Conservation of cofitness between CSW01_04820 and CSW01_03980 in Vibrio cholerae E7946 ATCC 55056

98 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_04820 serine hydroxymethyltransferase 1.0 CSW01_03980 IMP dehydrogenase 0.90 8
Shewanella sp. ANA-3 0.83 Shewana3_1094 glyA serine hydroxymethyltransferase (RefSeq) 0.78 Shewana3_1235 inosine 5'-monophosphate dehydrogenase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.83 SO3471 glyA serine hydroxymethyltransferase (NCBI ptt file) 0.77 SO3293 guaB inosine-5'-monophosphate dehydrogenase (NCBI ptt file) 0.83 76
Shewanella amazonensis SB2B 0.82 Sama_1014 glyA serine hydroxymethyltransferase (RefSeq) 0.77 Sama_2359 inosine 5'-monophosphate dehydrogenase (RefSeq) — —
Dickeya dadantii 3937 0.81 DDA3937_RS15600 serine hydroxymethyltransferase 0.76 DDA3937_RS15420 IMP dehydrogenase — —
Shewanella loihica PV-4 0.81 Shew_1185 glyA serine hydroxymethyltransferase (RefSeq) 0.76 Shew_1297 inositol-5-monophosphate dehydrogenase (RefSeq) — —
Dickeya dianthicola ME23 0.81 DZA65_RS16775 serine hydroxymethyltransferase 0.76 DZA65_RS16610 IMP dehydrogenase — —
Dickeya dianthicola 67-19 0.81 HGI48_RS15700 serine hydroxymethyltransferase 0.76 HGI48_RS15535 IMP dehydrogenase — —
Serratia liquefaciens MT49 0.81 IAI46_19395 serine hydroxymethyltransferase 0.77 IAI46_19210 IMP dehydrogenase — —
Pantoea agglomerans CFBP13505 P0401 0.81 PagCFBP13505_RS14850 serine hydroxymethyltransferase 0.77 PagCFBP13505_RS14995 IMP dehydrogenase — —
Pantoea sp. MT58 0.81 IAI47_04960 serine hydroxymethyltransferase 0.77 IAI47_05105 IMP dehydrogenase — —
Pectobacterium carotovorum WPP14 0.81 HER17_RS05950 serine hydroxymethyltransferase 0.77 HER17_RS06155 IMP dehydrogenase — —
Rahnella sp. WP5 0.80 EX31_RS20585 serine hydroxymethyltransferase 0.76 EX31_RS20450 IMP dehydrogenase — —
Erwinia tracheiphila SCR3 0.80 LU632_RS17915 serine hydroxymethyltransferase 0.76 LU632_RS17755 guaB IMP dehydrogenase — —
Erwinia tracheiphila HP pepo 2.2 0.80 IJEDHG_02915 Serine hydroxymethyltransferase 1 0.76 IJEDHG_02725 guaB IMP dehydrogenase — —
Erwinia amylovora T8 0.79 OLJFJH_10340 Serine hydroxymethyltransferase 0.73 OLJFJH_10500 IMP dehydrogenase — —
Escherichia coli ECRC100 0.79 OKFHMN_21510 glyA serine hydroxymethyltransferase 0.75 OKFHMN_21760 guaB IMP dehydrogenase low > 79
Escherichia coli ECOR27 0.79 NOLOHH_13185 glyA serine hydroxymethyltransferase 0.75 NOLOHH_13410 guaB IMP dehydrogenase low > 76
Escherichia coli ECRC62 0.79 BNILDI_11985 glyA serine hydroxymethyltransferase 0.75 BNILDI_12210 guaB IMP dehydrogenase 0.85 12
Escherichia coli ECRC98 0.79 JDDGAC_25175 glyA serine hydroxymethyltransferase 0.75 JDDGAC_25435 guaB IMP dehydrogenase — —
Escherichia coli BL21 0.79 ECD_02443 serine hydroxymethyltransferase 0.75 ECD_02400 IMP dehydrogenase low > 61
Escherichia coli ECRC102 0.79 NIAGMN_19280 glyA serine hydroxymethyltransferase 0.75 NIAGMN_19530 guaB IMP dehydrogenase low > 80
Escherichia fergusonii Becca 0.79 EFB2_01345 Serine hydroxymethyltransferase 0.75 EFB2_01385 Inosine-5'-monophosphate dehydrogenase — —
Escherichia coli ECOR38 0.79 HEPCGN_20655 glyA serine hydroxymethyltransferase 0.75 HEPCGN_20900 guaB IMP dehydrogenase low > 88
Escherichia coli ECRC101 0.79 MCAODC_12040 glyA serine hydroxymethyltransferase 0.75 MCAODC_12290 guaB IMP dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.79 OHPLBJKB_01156 Serine hydroxymethyltransferase 0.75 OHPLBJKB_01201 'Inosine-5'-monophosphate dehydrogenase' transl_table=11 low > 74
