Conservation of cofitness between b4006 and b3389 in Escherichia coli BW25113

89 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b4006 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) 1.0 b3389 aroB 3-dehydroquinate synthase (NCBI) 0.85 20
Escherichia coli BL21 1.00 ECD_03883 IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase 1.00 ECD_03241 3-dehydroquinate synthase low > 60
Escherichia coli ECRC99 1.00 KEDOAH_14850 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.99 KEDOAH_11025 aroB 3-dehydroquinate synthase — —
Escherichia coli ECRC101 1.00 OKFHMN_13310 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.99 OKFHMN_17115 aroB 3-dehydroquinate synthase — —
Escherichia coli ECRC101 1.00 MCAODC_03810 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.99 MCAODC_07645 aroB 3-dehydroquinate synthase — —
Escherichia coli ECRC98 1.00 JDDGAC_16935 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.99 JDDGAC_20745 aroB 3-dehydroquinate synthase — —
Escherichia coli ECRC102 1.00 NIAGMN_11060 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.99 NIAGMN_14885 aroB 3-dehydroquinate synthase — —
Escherichia coli ECOR27 1.00 NOLOHH_05455 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1.00 NOLOHH_08905 aroB 3-dehydroquinate synthase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_04043 Bifunctional purine biosynthesis protein PurH 0.99 OHPLBJKB_00314 3-dehydroquinate synthase low > 73
Escherichia coli ECRC62 0.99 BNILDI_06065 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1.00 BNILDI_02615 aroB 3-dehydroquinate synthase — —
Escherichia coli ECOR38 0.99 HEPCGN_11950 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1.00 HEPCGN_15935 aroB 3-dehydroquinate synthase low > 85
Escherichia fergusonii Becca 0.99 EFB2_04604 Bifunctional purine biosynthesis protein PurH 1.00 EFB2_00439 3-dehydroquinate synthase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS23100 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.99 ECOLIN_RS19360 3-dehydroquinate synthase low > 52
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF4186 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.86 GFF630 3-dehydroquinate synthase (EC 4.2.3.4) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS01615 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.85 BWI76_RS26085 3-dehydroquinate synthase 0.64 75
Enterobacter sp. TBS_079 0.94 MPMX20_00226 Bifunctional purine biosynthesis protein PurH 0.89 MPMX20_04278 3-dehydroquinate synthase 0.81 45
Enterobacter asburiae PDN3 0.94 EX28DRAFT_4545 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) 0.88 EX28DRAFT_4153 3-dehydroquinate synthase (EC 4.2.3.4) — —
Dickeya dadantii 3937 0.91 DDA3937_RS01220 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.81 DDA3937_RS19545 3-dehydroquinate synthase — —
Pectobacterium carotovorum WPP14 0.90 HER17_RS20335 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.79 HER17_RS01780 3-dehydroquinate synthase 0.88 57
Dickeya dianthicola ME23 0.90 DZA65_RS01260 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.80 DZA65_RS20760 3-dehydroquinate synthase — —
Dickeya dianthicola 67-19 0.90 HGI48_RS01215 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.80 HGI48_RS19675 3-dehydroquinate synthase — —
Pantoea sp. MT58 0.90 IAI47_18040 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.84 IAI47_01895 3-dehydroquinate synthase — —
Serratia liquefaciens MT49 0.89 IAI46_01365 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.81 IAI46_23700 3-dehydroquinate synthase 0.48 81
Rahnella sp. WP5 0.88 EX31_RS16860 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.84 EX31_RS04720 3-dehydroquinate synthase — —
Erwinia tracheiphila SCR3 0.88 LU632_RS01020 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.82 LU632_RS22865 aroB 3-dehydroquinate synthase 0.54 45
Vibrio cholerae E7946 ATCC 55056 0.81 CSW01_01420 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.63 CSW01_13300 3-dehydroquinate synthase low > 62
Shewanella loihica PV-4 0.77 Shew_3412 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.60 Shew_0214 3-dehydroquinate synthase (RefSeq) 0.77 43
Alteromonas macleodii MIT1002 0.76 MIT1002_03959 Bifunctional purine biosynthesis protein PurH 0.60 MIT1002_00447 3-dehydroquinate synthase — —
Shewanella amazonensis SB2B 0.76 Sama_0395 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.62 Sama_3367 3-dehydroquinate synthase (RefSeq) low > 62
Shewanella sp. ANA-3 0.74 Shewana3_0441 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.61 Shewana3_3893 aroB 3-dehydroquinate synthase (RefSeq) 0.92 21
