Conservation of cofitness between CSW01_01015 and CSW01_04845 in Vibrio cholerae E7946 ATCC 55056

92 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01015 DNA helicase II 1.0 CSW01_04845 D-alanyl-D-alanine carboxypeptidase 0.73 14
Escherichia coli BW25113 0.71 b3813 uvrD DNA-dependent ATPase I and helicase II (NCBI) 0.55 b0632 dacA D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) low > 76
Escherichia coli ECOR27 0.71 NOLOHH_06540 uvrD DNA helicase II 0.55 NOLOHH_23755 dacA D-alanyl-D-alanine carboxypeptidase DacA low > 76
Escherichia coli ECRC62 0.71 BNILDI_04995 uvrD DNA helicase II 0.55 BNILDI_21765 dacA D-alanyl-D-alanine carboxypeptidase DacA low > 75
Escherichia coli BL21 0.71 ECD_03689 DNA-dependent ATPase I and helicase II 0.55 ECD_00601 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) — —
Escherichia coli ECRC101 0.71 MCAODC_04915 uvrD DNA helicase II 0.55 MCAODC_26595 dacA D-alanyl-D-alanine carboxypeptidase DacA low > 87
Escherichia coli ECRC102 0.71 NIAGMN_12165 uvrD DNA helicase II 0.55 NIAGMN_05435 dacA D-alanyl-D-alanine carboxypeptidase DacA low > 80
Escherichia coli HS(pFamp)R (ATCC 700891) 0.71 OHPLBJKB_04237 DNA helicase II 0.55 OHPLBJKB_03074 D-alanyl-D-alanine carboxypeptidase DacA 0.59 26
Escherichia coli ECRC100 0.71 OKFHMN_14410 uvrD DNA helicase II 0.55 OKFHMN_07380 dacA D-alanyl-D-alanine carboxypeptidase DacA low > 79
Escherichia coli ECRC98 0.71 JDDGAC_18035 uvrD DNA helicase II 0.55 JDDGAC_11025 dacA D-alanyl-D-alanine carboxypeptidase DacA low > 87
Escherichia coli Nissle 1917 0.71 ECOLIN_RS21885 DNA helicase II 0.55 ECOLIN_RS03445 D-alanyl-D-alanine carboxypeptidase DacA — —
Escherichia fergusonii Becca 0.71 EFB2_04824 DNA helicase II 0.54 EFB2_03460 D-alanyl-D-alanine carboxypeptidase DacA low > 86
Escherichia coli ECRC99 0.71 KEDOAH_13740 uvrD DNA helicase II 0.55 KEDOAH_20590 dacA D-alanyl-D-alanine carboxypeptidase DacA — —
Klebsiella michiganensis M5al 0.71 BWI76_RS01220 DNA-dependent helicase II 0.55 BWI76_RS08020 serine-type D-Ala-D-Ala carboxypeptidase low > 92
Escherichia coli ECOR38 0.71 HEPCGN_13115 uvrD DNA helicase II 0.55 HEPCGN_00895 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.52 86
Serratia liquefaciens MT49 0.71 IAI46_00735 DNA helicase II 0.56 IAI46_05915 D-alanyl-D-alanine carboxypeptidase DacA low > 87
Klebsiella pneumoniae MKP103 0.71 KDGMDA_09710 DNA helicase II 0.55 KDGMDA_16380 D-alanyl-D-alanine carboxypeptidase DacA 0.67 9
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.71 GFF241 ATP-dependent DNA helicase UvrD/PcrA 0.55 GFF4545 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) low > 78
Enterobacter sp. TBS_079 0.70 MPMX20_04463 DNA helicase II 0.55 MPMX20_01291 D-alanyl-D-alanine carboxypeptidase DacA low > 85
Enterobacter asburiae PDN3 0.70 EX28DRAFT_4482 ATP-dependent DNA helicase UvrD (EC 3.6.1.-) 0.55 EX28DRAFT_2331 D-alanyl-D-alanine carboxypeptidase 0.47 60
Dickeya dadantii 3937 0.70 DDA3937_RS19880 DNA helicase II 0.57 DDA3937_RS06155 D-alanyl-D-alanine carboxypeptidase DacA low > 74
Dickeya dianthicola 67-19 0.70 HGI48_RS20035 DNA helicase II 0.57 HGI48_RS06200 D-alanyl-D-alanine carboxypeptidase DacA low > 71
Dickeya dianthicola ME23 0.70 DZA65_RS21080 DNA helicase II 0.56 DZA65_RS06545 D-alanyl-D-alanine carboxypeptidase DacA low > 75
Pectobacterium carotovorum WPP14 0.70 HER17_RS01360 DNA helicase II 0.58 HER17_RS15260 D-alanyl-D-alanine carboxypeptidase DacA low > 75