Escherichia coli BW25113 0.79 b2551 glyA serine hydroxymethyltransferase (NCBI) 0.75 b2508 guaB inositol-5-monophosphate dehydrogenase (NCBI) — —
Escherichia coli ECRC99 0.79 KEDOAH_06710 glyA serine hydroxymethyltransferase 0.75 KEDOAH_06460 guaB IMP dehydrogenase — —
Escherichia coli Nissle 1917 0.79 ECOLIN_RS14440 serine hydroxymethyltransferase 0.75 ECOLIN_RS14240 IMP dehydrogenase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.79 GFF2447 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.77 GFF2160 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 — —
Klebsiella pneumoniae MKP103 0.79 KDGMDA_28355 Serine hydroxymethyltransferase 0.77 KDGMDA_28160 IMP dehydrogenase low > 95
Klebsiella michiganensis M5al 0.79 BWI76_RS21225 serine hydroxymethyltransferase 0.76 BWI76_RS21030 IMP dehydrogenase — —
Enterobacter asburiae PDN3 0.79 EX28DRAFT_0099 Glycine/serine hydroxymethyltransferase 0.76 EX28DRAFT_0139 inosine-5'-monophosphate dehydrogenase — —
Enterobacter sp. TBS_079 0.79 MPMX20_03420 Serine hydroxymethyltransferase 0.76 MPMX20_03382 Inosine-5'-monophosphate dehydrogenase — —
Pseudomonas sp. RS175 0.75 PFR28_03786 Serine hydroxymethyltransferase 0.65 PFR28_00310 'Inosine-5'-monophosphate dehydrogenase' transl_table=11 — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.75 Psyr_4270 serine hydroxymethyltransferase 0.65 Psyr_1261 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a 0.75 Psyr_4270 serine hydroxymethyltransferase 0.65 Psyr_1261 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas orientalis W4I3 0.75 QF045_RS26575 serine hydroxymethyltransferase 0.64 QF045_RS25300 IMP dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.75 Pf6N2E2_5082 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.65 Pf6N2E2_3165 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain — —
Pseudomonas sp. SVBP6 0.74 COO64_RS02995 glyA serine hydroxymethyltransferase 0.63 COO64_RS04660 guaB IMP dehydrogenase — —
Pseudomonas fluorescens FW300-N2C3 0.74 AO356_15725 serine hydroxymethyltransferase 0.65 AO356_06525 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas putida KT2440 0.74 PP_0671 serine hydroxymethyltransferase 0.64 PP_1031 IMP dehydrogenase and single strand DNA binding factor — —
Pseudomonas fluorescens FW300-N2E3 0.74 AO353_14020 serine hydroxymethyltransferase 0.64 AO353_15950 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas sp. S08-1 0.74 OH686_16230 Serine hydroxymethyltransferase 0.65 OH686_17590 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas lactucae CFBP13502 0.74 GEMAOFIL_05008 Serine hydroxymethyltransferase 0.63 GEMAOFIL_04768 'Inosine-5'-monophosphate dehydrogenase' transl_table=11 — —
Pseudomonas sp. DMC3 0.74 GFF3963 Serine hydroxymethyltransferase 0.65 GFF4327 Inosine-5'-monophosphate dehydrogenase — —
Pseudomonas sp. BP01 0.74 JOY50_RS24625 glyA serine hydroxymethyltransferase 0.64 JOY50_RS11500 guaB IMP dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.74 PFLU_RS26195 serine hydroxymethyltransferase 0.64 PFLU_RS24735 IMP dehydrogenase — —
Pseudomonas fluorescens SBW25 0.74 PFLU_RS26195 serine hydroxymethyltransferase 0.64 PFLU_RS24735 IMP dehydrogenase — —
Pseudomonas simiae WCS417 0.74 PS417_24280 serine hydroxymethyltransferase 0.64 PS417_23075 inosine-5-monophosphate dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.74 PfGW456L13_1451 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.63 PfGW456L13_4818 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain — —
