| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Mycobacterium tuberculosis H37Rv | Rv0981 | | Mycobacterial persistence regulator MRPA (two component response transcriptional regulatory protein) | insig. | 100 | 100 |
| | Mycobacterium tuberculosis H37Rv | Rv1033c | | Two component transcriptional regulator TrcR | insig. | 50 | 100 |
| o | Synechococcus elongatus PCC 7942 | Synpcc7942_1873 | | two component transcriptional regulator, winged helix family | insig. | 48 | 99 |
| o | Synechocystis sp000284455 PCC 6803 | SGL_RS14385 | | response regulator transcription factor | strong | 48 | 98 |
| | Mycobacterium tuberculosis H37Rv | Rv0757 | | Possible two component system response transcriptional positive regulator PhoP | sig. | 49 | 98 |
| o | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2622 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 48 | 98 |
| o | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS04655 | | DNA-binding response regulator | strong | 42 | 98 |
| | Mycobacterium tuberculosis H37Rv | Rv0903c | | Two component response transcriptional regulatory protein PrrA | no data | 50 | 92 |
| o | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS15000 | | response regulator transcription factor | strong | 42 | 98 |
| o | Pseudomonas stutzeri RCH2 | Psest_3476 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | insig. | 48 | 98 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_2305 | nblR | two component transcriptional regulator, winged helix family | strong | 47 | 99 |
| o | Pseudomonas sp. SVBP6 | COO64_RS20755 | | response regulator | insig. | 45 | 100 |
| o | Pseudomonas segetis P6 | ACVTMO_RS18500 | | response regulator transcription factor | strong | 46 | 98 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS09450 | | response regulator transcription factor | insig. | 41 | 98 |
| o | Dechlorosoma suillum PS | Dsui_2644 | | heavy metal response regulator | cofit | 46 | 99 |
| | Bifidobacterium breve UCC2003 | BBR_RS17455 | | DNA-binding response regulator | strong | 43 | 98 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_2416 | srrA | two component transcriptional regulator, winged helix family | sig. | 49 | 96 |
| o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1539 | | Two-component system response regulator QseB | insig. | 44 | 99 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_11860 | | copper response regulator transcription factor CusR | insig. | 45 | 100 |
| o | Klebsiella pneumoniae MRSN742743 | GJGHJB_04406 | cusR | copper response regulator transcription factor CusR | insig. | 45 | 100 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_23845 | | XRE family transcriptional regulator | insig. | 44 | 99 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_1165 | | heavy metal response regulator | insig. | 45 | 100 |
| o | Pseudomonas sp. S08-1 | OH686_04665 | | Two-component system response regulator QseB | insig. | 45 | 99 |
| o | Pseudomonas sp. RS175 | PFR28_02328 | | Transcriptional regulatory protein QseB | sig. | 43 | 99 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_02615 | | DNA-binding response regulator | sig. | 40 | 99 |
| | Variovorax sp. SCN45 | GFF4042 | | Copper-sensing two-component system response regulator CusR | insig. | 44 | 98 |
| o | Pseudomonas fluorescens GW456-L13 | PfGW456L13_3169 | | Two-component system response regulator QseB | insig. | 44 | 99 |
| o | Dickeya dianthicola 67-19 | HGI48_RS03485 | | heavy metal response regulator transcription factor | insig. | 44 | 100 |
| o | Pseudomonas simiae WCS417 | PS417_13595 | | XRE family transcriptional regulator | insig. | 44 | 99 |
| o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_04180 | | two component transcriptional regulator, winged helix family | sig. | 45 | 98 |
| o | Pseudomonas sp. DMC3 | GFF3603 | | Transcriptional regulatory protein QseB | cofit | 44 | 99 |
| o | Rhodospirillum rubrum S1H | Rru_A0603 | | Two component Transcriptional regulator, Winged helix family (NCBI) | cofit | 44 | 99 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_67 | | Copper-sensing two-component system response regulator CusR | no data | 45 | 100 |
| o | Dickeya dianthicola ME23 | DZA65_RS03595 | | copper/silver response regulator transcription factor SilR | insig. | 44 | 100 |
