Conservation of cofitness between GFF217 and GFF2056 in Sphingobium sp. HT1-2

98 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF217 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 1.0 GFF2056 Acetolactate synthase small subunit (EC 2.2.1.6) 0.85 25
Sphingomonas koreensis DSMZ 15582 0.74 Ga0059261_0992 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.73 Ga0059261_0067 acetolactate synthase, small subunit (EC 2.2.1.6) 0.63 51
Rhodospirillum rubrum S1H 0.59 Rru_A1530 5,10-methylenetetrahydrofolate reductase (NCBI) 0.63 Rru_A0468 Acetolactate synthase, small subunit (NCBI) 0.87 22
Azospirillum brasilense Sp245 0.59 AZOBR_RS09540 5 10-methylenetetrahydrofolate reductase 0.65 AZOBR_RS06565 acetolactate synthase low > 97
Magnetospirillum magneticum AMB-1 0.58 AMB_RS02230 methylenetetrahydrofolate reductase 0.58 AMB_RS17745 acetolactate synthase small subunit
Xanthobacter sp. DMC5 0.57 GFF4147 5,10-methylenetetrahydrofolate reductase 0.59 GFF171 Acetolactate synthase small subunit
Azospirillum sp. SherDot2 0.56 MPMX19_00635 5,10-methylenetetrahydrofolate reductase 0.64 MPMX19_01775 Acetolactate synthase isozyme 3 small subunit
Pectobacterium carotovorum WPP14 0.55 HER17_RS00950 methylenetetrahydrofolate reductase 0.41 HER17_RS03100 acetolactate synthase small subunit low > 75
Dickeya dianthicola ME23 0.54 DZA65_RS21460 methylenetetrahydrofolate reductase 0.42 DZA65_RS19180 acetolactate synthase small subunit low > 75
Dickeya dianthicola 67-19 0.54 HGI48_RS20415 methylenetetrahydrofolate reductase 0.42 HGI48_RS18035 acetolactate synthase small subunit low > 71
Dickeya dadantii 3937 0.54 DDA3937_RS00960 methylenetetrahydrofolate reductase 0.42 DDA3937_RS18100 acetolactate synthase small subunit low > 74
Bosea sp. OAE506 0.54 ABIE41_RS12475 methylenetetrahydrofolate reductase [NAD(P)H] 0.58 ABIE41_RS12905 acetolactate synthase small subunit
Rahnella sp. WP5 0.54 EX31_RS14205 methylenetetrahydrofolate reductase 0.40 EX31_RS03660 acetolactate synthase small subunit low > 89
Shewanella oneidensis MR-1 0.54 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.42 SO2278 ilvH acetolactate synthase III, small subunit (NCBI ptt file)
Shewanella sp. ANA-3 0.54 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.42 Shewana3_2270 ilvH acetolactate synthase 3 regulatory subunit (RefSeq) low > 73
Erwinia amylovora T8 0.53 OLJFJH_06105 methylenetetrahydrofolate reductase 0.41 OLJFJH_01275 acetolactate synthase small subunit low > 58
Klebsiella michiganensis M5al 0.53 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 0.39 BWI76_RS04700 acetolactate synthase small subunit low > 92
Klebsiella pneumoniae MKP103 0.53 KDGMDA_09325 methylenetetrahydrofolate reductase 0.39 KDGMDA_12930 acetolactate synthase small subunit low > 95
Shewanella loihica PV-4 0.53 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.39 Shew_1775 acetolactate synthase 3 regulatory subunit (RefSeq) low > 60
Pantoea sp. MT58 0.53 IAI47_00890 methylenetetrahydrofolate reductase 0.40 IAI47_15985 acetolactate synthase small subunit low > 76
Pantoea agglomerans CFBP13505 P0401 0.53 PagCFBP13505_RS18450 methylenetetrahydrofolate reductase 0.40 PagCFBP13505_RS13015 acetolactate synthase small subunit low > 74
Serratia liquefaciens MT49 0.53 IAI46_24530 methylenetetrahydrofolate reductase 0.41 IAI46_03380 acetolactate synthase small subunit low > 86
Enterobacter asburiae PDN3 0.53 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.40 EX28DRAFT_3674 acetolactate synthase, small subunit (EC 2.2.1.6) low > 76
Shewanella amazonensis SB2B 0.53 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.39 Sama_2019 ilvH acetolactate synthase 3 regulatory subunit (RefSeq) low > 62
Escherichia fergusonii Becca 0.53 EFB2_04672 5,10-methylenetetrahydrofolate reductase 0.39 EFB2_03968 Acetolactate synthase isozyme 3 small subunit low > 86
