| Orth |  Species |  Gene |  Name |  Description |  Fitness |  %Id |  Cov | 
|   |  Erwinia amylovora T8 |  OLJFJH_09295 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  100 |  100 | 
| o |  Pantoea agglomerans CFBP13505 P0401 |  PagCFBP13505_RS16820 |   |  6-carboxytetrahydropterin synthase QueD |  cofit |  91 |  100 | 
| o |  Pantoea sp. MT58 |  IAI47_04145 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  90 |  100 | 
| o |  Erwinia tracheiphila HP pepo 2.2 |  IJEDHG_17415 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  88 |  100 | 
| o |  Erwinia tracheiphila SCR3 |  LU632_RS06395 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  88 |  100 | 
| o |  Klebsiella pneumoniae MKP103 |  KDGMDA_03305 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  87 |  100 | 
| o |  Enterobacter asburiae PDN3 |  EX28DRAFT_2854 |   |  queuosine biosynthesis protein QueD |  insig. |  87 |  100 | 
| o |  Klebsiella michiganensis M5al |  BWI76_RS22775 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  87 |  100 | 
| o |  Enterobacter sp. TBS_079 |  MPMX20_03644 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  sig. |  86 |  100 | 
| o |  Escherichia coli ECOR38 |  HEPCGN_19100 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  85 |  100 | 
| o |  Dickeya dianthicola 67-19 |  HGI48_RS17030 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  85 |  100 | 
| o |  Dickeya dadantii 3937 |  DDA3937_RS16965 |   |  6-carboxytetrahydropterin synthase QueD |  sig. |  86 |  100 | 
| o |  Serratia liquefaciens MT49 |  IAI46_03680 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  84 |  100 | 
| o |  Pectobacterium carotovorum WPP14 |  HER17_RS04205 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  86 |  100 | 
| o |  Rahnella sp. WP5 |  EX31_RS07915 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  86 |  100 | 
| o |  Escherichia fergusonii Becca |  EFB2_01152 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  insig. |  83 |  100 | 
| o |  Escherichia coli BL21 |  ECD_02610 |   |  6-pyruvoyl tetrahydrobiopterin synthase (PTPS) |  sig. |  83 |  100 | 
| o |  Escherichia coli ECOR27 |  NOLOHH_12180 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  83 |  100 | 
| o |  Escherichia coli ECRC100 |  OKFHMN_20365 |  queD |  6-carboxytetrahydropterin synthase QueD |  cofit |  83 |  100 | 
| o |  Escherichia coli ECRC101 |  MCAODC_10890 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  83 |  100 | 
| o |  Escherichia coli ECRC102 |  NIAGMN_18135 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  83 |  100 | 
| o |  Escherichia coli ECRC62 |  BNILDI_10730 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  83 |  100 | 
| o |  Escherichia coli ECRC98 |  JDDGAC_24030 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  83 |  100 | 
| o |  Escherichia coli ECRC99 |  KEDOAH_07760 |  queD |  6-carboxytetrahydropterin synthase QueD |  no data |  83 |  100 | 
| o |  Escherichia coli HS(pFamp)R (ATCC 700891) |  OHPLBJKB_00968 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  insig. |  83 |  100 | 
| o |  Escherichia coli Nissle 1917 |  ECOLIN_RS15415 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  83 |  100 | 
| o |  Escherichia coli BW25113 |  b2765 |  ygcM |  6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (NCBI) |  sig. |  83 |  100 | 
| o |  Dickeya dianthicola ME23 |  DZA65_RS18105 |   |  6-carboxytetrahydropterin synthase QueD |  sig. |  83 |  100 | 
| o |  Vibrio cholerae E7946 ATCC 55056 |  CSW01_06560 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  82 |  100 | 
| o |  Pseudomonas segetis P6 |  MPMX49_02208 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  insig. |  76 |  97 | 
| o |  Pseudomonas fluorescens SBW25 |  PFLU_RS10415 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  71 |  97 | 
| o |  Pseudomonas fluorescens SBW25-INTG |  PFLU_RS10415 |   |  6-carboxytetrahydropterin synthase QueD |  sig. |  71 |  97 | 
| o |  Pseudomonas lactucae CFBP13502 |  GEMAOFIL_02161 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  cofit |  71 |  97 | 
| o |  Pseudomonas simiae WCS417 |  PS417_09830 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  sig. |  71 |  97 | 