| o | Pseudomonas protegens RBAN4 | FABNJH_10290 | | DNA-binding copper response regulator | insig. | 45 | 99 |
| | Mycobacterium tuberculosis H37Rv | Rv3765c | | Probable two component transcriptional regulatory protein TcrX | insig. | 45 | 98 |
| o | Pseudomonas sp. BP01 | JOY50_RS08590 | | heavy metal response regulator transcription factor | insig. | 45 | 98 |
| | Variovorax sp. SCN45 | GFF11 | | Two-component transcriptional response regulator, OmpR family | insig. | 45 | 98 |
| o | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS20860 | | DNA-binding response regulator | insig. | 45 | 99 |
| o | Ralstonia solanacearum UW163 | UW163_RS21995 | | DNA-binding response regulator | insig. | 45 | 99 |
| o | Serratia liquefaciens MT49 | IAI46_16745 | | heavy metal response regulator transcription factor | insig. | 44 | 100 |
| | Fusobacterium nucleatum SB010 | HUW76_07205 | | response regulator transcription factor | strong | 40 | 99 |
| o | Ralstonia solanacearum GMI1000 | RS_RS20255 | | DNA-binding response regulator | insig. | 46 | 99 |
| | Variovorax sp. SCN45 | GFF4686 | | Copper-sensing two-component system response regulator CusR | insig. | 46 | 99 |
| o | Pseudomonas aeruginosa MRSN321 | PFGADD_02176 | copR | Two-component response regulator CopR | strong | 45 | 99 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_14215 | | DNA-binding response regulator | insig. | 45 | 99 |
| o | Pseudomonas aeruginosa PUPa3 | NPBIFN_02216 | copR | Two-component response regulator CopR | sig. | 45 | 99 |
| o | Paraburkholderia graminis OAS925 | ABIE53_003418 | | two-component system response regulator QseB | strong | 45 | 98 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4454 | | Two-component system response regulator QseB | no data | 43 | 99 |
| o | Burkholderia phytofirmans PsJN | BPHYT_RS16220 | | transcriptional regulator | no data | 45 | 98 |
| | Pseudomonas sp. S08-1 | OH686_22680 | | Copper-sensing two-component system response regulator CusR | strong | 45 | 98 |
| o | Pseudomonas putida KT2440 | PP_5383 | | transcriptional activator protein | insig. | 45 | 98 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1497 | | Heavy metal response regulator | insig. | 44 | 98 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1497 | | Heavy metal response regulator | insig. | 44 | 98 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_00355 | | transcriptional regulator | insig. | 44 | 100 |
| o | Ralstonia solanacearum PSI07 | RPSI07_RS02355 | | DNA-binding response regulator | insig. | 46 | 99 |
| | Pseudomonas sp. DMC3 | GFF1296 | | Transcriptional activator protein CopR | insig. | 44 | 99 |
| | Pseudomonas sp. SVBP6 | COO64_RS09510 | | heavy metal response regulator transcription factor | insig. | 44 | 99 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4017 | | Copper-sensing two-component system response regulator CusR | insig. | 45 | 100 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3127 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | sig. | 43 | 98 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3127 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | insig. | 43 | 98 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS15245 | | response regulator | insig. | 43 | 99 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15245 | | response regulator | insig. | 43 | 99 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS03060 | | DNA-binding response regulator | insig. | 40 | 99 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01669 | | Transcriptional activator protein CopR | cofit | 44 | 99 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS15305 | | heavy metal response regulator transcription factor | insig. | 47 | 98 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS07760 | | heavy metal response regulator transcription factor | insig. | 44 | 99 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS07760 | | heavy metal response regulator transcription factor | insig. | 44 | 99 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_4210 | | DNA-binding heavy metal response regulator | insig. | 43 | 100 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_00891 | | Transcriptional activator protein CzcR | cofit | 45 | 98 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS03480 | | heavy metal response regulator transcription factor | insig. | 44 | 100 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS03480 | | heavy metal response regulator transcription factor | insig. | 44 | 100 |