Pantoea sp. MT58 0.69 IAI47_18390 DNA helicase II 0.57 IAI47_14040 D-alanyl-D-alanine carboxypeptidase DacA low > 76
Erwinia tracheiphila SCR3 0.68 LU632_RS24125 uvrD DNA helicase II 0.56 LU632_RS16390 dacA D-alanyl-D-alanine carboxypeptidase DacA — —
Pantoea agglomerans CFBP13505 P0401 0.68 PagCFBP13505_RS15370 DNA helicase II 0.56 PagCFBP13505_RS03265 D-alanyl-D-alanine carboxypeptidase DacA low > 74
Erwinia tracheiphila HP pepo 2.2 0.68 IJEDHG_08770 uvrD DNA helicase II 0.56 IJEDHG_02480 D-alanyl-D-alanine carboxypeptidase DacC — —
Rahnella sp. WP5 0.68 EX31_RS15175 DNA helicase II 0.57 EX31_RS23105 D-alanyl-D-alanine carboxypeptidase DacA low > 89
Erwinia amylovora T8 0.68 OLJFJH_06425 DNA helicase II 0.55 OLJFJH_17245 D-alanyl-D-alanine carboxypeptidase DacA low > 58
Shewanella sp. ANA-3 0.67 Shewana3_0469 uvrD DNA-dependent helicase II (RefSeq) 0.69 Shewana3_0991 penicillin-binding protein 6 (RefSeq) 0.52 44
Shewanella oneidensis MR-1 0.67 SO0467 uvrD DNA helicase II (NCBI ptt file) 0.69 SO1164 dacA-1 D-alanyl-D-alanine carboxypeptidase (NCBI ptt file) — —
Shewanella loihica PV-4 0.66 Shew_3385 uvrD DNA-dependent helicase II (RefSeq) 0.68 Shew_2939 Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.66 Sama_0419 uvrD DNA-dependent helicase II (RefSeq) 0.69 Sama_2592 Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) — —
Alteromonas macleodii MIT1002 0.65 MIT1002_00153 DNA helicase II 0.62 MIT1002_01848 D-alanyl-D-alanine carboxypeptidase DacC precursor — —
Pseudomonas aeruginosa PUPa3 0.60 DQ20_RS57955 uvrD;go_function=DNA DNA helicase II 0.45 DQ20_RS48190 D-alanyl-D-alanine carboxypeptidase family protein low > 101
Pseudomonas aeruginosa PA14 0.60 IKLFDK_26200 DNA helicase II 0.45 IKLFDK_20625 serine-type D-Ala-D-Ala carboxypeptidase low > 98
Pseudomonas aeruginosa MRSN321 0.60 DY961_RS25505 uvrD;go_function=DNA DNA helicase II 0.45 DY961_RS12860 D-alanyl-D-alanine carboxypeptidase family protein low > 100
Pseudomonas putida KT2440 0.60 PP_5352 DNA-dependent ATPase I and helicase II, nucleotide Excision Repair Complex 0.45 PP_4803 D-alanyl-D-alanine carboxypeptidase low > 96
Pseudomonas sp. BP01 0.60 JOY50_RS08735 uvrD DNA helicase II 0.45 JOY50_RS17720 D-alanyl-D-alanine carboxypeptidase family protein 0.36 29
Pseudomonas sp. SVBP6 0.60 COO64_RS01845 uvrD DNA helicase II 0.46 COO64_RS15590 D-alanyl-D-alanine carboxypeptidase family protein low > 93
Pseudomonas fluorescens SBW25 0.59 PFLU_RS29900 DNA helicase II 0.46 PFLU_RS26635 D-alanyl-D-alanine carboxypeptidase 0.60 69
Pseudomonas orientalis W4I3 0.59 QF045_RS02600 DNA helicase II 0.46 QF045_RS26990 D-alanyl-D-alanine carboxypeptidase family protein — —
Pseudomonas fluorescens SBW25-INTG 0.59 PFLU_RS29900 DNA helicase II 0.46 PFLU_RS26635 D-alanyl-D-alanine carboxypeptidase 0.34 50
Pseudomonas lactucae CFBP13502 0.59 GEMAOFIL_00116 DNA helicase II 0.46 GEMAOFIL_05094 D-alanyl-D-alanine carboxypeptidase DacC low > 96
Pseudomonas sp. DMC3 0.59 GFF512 DNA helicase II 0.46 GFF3884 D-alanyl-D-alanine carboxypeptidase DacC low > 89
Pseudomonas fluorescens FW300-N2E3 0.59 AO353_10055 DNA helicase II 0.46 AO353_06455 D-alanyl-D-alanine carboxypeptidase 0.35 59
Pseudomonas sp. S08-1 0.59 OH686_13045 ATP-dependent DNA helicase UvrD/PcrA 0.45 OH686_09300 D-alanyl-D-alanine carboxypeptidase low > 80
