| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b2025 | hisF | imidazole glycerol phosphate synthase subunit HisF (NCBI) | 1.0 | b3281 | aroE | dehydroshikimate reductase, NAD(P)-binding (NCBI) | 0.93 | 19 |
| Escherichia coli ECRC101 | 1.00 | MCAODC_20450 | hisF | Imidazole glycerol phosphate synthase subunit HisF | 0.98 | MCAODC_08085 | aroE | shikimate dehydrogenase | — | — |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_03660 | hisF | Imidazole glycerol phosphate synthase subunit HisF | 0.98 | KEDOAH_10585 | aroE | shikimate dehydrogenase | — | — |
| Escherichia fergusonii Becca | 1.00 | EFB2_01831 | | Imidazole glycerol phosphate synthase subunit HisF | 0.96 | EFB2_00542 | | Shikimate dehydrogenase (NADP(+)) | low | > 86 |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_28600 | hisF | Imidazole glycerol phosphate synthase subunit HisF | 0.98 | JDDGAC_21185 | aroE | shikimate dehydrogenase | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_22435 | hisF | Imidazole glycerol phosphate synthase subunit HisF | 0.98 | NIAGMN_15325 | aroE | shikimate dehydrogenase | — | — |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_24490 | hisF | Imidazole glycerol phosphate synthase subunit HisF | 0.98 | OKFHMN_17565 | aroE | shikimate dehydrogenase | — | — |
| Escherichia coli ECRC62 | 1.00 | BNILDI_14715 | hisF | Imidazole glycerol phosphate synthase subunit HisF | 0.99 | BNILDI_02165 | aroE | shikimate dehydrogenase | — | — |
| Escherichia coli Nissle 1917 | 1.00 | ECOLIN_RS11970 | | imidazole glycerol phosphate synthase subunit HisF | 0.97 | ECOLIN_RS18840 | | shikimate dehydrogenase | low | > 52 |
| Escherichia coli ECOR38 | 0.99 | HEPCGN_03195 | hisF | Imidazole glycerol phosphate synthase subunit HisF | 0.97 | HEPCGN_16385 | aroE | shikimate dehydrogenase | low | > 85 |
| Escherichia coli ECOR27 | 0.99 | NOLOHH_15805 | hisF | Imidazole glycerol phosphate synthase subunit HisF | 0.99 | NOLOHH_09355 | aroE | shikimate dehydrogenase | low | > 57 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.99 | OHPLBJKB_01675 | | Imidazole glycerol phosphate synthase subunit HisF | 1.00 | OHPLBJKB_00422 | | Shikimate dehydrogenase (NADP(+)) | low | > 73 |
| Escherichia coli BL21 | 0.99 | ECD_01927 | | imidazole glycerol phosphate synthase, catalytic subunit with HisH | 1.00 | ECD_03132 | | dehydroshikimate reductase, NAD(P)-binding | — | — |
| Enterobacter sp. TBS_079 | 0.97 | MPMX20_03007 | | Imidazole glycerol phosphate synthase subunit HisF | 0.82 | MPMX20_04189 | | Shikimate dehydrogenase (NADP(+)) | 0.88 | 39 |
| Enterobacter asburiae PDN3 | 0.96 | EX28DRAFT_0534 | | imidazoleglycerol phosphate synthase, cyclase subunit | 0.81 | EX28DRAFT_0046 | | shikimate dehydrogenase | low | > 76 |
| Klebsiella michiganensis M5al | 0.96 | BWI76_RS18950 | | imidazole glycerol phosphate synthase cyclase subunit | 0.81 | BWI76_RS25645 | | shikimate dehydrogenase | 0.75 | 60 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.95 | GFF3907 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | 0.87 | GFF2397 | | Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) | low | > 78 |
| Serratia liquefaciens MT49 | 0.95 | IAI46_08185 | | imidazole glycerol phosphate synthase subunit HisF | 0.66 | IAI46_23240 | | shikimate dehydrogenase | low | > 86 |