| | Pseudomonas simiae WCS417 | PS417_07685 | | transcriptional regulator | insig. | 44 | 99 |
| o | Escherichia fergusonii Becca | EFB2_03523 | | Transcriptional regulatory protein CusR | insig. | 43 | 100 |
| o | Escherichia coli ECOR38 | HEPCGN_00585 | cusR | copper response regulator transcription factor CusR | insig. | 43 | 100 |
| o | Escherichia coli ECRC100 | OKFHMN_07705 | cusR | copper response regulator transcription factor CusR | cofit | 43 | 100 |
| o | Escherichia coli ECRC101 | MCAODC_26920 | cusR | copper response regulator transcription factor CusR | insig. | 43 | 100 |
| o | Escherichia coli ECRC102 | NIAGMN_05760 | cusR | copper response regulator transcription factor CusR | insig. | 43 | 100 |
| o | Escherichia coli ECRC62 | BNILDI_22095 | cusR | copper response regulator transcription factor CusR | insig. | 43 | 100 |
| o | Escherichia coli ECRC98 | JDDGAC_11350 | cusR | copper response regulator transcription factor CusR | insig. | 43 | 100 |
| o | Escherichia coli ECRC99 | KEDOAH_20265 | cusR | copper response regulator transcription factor CusR | no data | 43 | 100 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03138 | | Transcriptional regulatory protein CusR | insig. | 43 | 100 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS03125 | | copper response regulator transcription factor CusR | no data | 43 | 100 |
| o | Escherichia coli BW25113 | b0571 | cusR | DNA-binding response regulator in two-component regulatory system with CusS (NCBI) | sig. | 43 | 100 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS12420 | | transcriptional regulator | insig. | 44 | 98 |
| o | Escherichia coli BL21 | ECD_00532 | | response regulator in two-component regulatory system with CusS | insig. | 43 | 100 |
| o | Escherichia coli ECOR27 | NOLOHH_24085 | cusR | copper response regulator transcription factor CusR | insig. | 43 | 100 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1012 | sphR | two component transcriptional regulator, winged helix family | strong | 42 | 97 |
| | Acinetobacter baumannii LAC-4 | RR41_RS06560 | | heavy metal response regulator transcription factor | insig. | 43 | 97 |
| | Acinetobacter baumannii LAC-4 | RR41_RS02755 | | heavy metal response regulator transcription factor | insig. | 41 | 98 |
| o | Enterobacter sp. TBS_079 | MPMX20_02319 | | Transcriptional regulatory protein CusR | insig. | 43 | 100 |
| | Pseudomonas orientalis W4I3 | QF045_RS10330 | | heavy metal response regulator transcription factor | insig. | 44 | 99 |
| o | Alteromonas macleodii MIT1002 | MIT1002_01421 | | Transcriptional regulatory protein PhoP | insig. | 43 | 97 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS06340 | | response regulator transcription factor | strong | 41 | 97 |
| | Pseudomonas simiae WCS417 | PS417_03365 | | transcriptional regulator | insig. | 44 | 100 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_00640 | | copper response regulator transcription factor PcoR | insig. | 43 | 97 |
| | Azospirillum brasilense Sp245 | AZOBR_RS10800 | | XRE family transcriptional regulator | sig. | 43 | 98 |
| | Sphingobium sp. HT1-2 | GFF5177 | | Two-component transcriptional response regulator, OmpR family | cofit | 43 | 99 |
| | Shewanella loihica PV-4 | Shew_3258 | | two component heavy metal response transcriptional regulator (RefSeq) | strong | 39 | 98 |
| o | Acinetobacter radioresistens SK82 | MPMX26_03114 | | Transcriptional regulatory protein CusR | cofit | 40 | 98 |
| | Rahnella sp. WP5 | EX31_RS18870 | | heavy metal response regulator transcription factor | insig. | 44 | 97 |
| | Pseudomonas putida KT2440 | PP_2713 | | DNA-binding response regulator | sig. | 44 | 98 |
| | Azospirillum sp. SherDot2 | MPMX19_00794 | | Transcriptional activator protein CopR | sig. | 43 | 98 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS15310 | | response regulator transcription factor | strong | 42 | 96 |
