14290 | ilvN | acetolactate synthase small subunit | low | > 87 |
| Escherichia coli ECRC99 | 0.53 | KEDOAH_14495 | metF | methylenetetrahydrofolate reductase | 0.39 | KEDOAH_17460 | ilvN | acetolactate synthase small subunit | — | — |
| Escherichia coli ECRC101 | 0.53 | MCAODC_04165 | metF | methylenetetrahydrofolate reductase | 0.39 | MCAODC_01210 | ilvN | acetolactate synthase small subunit | low | > 88 |
| Escherichia coli BL21 | 0.53 | ECD_03827 | | 5,10-methylenetetrahydrofolate reductase | 0.39 | ECD_00080 | | acetolactate synthase 3, small subunit, valine-sensitive | low | > 61 |
| Escherichia coli BW25113 | 0.53 | b3941 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.39 | b0078 | ilvH | acetolactate synthase small subunit (NCBI) | 0.78 | 75 |
| Escherichia coli Nissle 1917 | 0.53 | ECOLIN_RS22760 | | methylenetetrahydrofolate reductase | 0.39 | ECOLIN_RS00420 | | acetolactate synthase small subunit | low | > 55 |
| Escherichia coli ECRC62 | 0.53 | BNILDI_05725 | metF | methylenetetrahydrofolate reductase | 0.39 | BNILDI_08570 | ilvN | acetolactate synthase small subunit | low | > 75 |
| Escherichia coli ECOR27 | 0.53 | NOLOHH_05810 | metF | methylenetetrahydrofolate reductase | 0.39 | NOLOHH_03040 | ilvN | acetolactate synthase small subunit | low | > 76 |
| Escherichia coli ECRC100 | 0.53 | OKFHMN_13665 | metF | methylenetetrahydrofolate reductase | 0.39 | OKFHMN_10695 | ilvN | acetolactate synthase small subunit | low | > 79 |
| Vibrio cholerae E7946 ATCC 55056 | 0.52 | CSW01_13560 | | methylenetetrahydrofolate reductase | 0.38 | CSW01_12560 | | acetolactate synthase small subunit | low | > 62 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.52 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.39 | GFF160 | | Acetolactate synthase small subunit (EC 2.2.1.6) | low | > 78 |
| Caulobacter crescentus NA1000 | 0.52 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.52 | CCNA_02186 | | acetolactate synthase small subunit | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.52 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.52 | CCNA_02186 | | acetolactate synthase small subunit | low | > 67 |
| Rhodopseudomonas palustris CGA009 | 0.51 | TX73_019175 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.57 | TX73_010470 | | acetolactate synthase small subunit | low | > 86 |
| Alteromonas macleodii MIT1002 | 0.49 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | 0.43 | MIT1002_00504 | | Acetolactate synthase isozyme 3 small subunit | low | > 70 |
| Phaeobacter inhibens DSM 17395 | 0.46 | PGA1_c11700 | | 5,10-methylenetetrahydrofolate reductase MetF | 0.63 | PGA1_c20220 | | acetolactate synthase isozyme 3 small subunit | low | > 62 |
| Rhizobium sp. OAE497 | 0.46 | ABIE40_RS11950 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.54 | ABIE40_RS11490 | | acetolactate synthase small subunit | low | > 107 |
| Sinorhizobium meliloti 1021 | 0.44 | SMc01843 | | 5,10-methylenetetrahydrofolate reductase | 0.56 | SMc01430 | | acetolactate synthase 3 regulatory subunit | 0.86 | 63 |
| Agrobacterium fabrum C58 | 0.43 | Atu2123 | | methylenetetrahydrofolate reductase | 0.57 | Atu2035 | | acetolactate synthase, small subunit | low | > 89 |
| Dinoroseobacter shibae DFL-12 | 0.42 | Dshi_2080 | | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.61 | Dshi_1781 | | acetolactate synthase, small subunit (RefSeq) | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.36 | QEN71_RS28715 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.43 | QEN71_RS24220 | | acetolactate synthase small subunit | low | > 153 |
| Ralstonia solanacearum GMI1000 | 0.36 | RS_RS00460 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.42 | RS_RS10415 | | acetolactate synthase small subunit | low | > 80 |
| Cupriavidus basilensis FW507-4G11 | 0.36 | RR42_RS01385 | | 5,10-methylenetetrahydrofolate reductase | 0.42 | RR42_RS05440 | | acetolactate synthase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.35 | H281DRAFT_05801 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) | 0.42 | H281DRAFT_04552 | | acetolactate synthase, small subunit | low | > 103 |
