Conservation of cofitness between BT3073 and BT3195 in Bacteroides thetaiotaomicron VPI-5482

86 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT3073 putative TIM-barrel enzyme, possible dehydrogenase, contains a highly conserved dihydrouridine synthase domain (NCBI ptt file) 1.0 BT3195 conserved hypothetical protein (NCBI ptt file) 0.42 15
Bacteroides ovatus ATCC 8483 0.94 BACOVA_02724 TIM-barrel protein, nifR3 family 0.97 BACOVA_02895 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 94
Bacteroides stercoris CC31F 0.89 HMPREF1181_RS01530 tRNA dihydrouridine synthase DusB 0.94 HMPREF1181_RS01770 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 56
Phocaeicola vulgatus CL09T03C04 0.86 HMPREF1058_RS10945 tRNA dihydrouridine synthase DusB 0.88 HMPREF1058_RS11280 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 67
Phocaeicola dorei CL03T12C01 0.85 ABI39_RS06125 tRNA dihydrouridine synthase DusB 0.88 ABI39_RS05650 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB 0.65 17
Parabacteroides merdae CL09T00C40 0.78 HMPREF1078_RS05375 tRNA dihydrouridine synthase DusB 0.74 HMPREF1078_RS17135 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 61
Pontibacter actiniarum KMM 6156, DSM 19842 0.56 CA264_17860 tRNA dihydrouridine synthase DusB 0.53 CA264_05315 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 74
Echinicola vietnamensis KMM 6221, DSM 17526 0.54 Echvi_1531 putative TIM-barrel protein, nifR3 family 0.54 Echvi_2376 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB low > 79
Mucilaginibacter yixingensis YX-36 DSM 26809 0.52 ABZR88_RS22340 tRNA dihydrouridine synthase DusB 0.51 ABZR88_RS18330 MiaB/RimO family radical SAM methylthiotransferase low > 71
Pedobacter sp. GW460-11-11-14-LB5 0.52 CA265_RS21125 tRNA dihydrouridine synthase DusB 0.48 CA265_RS21675 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 88
Magnetospirillum magneticum AMB-1 0.35 AMB_RS11940 tRNA dihydrouridine synthase DusB 0.32 AMB_RS22585 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 64
Alteromonas macleodii MIT1002 0.34 MIT1002_03957 putative tRNA-dihydrouridine synthase 0.37 MIT1002_01480 (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB low > 70
Paraburkholderia bryophila 376MFSha3.1 0.33 H281DRAFT_04249 tRNA-U20-dihydrouridine synthase 0.34 H281DRAFT_04239 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 103
Shewanella amazonensis SB2B 0.33 Sama_3225 tRNA-dihydrouridine synthase B (RefSeq) 0.34 Sama_2575 tRNA-i(6)A37 modification enzyme MiaB (RefSeq) low > 62
Castellaniella sp019104865 MT123 0.33 ABCV34_RS07960 tRNA dihydrouridine synthase DusB 0.38 ABCV34_RS15345 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB 0.79 33
Ralstonia sp. UNC404CL21Col 0.33 ABZR87_RS07650 tRNA dihydrouridine synthase DusB 0.35 ABZR87_RS07780 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 80
Ralstonia solanacearum UW163 0.33 UW163_RS01890 tRNA dihydrouridine synthase DusB 0.34 UW163_RS01760 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
Ralstonia solanacearum IBSBF1503 0.33 RALBFv3_RS11695 tRNA dihydrouridine synthase DusB 0.34 RALBFv3_RS11825 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 76
Pseudomonas sp. S08-1 0.33 OH686_07610 tRNA-dihydrouridine synthase DusB 0.35 OH686_09215 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 80
Ralstonia solanacearum PSI07 0.33 RPSI07_RS21520 tRNA dihydrouridine synthase DusB 0.34 RPSI07_RS21380 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 81