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_724 ATP-dependent DNA helicase UvrD/PcrA 0.46 PfGW456L13_1364 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) — —
Pseudomonas stutzeri RCH2 0.59 Psest_4098 Superfamily I DNA and RNA helicases 0.46 Psest_0516 D-alanyl-D-alanine carboxypeptidase low > 67
Pseudomonas fluorescens FW300-N1B4 0.59 Pf1N1B4_2005 ATP-dependent DNA helicase UvrD/PcrA 0.46 Pf1N1B4_2696 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) — —
Pseudomonas fluorescens FW300-N2E2 0.59 Pf6N2E2_4273 ATP-dependent DNA helicase UvrD/PcrA 0.46 Pf6N2E2_5001 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) 0.33 41
Pseudomonas sp. RS175 0.59 PFR28_04523 DNA helicase II 0.47 PFR28_03864 D-alanyl-D-alanine carboxypeptidase DacC low > 88
Pseudomonas fluorescens FW300-N2C3 0.59 AO356_11990 DNA helicase II 0.46 AO356_15330 D-alanyl-D-alanine carboxypeptidase 0.39 29
Kangiella aquimarina DSM 16071 0.58 B158DRAFT_0238 Superfamily I DNA and RNA helicases 0.50 B158DRAFT_0079 D-alanyl-D-alanine carboxypeptidase — —
Pseudomonas segetis P6 0.58 ACVTMO_RS00885 uvrD DNA helicase II 0.46 ACVTMO_RS05235 D-alanyl-D-alanine carboxypeptidase family protein low > 75
Pseudomonas syringae pv. syringae B728a 0.58 Psyr_5065 ATP-dependent DNA helicase UvrD 0.47 Psyr_4361 penicillin-binding protein 6, Serine peptidase, MEROPS family S11 low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.58 Psyr_5065 ATP-dependent DNA helicase UvrD 0.47 Psyr_4361 penicillin-binding protein 6, Serine peptidase, MEROPS family S11 low > 86
Marinobacter adhaerens HP15 0.56 HP15_3403 UvrD/REP helicase 0.45 HP15_608 serine-type D-Ala-D-Ala carboxypeptidase — —
Rhodanobacter sp. FW510-T8 0.55 OKGIIK_16775 DNA helicase 0.42 OKGIIK_00090 serine-type D-Ala-D-Ala carboxypeptidase low > 53
Dyella japonica UNC79MFTsu3.2 0.55 ABZR86_RS16965 DNA helicase II 0.41 ABZR86_RS17490 D-alanyl-D-alanine carboxypeptidase family protein — —
Lysobacter sp. OAE881 0.55 ABIE51_RS01985 DNA helicase II 0.40 ABIE51_RS03165 D-alanyl-D-alanine carboxypeptidase family protein low > 62
Xanthomonas campestris pv. campestris strain 8004 0.54 Xcc-8004.5114.1 ATP-dependent DNA helicase UvrD/PcrA 0.42 Xcc-8004.907.1 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) low > 74
Rhodanobacter denitrificans MT42 0.54 LRK55_RS06595 DNA helicase II 0.41 LRK55_RS06235 D-alanyl-D-alanine carboxypeptidase family protein — —
Rhodanobacter denitrificans FW104-10B01 0.54 LRK54_RS06850 DNA helicase II 0.41 LRK54_RS06490 D-alanyl-D-alanine carboxypeptidase low > 59
Rhodanobacter sp000427505 FW510-R12 0.53 LRK53_RS01560 UvrD-helicase domain-containing protein 0.41 LRK53_RS17780 D-alanyl-D-alanine carboxypeptidase — —
Methylophilus sp. DMC18 0.48 GFF1664 DNA helicase II 0.39 GFF2179 D-alanyl-D-alanine carboxypeptidase DacC low > 43
Burkholderia phytofirmans PsJN 0.45 BPHYT_RS13840 DNA-dependent helicase 0.37 BPHYT_RS02415 cytochrome C550 — —
Dechlorosoma suillum PS 0.45 Dsui_1227 DNA/RNA helicase, superfamily I 0.37 Dsui_0899 D-alanyl-D-alanine carboxypeptidase low > 51
Paraburkholderia graminis OAS925 0.45 ABIE53_002936 DNA helicase-2/ATP-dependent DNA helicase PcrA 0.36 ABIE53_000626 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) — —
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_04469 ATP-dependent DNA helicase UvrD 0.36 H281DRAFT_02054 penicillin-binding protein 6. Serine peptidase. MEROPS family S11 — —