| Ralstonia solanacearum UW163 | 0.35 | UW163_RS03705 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.42 | UW163_RS10680 | | acetolactate synthase small subunit | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.35 | RALBFv3_RS09875 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.42 | RALBFv3_RS03045 | | acetolactate synthase small subunit | low | > 76 |
| Ralstonia solanacearum PSI07 | 0.35 | RPSI07_RS23495 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.42 | RPSI07_RS14260 | | acetolactate synthase small subunit | low | > 81 |
| Ralstonia sp. UNC404CL21Col | 0.35 | ABZR87_RS04865 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.42 | ABZR87_RS14950 | | acetolactate synthase small subunit | 0.68 | 32 |
| Pseudomonas aeruginosa PA14 | 0.35 | IKLFDK_23270 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.40 | IKLFDK_30150 | | acetolactate synthase small subunit | — | — |
| Pseudomonas lactucae CFBP13502 | 0.35 | GEMAOFIL_05433 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | GEMAOFIL_04912 | | Acetolactate synthase isozyme 3 small subunit | low | > 93 |
| Paraburkholderia graminis OAS925 | 0.35 | ABIE53_000061 | | methylenetetrahydrofolate reductase (NADPH) | 0.43 | ABIE53_001575 | | acetolactate synthase-1/3 small subunit | low | > 113 |
| Pseudomonas fluorescens FW300-N2E2 | 0.34 | Pf6N2E2_4638 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.40 | Pf6N2E2_5176 | | Acetolactate synthase small subunit (EC 2.2.1.6) | 0.79 | 3 |
| Pseudomonas stutzeri RCH2 | 0.34 | Psest_0313 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.41 | Psest_1037 | | acetolactate synthase, small subunit | 0.79 | 26 |
| Pseudomonas fluorescens SBW25-INTG | 0.34 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.40 | PFLU_RS25645 | | acetolactate synthase small subunit | 0.48 | 32 |
| Pseudomonas fluorescens SBW25 | 0.34 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.40 | PFLU_RS25645 | | acetolactate synthase small subunit | low | > 109 |
| Pseudomonas fluorescens FW300-N1B4 | 0.34 | Pf1N1B4_2384 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.40 | Pf1N1B4_2879 | | Acetolactate synthase small subunit (EC 2.2.1.6) | 0.90 | 3 |
| Pseudomonas sp. DMC3 | 0.34 | GFF171 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | GFF4051 | | Acetolactate synthase isozyme 3 small subunit | 0.94 | 36 |
| Burkholderia phytofirmans PsJN | 0.34 | BPHYT_RS18705 | | 5,10-methylenetetrahydrofolate reductase | 0.42 | BPHYT_RS06550 | | acetolactate synthase | low | > 109 |
| Pseudomonas fluorescens FW300-N2E3 | 0.34 | AO353_08015 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | AO353_14500 | | acetolactate synthase 3 regulatory subunit | 0.90 | 2 |
| Dechlorosoma suillum PS | 0.34 | Dsui_0640 | | 5,10-methylenetetrahydrofolate reductase | 0.41 | Dsui_3528 | | acetolactate synthase, small subunit | — | — |
| Marinobacter adhaerens HP15 | 0.34 | HP15_2917 | | 5,10-methylenetetrahydrofolate reductase-like protein | 0.41 | HP15_532 | | acetolactate synthase 3 regulatory subunit | 0.79 | 27 |
| Pseudomonas fluorescens GW456-L13 | 0.34 | PfGW456L13_1050 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.40 | PfGW456L13_1539 | | Acetolactate synthase small subunit (EC 2.2.1.6) | 0.91 | 13 |
| Pseudomonas segetis P6 | 0.34 | MPMX49_00645 | | 5,10-methylenetetrahydrofolate reductase | 0.41 | MPMX49_01275 | | Acetolactate synthase isozyme 3 small subunit | low | > 75 |
| Pseudomonas putida KT2440 | 0.34 | PP_4977 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | PP_4679 | | acetohydroxybutanoate synthase / acetolactate synthase | 0.48 | 37 |
| Pseudomonas simiae WCS417 | 0.33 | PS417_26510 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | PS417_23805 | | acetolactate synthase 3 regulatory subunit | 0.41 | 44 |
| Pseudomonas sp. RS175 | 0.33 | PFR28_04202 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | PFR28_03698 | | Acetolactate synthase isozyme 3 small subunit | 0.67 | 10 |
