| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_13865 | | nitrogen regulation protein NR(I) | 1.0 | CSW01_01965 | | glucose-6-phosphate isomerase | 0.42 | 13 |
| Enterobacter asburiae PDN3 | 0.73 | EX28DRAFT_4350 | | nitrogen regulation protein NR(I) | 0.79 | EX28DRAFT_4318 | | Glucose-6-phosphate isomerase | low | > 76 |
| Enterobacter sp. TBS_079 | 0.73 | MPMX20_04597 | | DNA-binding transcriptional regulator NtrC | 0.78 | MPMX20_00241 | | Glucose-6-phosphate isomerase | low | > 85 |
| Serratia liquefaciens MT49 | 0.72 | IAI46_24960 | | nitrogen regulation protein NR(I) | 0.81 | IAI46_23090 | | glucose-6-phosphate isomerase | low | > 87 |
| Escherichia fergusonii Becca | 0.72 | EFB2_04748 | | DNA-binding transcriptional regulator NtrC | 0.80 | EFB2_04577 | | Glucose-6-phosphate isomerase | 0.62 | 50 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.72 | GFF2220 | | Nitrogen regulation protein NR(I) | 0.80 | GFF1396 | | Glucose-6-phosphate isomerase (EC 5.3.1.9) | low | > 78 |
| Escherichia coli BW25113 | 0.72 | b3868 | glnG | fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) | 0.80 | b4025 | pgi | glucose-6-phosphate isomerase (NCBI) | 0.19 | 41 |
| Escherichia coli ECRC102 | 0.72 | NIAGMN_11865 | glnG | nitrogen regulation protein NR(I) | 0.80 | NIAGMN_10925 | pgi | glucose-6-phosphate isomerase | 0.58 | 62 |
| Escherichia coli ECRC98 | 0.72 | JDDGAC_17735 | glnG | nitrogen regulation protein NR(I) | 0.80 | JDDGAC_16800 | pgi | glucose-6-phosphate isomerase | — | — |
| Escherichia coli Nissle 1917 | 0.72 | ECOLIN_RS22295 | | nitrogen regulation protein NR(I) | 0.80 | ECOLIN_RS23240 | | glucose-6-phosphate isomerase | low | > 55 |
| Escherichia coli ECRC100 | 0.72 | OKFHMN_14110 | glnG | nitrogen regulation protein NR(I) | 0.80 | OKFHMN_13175 | pgi | glucose-6-phosphate isomerase | low | > 79 |
| Escherichia coli ECRC99 | 0.72 | KEDOAH_14040 | glnG | nitrogen regulation protein NR(I) | 0.80 | KEDOAH_14985 | pgi | glucose-6-phosphate isomerase | — | — |
| Escherichia coli ECRC101 | 0.72 | MCAODC_04610 | glnG | nitrogen regulation protein NR(I) | 0.80 | MCAODC_03675 | pgi | glucose-6-phosphate isomerase | low | > 87 |
| Escherichia coli ECOR27 | 0.72 | NOLOHH_06240 | glnG | nitrogen regulation protein NR(I) | 0.80 | NOLOHH_05335 | pgi | glucose-6-phosphate isomerase | low | > 76 |
| Klebsiella pneumoniae MKP103 | 0.72 | KDGMDA_09000 | | nitrogen regulation protein NR(I) | 0.79 | KDGMDA_10235 | | glucose-6-phosphate isomerase | low | > 95 |
| Escherichia coli ECRC62 | 0.72 | BNILDI_05290 | glnG | nitrogen regulation protein NR(I) | 0.80 | BNILDI_06185 | pgi | glucose-6-phosphate isomerase | low | > 75 |
| Klebsiella michiganensis M5al | 0.72 | BWI76_RS00385 | | nitrogen assimilation regulatory protein | 0.79 | BWI76_RS01800 | | glucose-6-phosphate isomerase | low | > 92 |
