Conservation of cofitness between BT0790 and BT3845 in Bacteroides thetaiotaomicron VPI-5482

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT0790 phosphomethylpyrimidine kinase (NCBI ptt file) 1.0 BT3845 inosine-5'-monophosphate dehydrogenase (NCBI ptt file) 0.44 8
Bacteroides ovatus ATCC 8483 0.85 BACOVA_02530 phosphomethylpyrimidine kinase 0.98 BACOVA_00338 inosine-5'-monophosphate dehydrogenase — —
Bacteroides stercoris CC31F 0.58 HMPREF1181_RS14705 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 HMPREF1181_RS07435 IMP dehydrogenase low > 56
Phocaeicola vulgatus CL09T03C04 0.58 HMPREF1058_RS06820 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 HMPREF1058_RS03000 IMP dehydrogenase low > 67
Phocaeicola dorei CL03T12C01 0.57 ABI39_RS20615 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 ABI39_RS02315 IMP dehydrogenase 0.52 71
Parabacteroides merdae CL09T00C40 0.48 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.24 HMPREF1078_RS14285 IMP dehydrogenase low > 61
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_0215 phosphomethylpyrimidine kinase 0.62 Echvi_1111 inosine-5'-monophosphate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.67 CA265_RS10675 IMP dehydrogenase — —
Acidovorax sp. GW101-3H11 0.41 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.57 Ac3H11_2857 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.57 GFF4356 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.40 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.64 ABZR88_RS10330 IMP dehydrogenase — —
Bifidobacterium breve UCC2003 0.39 BBR_RS17215 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 BBR_RS18040 IMP dehydrogenase — —
Bosea sp. OAE506 0.39 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.52 ABIE41_RS15185 IMP dehydrogenase — —
Rhizobium sp. OAE497 0.38 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.55 ABIE40_RS03465 IMP dehydrogenase — —
Vibrio cholerae E7946 ATCC 55056 0.37 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.54 CSW01_03980 IMP dehydrogenase low > 62
Rhodospirillum rubrum S1H 0.37 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) 0.50 Rru_A0244 IMP dehydrogenase (NCBI) — —
Sinorhizobium meliloti 1021 0.37 SM_b20962 phoshomethylpyrimidine kinase 0.52 SMc00815 inosine 5'-monophosphate dehydrogenase low > 103
Castellaniella sp019104865 MT123 0.37 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.58 ABCV34_RS04905 IMP dehydrogenase — —
Agrobacterium fabrum C58 0.37 Atu3290 phosphomethylpyrimidine kinase 0.46 Atu0624 inosine-5`-monophosphate dehydrogenase — —
Pectobacterium carotovorum WPP14 0.36 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.52 HER17_RS06155 IMP dehydrogenase low > 75
Serratia liquefaciens MT49 0.36 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.51 IAI46_19210 IMP dehydrogenase — —
Enterobacter sp. TBS_079 0.36 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.51 MPMX20_03382 Inosine-5'-monophosphate dehydrogenase low > 85
Escherichia coli BL21 0.36 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase 0.50 ECD_02400 IMP dehydrogenase low > 60
Ralstonia solanacearum GMI1000 0.35 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.57 RS_RS07170 IMP dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.57 ABZR87_RS11965 IMP dehydrogenase — —
Enterobacter asburiae PDN3 0.35 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.51 EX28DRAFT_0139 inosine-5'-monophosphate dehydrogenase — —
Variovorax sp. OAS795 0.35 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.56 ABID97_RS16415 IMP dehydrogenase — —
Escherichia coli ECRC101 0.35 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 OKFHMN_21760 guaB IMP dehydrogenase — —
Escherichia coli ECRC102 0.35 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 NIAGMN_19530 guaB IMP dehydrogenase — —
Escherichia fergusonii Becca 0.35 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.50 EFB2_01385 Inosine-5'-monophosphate dehydrogenase low > 86
Escherichia coli ECRC62 0.35 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 BNILDI_12210 guaB IMP dehydrogenase — —
Escherichia coli BW25113 0.35 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.50 b2508 guaB inositol-5-monophosphate dehydrogenase (NCBI) — —
Escherichia coli ECRC101 0.35 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 MCAODC_12290 guaB IMP dehydrogenase — —
Escherichia coli ECRC98 0.35 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 JDDGAC_25435 guaB IMP dehydrogenase — —
Escherichia coli ECOR27 0.35 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 NOLOHH_13410 guaB IMP dehydrogenase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.35 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.50 OHPLBJKB_01201 'Inosine-5'-monophosphate dehydrogenase' transl_table=11 low > 73
Escherichia coli ECOR38 0.35 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 HEPCGN_20900 guaB IMP dehydrogenase low > 85
Escherichia coli ECRC99 0.35 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 KEDOAH_06460 guaB IMP dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.57 RALBFv3_RS00515 IMP dehydrogenase — —
Ralstonia solanacearum UW163 0.35 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.57 UW163_RS13845 IMP dehydrogenase — —
Rahnella sp. WP5 0.35 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 EX31_RS20450 IMP dehydrogenase low > 89
Ralstonia solanacearum PSI07 0.35 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.57 RPSI07_RS16975 IMP dehydrogenase — —
Escherichia coli Nissle 1917 0.35 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 ECOLIN_RS14240 IMP dehydrogenase — —
Caulobacter crescentus NA1000 0.35 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.51 CCNA_01689 inosine-5'-monophosphate dehydrogenase — —
Caulobacter crescentus NA1000 Δfur 0.35 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.51 CCNA_01689 inosine-5'-monophosphate dehydrogenase — —
Klebsiella michiganensis M5al 0.35 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.51 BWI76_RS21030 IMP dehydrogenase — —
Erwinia tracheiphila SCR3 0.34 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.51 LU632_RS17755 guaB IMP dehydrogenase low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.34 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.52 GFF2160 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 low > 78