Enterobacter sp. TBS_079 0.53 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.40 MPMX20_00772 Acetolactate synthase isozyme 3 small subunit low > 85
Erwinia tracheiphila HP pepo 2.2 0.53 IJEDHG_13030 metF methylenetetrahydrofolate reductase 0.41 IJEDHG_05985 ilvN acetolactate synthase small subunit low > 61
Erwinia tracheiphila SCR3 0.53 LU632_RS19630 metF methylenetetrahydrofolate reductase 0.41 LU632_RS02890 ilvN acetolactate synthase small subunit low > 74
Escherichia coli HS(pFamp)R (ATCC 700891) 0.53 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase 0.39 OHPLBJKB_03580 Acetolactate synthase isozyme 3 small subunit low > 74
Escherichia coli ECRC102 0.53 NIAGMN_11420 metF methylenetetrahydrofolate reductase 0.39 NIAGMN_08545 ilvN acetolactate synthase small subunit low > 80
Escherichia coli ECOR38 0.53 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.40 HEPCGN_08675 ilvN acetolactate synthase small subunit low > 88
Escherichia coli ECRC98 0.53 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.39 JDDGAC_14290 ilvN acetolactate synthase small subunit low > 87
Escherichia coli ECRC99 0.53 KEDOAH_14495 metF methylenetetrahydrofolate reductase 0.39 KEDOAH_17460 ilvN acetolactate synthase small subunit
Escherichia coli ECRC101 0.53 MCAODC_04165 metF methylenetetrahydrofolate reductase 0.39 MCAODC_01210 ilvN acetolactate synthase small subunit low > 88
Escherichia coli BL21 0.53 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.39 ECD_00080 acetolactate synthase 3, small subunit, valine-sensitive low > 61
Escherichia coli BW25113 0.53 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.39 b0078 ilvH acetolactate synthase small subunit (NCBI) 0.78 75
Escherichia coli Nissle 1917 0.53 ECOLIN_RS22760 methylenetetrahydrofolate reductase 0.39 ECOLIN_RS00420 acetolactate synthase small subunit low > 55
Escherichia coli ECRC62 0.53 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.39 BNILDI_08570 ilvN acetolactate synthase small subunit low > 75
Escherichia coli ECOR27 0.53 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.39 NOLOHH_03040 ilvN acetolactate synthase small subunit low > 76
Escherichia coli ECRC100 0.53 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.39 OKFHMN_10695 ilvN acetolactate synthase small subunit low > 79
Vibrio cholerae E7946 ATCC 55056 0.52 CSW01_13560 methylenetetrahydrofolate reductase 0.38 CSW01_12560 acetolactate synthase small subunit low > 62
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.52 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.39 GFF160 Acetolactate synthase small subunit (EC 2.2.1.6) low > 78
Caulobacter crescentus NA1000 0.52 CCNA_02224 methylenetetrahydrofolate reductase 0.52 CCNA_02186 acetolactate synthase small subunit low > 66
Caulobacter crescentus NA1000 Δfur 0.52 CCNA_02224 methylenetetrahydrofolate reductase 0.52 CCNA_02186 acetolactate synthase small subunit low > 67
Rhodopseudomonas palustris CGA009 0.51 TX73_019175 methylenetetrahydrofolate reductase [NAD(P)H] 0.57 TX73_010470 acetolactate synthase small subunit low > 86
Alteromonas macleodii MIT1002 0.49 MIT1002_03670 5,10-methylenetetrahydrofolate reductase 0.43 MIT1002_00504 Acetolactate synthase isozyme 3 small subunit low > 70
Phaeobacter inhibens DSM 17395 0.46 PGA1_c11700 5,10-methylenetetrahydrofolate reductase MetF 0.63 PGA1_c20220 acetolactate synthase isozyme 3 small subunit low > 62
Rhizobium sp. OAE497 0.46 ABIE40_RS11950 methylenetetrahydrofolate reductase [NAD(P)H] 0.54 ABIE40_RS11490 acetolactate synthase small subunit low > 107
Sinorhizobium meliloti 1021 0.44 SMc01843 5,10-methylenetetrahydrofolate reductase 0.56 SMc01430 acetolactate synthase 3 regulatory subunit 0.86 63
Agrobacterium fabrum C58 0.43 Atu2123 methylenetetrahydrofolate reductase 0.57 Atu2035 acetolactate synthase, small subunit low > 89
Dinoroseobacter shibae DFL-12 0.42 Dshi_2080 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.61 Dshi_1781 acetolactate synthase, small subunit (RefSeq)