| Dickeya dadantii 3937 | 0.93 | DDA3937_RS09710 | | imidazole glycerol phosphate synthase subunit HisF | 0.61 | DDA3937_RS19100 | | shikimate dehydrogenase | — | — |
| Erwinia tracheiphila SCR3 | 0.93 | LU632_RS08920 | hisF | imidazole glycerol phosphate synthase subunit HisF | 0.64 | LU632_RS22445 | aroE | shikimate dehydrogenase | low | > 74 |
| Dickeya dianthicola 67-19 | 0.92 | HGI48_RS09720 | | imidazole glycerol phosphate synthase subunit HisF | 0.61 | HGI48_RS19190 | | shikimate dehydrogenase | — | — |
| Dickeya dianthicola ME23 | 0.92 | DZA65_RS10030 | | imidazole glycerol phosphate synthase subunit HisF | 0.60 | DZA65_RS20315 | | shikimate dehydrogenase | — | — |
| Pectobacterium carotovorum WPP14 | 0.91 | HER17_RS12255 | | imidazole glycerol phosphate synthase subunit HisF | 0.62 | HER17_RS02250 | | shikimate dehydrogenase | 0.96 | 27 |
| Rahnella sp. WP5 | 0.91 | EX31_RS11465 | | imidazole glycerol phosphate synthase subunit HisF | 0.62 | EX31_RS15950 | | shikimate dehydrogenase | — | — |
| Pantoea sp. MT58 | 0.90 | IAI47_07065 | | imidazole glycerol phosphate synthase subunit HisF | 0.66 | IAI47_02315 | | shikimate dehydrogenase | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.87 | CSW01_05775 | | imidazole glycerol phosphate synthase cyclase subunit | 0.49 | CSW01_00280 | | shikimate dehydrogenase | low | > 62 |
| Shewanella amazonensis SB2B | 0.77 | Sama_1947 | | imidazole glycerol phosphate synthase subunit HisF (RefSeq) | 0.43 | Sama_0052 | | shikimate dehydrogenase (RefSeq) | low | > 62 |
| Alteromonas macleodii MIT1002 | 0.76 | MIT1002_02638 | | Imidazole glycerol phosphate synthase subunit HisF | 0.31 | MIT1002_00029 | | Shikimate dehydrogenase | — | — |
| Shewanella oneidensis MR-1 | 0.75 | SO2068 | hisF | hisF protein (cyclase) (NCBI ptt file) | 0.48 | SO0040 | aroE | shikimate 5-dehydrogenase (NCBI ptt file) | 0.87 | 65 |
| Shewanella sp. ANA-3 | 0.75 | Shewana3_1848 | | imidazole glycerol phosphate synthase subunit HisF (RefSeq) | 0.48 | Shewana3_0043 | aroE | shikimate 5-dehydrogenase (RefSeq) | 0.89 | 46 |
| Shewanella loihica PV-4 | 0.75 | Shew_2203 | | imidazole glycerol phosphate synthase subunit HisF (RefSeq) | 0.47 | Shew_3727 | | shikimate 5-dehydrogenase (RefSeq) | low | > 60 |
| Lysobacter sp. OAE881 | 0.65 | ABIE51_RS13300 | | imidazole glycerol phosphate synthase subunit HisF | 0.31 | ABIE51_RS01815 | | shikimate dehydrogenase | low | > 62 |
| Rhodanobacter denitrificans FW104-10B01 | 0.65 | LRK54_RS01580 | | imidazole glycerol phosphate synthase subunit HisF | 0.33 | LRK54_RS08595 | | shikimate dehydrogenase | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.64 | LRK55_RS01360 | | imidazole glycerol phosphate synthase subunit HisF | 0.33 | LRK55_RS08360 | | shikimate dehydrogenase | low | > 63 |
| Rhodanobacter sp. FW510-T8 | 0.64 | OKGIIK_04975 | hisF | imidazole glycerol phosphate synthase subunit HisF | 0.32 | OKGIIK_15365 | aroE | shikimate dehydrogenase | low | > 52 |