Pseudomonas stutzeri RCH2 0.74 Psest_3404 Glycine/serine hydroxymethyltransferase 0.64 Psest_1286 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.74 Pf1N1B4_2778 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.64 Pf1N1B4_840 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain — —
Pseudomonas aeruginosa PUPa3 0.74 DQ20_RS55885 glyA;go_function=glycine serine hydroxymethyltransferase 0.61 DQ20_RS43025 guaB;go_function=IMP IMP dehydrogenase — —
Marinobacter adhaerens HP15 0.74 HP15_489 glycine hydroxymethyltransferase 0.64 HP15_2051 inositol-5-monophosphate dehydrogenase — —
Pseudomonas aeruginosa MRSN321 0.74 DY961_RS23420 glyA;go_function=glycine serine hydroxymethyltransferase 0.61 DY961_RS14075 guaB;go_function=IMP IMP dehydrogenase — —
Pseudomonas segetis P6 0.74 ACVTMO_RS19725 glyA serine hydroxymethyltransferase 0.68 ACVTMO_RS07630 guaB IMP dehydrogenase — —
Pseudomonas aeruginosa PA14 0.73 IKLFDK_00500 Serine hydroxymethyltransferase 3 0.61 IKLFDK_19415 IMP dehydrogenase — —
Alteromonas macleodii MIT1002 0.73 MIT1002_02702 Serine hydroxymethyltransferase 0.71 MIT1002_02779 Inosine-5'-monophosphate dehydrogenase — —
Kangiella aquimarina DSM 16071 0.72 B158DRAFT_1908 Glycine/serine hydroxymethyltransferase 0.70 B158DRAFT_1158 inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) — —
Rhodanobacter denitrificans FW104-10B01 0.72 LRK54_RS04625 serine hydroxymethyltransferase 0.63 LRK54_RS00105 IMP dehydrogenase — —
Rhodanobacter denitrificans MT42 0.72 LRK55_RS04400 serine hydroxymethyltransferase 0.62 LRK55_RS18100 IMP dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.72 ABZR86_RS10715 serine hydroxymethyltransferase 0.64 ABZR86_RS05410 IMP dehydrogenase — —
Rhodanobacter sp000427505 FW510-R12 0.72 LRK53_RS05390 serine hydroxymethyltransferase 0.62 LRK53_RS11160 IMP dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.72 OKGIIK_11440 glyA serine hydroxymethyltransferase 0.62 OKGIIK_07095 guaB IMP dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.71 Xcc-8004.4398.1 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.61 Xcc-8004.2391.1 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain — —
Acinetobacter radioresistens SK82 0.71 MPMX26_02049 Serine hydroxymethyltransferase 0.62 MPMX26_02920 Inosine-5'-monophosphate dehydrogenase — —
Lysobacter sp. OAE881 0.71 ABIE51_RS04620 serine hydroxymethyltransferase 0.59 ABIE51_RS09475 IMP dehydrogenase — —
Paraburkholderia sabiae LMG 24235 0.70 QEN71_RS33600 serine hydroxymethyltransferase 0.64 QEN71_RS06540 IMP dehydrogenase — —
Acinetobacter baumannii LAC-4 0.70 RR41_RS06055 serine hydroxymethyltransferase 0.61 RR41_RS00905 IMP dehydrogenase — —
Castellaniella sp019104865 MT123 0.69 ABCV34_RS06400 serine hydroxymethyltransferase 0.61 ABCV34_RS04905 IMP dehydrogenase — —
Dechlorosoma suillum PS 0.64 Dsui_1265 glycine/serine hydroxymethyltransferase 0.63 Dsui_2671 inosine-5''-monophosphate dehydrogenase — —
Methylophilus sp. DMC18 0.64 GFF72 Serine hydroxymethyltransferase 0.66 GFF1138 Inosine-5'-monophosphate dehydrogenase — —
Burkholderia phytofirmans PsJN 0.63 BPHYT_RS03725 serine hydroxymethyltransferase 0.62 BPHYT_RS12020 inosine 5'-monophosphate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.63 H281DRAFT_04726 serine hydroxymethyltransferase 0.63 H281DRAFT_00634 inosine-5'-monophosphate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.63 Ac3H11_2921 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.62 Ac3H11_2857 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) — —