Pseudomonas stutzeri RCH2 0.33 Psest_1016 putative TIM-barrel protein, nifR3 family 0.33 Psest_0532 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB low > 67
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS02730 tRNA-dihydrouridine synthase B 0.35 RR42_RS02855 dimethylallyladenosine tRNA methylthiotransferase low > 128
Kangiella aquimarina DSM 16071 0.33 B158DRAFT_0164 tRNA-U20-dihydrouridine synthase 0.33 B158DRAFT_0099 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB low > 40
Serratia liquefaciens MT49 0.33 IAI46_22775 tRNA dihydrouridine synthase DusB 0.35 IAI46_06025 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 86
Rahnella sp. WP5 0.33 EX31_RS12180 tRNA dihydrouridine synthase DusB 0.34 EX31_RS23205 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 89
Acinetobacter radioresistens SK82 0.33 MPMX26_02127 tRNA-dihydrouridine synthase B 0.32 MPMX26_02667 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 36
Paraburkholderia sabiae LMG 24235 0.33 QEN71_RS26770 tRNA dihydrouridine synthase DusB 0.35 QEN71_RS02195 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 153
Enterobacter sp. TBS_079 0.33 MPMX20_04169 tRNA-dihydrouridine synthase B 0.34 MPMX20_01311 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 85
Dickeya dianthicola ME23 0.32 DZA65_RS01355 tRNA dihydrouridine synthase DusB 0.34 DZA65_RS06640 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 75
Ralstonia solanacearum GMI1000 0.32 RS_RS02515 tRNA dihydrouridine synthase DusB 0.34 RS_RS02645 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 80
Dyella japonica UNC79MFTsu3.2 0.32 ABZR86_RS11525 tRNA dihydrouridine synthase DusB 0.34 ABZR86_RS09895 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 74
Shewanella oneidensis MR-1 0.32 SO0394 conserved hypothetical protein (NCBI ptt file) 0.33 SO1181 miaB tRNA-i(6)A37 modification enzyme MiaB (NCBI ptt file) low > 76
Klebsiella michiganensis M5al 0.32 BWI76_RS25565 tRNA dihydrouridine synthase DusB 0.36 BWI76_RS08135 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
Dickeya dianthicola 67-19 0.32 HGI48_RS01295 tRNA dihydrouridine synthase DusB 0.34 HGI48_RS06295 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 71
Shewanella sp. ANA-3 0.32 Shewana3_0399 nifR3 family TIM-barrel protein (RefSeq) 0.33 Shewana3_1008 tRNA-i(6)A37 thiotransferase enzyme MiaB (RefSeq) low > 73
Dickeya dadantii 3937 0.32 DDA3937_RS01375 tRNA dihydrouridine synthase DusB 0.34 DDA3937_RS06250 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 74
Enterobacter asburiae PDN3 0.32 EX28DRAFT_3313 putative TIM-barrel protein, nifR3 family 0.34 EX28DRAFT_2310 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB low > 76
Burkholderia phytofirmans PsJN 0.32 BPHYT_RS16585 tRNA-dihydrouridine synthase B 0.35 BPHYT_RS16535 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 109
Azospirillum sp. SherDot2 0.32 MPMX19_01110 tRNA-dihydrouridine synthase B 0.33 MPMX19_02511 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 112
Escherichia coli ECRC62 0.31 BNILDI_02050 dusB tRNA dihydrouridine synthase DusB 0.35 BNILDI_21610 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
Marinobacter adhaerens HP15 0.31 HP15_3225 tRNA-dihydrouridine synthase B 0.34 HP15_2466 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 73
Escherichia coli ECRC101 0.31 OKFHMN_17685 dusB tRNA dihydrouridine synthase DusB 0.35 OKFHMN_07225 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