| Escherichia coli ECOR38 | 0.72 | HEPCGN_12740 | glnG | nitrogen regulation protein NR(I) | 0.80 | HEPCGN_11685 | pgi | glucose-6-phosphate isomerase | low | > 88 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.72 | OHPLBJKB_04184 | | DNA-binding transcriptional regulator NtrC | 0.80 | OHPLBJKB_04021 | | Glucose-6-phosphate isomerase | low | > 74 |
| Escherichia coli BL21 | 0.72 | ECD_03753 | | fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein | 0.80 | ECD_03897 | | glucosephosphate isomerase | low | > 61 |
| Rahnella sp. WP5 | 0.72 | EX31_RS15880 | | nitrogen regulation protein NR(I) | 0.80 | EX31_RS11815 | | glucose-6-phosphate isomerase | low | > 89 |
| Pantoea sp. MT58 | 0.72 | IAI47_00450 | | nitrogen regulation protein NR(I) | 0.80 | IAI47_17965 | | glucose-6-phosphate isomerase | low | > 76 |
| Erwinia amylovora T8 | 0.72 | OLJFJH_05495 | | nitrogen regulation protein NR(I) | 0.79 | OLJFJH_03630 | | glucose-6-phosphate isomerase | — | — |
| Pantoea agglomerans CFBP13505 P0401 | 0.71 | PagCFBP13505_RS18895 | | nitrogen regulation protein NR(I) | 0.80 | PagCFBP13505_RS22280 | | glucose-6-phosphate isomerase | low | > 74 |
| Pectobacterium carotovorum WPP14 | 0.71 | HER17_RS21440 | | nitrogen regulation protein NR(I) | 0.80 | HER17_RS02340 | | glucose-6-phosphate isomerase | low | > 75 |
| Dickeya dadantii 3937 | 0.71 | DDA3937_RS00125 | | nitrogen regulation protein NR(I) | 0.82 | DDA3937_RS19015 | | glucose-6-phosphate isomerase | low | > 74 |
| Dickeya dianthicola 67-19 | 0.71 | HGI48_RS21235 | | nitrogen regulation protein NR(I) | 0.81 | HGI48_RS19100 | | glucose-6-phosphate isomerase | low | > 71 |
| Dickeya dianthicola ME23 | 0.71 | DZA65_RS22210 | | nitrogen regulation protein NR(I) | 0.81 | DZA65_RS20220 | | glucose-6-phosphate isomerase | low | > 75 |
| Erwinia tracheiphila SCR3 | 0.71 | LU632_RS22135 | glnG | nitrogen regulation protein NR(I) | 0.80 | LU632_RS22365 | pgi | glucose-6-phosphate isomerase | low | > 73 |
| Erwinia tracheiphila HP pepo 2.2 | 0.70 | IJEDHG_08285 | glnG | nitrogen regulation protein NR(I) | 0.80 | IJEDHG_08505 | pgi | glucose-6-phosphate isomerase | low | > 61 |
| Shewanella oneidensis MR-1 | 0.69 | SO4472 | ntrC | nitrogen regulation protein NR(I) (NCBI ptt file) | 0.53 | SO3547 | pgi | glucose-6-phosphate isomerase (NCBI ptt file) | — | — |
| Shewanella amazonensis SB2B | 0.69 | Sama_3427 | | response regulator receiver protein (RefSeq) | 0.50 | Sama_0912 | pgi | glucose-6-phosphate isomerase (RefSeq) | — | — |
| Shewanella sp. ANA-3 | 0.69 | Shewana3_0258 | | nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) | 0.52 | Shewana3_3148 | pgi | glucose-6-phosphate isomerase (RefSeq) | — | — |
| Shewanella loihica PV-4 | 0.69 | Shew_3561 | | nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) | 0.52 | Shew_1088 | pgi | glucose-6-phosphate isomerase (RefSeq) | — | — |
| Alteromonas macleodii MIT1002 | 0.69 | MIT1002_03186 | | Nitrogen regulation protein NR(I) | 0.50 | MIT1002_03081 | | Glucose-6-phosphate isomerase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.67 | AO353_12145 | | nitrogen regulation protein NR(I) | 0.51 | AO353_14370 | | glucose-6-phosphate isomerase | low | > 101 |