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS28715 methylenetetrahydrofolate reductase [NAD(P)H] 0.43 QEN71_RS24220 acetolactate synthase small subunit low > 153
Ralstonia solanacearum GMI1000 0.36 RS_RS00460 methylenetetrahydrofolate reductase [NAD(P)H] 0.42 RS_RS10415 acetolactate synthase small subunit low > 80
Cupriavidus basilensis FW507-4G11 0.36 RR42_RS01385 5,10-methylenetetrahydrofolate reductase 0.42 RR42_RS05440 acetolactate synthase
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_05801 5,10-methylenetetrahydrofolate reductase (NAD(P)) 0.42 H281DRAFT_04552 acetolactate synthase, small subunit low > 103
Ralstonia solanacearum UW163 0.35 UW163_RS03705 methylenetetrahydrofolate reductase [NAD(P)H] 0.42 UW163_RS10680 acetolactate synthase small subunit
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS09875 methylenetetrahydrofolate reductase [NAD(P)H] 0.42 RALBFv3_RS03045 acetolactate synthase small subunit low > 76
Ralstonia solanacearum PSI07 0.35 RPSI07_RS23495 methylenetetrahydrofolate reductase [NAD(P)H] 0.42 RPSI07_RS14260 acetolactate synthase small subunit low > 81
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS04865 methylenetetrahydrofolate reductase [NAD(P)H] 0.42 ABZR87_RS14950 acetolactate synthase small subunit 0.68 32
Pseudomonas aeruginosa PA14 0.35 IKLFDK_23270 methylenetetrahydrofolate reductase [NAD(P)H] 0.40 IKLFDK_30150 acetolactate synthase small subunit
Pseudomonas lactucae CFBP13502 0.35 GEMAOFIL_05433 5,10-methylenetetrahydrofolate reductase 0.40 GEMAOFIL_04912 Acetolactate synthase isozyme 3 small subunit low > 93
Paraburkholderia graminis OAS925 0.35 ABIE53_000061 methylenetetrahydrofolate reductase (NADPH) 0.43 ABIE53_001575 acetolactate synthase-1/3 small subunit low > 113
Pseudomonas fluorescens FW300-N2E2 0.34 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.40 Pf6N2E2_5176 Acetolactate synthase small subunit (EC 2.2.1.6) 0.79 3
Pseudomonas stutzeri RCH2 0.34 Psest_0313 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.41 Psest_1037 acetolactate synthase, small subunit 0.79 26
Pseudomonas fluorescens SBW25-INTG 0.34 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.40 PFLU_RS25645 acetolactate synthase small subunit 0.48 32
Pseudomonas fluorescens SBW25 0.34 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.40 PFLU_RS25645 acetolactate synthase small subunit low > 109
Pseudomonas fluorescens FW300-N1B4 0.34 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.40 Pf1N1B4_2879 Acetolactate synthase small subunit (EC 2.2.1.6) 0.90 3
Pseudomonas sp. DMC3 0.34 GFF171 5,10-methylenetetrahydrofolate reductase 0.40 GFF4051 Acetolactate synthase isozyme 3 small subunit 0.94 36
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS18705 5,10-methylenetetrahydrofolate reductase 0.42 BPHYT_RS06550 acetolactate synthase low > 109
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_08015 5,10-methylenetetrahydrofolate reductase 0.40 AO353_14500 acetolactate synthase 3 regulatory subunit 0.90 2
Dechlorosoma suillum PS 0.34 Dsui_0640 5,10-methylenetetrahydrofolate reductase 0.41 Dsui_3528 acetolactate synthase, small subunit
Marinobacter adhaerens HP15 0.34 HP15_2917 5,10-methylenetetrahydrofolate reductase-like protein 0.41 HP15_532 acetolactate synthase 3 regulatory subunit 0.79 27
Pseudomonas fluorescens GW456-L13 0.34 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.40 PfGW456L13_1539 Acetolactate synthase small subunit (EC 2.2.1.6) 0.91 13
Pseudomonas segetis P6 0.34 MPMX49_00645 5,10-methylenetetrahydrofolate reductase 0.41 MPMX49_01275 Acetolactate synthase isozyme 3 small subunit low > 75
Pseudomonas putida KT2440 0.34 PP_4977 5,10-methylenetetrahydrofolate reductase 0.40 PP_4679 acetohydroxybutanoate synthase / acetolactate synthase 0.48 37
