| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2271 | | His Kinase A (phosphoacceptor) domain./Response regulator receiver domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | strong | 100 | 100 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS14555 | | response regulator | strong | 50 | 41 |
| | Cellulophaga baltica 18 | M666_RS19930 | | PAS domain S-box protein | insig. | 35 | 64 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2267 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | strong | 51 | 39 |
| o | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4858 | | Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY | sig. | 28 | 98 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02959 | | Sensor histidine kinase RcsC | insig. | 25 | 98 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS14725 | | hybrid sensor histidine kinase/response regulator | cofit | 26 | 98 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS14725 | | hybrid sensor histidine kinase/response regulator | strong | 26 | 98 |
| | Dechlorosoma suillum PS | Dsui_1890 | | diguanylate cyclase (GGDEF) domain-containing protein | insig. | 46 | 37 |
| | Dechlorosoma suillum PS | Dsui_2046 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 34 | 45 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_2448 | | Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal | sig. | 26 | 98 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2448 | | Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal | insig. | 26 | 98 |
| o | Pseudomonas fluorescens FW300-N2E3 | AO353_23925 | | histidine kinase | sig. | 26 | 98 |
| o | Pseudomonas simiae WCS417 | PS417_13890 | | histidine kinase | no data | 25 | 98 |
| o | Pseudomonas fluorescens GW456-L13 | PfGW456L13_3051 | | Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY | insig. | 25 | 98 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS05725 | | PAS domain S-box protein | insig. | 31 | 65 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3165 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 40 | 36 |
| | Pseudomonas orientalis W4I3 | QF045_RS16055 | | hybrid sensor histidine kinase/response regulator | cofit | 25 | 98 |
| | Pseudomonas sp. S08-1 | OH686_08910 | | Phytochrome-like protein / Cph2 | cofit | 45 | 32 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_05530 | | two-component system response regulator | cofit | 38 | 37 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS11055 | | DUF3365 domain-containing protein | insig. | 29 | 80 |
| | Xanthobacter sp. DMC5 | GFF1741 | | Adaptive-response sensory-kinase SasA | insig. | 29 | 65 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS23945 | | DUF3365 domain-containing protein | cofit | 33 | 64 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_17130 | | histidine kinase | insig. | 29 | 75 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS18845 | | PAS domain S-box protein | cofit | 27 | 90 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_14640 | | two-component system response regulator | insig. | 37 | 34 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS33010 | | response regulator | insig. | 37 | 34 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS02585 | | response regulator | insig. | 37 | 34 |
| | Pseudomonas segetis P6 | ACVTMO_RS10700 | | response regulator | insig. | 35 | 34 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3168 | | Response regulator | insig. | 37 | 41 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4657 | | Signal transduction histidine kinase | cofit | 32 | 65 |
| | Pseudomonas sp. S08-1 | OH686_08945 | | hypothetical protein | cofit | 34 | 42 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1489 | | Sensory box histidine kinase | insig. | 28 | 70 |
| o | Cupriavidus basilensis FW507-4G11 | RR42_RS17425 | | chemotaxis protein CheY | cofit | 22 | 99 |
| | Pseudomonas sp. RS175 | PFR28_03482 | | Sensor histidine kinase RcsC | cofit | 36 | 42 |
| | Rhodospirillum rubrum S1H | Rru_A2606 | | Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI) | insig. | 30 | 64 |
| o | Sphingobium sp. HT1-2 | GFF4510 | | hypothetical protein | cofit | 28 | 99 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5467 | | Response regulator | sig. | 36 | 42 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_27635 | | histidine kinase | strong | 24 | 98 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1238 | | His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | insig. | 27 | 100 |
| | Pseudomonas sp. DMC3 | GFF2887 | | Sensor histidine kinase RcsC | cofit | 26 | 98 |
| | Alteromonas macleodii MIT1002 | MIT1002_03637 | | Hydrogenase transcriptional regulatory protein hupR1 | insig. | 37 | 38 |
| | Azospirillum sp. SherDot2 | MPMX19_05290 | | Hydrogenase transcriptional regulatory protein hupR1 | insig. | 38 | 35 |
| | Dechlorosoma suillum PS | Dsui_1886 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 37 | 43 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_17715 | | chemotaxis protein CheY | insig. | 36 | 41 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS23670 | | two-component sensor histidine kinase | insig. | 30 | 65 |
| | Pseudomonas simiae WCS417 | PS417_05440 | | chemotaxis protein CheY | insig. | 30 | 43 |
| | Sphingobium sp. HT1-2 | GFF4433 | | hypothetical protein | cofit | 28 | 84 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04086 | | response regulator receiver domain protein | insig. | 27 | 99 |