| Pseudomonas fluorescens FW300-N2C3 | 0.66 | AO356_09730 | | nitrogen regulation protein NR(I) | 0.51 | AO356_16050 | | glucose-6-phosphate isomerase | 0.38 | 52 |
| Pseudomonas lactucae CFBP13502 | 0.66 | GEMAOFIL_00547 | | DNA-binding transcriptional regulator NtrC | 0.50 | GEMAOFIL_04935 | | Glucose-6-phosphate isomerase | low | > 96 |
| Pseudomonas segetis P6 | 0.66 | MPMX49_04287 | | DNA-binding transcriptional regulator NtrC | 0.52 | MPMX49_01219 | | Glucose-6-phosphate isomerase | — | — |
| Pseudomonas fluorescens SBW25 | 0.66 | PFLU_RS01685 | | nitrogen regulation protein NR(I) | 0.50 | PFLU_RS25760 | | glucose-6-phosphate isomerase | low | > 109 |
| Pseudomonas putida KT2440 | 0.66 | PP_5048 | | two-component system DNA-binding transcriptional dual regulator GlnL/GlnG | 0.50 | PP_1808 | | glucose-6-phosphate isomerase | low | > 96 |
| Pseudomonas simiae WCS417 | 0.66 | PS417_01635 | | nitrogen regulation protein NR(I) | 0.50 | PS417_23920 | | glucose-6-phosphate isomerase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.66 | Pf1N1B4_1611 | | Nitrogen regulation protein NR(I) | 0.51 | Pf1N1B4_2850 | | Glucose-6-phosphate isomerase (EC 5.3.1.9) | 0.54 | 29 |
| Pseudomonas fluorescens GW456-L13 | 0.66 | PfGW456L13_347 | | Nitrogen regulation protein NR(I) | 0.51 | PfGW456L13_1518 | | Glucose-6-phosphate isomerase (EC 5.3.1.9) | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.66 | PFLU_RS01685 | | nitrogen regulation protein NR(I) | 0.50 | PFLU_RS25760 | | glucose-6-phosphate isomerase | 0.18 | 81 |
| Pseudomonas fluorescens FW300-N2E2 | 0.66 | Pf6N2E2_3826 | | Nitrogen regulation protein NR(I) | 0.51 | Pf6N2E2_5150 | | Glucose-6-phosphate isomerase (EC 5.3.1.9) | 0.40 | 82 |
| Pseudomonas sp. DMC3 | 0.66 | GFF4081 | | DNA-binding transcriptional regulator NtrC | 0.50 | GFF4025 | | Glucose-6-phosphate isomerase | low | > 89 |
| Pseudomonas orientalis W4I3 | 0.66 | QF045_RS04705 | | nitrogen regulation protein NR(I) | 0.50 | QF045_RS26180 | | glucose-6-phosphate isomerase | low | > 93 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.66 | Psyr_4822 | | Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) | 0.49 | Psyr_0826 | | glucose-6-phosphate isomerase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.66 | Psyr_4822 | | Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) | 0.49 | Psyr_0826 | | glucose-6-phosphate isomerase | low | > 86 |
| Pseudomonas sp. SVBP6 | 0.66 | COO64_RS13325 | ntrC | nitrogen regulation protein NR(I) | 0.51 | COO64_RS15115 | pgi | glucose-6-phosphate isomerase | 0.35 | 36 |
| Pseudomonas sp. RS175 | 0.66 | PFR28_04944 | | DNA-binding transcriptional regulator NtrC | 0.51 | PFR28_03724 | | Glucose-6-phosphate isomerase | low | > 88 |
| Pseudomonas sp. S08-1 | 0.66 | OH686_10640 | | nitrogen regulation protein NR(I) | 0.51 | OH686_17230 | | Glucose-6-phosphate isomerase | — | — |