| | Variovorax sp. SCN45 | GFF5812 | | DNA-binding heavy metal response regulator | insig. | 42 | 98 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1404 | | two component transcriptional regulator, winged helix family | no data | 45 | 97 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2266 | | Copper-sensing two-component system response regulator CusR | insig. | 44 | 99 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_00710 | | copper/silver response regulator transcription factor SilR | insig. | 43 | 100 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS25955 | | transcriptional regulator | insig. | 46 | 98 |
| | Pseudomonas sp. RS175 | PFR28_01134 | | Transcriptional activator protein CopR | insig. | 45 | 99 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3258 | | DNA-binding heavy metal response regulator | insig. | 44 | 99 |
| | Pectobacterium carotovorum WPP14 | HER17_RS13650 | | heavy metal response regulator transcription factor | insig. | 43 | 100 |
| | Klebsiella pneumoniae MRSN742743 | GJGHJB_05220 | silR | copper/silver response regulator transcription factor SilR | insig. | 43 | 100 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_02215 | | transcriptional regulator | cofit | 45 | 99 |
| | Caulobacter crescentus NA1000 | CCNA_01351 | | two-component response regulator protein | cofit | 43 | 100 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01351 | | two-component response regulator protein | cofit | 43 | 100 |
| | Pseudomonas sp. BP01 | JOY50_RS25150 | cinR | two-component system response regulator CinR | insig. | 44 | 99 |
| | Pseudomonas simiae WCS417 | PS417_18460 | | transcriptional regulator | sig. | 44 | 100 |
| o | Bacteroides ovatus ATCC 8483 | BACOVA_02385 | | response regulator receiver domain protein | insig. | 41 | 98 |
| | Azospirillum brasilense Sp245 | AZOBR_RS29445 | | transcriptional regulator | insig. | 46 | 98 |
| | Pseudomonas protegens RBAN4 | FABNJH_01055 | czcR | Transcriptional activator protein CzcR | insig. | 45 | 100 |
| | Pseudomonas sp. DMC3 | GFF4241 | | Transcriptional activator protein CzcR | cofit | 44 | 100 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS15315 | | transcriptional regulator | insig. | 44 | 99 |
| | Pseudomonas sp. DMC3 | GFF3411 | | Transcriptional activator protein CopR | cofit | 44 | 98 |
| | Pseudomonas putida KT2440 | PP_0029 | | two component heavy metal response regulator | insig. | 42 | 99 |
| | Pseudomonas stutzeri RCH2 | Psest_1598 | | heavy metal response regulator | insig. | 46 | 99 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_28575 | | transcriptional regulator | insig. | 44 | 100 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS01665 | | response regulator transcription factor | insig. | 42 | 97 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4209 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 39 | 99 |
| o | Shewanella sp. ANA-3 | Shewana3_4296 | | DNA-binding transcriptional activator CusR (RefSeq) | insig. | 43 | 100 |
| | Azospirillum sp. SherDot2 | MPMX19_06359 | | Transcriptional activator protein CopR | no data | 44 | 100 |
| | Azospirillum sp. SherDot2 | MPMX19_06441 | | Transcriptional activator protein CopR | no data | 44 | 100 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS20435 | | heavy metal response regulator transcription factor | insig. | 44 | 100 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS20435 | | heavy metal response regulator transcription factor | insig. | 44 | 100 |
| | Variovorax sp. SCN45 | GFF4069 | | DNA-binding heavy metal response regulator | insig. | 44 | 98 |
| | Paraburkholderia graminis OAS925 | ABIE53_005703 | | two-component system copper resistance phosphate regulon response regulator CusR | sig. | 42 | 99 |
| | Marinobacter adhaerens HP15 | HP15_3484 | | DNA-binding response regulator | no data | 39 | 99 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1757 | | response regulator in two-component regulatory system with PhoQ | cofit | 44 | 96 |
| | Acinetobacter radioresistens SK82 | MPMX26_01710 | | Transcriptional activator protein CzcR | no data | 41 | 98 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_00180 | | response regulator receiver domain protein | sig. | 38 | 97 |