| Dyella japonica UNC79MFTsu3.2 | 0.63 | ABZR86_RS06705 | | imidazole glycerol phosphate synthase subunit HisF | 0.33 | ABZR86_RS14985 | | shikimate dehydrogenase | 0.92 | 26 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.63 | Xcc-8004.2943.1 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | 0.33 | Xcc-8004.5020.1 | | Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) | 0.89 | 11 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.57 | A4249_RS10715 | | imidazole glycerol phosphate synthase subunit HisF | 0.18 | A4249_RS13660 | | shikimate dehydrogenase | — | — |
| Phocaeicola vulgatus CL09T03C04 | 0.46 | HMPREF1058_RS06175 | | imidazole glycerol phosphate synthase subunit HisF | 0.16 | HMPREF1058_RS16750 | | shikimate dehydrogenase | low | > 67 |
| Phocaeicola dorei CL03T12C01 | 0.46 | ABI39_RS19930 | | imidazole glycerol phosphate synthase subunit HisF | 0.16 | ABI39_RS12665 | | shikimate dehydrogenase | 0.78 | 28 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.44 | BT1378 | | imidazole glycerol phosphate synthase subunit hisF (NCBI ptt file) | 0.17 | BT4215 | | shikimate dehydrogenase (EC 1.1.1.25) (from data) | — | — |
| Bacteroides ovatus ATCC 8483 | 0.44 | BACOVA_00219 | | imidazoleglycerol phosphate synthase, cyclase subunit | 0.17 | BACOVA_05065 | | putative shikimate dehydrogenase | — | — |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.43 | ABZR88_RS06855 | | imidazole glycerol phosphate synthase subunit HisF | 0.14 | ABZR88_RS20055 | | shikimate dehydrogenase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.43 | RALBFv3_RS06815 | | imidazole glycerol phosphate synthase subunit HisF | 0.37 | RALBFv3_RS05945 | | shikimate dehydrogenase | — | — |
| Ralstonia solanacearum UW163 | 0.43 | UW163_RS06800 | | imidazole glycerol phosphate synthase subunit HisF | 0.37 | UW163_RS07680 | | shikimate dehydrogenase | — | — |
| Ralstonia solanacearum PSI07 | 0.42 | RPSI07_RS10420 | | imidazole glycerol phosphate synthase subunit HisF | 0.37 | RPSI07_RS11300 | | shikimate dehydrogenase | — | — |
| Pseudomonas sp. S08-1 | 0.42 | OH686_14595 | | Imidazole glycerol phosphate synthase cyclase subunit | 0.48 | OH686_12485 | | Shikimate 5-dehydrogenase I alpha | 0.63 | 41 |
| Ralstonia solanacearum GMI1000 | 0.42 | RS_RS14760 | | imidazole glycerol phosphate synthase subunit HisF | 0.37 | RS_RS13890 | | shikimate dehydrogenase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.42 | ABZR87_RS02470 | | imidazole glycerol phosphate synthase subunit HisF | 0.39 | ABZR87_RS01605 | | shikimate dehydrogenase | — | — |
| Pseudomonas stutzeri RCH2 | 0.42 | Psest_0156 | | imidazoleglycerol phosphate synthase, cyclase subunit | 0.47 | Psest_0029 | | shikimate 5-dehydrogenase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.42 | RR42_RS18885 | | imidazole glycerol phosphate synthase | 0.37 | RR42_RS17645 | | shikimate dehydrogenase | — | — |
| Bacteroides stercoris CC31F | 0.42 | HMPREF1181_RS11070 | | imidazole glycerol phosphate synthase subunit HisF | 0.17 | HMPREF1181_RS06320 | | shikimate dehydrogenase | 0.85 | 50 |
| Caulobacter crescentus NA1000 | 0.41 | CCNA_03853 | | imidazole glycerol phosphate synthase, cyclase subunit | 0.19 | CCNA_00003 | | shikimate dehydrogenase (EC 1.1.1.25) (from data) | 0.88 | 49 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.41 | Echvi_2516 | | imidazoleglycerol phosphate synthase, cyclase subunit | 0.15 | Echvi_1145 | | Shikimate 5-dehydrogenase | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.41 | CCNA_03853 | | imidazole glycerol phosphate synthase, cyclase subunit | 0.19 | CCNA_00003 | | shikimate 5-dehydrogenase | low | > 67 |