Shewanella oneidensis MR-1 0.73 SO0442 purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI ptt file) 0.61 SO0287 aroB 3-dehydroquinate synthase (NCBI ptt file) 0.85 76
Marinobacter adhaerens HP15 0.72 HP15_3227 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.53 HP15_480 3-dehydroquinate synthase — —
Kangiella aquimarina DSM 16071 0.71 B158DRAFT_0166 IMP cyclohydrolase (EC 3.5.4.10)/phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.44 B158DRAFT_0764 3-dehydroquinate synthase (EC 4.2.3.4) — —
Pseudomonas fluorescens FW300-N1B4 0.70 Pf1N1B4_1315 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.55 Pf1N1B4_1537 3-dehydroquinate synthase (EC 4.2.3.4) — —
Pseudomonas sp. S08-1 0.69 OH686_07620 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.54 OH686_10015 3-dehydroquinate synthase — —
Pseudomonas fluorescens FW300-N2C3 0.69 AO356_08225 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.55 AO356_09385 3-dehydroquinate synthase — —
Pseudomonas fluorescens FW300-N2E2 0.69 Pf6N2E2_3519 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.55 Pf6N2E2_3754 3-dehydroquinate synthase (EC 4.2.3.4) — —
Pseudomonas sp. RS175 0.69 PFR28_05214 Bifunctional purine biosynthesis protein PurH 0.54 PFR28_05013 3-dehydroquinate synthase — —
Pseudomonas fluorescens GW456-L13 0.69 PfGW456L13_57 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.55 PfGW456L13_275 3-dehydroquinate synthase (EC 4.2.3.4) — —
Pseudomonas fluorescens SBW25-INTG 0.69 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.55 PFLU_RS02030 3-dehydroquinate synthase — —
Pseudomonas fluorescens SBW25 0.69 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.55 PFLU_RS02030 3-dehydroquinate synthase — —
Acinetobacter radioresistens SK82 0.69 MPMX26_01141 Bifunctional purine biosynthesis protein PurH 0.50 MPMX26_02810 3-dehydroquinate synthase — —
Pseudomonas fluorescens FW300-N2E3 0.69 AO353_13650 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.54 AO353_12505 3-dehydroquinate synthase — —
Pseudomonas simiae WCS417 0.69 PS417_02940 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.55 PS417_01985 3-dehydroquinate synthase — —
Pseudomonas putida KT2440 0.68 PP_4822 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.55 PP_5078 3-dehydroquinate synthase — —
Pseudomonas stutzeri RCH2 0.68 Psest_1014 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.53 Psest_3713 3-dehydroquinate synthase — —
Pseudomonas syringae pv. syringae B728a 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase 0.54 Psyr_0409 3-dehydroquinate synthase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase 0.54 Psyr_0409 3-dehydroquinate synthase — —
Dyella japonica UNC79MFTsu3.2 0.61 ABZR86_RS17045 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.42 ABZR86_RS10480 3-dehydroquinate synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.61 H281DRAFT_04251 IMP cyclohydrolase /phosphoribosylaminoimidazolecarboxamide formyltransferase 0.51 H281DRAFT_05615 3-dehydroquinate synthase — —
Paraburkholderia graminis OAS925 0.61 ABIE53_003491 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.52 ABIE53_003740 3-dehydroquinate synthase — —
Burkholderia phytofirmans PsJN 0.60 BPHYT_RS16595 bifunctional purine biosynthesis protein PurH 0.52 BPHYT_RS17885 3-dehydroquinate synthase — —
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS26780 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.51 QEN71_RS28035 3-dehydroquinate synthase 0.44 69
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS07640 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.50 ABZR87_RS02590 3-dehydroquinate synthase — —
Ralstonia solanacearum PSI07 0.59 RPSI07_RS21530 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.50 RPSI07_RS10300 3-dehydroquinate synthase — —
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS02720 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.52 RR42_RS19005 3-dehydroquinate synthase — —
Ralstonia solanacearum UW163 0.59 UW163_RS01900 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.50 UW163_RS06680 3-dehydroquinate synthase — —
Ralstonia solanacearum IBSBF1503 0.59 RALBFv3_RS11685 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.50 RALBFv3_RS06935 3-dehydroquinate synthase — —
Rhodanobacter denitrificans MT42 0.59 LRK55_RS06570 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.41 LRK55_RS04085 3-dehydroquinate synthase — —
Ralstonia solanacearum GMI1000 0.59 RS_RS02505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.51 RS_RS14880 3-dehydroquinate synthase — —