| Pseudomonas fluorescens FW300-N2C3 | 0.33 | AO356_13605 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | AO356_16175 | | acetolactate synthase 3 regulatory subunit | 0.97 | 2 |
| Pseudomonas sp. BP01 | 0.33 | JOY50_RS09810 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.40 | JOY50_RS27765 | ilvN | acetolactate synthase small subunit | 0.92 | 39 |
| Pseudomonas sp. SVBP6 | 0.33 | COO64_RS17485 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.39 | COO64_RS15000 | ilvN | acetolactate synthase small subunit | 0.99 | 3 |
| Methylophilus sp. DMC18 | 0.33 | GFF1492 | | 5,10-methylenetetrahydrofolate reductase | 0.46 | GFF2520 | | Acetolactate synthase isozyme 3 small subunit | — | — |
| Pseudomonas sp. S08-1 | 0.33 | OH686_10820 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.40 | OH686_08125 | | acetolactate synthase, small subunit | 0.70 | 31 |
| Pseudomonas syringae pv. syringae B728a | 0.33 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | Psyr_0847 | | acetolactate synthase, small subunit | 0.68 | 6 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.33 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.40 | Psyr_0847 | | acetolactate synthase, small subunit | low | > 86 |
| Herbaspirillum seropedicae SmR1 | 0.32 | HSERO_RS21425 | | 5,10-methylenetetrahydrofolate reductase | 0.43 | HSERO_RS08655 | | acetolactate synthase | low | > 78 |
| Acidovorax sp. GW101-3H11 | 0.31 | Ac3H11_3045 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.42 | Ac3H11_526 | | Acetolactate synthase small subunit (EC 2.2.1.6) | 0.80 | 32 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.31 | GFF1692 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.41 | GFF4277 | | Acetolactate synthase small subunit (EC 2.2.1.6) | — | — |
| Castellaniella sp019104865 MT123 | 0.30 | ABCV34_RS13550 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.40 | ABCV34_RS01215 | | acetolactate synthase small subunit | low | > 48 |
| Acinetobacter baumannii LAC-4 | 0.30 | RR41_RS05725 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.43 | RR41_RS16330 | | acetolactate synthase small subunit | low | > 55 |
| Acinetobacter radioresistens SK82 | 0.30 | MPMX26_01002 | | 5,10-methylenetetrahydrofolate reductase | 0.43 | MPMX26_00473 | | Acetolactate synthase isozyme 3 small subunit | low | > 36 |
| Variovorax sp. SCN45 | 0.29 | GFF2055 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.43 | GFF1159 | | Acetolactate synthase small subunit (EC 2.2.1.6) | low | > 127 |
| Variovorax sp. OAS795 | 0.29 | ABID97_RS25015 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.42 | ABID97_RS14890 | | acetolactate synthase small subunit | low | > 91 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.27 | DVU0997 | metF | 5,10-methylenetetrahydrofolate reductase (TIGR) | 0.40 | DVU1377 | ilvN-2 | acetolactate synthase, small subunit (TIGR) | low | > 55 |
| Desulfovibrio vulgaris Miyazaki F | 0.26 | DvMF_3034 | | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.41 | DvMF_0154 | ilvH | acetolactate synthase 3 regulatory subunit (RefSeq) | — | — |
| Bifidobacterium breve UCC2003 | 0.24 | BBR_RS15410 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.37 | BBR_RS12345 | | acetolactate synthase small subunit | low | > 34 |
| Cellulophaga baltica 18 | 0.19 | M666_RS08215 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.16 | M666_RS14925 | | acetolactate synthase small subunit | low | > 67 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.19 | Echvi_3637 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.18 | Echvi_2057 | | acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) (from data) | 0.92 | 15 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.18 | CA264_16780 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.17 | CA264_06925 | | acetolactate synthase small subunit | low | > 74 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.17 | ABZR88_RS20935 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.20 | ABZR88_RS11585 | | acetolactate synthase small subunit | low | > 71 |
Not shown: 17 genomes with orthologs for GFF217 only; 5 genomes with orthologs for GFF2056 only