| Burkholderia phytofirmans PsJN | 0.41 | BPHYT_RS17680 | | imidazole glycerol phosphate synthase subunit HisF | 0.40 | BPHYT_RS16975 | | shikimate 5-dehydrogenase | 0.67 | 56 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.41 | H281DRAFT_05659 | | imidazole glycerol phosphate synthase subunit hisF | 0.40 | H281DRAFT_01679 | | shikimate dehydrogenase (EC 1.1.1.25) | — | — |
| Pseudomonas putida KT2440 | 0.41 | PP_0293 | | Imidazole glycerol phosphate synthase subunit HisF | 0.45 | PP_0074 | | shikimate 5-dehydrogenase | — | — |
| Paraburkholderia graminis OAS925 | 0.41 | ABIE53_003695 | | cyclase | 0.41 | ABIE53_003560 | | shikimate dehydrogenase | — | — |
| Variovorax sp. OAS795 | 0.41 | ABID97_RS23105 | | imidazole glycerol phosphate synthase subunit HisF | 0.29 | ABID97_RS06300 | | shikimate dehydrogenase | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.40 | QEN71_RS27835 | | imidazole glycerol phosphate synthase subunit HisF | 0.43 | QEN71_RS27130 | | shikimate dehydrogenase | 0.71 | 69 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.40 | Psyr_4893 | | imidazole glycerol phosphate synthase subunit hisF | 0.49 | Psyr_0025 | | shikimate dehydrogenase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.40 | Psyr_4893 | | imidazole glycerol phosphate synthase subunit hisF | 0.49 | Psyr_0025 | | shikimate dehydrogenase | 0.50 | 69 |
| Pseudomonas sp. RS175 | 0.40 | PFR28_04933 | | Imidazole glycerol phosphate synthase subunit HisF | 0.50 | PFR28_04655 | | Shikimate dehydrogenase (NADP(+)) | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.40 | Pf1N1B4_1623 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | 0.50 | Pf1N1B4_1906 | | Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.40 | Pf6N2E2_3838 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | 0.49 | Pf6N2E2_4130 | | Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.40 | PFLU_RS01625 | | imidazole glycerol phosphate synthase subunit HisF | 0.47 | PFLU_RS00120 | | shikimate dehydrogenase | — | — |
| Azospirillum sp. SherDot2 | 0.40 | MPMX19_02542 | | Imidazole glycerol phosphate synthase subunit HisF | 0.21 | MPMX19_02560 | | Shikimate dehydrogenase (NADP(+)) | — | — |
| Pseudomonas fluorescens SBW25 | 0.40 | PFLU_RS01625 | | imidazole glycerol phosphate synthase subunit HisF | 0.47 | PFLU_RS00120 | | shikimate dehydrogenase | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.40 | AO356_09795 | | imidazole glycerol phosphate synthase subunit HisF | 0.49 | AO356_11315 | | shikimate dehydrogenase | 0.55 | 50 |
| Acinetobacter radioresistens SK82 | 0.40 | MPMX26_02854 | | Imidazole glycerol phosphate synthase subunit HisF | 0.40 | MPMX26_02748 | | Shikimate dehydrogenase (NADP(+)) | low | > 36 |
| Pseudomonas fluorescens FW300-N2E3 | 0.40 | AO353_12090 | | imidazole glycerol phosphate synthase subunit HisF | 0.49 | AO353_10670 | | shikimate dehydrogenase | 0.67 | 43 |