Pseudomonas simiae WCS417 0.33 PS417_26510 5,10-methylenetetrahydrofolate reductase 0.40 PS417_23805 acetolactate synthase 3 regulatory subunit 0.41 44
Pseudomonas sp. RS175 0.33 PFR28_04202 5,10-methylenetetrahydrofolate reductase 0.40 PFR28_03698 Acetolactate synthase isozyme 3 small subunit 0.67 10
Pseudomonas fluorescens FW300-N2C3 0.33 AO356_13605 5,10-methylenetetrahydrofolate reductase 0.40 AO356_16175 acetolactate synthase 3 regulatory subunit 0.97 2
Pseudomonas sp. BP01 0.33 JOY50_RS09810 metF methylenetetrahydrofolate reductase [NAD(P)H] 0.40 JOY50_RS27765 ilvN acetolactate synthase small subunit 0.92 39
Pseudomonas sp. SVBP6 0.33 COO64_RS17485 metF methylenetetrahydrofolate reductase [NAD(P)H] 0.39 COO64_RS15000 ilvN acetolactate synthase small subunit 0.99 3
Methylophilus sp. DMC18 0.33 GFF1492 5,10-methylenetetrahydrofolate reductase 0.46 GFF2520 Acetolactate synthase isozyme 3 small subunit
Pseudomonas sp. S08-1 0.33 OH686_10820 methylenetetrahydrofolate reductase [NAD(P)H] 0.40 OH686_08125 acetolactate synthase, small subunit 0.70 31
Pseudomonas syringae pv. syringae B728a 0.33 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.40 Psyr_0847 acetolactate synthase, small subunit 0.68 6
Pseudomonas syringae pv. syringae B728a ΔmexB 0.33 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.40 Psyr_0847 acetolactate synthase, small subunit low > 86
Herbaspirillum seropedicae SmR1 0.32 HSERO_RS21425 5,10-methylenetetrahydrofolate reductase 0.43 HSERO_RS08655 acetolactate synthase low > 78
Acidovorax sp. GW101-3H11 0.31 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.42 Ac3H11_526 Acetolactate synthase small subunit (EC 2.2.1.6) 0.80 32
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF1692 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.41 GFF4277 Acetolactate synthase small subunit (EC 2.2.1.6)
Castellaniella sp019104865 MT123 0.30 ABCV34_RS13550 methylenetetrahydrofolate reductase [NAD(P)H] 0.40 ABCV34_RS01215 acetolactate synthase small subunit low > 48
Acinetobacter baumannii LAC-4 0.30 RR41_RS05725 methylenetetrahydrofolate reductase [NAD(P)H] 0.43 RR41_RS16330 acetolactate synthase small subunit low > 55
Acinetobacter radioresistens SK82 0.30 MPMX26_01002 5,10-methylenetetrahydrofolate reductase 0.43 MPMX26_00473 Acetolactate synthase isozyme 3 small subunit low > 36
Variovorax sp. SCN45 0.29 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.43 GFF1159 Acetolactate synthase small subunit (EC 2.2.1.6) low > 127
Variovorax sp. OAS795 0.29 ABID97_RS25015 methylenetetrahydrofolate reductase [NAD(P)H] 0.42 ABID97_RS14890 acetolactate synthase small subunit low > 91
Desulfovibrio vulgaris Hildenborough JW710 0.27 DVU0997 metF 5,10-methylenetetrahydrofolate reductase (TIGR) 0.40 DVU1377 ilvN-2 acetolactate synthase, small subunit (TIGR) low > 55
Desulfovibrio vulgaris Miyazaki F 0.26 DvMF_3034 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.41 DvMF_0154 ilvH acetolactate synthase 3 regulatory subunit (RefSeq)
Bifidobacterium breve UCC2003 0.24 BBR_RS15410 methylenetetrahydrofolate reductase [NAD(P)H] 0.37 BBR_RS12345 acetolactate synthase small subunit low > 34
Cellulophaga baltica 18 0.19 M666_RS08215 methylenetetrahydrofolate reductase [NAD(P)H] 0.16 M666_RS14925 acetolactate synthase small subunit low > 67
Echinicola vietnamensis KMM 6221, DSM 17526 0.19 Echvi_3637 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.18 Echvi_2057 acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) (from data) 0.92 15
Pontibacter actiniarum KMM 6156, DSM 19842 0.18 CA264_16780 methylenetetrahydrofolate reductase [NAD(P)H] 0.17 CA264_06925 acetolactate synthase small subunit low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.17 ABZR88_RS20935 methylenetetrahydrofolate reductase [NAD(P)H] 0.20 ABZR88_RS11585 acetolactate synthase small subunit low > 71

Not shown: 17 genomes with orthologs for GFF217 only; 5 genomes with orthologs for GFF2056 only