| o |  Pseudomonas fluorescens FW300-N1B4 |  Pf1N1B4_110 |   |  Queuosine biosynthesis QueD, PTPS-I |  insig. |  71 |  97 | 
| o |  Pseudomonas sp. DMC3 |  GFF1361 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  cofit |  72 |  97 | 
| o |  Pseudomonas fluorescens GW456-L13 |  PfGW456L13_2447 |   |  6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I |  sig. |  71 |  97 | 
| o |  Pseudomonas fluorescens FW300-N2C3 |  AO356_21260 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  insig. |  70 |  97 | 
| o |  Pseudomonas sp. RS175 |  PFR28_02851 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  insig. |  70 |  97 | 
| o |  Pseudomonas fluorescens FW300-N2E2 |  Pf6N2E2_37 |   |  6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I |  strong |  70 |  97 | 
| o |  Pseudomonas fluorescens FW300-N2E3 |  AO353_19760 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  insig. |  70 |  97 | 
| o |  Pseudomonas aeruginosa PA14 |  IKLFDK_13390 |   |  6-carboxytetrahydropterin synthase QueD |  no data |  74 |  97 | 
| o |  Pseudomonas syringae pv. syringae B728a |  Psyr_3215 |   |  6-pyruvoyl tetrahydropterin synthase and hypothetical protein |  no data |  72 |  97 | 
| o |  Pseudomonas syringae pv. syringae B728a ΔmexB |  Psyr_3215 |   |  6-pyruvoyl tetrahydropterin synthase and hypothetical protein |  no data |  72 |  97 | 
| o |  Pseudomonas sp. SVBP6 |  COO64_RS17240 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  71 |  97 | 
| o |  Pseudomonas putida KT2440 |  PP_2341 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  sig. |  70 |  97 | 
| o |  Lysobacter sp. OAE881 |  ABIE51_RS17950 |   |  6-carboxytetrahydropterin synthase QueD |  sig. |  68 |  97 | 
| o |  Pseudomonas sp. BP01 |  JOY50_RS10905 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  69 |  97 | 
| o |  Xanthomonas campestris pv. campestris strain 8004 |  Xcc-8004.4528.1 |   |  hypothetical protein |  insig. |  70 |  97 | 
| o |  Pseudomonas stutzeri RCH2 |  Psest_2010 |   |  queuosine biosynthesis protein QueD |  no data |  70 |  97 | 
| o |  Rhodanobacter denitrificans MT42 |  LRK55_RS09085 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  67 |  97 | 
| o |  Pseudomonas sp. S08-1 |  OH686_00030 |   |  queuosine biosynthesis protein QueD |  insig. |  73 |  97 | 
|   |  Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 |  GFF4822 |   |  Queuosine biosynthesis QueD, PTPS-I |  strong |  85 |  71 | 
| o |  Rhodanobacter sp000427505 FW510-R12 |  LRK53_RS02150 |   |  6-carboxytetrahydropterin synthase QueD |  sig. |  64 |  92 | 
| o |  Rhodanobacter sp. FW510-T8 |  OKGIIK_15925 |  queD |  6-carboxytetrahydropterin synthase QueD |  insig. |  64 |  92 | 
|   |  Rhodanobacter denitrificans MT42 |  LRK55_RS09315 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  63 |  92 | 
| o |  Rhodanobacter denitrificans FW104-10B01 |  LRK54_RS09655 |   |  6-carboxytetrahydropterin synthase QueD |  strong |  63 |  92 | 
| o |  Dyella japonica UNC79MFTsu3.2 |  ABZR86_RS13650 |   |  6-carboxytetrahydropterin synthase QueD |  cofit |  64 |  92 | 
| o |  Desulfovibrio vulgaris Miyazaki F |  DvMF_1123 |   |  queuosine biosynthesis protein QueD (RefSeq) |  no data |  58 |  97 | 
| o |  Desulfovibrio vulgaris Hildenborough JW710 |  DVU2657 |   |  6-pyruvoyl tetrahydrobiopterin synthase, putative (TIGR) |  insig. |  57 |  97 | 
|   |  Xanthobacter sp. DMC5 |  GFF3475 |   |  hypothetical protein |  insig. |  58 |  86 | 
| o |  Rhodopseudomonas palustris CGA009 |  TX73_008525 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  52 |  95 | 
| o |  Synechocystis sp000284455 PCC 6803 |  SGL_RS15290 |   |  6-carboxytetrahydropterin synthase QueD |  strong |  50 |  95 | 
| o |  Agrobacterium fabrum C58 |  Atu3345 |   |  6-pyruvoyl tetrahydrobiopterin synthase |  insig. |  40 |  94 | 
| o |  Sinorhizobium meliloti 1021 |  SM_b20939 |   |  6-pyruvoyl-tetrahydropterin synthase |  insig. |  37 |  99 | 
| o |  Caulobacter crescentus NA1000 |  CCNA_03260 |   |  queuosine biosynthesis protein QueD |  strong |  41 |  89 | 
| o |  Caulobacter crescentus NA1000 Δfur |  CCNA_03260 |   |  queuosine biosynthesis protein QueD |  cofit |  41 |  89 | 