| Pseudomonas fluorescens GW456-L13 | 0.40 | PfGW456L13_358 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | 0.48 | PfGW456L13_644 | | Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) | 0.71 | 55 |
| Pseudomonas simiae WCS417 | 0.40 | PS417_01580 | | imidazole glycerol phosphate synthase | 0.48 | PS417_00125 | | shikimate dehydrogenase | — | — |
| Kangiella aquimarina DSM 16071 | 0.39 | B158DRAFT_2291 | | imidazoleglycerol phosphate synthase, cyclase subunit | 0.30 | B158DRAFT_0259 | | shikimate 5-dehydrogenase | low | > 40 |
| Herbaspirillum seropedicae SmR1 | 0.39 | HSERO_RS20315 | | imidazole glycerol phosphate synthase | 0.44 | HSERO_RS01990 | | shikimate 5-dehydrogenase | 0.64 | 43 |
| Variovorax sp. SCN45 | 0.39 | GFF5357 | | Imidazole glycerol phosphate synthase cyclase subunit | 0.32 | GFF4456 | | Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) | — | — |
| Marinobacter adhaerens HP15 | 0.39 | HP15_3009 | | protein containing histidine biosynthesis, HisF domain | 0.41 | HP15_3750 | | shikimate dehydrogenase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.38 | GFF1309 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | 0.41 | GFF5226 | | Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) | — | — |
| Dechlorosoma suillum PS | 0.38 | Dsui_1418 | | imidazoleglycerol phosphate synthase, cyclase subunit | 0.48 | Dsui_0443 | | shikimate 5-dehydrogenase | — | — |
| Castellaniella sp019104865 MT123 | 0.37 | ABCV34_RS11250 | | imidazole glycerol phosphate synthase subunit HisF | 0.39 | ABCV34_RS11620 | | shikimate dehydrogenase | low | > 48 |
| Dinoroseobacter shibae DFL-12 | 0.37 | Dshi_2576 | | imidazoleglycerol phosphate synthase, cyclase subunit (RefSeq) | 0.25 | Dshi_3450 | | shikimate 5-dehydrogenase (RefSeq) | — | — |
| Agrobacterium fabrum C58 | 0.37 | Atu0039 | | imidazoleglycerol-phosphate synthase cyclase | 0.24 | Atu0003 | | shikimate 5-dehydrogenase | — | — |
| Sinorhizobium meliloti 1021 | 0.36 | SMc02569 | | imidazole glycerol phosphate synthase subunit HisF | 0.23 | SMc02791 | | shikimate 5-dehydrogenase | — | — |
| Rhodospirillum rubrum S1H | 0.36 | Rru_A3594 | | Histidine biosynthesis protein HisF (NCBI) | 0.22 | Rru_A3613 | | Quinate/Shikimate 5-dehydrogenase (NCBI) | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.35 | Ga0059261_1048 | | imidazoleglycerol phosphate synthase, cyclase subunit | 0.17 | Ga0059261_2194 | | shikimate dehydrogenase (EC 1.1.1.25) (from data) | 0.92 | 46 |
| Acidovorax sp. GW101-3H11 | 0.34 | Ac3H11_4733 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | 0.32 | Ac3H11_4044 | | Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) | — | — |
| Bosea sp. OAE506 | 0.34 | ABIE41_RS03810 | | imidazole glycerol phosphate synthase subunit HisF | 0.19 | ABIE41_RS04650 | | shikimate dehydrogenase | — | — |
| Phaeobacter inhibens DSM 17395 | 0.34 | PGA1_c09240 | | imidazole glycerol phosphate synthase subunit HisF | 0.23 | PGA1_c35150 | | shikimate dehydrogenase AroE | — | — |
| Rhodopseudomonas palustris CGA009 | 0.33 | TX73_001625 | | imidazole glycerol phosphate synthase subunit HisF | 0.22 | TX73_022410 | | shikimate dehydrogenase | — | — |
Not shown: 12 genomes with orthologs for b2025 only; 1 genomes with orthologs for b3281 only