Paraburkholderia sabiae LMG 24235 0.44 QEN71_RS05110 3'-5' exonuclease 0.36 QEN71_RS01300 D-alanyl-D-alanine carboxypeptidase family protein — —
Acidovorax sp. GW101-3H11 0.44 Ac3H11_1660 ATP-dependent DNA helicase UvrD/PcrA 0.32 Ac3H11_2142 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) — —
Cupriavidus basilensis FW507-4G11 0.44 RR42_RS15090 DNA helicase 0.39 RR42_RS01680 cytochrome C550 low > 128
Variovorax sp. OAS795 0.44 ABID97_RS09150 UvrD-helicase domain-containing protein 0.32 ABID97_RS00695 D-alanyl-D-alanine carboxypeptidase family protein low > 91
Herbaspirillum seropedicae SmR1 0.43 HSERO_RS02160 DNA-dependent helicase 0.35 HSERO_RS21530 cytochrome C550 low > 78
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS15705 UvrD-helicase domain-containing protein 0.36 ABZR87_RS06610 D-alanyl-D-alanine carboxypeptidase family protein low > 80
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF5598 ATP-dependent DNA helicase UvrD/PcrA 0.33 GFF1806 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) — —
Ralstonia solanacearum UW163 0.42 UW163_RS09895 DNA-dependent helicase 0.34 UW163_RS02810 D-alanyl-D-alanine carboxypeptidase — —
Ralstonia solanacearum GMI1000 0.42 RS_RS11220 DNA-dependent helicase 0.35 RS_RS01610 D-alanyl-D-alanine carboxypeptidase low > 80
Ralstonia solanacearum IBSBF1503 0.42 RALBFv3_RS03775 DNA-dependent helicase 0.34 RALBFv3_RS10770 D-alanyl-D-alanine carboxypeptidase — —
Ralstonia solanacearum PSI07 0.42 RPSI07_RS13455 DNA-dependent helicase 0.36 RPSI07_RS22545 D-alanyl-D-alanine carboxypeptidase — —
Castellaniella sp019104865 MT123 0.42 ABCV34_RS05210 UvrD-helicase domain-containing protein 0.34 ABCV34_RS13340 D-alanyl-D-alanine carboxypeptidase family protein low > 48
Sphingobium sp. HT1-2 0.36 GFF1640 ATP-dependent DNA helicase UvrD/PcrA (EC 3.6.4.12) 0.29 GFF5300 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) — —
Azospirillum brasilense Sp245 0.35 AZOBR_RS12445 DNA helicase II 0.33 AZOBR_RS08775 D-alanyl-D-alanine carboxypeptidase — —
Bosea sp. OAE506 0.35 ABIE41_RS12730 UvrD-helicase domain-containing protein 0.30 ABIE41_RS15965 D-alanyl-D-alanine carboxypeptidase family protein — —
Sphingomonas koreensis DSMZ 15582 0.35 Ga0059261_0249 Superfamily I DNA and RNA helicases 0.28 Ga0059261_0122 D-alanyl-D-alanine carboxypeptidase — —
Phaeobacter inhibens DSM 17395 0.34 PGA1_c09450 DNA helicase II UvrD 0.26 PGA1_c08020 D-alanyl-D-alanine carboxypeptidase DacC — —
Azospirillum sp. SherDot2 0.34 MPMX19_01610 ATP-dependent DNA helicase PcrA 0.35 MPMX19_01465 D-alanyl-D-alanine carboxypeptidase DacC — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS03725 DNA helicase II 0.30 AMB_RS12315 D-alanyl-D-alanine carboxypeptidase low > 64
Dinoroseobacter shibae DFL-12 0.33 Dshi_2483 UvrD/REP helicase (RefSeq) 0.25 Dshi_0923 Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) — —
Rhodospirillum rubrum S1H 0.32 Rru_A1536 UvrD/REP helicase (NCBI) 0.38 Rru_A1704 Serine-type D-Ala-D-Ala carboxypeptidase (NCBI) — —
Sinorhizobium meliloti 1021 0.31 SMc01461 DNA helicase II protein 0.22 SMc01188 penicillin-binding precursor (D-alanyl-D-alanine carboxypeptidase fraction A) transmembrane protein — —

Not shown: 20 genomes with orthologs for CSW01_01015 only; 6 genomes with orthologs for CSW01_04845 only