| | Pseudomonas segetis P6 | ACVTMO_RS00245 | | heavy metal response regulator transcription factor | insig. | 46 | 98 |
| | Pseudomonas putida KT2440 | PP_2158 | | transcriptional activator protein | no data | 44 | 99 |
| | Pseudomonas orientalis W4I3 | QF045_RS20600 | | heavy metal response regulator transcription factor | insig. | 44 | 100 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS14570 | | DNA-binding response regulator | no data | 43 | 98 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1369 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 42 | 99 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_17925 | | transcriptional regulator | insig. | 42 | 98 |
| | Pseudomonas sp. RS175 | PFR28_02431 | | Regulator of RpoS | insig. | 43 | 98 |
| | Alteromonas macleodii MIT1002 | MIT1002_03097 | | Transcriptional activator protein CopR | insig. | 41 | 97 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1120 | | DNA-binding heavy metal response regulator | insig. | 44 | 98 |
| | Pseudomonas sp. DMC3 | GFF1578 | | Transcriptional regulatory protein CusR | cofit | 42 | 98 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_15165 | | DNA-binding response regulator | insig. | 41 | 98 |
| | Pseudomonas protegens RBAN4 | FABNJH_16165 | | DNA-binding response regulator | insig. | 42 | 100 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS17605 | | response regulator transcription factor | sig. | 42 | 97 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02256 | | Transcriptional activator protein CzcR | insig. | 41 | 100 |
| | Pseudomonas protegens RBAN4 | FABNJH_25495 | ompR | DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain | insig. | 41 | 98 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS31535 | | transcriptional regulator | insig. | 45 | 98 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS24495 | | transcriptional regulator | strong | 44 | 97 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS27985 | | response regulator | insig. | 42 | 97 |
| | Pseudomonas sp. DMC3 | GFF3631 | | Transcriptional activator protein CzcR | cofit | 41 | 100 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3374 | | Heavy metal response regulator | insig. | 41 | 100 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3374 | | Heavy metal response regulator | insig. | 41 | 100 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1663 | | heavy metal response regulator | insig. | 41 | 98 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS06935 | | phosphate regulon transcriptional regulatory protein PhoB | insig. | 41 | 97 |
| | Rhodospirillum rubrum S1H | Rru_A2913 | | Two component Transcriptional regulator, Winged helix family (NCBI) | insig. | 43 | 98 |
| o | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13516_RS00320 | qseB | quorum sensing response regulator transcription factor QseB | cofit | 41 | 98 |
| | Pseudomonas stutzeri RCH2 | Psest_1185 | | heavy metal response regulator | insig. | 45 | 98 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS30960 | | transcriptional regulator | strong | 44 | 99 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03921 | | Transcriptional activator protein CzcR | cofit | 43 | 100 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1453 | rpaB | two component transcriptional regulator, winged helix family | no data | 43 | 98 |
| o | Pantoea sp. MT58 | IAI47_00340 | | response regulator | insig. | 41 | 98 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS02475 | | response regulator | cofit | 44 | 98 |
| | Pseudomonas aeruginosa MRSN321 | PFGADD_05005 | pmrA | two-component system response regulator PrmA | insig. | 43 | 100 |
| | Pseudomonas aeruginosa PUPa3 | NPBIFN_05082 | pmrA | two-component system response regulator PrmA | sig. | 43 | 100 |
| | Xanthobacter sp. DMC5 | GFF3127 | | Transcriptional regulatory protein CusR | no data | 42 | 98 |
| | Lysobacter sp. OAE881 | ABIE51_RS04165 | | response regulator transcription factor | insig. | 42 | 99 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_25490 | | transcriptional regulator | insig. | 42 | 98 |