Dickeya dadantii 3937 0.34 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.52 DDA3937_RS15420 IMP dehydrogenase low > 74
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS12250 phosphomethylpyrimidine kinase 0.56 BPHYT_RS12020 inosine 5'-monophosphate dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS01370 phosphomethylpyrimidine kinase 0.56 RR42_RS11750 inosine-5-monophosphate dehydrogenase — —
Fusobacterium nucleatum SB010 0.33 HUW76_10300 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.57 HUW76_04090 IMP dehydrogenase — —
Paraburkholderia sabiae LMG 24235 0.33 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.57 QEN71_RS06540 IMP dehydrogenase — —
Azospirillum brasilense Sp245 0.33 AZOBR_RS07045 phosphomethylpyrimidine kinase 0.55 AZOBR_RS16110 inosine-5`-monophosphate dehydrogenase — —
Dickeya dianthicola 67-19 0.33 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.52 HGI48_RS15535 IMP dehydrogenase low > 71
Paraburkholderia bryophila 376MFSha3.1 0.33 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase 0.56 H281DRAFT_00634 inosine-5'-monophosphate dehydrogenase — —
Pantoea sp. MT58 0.33 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.51 IAI47_05105 IMP dehydrogenase — —
Dickeya dianthicola ME23 0.33 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.52 DZA65_RS16610 IMP dehydrogenase low > 75
Rhodopseudomonas palustris CGA009 0.32 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.51 TX73_011355 IMP dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.32 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.54 AMB_RS19150 IMP dehydrogenase — —
Paraburkholderia graminis OAS925 0.32 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.55 ABIE53_002478 IMP dehydrogenase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.30 A4249_RS15985 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 A4249_RS03025 IMP dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.30 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.56 ABZR86_RS05410 IMP dehydrogenase — —
Azospirillum sp. SherDot2 0.30 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.54 MPMX19_01690 Inosine-5'-monophosphate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.29 Xcc-8004.3091.1 hypothetical protein 0.51 Xcc-8004.2391.1 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain — —
Desulfovibrio vulgaris Hildenborough JW710 0.29 DVU0931 thiD phosphomethylpyrimidine kinase (TIGR) 0.53 DVU1044 guaB inosine-5`-monophosphate dehydrogenase (TIGR) — —
Mycobacterium tuberculosis H37Rv 0.28 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) 0.52 Rv3411c Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase) (imp oxidoreductase) (inosine-5'-monophosphate oxidoreductase) (IMPDH) (IMPD) — —
Dinoroseobacter shibae DFL-12 0.27 Dshi_0915 phosphomethylpyrimidine kinase (RefSeq) 0.54 Dshi_1646 inosine-5'-monophosphate dehydrogenase (RefSeq) low > 64
Dechlorosoma suillum PS 0.27 Dsui_0662 phosphomethylpyrimidine kinase 0.57 Dsui_2671 inosine-5''-monophosphate dehydrogenase — —
Lysobacter sp. OAE881 0.27 ABIE51_RS07970 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 ABIE51_RS09475 IMP dehydrogenase — —
Desulfovibrio vulgaris Miyazaki F 0.27 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) 0.51 DvMF_3126 inosine-5'-monophosphate dehydrogenase (RefSeq) — —
Pseudomonas putida KT2440 0.26 PP_4782 Phosphomethylpyrimidine kinase 0.52 PP_1031 IMP dehydrogenase and single strand DNA binding factor — —
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.53 PFLU_RS24735 IMP dehydrogenase — —
Pseudomonas fluorescens SBW25 0.25 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.53 PFLU_RS24735 IMP dehydrogenase — —
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_06350 hydrogenase 0.54 AO353_15950 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas simiae WCS417 0.25 PS417_24600 hydrogenase 0.53 PS417_23075 inosine-5-monophosphate dehydrogenase — —
Sphingomonas koreensis DSMZ 15582 0.24 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 Ga0059261_0893 inosine-5'-monophosphate dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.24 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.55 OKGIIK_07095 guaB IMP dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.24 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.52 PfGW456L13_4818 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain — —
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_15435 hydrogenase 0.55 AO356_06525 inosine-5'-monophosphate dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.24 HSERO_RS02135 phosphomethylpyrimidine kinase 0.54 HSERO_RS11015 inosine 5'-monophosphate dehydrogenase — —
Pseudomonas stutzeri RCH2 0.23 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.54 Psest_1286 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas sp. S08-1 0.23 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD 0.54 OH686_17590 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.23 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.53 Psyr_1261 inosine-5'-monophosphate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a 0.23 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.53 Psyr_1261 inosine-5'-monophosphate dehydrogenase — —
Acinetobacter radioresistens SK82 0.23 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.52 MPMX26_02920 Inosine-5'-monophosphate dehydrogenase — —
Pseudomonas sp. RS175 0.21 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.55 PFR28_00310 'Inosine-5'-monophosphate dehydrogenase' transl_table=11 — —
Pseudomonas fluorescens FW300-N1B4 0.21 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.54 Pf1N1B4_840 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain — —
Pseudomonas fluorescens FW300-N2E2 0.20 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.55 Pf6N2E2_3165 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_20430 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.66 CA264_19750 IMP dehydrogenase low > 74
Phaeobacter inhibens DSM 17395 0.19 PGA1_c09030 phosphomethylpyrimidine kinase ThiD 0.53 PGA1_c15220 inosine-5'-monophosphate dehydrogenase GuaB low > 62

Not shown: 1 genomes with orthologs for BT0790 only; 12 genomes with orthologs for BT3845 only