| Pseudomonas aeruginosa PA14 | 0.66 | IKLFDK_27895 | | two-component system response regulator NtrC | 0.51 | IKLFDK_29940 | | glucose-6-phosphate isomerase | — | — |
| Pseudomonas aeruginosa PUPa3 | 0.66 | DQ20_RS50645 | ntrC;inference=COORDINATES | two-component system response regulator NtrC | 0.51 | DQ20_RS52630 | pgi;go_function=glucose-6-phosphate | glucose-6-phosphate isomerase | — | — |
| Pseudomonas aeruginosa MRSN321 | 0.66 | DY961_RS11455 | ntrC;inference=COORDINATES | two-component system response regulator NtrC | 0.51 | DY961_RS09400 | pgi;go_function=glucose-6-phosphate | glucose-6-phosphate isomerase | — | — |
| Pseudomonas stutzeri RCH2 | 0.65 | Psest_3932 | | nitrogen regulation protein NR(I) | 0.50 | Psest_0993 | | Glucose-6-phosphate isomerase | low | > 67 |
| Acinetobacter radioresistens SK82 | 0.65 | MPMX26_01292 | | DNA-binding transcriptional regulator NtrC | 0.42 | MPMX26_00065 | | Glucose-6-phosphate isomerase | low | > 36 |
| Marinobacter adhaerens HP15 | 0.65 | HP15_425 | | two-component response regulator NtrC | 0.50 | HP15_322 | | glucose-6-phosphate isomerase | — | — |
| Acinetobacter baumannii LAC-4 | 0.64 | RR41_RS08030 | | nitrogen regulation protein NR(I) | 0.43 | RR41_RS18530 | | glucose-6-phosphate isomerase | low | > 55 |
| Methylophilus sp. DMC18 | 0.60 | GFF2024 | | DNA-binding transcriptional regulator NtrC | 0.63 | GFF1243 | | Glucose-6-phosphate isomerase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.57 | HSERO_RS15680 | | chemotaxis protein CheY | 0.52 | HSERO_RS12485 | | glucose-6-phosphate isomerase | low | > 78 |
| Dechlorosoma suillum PS | 0.56 | Dsui_1051 | | nitrogen regulation protein NR(I) | 0.50 | Dsui_1239 | | glucose-6-phosphate isomerase | — | — |
| Ralstonia solanacearum GMI1000 | 0.56 | RS_RS06320 | | nitrogen regulation protein NR(I) | 0.47 | RS_RS08695 | | glucose-6-phosphate isomerase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.55 | RALBFv3_RS15540 | | nitrogen regulation protein NR(I) | 0.46 | RALBFv3_RS01300 | | glucose-6-phosphate isomerase | — | — |
| Ralstonia solanacearum UW163 | 0.55 | UW163_RS13000 | | nitrogen regulation protein NR(I) | 0.46 | UW163_RS14610 | | glucose-6-phosphate isomerase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.55 | ABZR87_RS11070 | | nitrogen regulation protein NR(I) | 0.46 | ABZR87_RS12745 | | glucose-6-phosphate isomerase | — | — |
| Ralstonia solanacearum PSI07 | 0.55 | RPSI07_RS17815 | | nitrogen regulation protein NR(I) | 0.46 | RPSI07_RS16175 | | glucose-6-phosphate isomerase | low | > 81 |
| Cupriavidus basilensis FW507-4G11 | 0.54 | RR42_RS12980 | | chemotaxis protein CheY | 0.49 | RR42_RS09060 | | glucose-6-phosphate isomerase | low | > 128 |
| Paraburkholderia sabiae LMG 24235 | 0.54 | QEN71_RS05675 | | nitrogen regulation protein NR(I) | 0.46 | QEN71_RS21935 | | glucose-6-phosphate isomerase | low | > 153 |