| | Rhodopseudomonas palustris CGA009 | TX73_009945 | | response regulator transcription factor | insig. | 41 | 99 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_08235 | | DNA-binding response regulator | cofit | 39 | 98 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS03230 | | heavy metal response regulator transcription factor | insig. | 43 | 98 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_29710 | | two-component system response regulator PrmA | sig. | 43 | 100 |
| | Pseudomonas stutzeri RCH2 | Psest_0581 | | heavy metal response regulator | sig. | 43 | 100 |
| | Xanthobacter sp. DMC5 | GFF2342 | | Phosphate regulon transcriptional regulatory protein PhoB | no data | 45 | 98 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS00075 | | transcriptional regulator | insig. | 44 | 98 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS11370 | | response regulator transcription factor | no data | 43 | 98 |
| | Agrobacterium fabrum C58 | Atu0978 | | two component response regulator | strong | 42 | 99 |
| | Shewanella loihica PV-4 | Shew_3637 | ompR | osmolarity response regulator (RefSeq) | strong | 42 | 97 |
| | Ralstonia solanacearum GMI1000 | RS_RS24590 | | DNA-binding response regulator | insig. | 41 | 100 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS05370 | | response regulator transcription factor | insig. | 41 | 97 |
| | Pseudomonas orientalis W4I3 | QF045_RS14560 | | response regulator transcription factor | cofit | 43 | 98 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_23125 | | transcriptional regulator | sig. | 43 | 98 |
| | Bosea sp. OAE506 | ABIE41_RS21440 | | response regulator transcription factor | insig. | 42 | 99 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS22890 | | response regulator transcription factor | insig. | 40 | 100 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS08970 | | phosphate regulon transcriptional regulator PhoB | no data | 43 | 97 |
| | Dickeya dadantii 3937 | DDA3937_RS01140 | | heavy metal response regulator transcription factor | insig. | 42 | 97 |
| | Sphingobium sp. HT1-2 | GFF4076 | | Two-component transcriptional response regulator, LuxR family | strong | 42 | 99 |
| | Pseudomonas aeruginosa MRSN321 | PFGADD_03790 | | DNA-binding response regulator | insig. | 42 | 98 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_06830 | | DNA-binding response regulator | sig. | 42 | 98 |
| | Pseudomonas aeruginosa PUPa3 | NPBIFN_03831 | | DNA-binding response regulator | insig. | 42 | 98 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1127 | | Heavy metal response regulator | insig. | 39 | 98 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1127 | | Heavy metal response regulator | insig. | 39 | 98 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0990 | | two-component system response regulator (NCBI ptt file) | sig. | 37 | 97 |
| | Fusobacterium nucleatum SB010 | HUW76_03950 | | response regulator transcription factor | strong | 36 | 98 |
| | Pseudomonas segetis P6 | ACVTMO_RS00395 | | heavy metal response regulator transcription factor | insig. | 43 | 99 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1663 | | DNA-binding heavy metal response regulator | insig. | 40 | 98 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS01000 | | response regulator transcription factor | insig. | 37 | 100 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4389 | | Two-component system response regulator OmpR | sig. | 45 | 97 |
| | Sinorhizobium meliloti 1021 | SMc02140 | | phosphate regulon transcriptional regulatory protein | strong | 44 | 97 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS21985 | | transcriptional regulator | insig. | 43 | 98 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS09165 | | transcriptional regulator | insig. | 42 | 98 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_4800 | | Heavy metal response regulator | insig. | 42 | 98 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_4800 | | Heavy metal response regulator | insig. | 42 | 98 |
| | Pseudomonas sp. BP01 | JOY50_RS03360 | | response regulator | insig. | 41 | 98 |
| | Pseudomonas sp. RS175 | PFR28_03578 | | Transcriptional activator protein CzcR | sig. | 40 | 98 |
| | Shewanella loihica PV-4 | Shew_0097 | | two component transcriptional regulator (RefSeq) | strong | 39 | 99 |