Paraburkholderia graminis OAS925 0.63 ABIE53_000888 glycine hydroxymethyltransferase 0.63 ABIE53_002478 IMP dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.62 HSERO_RS06140 serine hydroxymethyltransferase 0.62 HSERO_RS11015 inosine 5'-monophosphate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.62 RS_RS03670 serine hydroxymethyltransferase 0.63 RS_RS07170 IMP dehydrogenase — —
Variovorax sp. OAS795 0.62 ABID97_RS17890 serine hydroxymethyltransferase 0.60 ABID97_RS16415 IMP dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS08955 serine hydroxymethyltransferase 0.61 ABZR87_RS11965 IMP dehydrogenase — —
Variovorax sp. SCN45 0.62 GFF560 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.61 GFF209 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.62 GFF5152 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.62 GFF4356 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) — —
Ralstonia solanacearum IBSBF1503 0.62 RALBFv3_RS12895 serine hydroxymethyltransferase 0.63 RALBFv3_RS00515 IMP dehydrogenase — —
Ralstonia solanacearum UW163 0.62 UW163_RS00670 serine hydroxymethyltransferase 0.63 UW163_RS13845 IMP dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.62 RR42_RS15485 serine hydroxymethyltransferase 0.62 RR42_RS11750 inosine-5-monophosphate dehydrogenase — —
Ralstonia solanacearum PSI07 0.62 RPSI07_RS20330 serine hydroxymethyltransferase 0.63 RPSI07_RS16975 IMP dehydrogenase — —
Desulfovibrio vulgaris Miyazaki F 0.57 DvMF_3097 glyA serine hydroxymethyltransferase (RefSeq) 0.54 DvMF_3126 inosine-5'-monophosphate dehydrogenase (RefSeq) — —
Desulfovibrio vulgaris Hildenborough JW710 0.56 DVU1203 glyA serine hydroxymethyltransferase (TIGR) 0.55 DVU1044 guaB inosine-5`-monophosphate dehydrogenase (TIGR) — —
Cellulophaga baltica 18 0.54 M666_RS14985 serine hydroxymethyltransferase 0.52 M666_RS19055 IMP dehydrogenase low > 67
Phocaeicola vulgatus CL09T03C04 0.54 HMPREF1058_RS03800 serine hydroxymethyltransferase 0.52 HMPREF1058_RS03000 IMP dehydrogenase 0.69 18
Phocaeicola dorei CL03T12C01 0.54 ABI39_RS17420 serine hydroxymethyltransferase 0.52 ABI39_RS02315 IMP dehydrogenase 0.69 45
Parabacteroides merdae CL09T00C40 0.53 HMPREF1078_RS02145 serine hydroxymethyltransferase 0.24 HMPREF1078_RS14285 IMP dehydrogenase low > 61
Bacteroides ovatus ATCC 8483 0.53 BACOVA_02446 glycine hydroxymethyltransferase 0.54 BACOVA_00338 inosine-5'-monophosphate dehydrogenase — —
Bacteroides stercoris CC31F 0.53 HMPREF1181_RS15010 serine hydroxymethyltransferase 0.52 HMPREF1181_RS07435 IMP dehydrogenase 0.78 13
Bacteroides thetaiotaomicron VPI-5482 0.53 BT0738 serine hydroxymethyltransferase (NCBI ptt file) 0.52 BT3845 inosine-5'-monophosphate dehydrogenase (NCBI ptt file) 0.51 76
Echinicola vietnamensis KMM 6221, DSM 17526 0.51 Echvi_1188 Glycine/serine hydroxymethyltransferase 0.53 Echvi_1111 inosine-5'-monophosphate dehydrogenase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.50 CA264_17045 serine hydroxymethyltransferase 0.56 CA264_19750 IMP dehydrogenase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.50 CA265_RS19165 serine hydroxymethyltransferase 0.55 CA265_RS10675 IMP dehydrogenase — —

Not shown: 1 genomes with orthologs for CSW01_04820 only; 23 genomes with orthologs for CSW01_03980 only