| | Rhizobium sp. OAE497 | ABIE40_RS02800 | | response regulator | insig. | 23 | 99 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1089 | | PAS domain S-box | insig. | 29 | 68 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2210 | | Hydrogenase transcriptional regulatory protein HoxA | insig. | 34 | 37 |
| o | Paraburkholderia graminis OAS925 | ABIE53_002412 | | two-component system response regulator PhcR | strong | 22 | 100 |
| | Pseudomonas sp. S08-1 | OH686_08920 | | Phytochrome, two-component sensor histidine kinase / cyanobacterial phytochrome 1 | cofit | 30 | 65 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS08760 | | histidine kinase | strong | 27 | 84 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS21620 | | hybrid sensor histidine kinase/response regulator | strong | 27 | 98 |
| | Pseudomonas stutzeri RCH2 | Psest_4070 | | PAS domain S-box | sig. | 29 | 65 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1131 | | response regulator receiver sensor signal transduction histidine kinase (RefSeq) | cofit | 25 | 98 |
| | Dechlorosoma suillum PS | Dsui_1154 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | insig. | 36 | 34 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2768.1 | | hypothetical protein | strong | 39 | 32 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS16850 | | HD domain-containing phosphohydrolase | insig. | 33 | 44 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS24005 | | PAS domain-containing sensor histidine kinase | insig. | 30 | 64 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS10160 | | two-component sensor histidine kinase | cofit | 28 | 65 |
| o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_05136 | | response regulator receiver sensor signal transduction histidine kinase (EC 2.7.13.3) | insig. | 22 | 100 |
| | Shewanella sp. ANA-3 | Shewana3_0542 | | multi-sensor signal transduction histidine kinase (RefSeq) | insig. | 29 | 69 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01276 | | Regulator of RpoS | cofit | 31 | 43 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02781 | | Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains | insig. | 31 | 44 |
| | Pseudomonas orientalis W4I3 | QF045_RS08375 | | response regulator | insig. | 30 | 43 |
| | Rhodopseudomonas palustris CGA009 | TX73_005040 | | sigma-54 dependent transcriptional regulator | insig. | 34 | 36 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS11550 | | sigma-54-dependent Fis family transcriptional regulator | insig. | 32 | 38 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS05525 | | response regulator | insig. | 32 | 43 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS05525 | | response regulator | insig. | 32 | 43 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS18355 | | PAS domain S-box protein | cofit | 30 | 63 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS03395 | | ATP-binding protein | strong | 29 | 73 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS01375 | | two-component system hybrid sensor histidine kinase/response regulator PhcR | strong | 25 | 98 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09010 | | PAS domain-containing sensor histidine kinase | insig. | 28 | 64 |
| | Paraburkholderia graminis OAS925 | ABIE53_006006 | | adenylate cyclase | sig. | 31 | 45 |
| | Dechlorosoma suillum PS | Dsui_2779 | | PAS domain S-box | no data | 29 | 65 |
| | Azospirillum brasilense Sp245 | AZOBR_RS30860 | | sensor histidine kinase | strong | 26 | 73 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS21625 | | histidine kinase | insig. | 34 | 64 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1357 | | multi-sensor signal transduction histidine kinase | insig. | 30 | 64 |
| | Lysobacter sp. OAE881 | ABIE51_RS14685 | | ATP-binding protein | insig. | 28 | 66 |
| | Pseudomonas sp. RS175 | PFR28_01722 | | Sensor histidine kinase RcsC | strong | 25 | 98 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_17855 | | autoinducer 2 sensor kinase/phosphatase LuxQ | cofit | 32 | 76 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS14030 | | ATP-binding protein | cofit | 28 | 73 |
| | Agrobacterium fabrum C58 | Atu1990 | | bacteriophytochrome protein | insig. | 25 | 81 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_16190 | | chemotaxis protein CheY | insig. | 41 | 30 |
| | Lysobacter sp. OAE881 | ABIE51_RS16595 | | EAL domain-containing protein | cofit | 39 | 32 |
| | Xanthobacter sp. DMC5 | GFF4433 | | Hydrogenase transcriptional regulatory protein hupR1 | insig. | 35 | 37 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_04080 | | PAS domain-containing sensor histidine kinase | insig. | 31 | 64 |
| | Rhodopseudomonas palustris CGA009 | TX73_012590 | | CHASE3 domain-containing protein | cofit | 29 | 64 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1058 | | two-component system sensor histidine kinase (NCBI ptt file) | strong | 26 | 99 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_18255 | | hypothetical protein | insig. | 29 | 64 |
| | Agrobacterium fabrum C58 | Atu1986 | | two component sensor kinase | insig. | 27 | 65 |
| | Bosea sp. OAE506 | ABIE41_RS02705 | | ATP-binding protein | no data | 31 | 65 |
| | Pseudomonas sp. SVBP6 | COO64_RS20885 | | HD domain-containing phosphohydrolase | insig. | 31 | 43 |
| | Fusobacterium nucleatum SB010 | HUW76_02045 | | response regulator | strong | 30 | 60 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0064 | | histidine kinase (RefSeq) | sig. | 23 | 99 |
| | Pseudomonas stutzeri RCH2 | Psest_4345 | | Bacteriophytochrome (light-regulated signal transduction histidine kinase) | strong | 26 | 73 |
| | Dechlorosoma suillum PS | Dsui_3334 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 37 | 37 |