Escherichia coli BL21 0.31 ECD_03118 tRNA-dihydrouridine synthase B 0.35 ECD_00629 tRNA-i(6)A37 methylthiotransferase low > 60
Escherichia coli BW25113 0.31 b3260 dusB tRNA-dihydrouridine synthase B (NCBI) 0.35 b0661 miaB isopentenyl-adenosine A37 tRNA methylthiolase (NCBI) low > 76
Escherichia coli ECOR27 0.31 NOLOHH_09470 dusB tRNA dihydrouridine synthase DusB 0.35 NOLOHH_23605 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 57
Escherichia coli ECRC102 0.31 NIAGMN_15445 dusB tRNA dihydrouridine synthase DusB 0.35 NIAGMN_05280 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
Escherichia fergusonii Becca 0.31 EFB2_00564 tRNA-dihydrouridine synthase B 0.35 EFB2_03438 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 86
Escherichia coli ECOR38 0.31 HEPCGN_16505 dusB tRNA dihydrouridine synthase DusB 0.35 HEPCGN_01005 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 85
Escherichia coli Nissle 1917 0.31 ECOLIN_RS18725 tRNA dihydrouridine synthase DusB 0.35 ECOLIN_RS03555 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
Escherichia coli ECRC101 0.31 MCAODC_08205 dusB tRNA dihydrouridine synthase DusB 0.35 MCAODC_26440 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
Pectobacterium carotovorum WPP14 0.31 HER17_RS20235 tRNA dihydrouridine synthase DusB 0.34 HER17_RS15165 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 75
Lysobacter sp. OAE881 0.31 ABIE51_RS16450 tRNA dihydrouridine synthase DusB 0.35 ABIE51_RS15455 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 62
Rhodanobacter denitrificans MT42 0.31 LRK55_RS11875 tRNA dihydrouridine synthase DusB 0.35 LRK55_RS13465 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 63
Variovorax sp. OAS795 0.31 ABID97_RS24735 tRNA dihydrouridine synthase DusB 0.34 ABID97_RS06475 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF634 tRNA dihydrouridine synthase B (EC 1.-.-.-) 0.35 GFF613 tRNA-i(6)A37 methylthiotransferase low > 90
Rhodanobacter sp. FW510-T8 0.31 OKGIIK_11770 dusB tRNA dihydrouridine synthase DusB 0.33 OKGIIK_02990 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 52
Rhodanobacter denitrificans FW104-10B01 0.31 LRK54_RS12140 tRNA dihydrouridine synthase DusB 0.34 LRK54_RS13750 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 59
Pantoea sp. MT58 0.31 IAI47_02385 tRNA dihydrouridine synthase DusB 0.35 IAI47_13945 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 76
Shewanella loihica PV-4 0.30 Shew_0330 nifR3 family TIM-barrel protein (RefSeq) 0.33 Shew_2923 tRNA-i(6)A37 thiotransferase enzyme MiaB (RefSeq) low > 60
Azospirillum brasilense Sp245 0.30 AZOBR_RS14420 tRNA-dihydrouridine synthase 0.32 AZOBR_RS01475 (dimethylallyl)adenosine tRNA methylthiotransferase low > 97
Pseudomonas fluorescens GW456-L13 0.30 PfGW456L13_55 tRNA dihydrouridine synthase B (EC 1.-.-.-) 0.32 PfGW456L13_1380 tRNA-i(6)A37 methylthiotransferase low > 87
Pseudomonas fluorescens FW300-N2E3 0.30 AO353_13660 tRNA-dihydrouridine synthase B 0.32 AO353_06375 (dimethylallyl)adenosine tRNA methylthiotransferase low > 101
Acidovorax sp. GW101-3H11 0.30 Ac3H11_3996 tRNA dihydrouridine synthase B (EC 1.-.-.-) 0.35 Ac3H11_4008 tRNA-i(6)A37 methylthiotransferase low > 79
Pseudomonas fluorescens FW300-N2C3 0.30 AO356_08215 tRNA-dihydrouridine synthase B 0.33 AO356_15410 (dimethylallyl)adenosine tRNA methylthiotransferase low > 104
Pseudomonas fluorescens FW300-N1B4 0.29 Pf1N1B4_1313 tRNA dihydrouridine synthase B (EC 1.-.-.-) 0.32 Pf1N1B4_2712 tRNA-i(6)A37 methylthiotransferase low > 87