| Variovorax sp. SCN45 | 0.54 | GFF3066 | | Nitrogen regulation protein NR(I), GlnG (=NtrC) | 0.41 | GFF5267 | | Glucose-6-phosphate isomerase (EC 5.3.1.9) | — | — |
| Variovorax sp. OAS795 | 0.54 | ABID97_RS09945 | | nitrogen regulation protein NR(I) | 0.41 | ABID97_RS07100 | | glucose-6-phosphate isomerase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.53 | GFF5269 | | Nitrogen regulation protein NR(I) | 0.37 | GFF5497 | | Glucose-6-phosphate isomerase (EC 5.3.1.9) | low | > 90 |
| Burkholderia phytofirmans PsJN | 0.53 | BPHYT_RS12935 | | chemotaxis protein CheY | 0.46 | BPHYT_RS09500 | | glucose-6-phosphate isomerase | 0.46 | 60 |
| Paraburkholderia graminis OAS925 | 0.53 | ABIE53_002804 | | two-component system nitrogen regulation response regulator GlnG | 0.44 | ABIE53_002138 | | glucose-6-phosphate isomerase | low | > 113 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.53 | H281DRAFT_00454 | | nitrogen metabolism transcriptional regulator, NtrC, Fis family | 0.44 | H281DRAFT_00906 | | glucose-6-phosphate isomerase | — | — |
| Lysobacter sp. OAE881 | 0.50 | ABIE51_RS01360 | | nitrogen regulation protein NR(I) | 0.30 | ABIE51_RS08040 | | glucose-6-phosphate isomerase | low | > 62 |
| Castellaniella sp019104865 MT123 | 0.49 | ABCV34_RS03540 | | nitrogen regulation protein NR(I) | 0.29 | ABCV34_RS11120 | | glucose-6-phosphate isomerase | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.48 | Xcc-8004.252.1 | | Nitrogen regulation protein NtrC | 0.33 | Xcc-8004.3049.1 | | Glucose-6-phosphate isomerase (EC 5.3.1.9) | low | > 74 |
| Rhodanobacter denitrificans FW104-10B01 | 0.46 | LRK54_RS07980 | | nitrogen regulation protein NR(I) | 0.52 | LRK54_RS08755 | | glucose-6-phosphate isomerase | — | — |
| Rhodanobacter denitrificans MT42 | 0.46 | LRK55_RS07730 | | nitrogen regulation protein NR(I) | 0.53 | LRK55_RS08520 | | glucose-6-phosphate isomerase | — | — |
| Rhodanobacter sp000427505 FW510-R12 | 0.45 | LRK53_RS00570 | | nitrogen regulation protein NR(I) | 0.52 | LRK53_RS18080 | | glucose-6-phosphate isomerase | low | > 59 |
| Rhodanobacter sp. FW510-T8 | 0.45 | OKGIIK_14465 | ntrC | nitrogen regulation protein NR(I) | 0.51 | OKGIIK_15520 | pgi | glucose-6-phosphate isomerase | low | > 53 |
| Dyella japonica UNC79MFTsu3.2 | 0.45 | ABZR86_RS15515 | | nitrogen regulation protein NR(I) | 0.36 | ABZR86_RS00830 | | glucose-6-phosphate isomerase | low | > 74 |
| Xanthobacter sp. DMC5 | 0.41 | GFF848 | | DNA-binding transcriptional regulator NtrC | 0.46 | GFF3233 | | Glucose-6-phosphate isomerase | — | — |
| Sinorhizobium meliloti 1021 | 0.41 | SMc01043 | | nitrogen assimilation regulatory protein | 0.51 | SMc02163 | | glucose-6-phosphate isomerase | — | — |
| Bosea sp. OAE506 | 0.40 | ABIE41_RS16785 | | nitrogen regulation protein NR(I) | 0.50 | ABIE41_RS07535 | | glucose-6-phosphate isomerase | low | > 77 |
| Magnetospirillum magneticum AMB-1 | 0.40 | AMB_RS11950 | | nitrogen regulation protein NR(I) | 0.61 | AMB_RS22330 | | glucose-6-phosphate isomerase | — | — |