| | Pseudomonas simiae WCS417 | PS417_11825 | | transcriptional regulator | sig. | 43 | 98 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS12570 | | response regulator transcription factor | insig. | 43 | 98 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS12570 | | response regulator transcription factor | insig. | 43 | 98 |
| | Caulobacter crescentus NA1000 | CCNA_00296 | | phosphate regulon response regulator PhoB | strong | 42 | 97 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00296 | | phosphate regulon response regulator PhoB | cofit | 42 | 97 |
| | Pseudomonas sp. SVBP6 | COO64_RS16580 | | heavy metal response regulator transcription factor | insig. | 43 | 98 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_26815 | | transcriptional regulator | insig. | 42 | 98 |
| | Pseudomonas sp. S08-1 | OH686_20005 | | Tricarboxylate transport transcriptional regulator TctD | strong | 45 | 98 |
| | Pseudomonas sp. SVBP6 | COO64_RS16490 | | response regulator | strong | 44 | 98 |
| | Azospirillum brasilense Sp245 | AZOBR_RS18790 | | transcriptional regulator | insig. | 43 | 100 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_504 | | DNA-binding response regulator | sig. | 42 | 98 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01140 | | Transcriptional activator protein CzcR | insig. | 41 | 98 |
| | Agrobacterium fabrum C58 | Atu0629 | | two component response regulator | insig. | 41 | 98 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_17205 | | transcriptional regulator | insig. | 40 | 98 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5366 | | DNA-binding heavy metal response regulator | insig. | 40 | 98 |
| | Enterobacter sp. TBS_079 | MPMX20_01501 | | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP | insig. | 39 | 98 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_0095 | rpaA | two component transcriptional regulator, winged helix family | strong | 42 | 97 |
| | Pseudomonas sp. DMC3 | GFF4407 | | Transcriptional activator protein CzcR | insig. | 40 | 98 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS04765 | | heavy metal response regulator transcription factor | insig. | 40 | 100 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS04765 | | heavy metal response regulator transcription factor | insig. | 40 | 100 |
| | Azospirillum sp. SherDot2 | MPMX19_03749 | | KDP operon transcriptional regulatory protein KdpE | insig. | 46 | 98 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3316 | | Tricarboxylate transport transcriptional regulator TctD | sig. | 44 | 98 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS19035 | | response regulator | insig. | 44 | 97 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4524 | | Tricarboxylate transport transcriptional regulator TctD | strong | 44 | 98 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02648 | | Transcriptional regulatory protein CusR | insig. | 42 | 98 |
| | Variovorax sp. SCN45 | GFF1238 | | Two-component transcriptional response regulator, OmpR family | insig. | 42 | 99 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2490 | | sensor histidine kinase | insig. | 42 | 97 |
| | Rhizobium sp. OAE497 | ABIE40_RS05700 | | response regulator transcription factor | insig. | 42 | 99 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4267 | | DNA-binding response regulator | no data | 42 | 98 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3273 | | Putative two-component system response regulator YedW | insig. | 41 | 98 |
| | Serratia liquefaciens MT49 | IAI46_12390 | | heavy metal response regulator transcription factor | insig. | 40 | 98 |
| | Dickeya dadantii 3937 | DDA3937_RS03385 | | heavy metal response regulator transcription factor | insig. | 40 | 98 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0682 | | two-component system response regulator (NCBI ptt file) | sig. | 40 | 98 |
| o | Methylophilus sp. DMC18 | GFF2713 | | Transcriptional regulatory protein OmpR | no data | 41 | 97 |
| | Azospirillum brasilense Sp245 | AZOBR_RS01105 | | PhoB family transcriptional regulator | insig. | 41 | 97 |
| | Pseudomonas orientalis W4I3 | QF045_RS07685 | | heavy metal response regulator transcription factor | cofit | 40 | 98 |