Pseudomonas sp. RS175 0.29 PFR28_05216 tRNA-dihydrouridine synthase B 0.32 PFR28_03848 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 88
Herbaspirillum seropedicae SmR1 0.29 HSERO_RS02050 tRNA-dihydrouridine synthase B 0.37 HSERO_RS03615 (dimethylallyl)adenosine tRNA methylthiotransferase low > 78
Pseudomonas fluorescens FW300-N2E2 0.29 Pf6N2E2_3517 tRNA dihydrouridine synthase B (EC 1.-.-.-) 0.32 Pf6N2E2_5018 tRNA-i(6)A37 methylthiotransferase low > 103
Vibrio cholerae E7946 ATCC 55056 0.29 CSW01_01495 tRNA dihydrouridine synthase DusB 0.32 CSW01_04915 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 62
Pseudomonas simiae WCS417 0.29 PS417_02950 tRNA-dihydrouridine synthase B 0.32 PS417_24625 (dimethylallyl)adenosine tRNA methylthiotransferase low > 88
Pseudomonas fluorescens SBW25-INTG 0.29 PFLU_RS03025 tRNA dihydrouridine synthase DusB 0.32 PFLU_RS26555 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 109
Escherichia coli ECRC98 0.29 JDDGAC_21310 dusB tRNA dihydrouridine synthase DusB 0.35 JDDGAC_10870 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
Escherichia coli ECRC99 0.29 KEDOAH_10465 dusB tRNA dihydrouridine synthase DusB 0.35 KEDOAH_20745 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
Pseudomonas fluorescens SBW25 0.29 PFLU_RS03025 tRNA dihydrouridine synthase DusB 0.32 PFLU_RS26555 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 109
Pseudomonas syringae pv. syringae B728a ΔmexB 0.29 Psyr_4404 tRNA-U20-dihydrouridine synthase 0.32 Psyr_4345 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 86
Rhodopseudomonas palustris CGA009 0.29 TX73_013410 tRNA dihydrouridine synthase DusB 0.28 TX73_002325 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 86
Pseudomonas syringae pv. syringae B728a 0.29 Psyr_4404 tRNA-U20-dihydrouridine synthase 0.32 Psyr_4345 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.28 OHPLBJKB_00445 putative tRNA-dihydrouridine synthase 0.35 OHPLBJKB_03051 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 73
Sphingomonas koreensis DSMZ 15582 0.28 Ga0059261_0140 tRNA-U20-dihydrouridine synthase 0.29 Ga0059261_1604 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB low > 68
Rhodospirillum rubrum S1H 0.28 Rru_A1676 Dihydrouridine synthase TIM-barrel protein nifR3 (NCBI) 0.32 Rru_A3770 tRNA-i(6)A37 modification enzyme MiaB (NCBI) low > 58
Caulobacter crescentus NA1000 Δfur 0.24 CCNA_01813 tRNA-dihydrouridine synthase 0.33 CCNA_00054 tRNA 2-methylthioadenosine synthase low > 67
Caulobacter crescentus NA1000 0.24 CCNA_01813 tRNA-dihydrouridine synthase 0.33 CCNA_00054 tRNA 2-methylthioadenosine synthase low > 66
Fusobacterium nucleatum SB010 0.23 HUW76_04330 tRNA-dihydrouridine synthase 0.34 HUW76_07655 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 35
Mycobacterium tuberculosis H37Rv 0.23 Rv0823c Possible transcriptional regulatory protein 0.31 Rv2733c Conserved hypothetical alanine, arginine-rich protein low > 58
Synechococcus elongatus PCC 7942 0.23 Synpcc7942_0283 Dihydrouridine synthase TIM-barrel protein nifR3 0.32 Synpcc7942_2374 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 38
Desulfovibrio vulgaris Miyazaki F 0.20 DvMF_2019 dihydrouridine synthase DuS (RefSeq) 0.28 DvMF_1330 RNA modification enzyme, MiaB family (RefSeq) low > 51
Bosea sp. OAE506 0.12 ABIE41_RS21285 tRNA dihydrouridine(20/20a) synthase DusA 0.32 ABIE41_RS04495 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 77

Not shown: 2 genomes with orthologs for BT3073 only; 15 genomes with orthologs for BT3195 only