| Azospirillum sp. SherDot2 | 0.40 | MPMX19_01112 | | DNA-binding transcriptional regulator NtrC | 0.63 | MPMX19_00519 | | Glucose-6-phosphate isomerase | — | — |
| Rhizobium sp. OAE497 | 0.40 | ABIE40_RS09090 | | nitrogen regulation protein NR(I) | 0.51 | ABIE40_RS02150 | | glucose-6-phosphate isomerase | — | — |
| Azospirillum brasilense Sp245 | 0.40 | AZOBR_RS14430 | | chemotaxis protein CheY | 0.64 | AZOBR_RS05045 | | glucose-6-phosphate isomerase | — | — |
| Agrobacterium fabrum C58 | 0.39 | Atu1446 | | two component response regulator | 0.51 | Atu0404 | | glucose-6-phosphate isomerase | — | — |
| Rhodospirillum rubrum S1H | 0.39 | Rru_A1678 | | Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family (NCBI) | 0.61 | Rru_A2947 | | Glucose-6-phosphate isomerase (NCBI) | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.39 | Ga0059261_0137 | | nitrogen regulation protein NR(I) | 0.30 | Ga0059261_1948 | | Glucose-6-phosphate isomerase | low | > 68 |
| Sphingobium sp. HT1-2 | 0.38 | GFF1148 | | Nitrogen regulation protein NR(I), GlnG (=NtrC) | 0.29 | GFF120 | | Glucose-6-phosphate isomerase (EC 5.3.1.9) | low | > 95 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.34 | CA264_04380 | | response regulator | 0.59 | CA264_07470 | | glucose-6-phosphate isomerase | low | > 74 |
| Caulobacter crescentus NA1000 | 0.33 | CCNA_03424 | | AAA-family response regulator tacA | 0.39 | CCNA_00222 | | glucose-6-phosphate isomerase/glucose-6 phosphate 1-epimerase | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.33 | CCNA_03424 | | AAA-family response regulator tacA | 0.39 | CCNA_00222 | | glucose-6-phosphate isomerase/glucose-6 phosphate 1-epimerase | — | — |
| Cellulophaga baltica 18 | 0.33 | M666_RS19210 | | sigma-54 dependent transcriptional regulator | 0.62 | M666_RS03705 | | glucose-6-phosphate isomerase | low | > 67 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.32 | A4249_RS09115 | | sigma-54 dependent transcriptional regulator | 0.37 | A4249_RS14585 | | glucose-6-phosphate isomerase | low | > 48 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.32 | ABZR88_RS00090 | | sigma-54 dependent transcriptional regulator | 0.74 | ABZR88_RS03585 | | glucose-6-phosphate isomerase | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.31 | CA265_RS01040 | | sigma-54-dependent Fis family transcriptional regulator | 0.72 | CA265_RS17975 | | glucose-6-phosphate isomerase | — | — |
| Dinoroseobacter shibae DFL-12 | 0.30 | Dshi_1572 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | 0.45 | Dshi_1682 | | Glucose-6-phosphate isomerase (RefSeq) | — | — |
| Phaeobacter inhibens DSM 17395 | 0.30 | PGA1_c14810 | | nitrogen assimilation regulatory protein NtrX | 0.47 | PGA1_c27980 | | glucose-6-phosphate isomerase Pgi | — | — |
Not shown: 11 genomes with orthologs for CSW01_13865 only; 6 genomes with orthologs for CSW01_01965 only