| o |  Brevundimonas sp. GW460-12-10-14-LB2 |  A4249_RS08690 |   |  6-carboxytetrahydropterin synthase |  no data |  39 |  94 | 
| o |  Phaeobacter inhibens DSM 17395 |  PGA1_c05610 |   |  putative queuosine biosynthesis protein QueD |  insig. |  37 |  96 | 
|   |  Desulfovibrio vulgaris Miyazaki F |  DvMF_0129 |   |  6-pyruvoyl tetrahydropterin synthase and hypothetical protein (RefSeq) |  no data |  38 |  91 | 
| o |  Acidovorax sp. GW101-3H11 |  Ac3H11_3826 |   |  6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I |  insig. |  34 |  97 | 
|   |  Hydrogenophaga sp. GW460-11-11-14-LB1 |  GFF4632 |   |  6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I |  no data |  35 |  78 | 
| o |  Variovorax sp. SCN45 |  GFF2576 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase (EC 4.1.2.50) |  cofit |  35 |  91 | 
| o |  Variovorax sp. OAS795 |  ABID97_RS07420 |   |  6-carboxytetrahydropterin synthase |  insig. |  35 |  91 | 
|   |  Desulfovibrio vulgaris Hildenborough JW710 |  DVU1352 |   |  6-pyruvoyl tetrahydrobiopterin synthase, putative (TIGR) |  no data |  36 |  91 | 
| o |  Phocaeicola dorei CL03T12C01 |  ABI39_RS10595 |   |  6-carboxytetrahydropterin synthase QueD |  sig. |  34 |  96 | 
| o |  Phocaeicola vulgatus CL09T03C04 |  HMPREF1058_RS14875 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  33 |  96 | 
| o |  Methylophilus sp. DMC18 |  GFF1366 |   |  hypothetical protein |  insig. |  33 |  90 | 
| o |  Bacteroides stercoris CC31F |  HMPREF1181_RS13890 |   |  6-carboxytetrahydropterin synthase QueD |  cofit |  33 |  96 | 
|   |  Synechococcus elongatus PCC 7942 |  Synpcc7942_1184 |   |  6-pyruvoyl-tetrahydropterin synthase-like protein |  strong |  39 |  65 | 
| o |  Parabacteroides merdae CL09T00C40 |  HMPREF1078_RS00755 |   |  6-carboxytetrahydropterin synthase QueD |  no data |  34 |  96 | 
|   |  Bacteroides thetaiotaomicron VPI-5482 |  BT4453 |   |  6-pyruvoyl-tetrahydropterin synthase (NCBI ptt file) |  strong |  33 |  90 | 
|   |  Bacteroides stercoris CC31F |  HMPREF1181_RS07300 |   |  6-carboxytetrahydropterin synthase QueD |  insig. |  32 |  90 | 
|   |  Synechococcus elongatus PCC 7942 |  Synpcc7942_1953 |   |  6-pyruvoyl tetrahydrobiopterin synthase |  strong |  35 |  96 | 
|   |  Cellulophaga baltica 18 |  M666_RS09275 |   |  6-carboxytetrahydropterin synthase |  insig. |  34 |  59 | 
|   |  Pontibacter actiniarum KMM 6156, DSM 19842 |  CA264_20555 |   |  6-pyruvoyl tetrahydrobiopterin synthase |  sig. |  30 |  83 | 
|   |  Herbaspirillum seropedicae SmR1 |  HSERO_RS11040 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  insig. |  31 |  71 | 
|   |  Methylophilus sp. DMC18 |  GFF1325 |   |  hypothetical protein |  sig. |  33 |  55 | 
|   |  Ralstonia sp. UNC404CL21Col |  ABZR87_RS12150 |   |  6-carboxytetrahydropterin synthase QueD |  sig. |  29 |  82 | 
|   |  Methanococcus maripaludis JJ |  MMJJ_RS07920 |   |  6-carboxytetrahydropterin synthase QueD |  cofit |  36 |  58 | 
|   |  Methanococcus maripaludis S2 |  MMP_RS06430 |   |  6-carboxytetrahydropterin synthase QueD |  sig. |  36 |  58 | 
|   |  Paraburkholderia bryophila 376MFSha3.1 |  H281DRAFT_02230 |   |   6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase |  strong |  33 |  59 | 
|   |  Acinetobacter baumannii LAC-4 |  RR41_RS12105 |   |  6-carboxytetrahydropterin synthase |  strong |  29 |  84 | 
|   |  Burkholderia phytofirmans PsJN |  BPHYT_RS01510 |   |  6-carboxy-5,6,7,8-tetrahydropterin synthase |  strong |  33 |  59 | 
|   |  Paraburkholderia graminis OAS925 |  ABIE53_000398 |   |  6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase |  strong |  33 |  59 | 
|   |  Dechlorosoma suillum PS |  Dsui_2137 |   |  queuosine biosynthesis protein QueD |  insig. |  32 |  58 | 
|   |  Acinetobacter radioresistens SK82 |  MPMX26_01230 |   |  hypothetical protein |  strong |  29 |  84 | 
|   |  Synechococcus elongatus PCC 7942 |  Synpcc7942_1184 |   |  6-pyruvoyl-tetrahydropterin synthase-like protein |  strong |  34 |  71 | 
|   |  Ralstonia solanacearum IBSBF1503 |  RALBFv3_RS00620 |   |  6-carboxytetrahydropterin synthase |  no data |  34 |  61 | 
|   |  Ralstonia solanacearum UW163 |  UW163_RS13950 |   |  6-carboxytetrahydropterin synthase |  no data |  34 |  61 |