Rhodanobacter denitrificans FW104-10B01 0.58 LRK54_RS06825 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.41 LRK54_RS04310 3-dehydroquinate synthase — —
Rhodanobacter sp. FW510-T8 0.58 OKGIIK_16805 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.42 OKGIIK_11185 aroB 3-dehydroquinate synthase — —
Lysobacter sp. OAE881 0.57 ABIE51_RS17760 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.41 ABIE51_RS16100 3-dehydroquinate synthase — —
Xanthomonas campestris pv. campestris strain 8004 0.56 Xcc-8004.659.1 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.41 Xcc-8004.1615.1 3-dehydroquinate synthase (EC 4.2.3.4) 0.57 16
Hydrogenophaga sp. GW460-11-11-14-LB1 0.56 GFF636 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.50 GFF1331 3-dehydroquinate synthase (EC 4.2.3.4) — —
Variovorax sp. SCN45 0.55 GFF2146 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.49 GFF5325 3-dehydroquinate synthase (EC 4.2.3.4) — —
Variovorax sp. OAS795 0.55 ABID97_RS24725 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.53 ABID97_RS23255 3-dehydroquinate synthase — —
Acidovorax sp. GW101-3H11 0.54 Ac3H11_3994 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.50 Ac3H11_4705 3-dehydroquinate synthase (EC 4.2.3.4) — —
Castellaniella sp019104865 MT123 0.54 ABCV34_RS07970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.46 ABCV34_RS12705 3-dehydroquinate synthase — —
Dechlorosoma suillum PS 0.54 Dsui_1595 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.53 Dsui_1095 3-dehydroquinate synthase — —
Azospirillum sp. SherDot2 0.54 MPMX19_02325 Bifunctional purine biosynthesis protein PurH 0.37 MPMX19_02639 3-dehydroquinate synthase — —
Phaeobacter inhibens DSM 17395 0.52 PGA1_c32860 bifunctional purine biosynthesis protein PurH 0.38 PGA1_c14100 3-dehydroquinate synthase AroB — —
Rhodopseudomonas palustris CGA009 0.52 TX73_000145 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.37 TX73_002610 3-dehydroquinate synthase — —
Azospirillum brasilense Sp245 0.51 AZOBR_RS00225 purine biosynthesis protein purH 0.38 AZOBR_RS03220 3-dehydroquinate synthase — —
Dinoroseobacter shibae DFL-12 0.50 Dshi_0358 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.36 Dshi_1608 3-dehydroquinate synthase (RefSeq) — —
Sphingomonas koreensis DSMZ 15582 0.49 Ga0059261_2242 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.36 Ga0059261_3591 3-dehydroquinate synthase (EC 4.2.3.4) — —
Magnetospirillum magneticum AMB-1 0.49 AMB_RS00505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.40 AMB_RS19865 3-dehydroquinate synthase — —
Rhodospirillum rubrum S1H 0.49 Rru_A3655 Phosphoribosylaminoimidazolecarboxamideformyltransferase (NCBI) 0.41 Rru_A3741 3-dehydroquinate synthase (NCBI) — —
Sinorhizobium meliloti 1021 0.47 SMc04088 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.38 SMc00696 3-dehydroquinate synthase — —
Rhizobium sp. OAE497 0.47 ABIE40_RS19130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.38 ABIE40_RS17670 3-dehydroquinate synthase — —
Caulobacter crescentus NA1000 Δfur 0.47 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.41 CCNA_03104 3-dehydroquinate synthase low > 67
Caulobacter crescentus NA1000 0.47 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.41 CCNA_03104 3-dehydroquinate synthase 0.87 38
Agrobacterium fabrum C58 0.46 Atu2823 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.38 Atu3625 3-dehydroquinate synthase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.44 A4249_RS13150 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.38 A4249_RS04175 3-dehydroquinate synthase — —
Synechococcus elongatus PCC 7942 0.42 Synpcc7942_0396 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.40 Synpcc7942_0525 aroB 3-dehydroquinate synthase — —
Mycobacterium tuberculosis H37Rv 0.40 Rv0957 Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC) 0.29 Rv2538c 3-dehydroquinate synthase AroB — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.35 ABZR88_RS16970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.25 ABZR88_RS05215 3-dehydroquinate synthase — —
Bacteroides ovatus ATCC 8483 0.35 BACOVA_03657 putative phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.21 BACOVA_04629 3-dehydroquinate synthase — —
Bacteroides stercoris CC31F 0.35 HMPREF1181_RS00165 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.21 HMPREF1181_RS09265 3-dehydroquinate synthase low > 56
Pontibacter actiniarum KMM 6156, DSM 19842 0.34 CA264_18630 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.22 CA264_13105 3-dehydroquinate synthase — —

Not shown: 10 genomes with orthologs for b4006 only; 0 genomes with orthologs for b3389 only