Conservation of cofitness between PP_5104 and PP_4922 in Pseudomonas putida KT2440

89 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_5104 thiazole synthase 1.0 PP_4922 Phosphomethylpyrimidine synthase 0.92 1
Pseudomonas fluorescens FW300-N2E2 0.91 Pf6N2E2_4590 Thiazole biosynthesis protein ThiG 0.92 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.77 1
Pseudomonas fluorescens FW300-N2C3 0.91 AO356_13375 thiazole synthase 0.92 AO356_08810 thiamine biosynthesis protein ThiC 0.42 2
Pseudomonas fluorescens FW300-N2E3 0.91 AO353_08215 thiazole synthase 0.92 AO353_13010 thiamine biosynthesis protein ThiC 0.64 1
Pseudomonas sp. RS175 0.91 PFR28_04252 Thiazole synthase 0.92 PFR28_05091 Phosphomethylpyrimidine synthase 0.96 1
Pseudomonas syringae pv. syringae B728a ΔmexB 0.90 Psyr_4740 thiazole-phosphate synthase 0.92 Psyr_0544 hydroxymethylpyrimidine synthase 0.42 77
Pseudomonas syringae pv. syringae B728a 0.90 Psyr_4740 thiazole-phosphate synthase 0.92 Psyr_0544 hydroxymethylpyrimidine synthase low > 86
Pseudomonas fluorescens FW300-N1B4 0.89 Pf1N1B4_2331 Thiazole biosynthesis protein ThiG 0.91 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.55 1
Pseudomonas fluorescens SBW25 0.89 PFLU_RS28420 thiazole synthase 0.92 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.89 2
Pseudomonas fluorescens GW456-L13 0.89 PfGW456L13_1000 Thiazole biosynthesis protein ThiG 0.92 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.90 1
Pseudomonas fluorescens SBW25-INTG 0.89 PFLU_RS28420 thiazole synthase 0.92 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.90 3
Pseudomonas simiae WCS417 0.89 PS417_26775 thiazole synthase 0.91 PS417_02355 thiamine biosynthesis protein ThiC 0.63 6
Pseudomonas sp. S08-1 0.87 OH686_14285 Thiazole synthase 0.91 OH686_15885 phosphomethylpyrimidine synthase 0.77 8
Pseudomonas stutzeri RCH2 0.85 Psest_0267 Uncharacterized enzyme of thiazole biosynthesis 0.90 Psest_0477 thiamine biosynthesis protein ThiC 0.92 1
Lysobacter sp. OAE881 0.69 ABIE51_RS16545 thiazole synthase 0.75 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC — —
Marinobacter adhaerens HP15 0.68 HP15_3274 thiazole synthase 0.83 HP15_453 thiamine biosynthesis protein thiC — —
Dyella japonica UNC79MFTsu3.2 0.68 ABZR86_RS11645 thiazole synthase 0.77 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC — —
Dechlorosoma suillum PS 0.66 Dsui_1014 putative enzyme of thiazole biosynthesis 0.77 Dsui_0422 thiamine biosynthesis protein ThiC — —
Xanthomonas campestris pv. campestris strain 8004 0.66 Xcc-8004.1284.1 Thiazole biosynthesis protein ThiG 0.74 Xcc-8004.1066.1 hypothetical protein 0.76 4
Rhodanobacter sp. FW510-T8 0.65 OKGIIK_11895 thiS thiazole synthase 0.76 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC low > 52
Acinetobacter radioresistens SK82 0.65 MPMX26_01107 Thiazole synthase 0.77 MPMX26_00180 Phosphomethylpyrimidine synthase low > 36
Castellaniella sp019104865 MT123 0.64 ABCV34_RS14510 thiazole synthase 0.75 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC — —
Herbaspirillum seropedicae SmR1 0.64 HSERO_RS02130 thiazole synthase 0.78 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.90 1
Caulobacter crescentus NA1000 Δfur 0.56 CCNA_01957 thiazole biosynthesis protein ThiG 0.66 CCNA_02109 thiamine biosynthesis protein thiC — —
Caulobacter crescentus NA1000 0.56 CCNA_01957 thiazole biosynthesis protein ThiG 0.66 CCNA_02109 thiamine biosynthesis protein thiC — —
Brevundimonas sp. GW460-12-10-14-LB2 0.52 A4249_RS07975 thiazole synthase 0.63 A4249_RS15715 phosphomethylpyrimidine synthase ThiC — —
Azospirillum sp. SherDot2 0.43 MPMX19_00262 Thiazole synthase 0.64 MPMX19_00336 Phosphomethylpyrimidine synthase low > 112
Mycobacterium tuberculosis H37Rv 0.41 Rv0417 Probable thiamin biosynthesis protein ThiG (thiazole biosynthesis protein) 0.53 Rv0423c Probable thiamine biosynthesis protein ThiC — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.40 CA264_20420 thiazole synthase 0.76 CA264_20435 phosphomethylpyrimidine synthase ThiC 0.61 3
Azospirillum brasilense Sp245 0.40 AZOBR_RS30960 thiazole synthase 0.67 AZOBR_RS07940 phosphomethylpyrimidine synthase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_3564 Uncharacterized enzyme of thiazole biosynthesis 0.74 Echvi_3567 thiamine biosynthesis protein ThiC 0.30 72
Pectobacterium carotovorum WPP14 0.37 HER17_RS20400 thiazole synthase 0.74 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.92 3
Vibrio cholerae E7946 ATCC 55056 0.37 CSW01_00355 thiazole synthase 0.71 CSW01_00335 phosphomethylpyrimidine synthase low > 62
Pedobacter sp. GW460-11-11-14-LB5 0.37 CA265_RS20180 thiazole synthase 0.75 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.38 43
Rahnella sp. WP5 0.36 EX31_RS16795 thiazole synthase 0.73 EX31_RS16815 phosphomethylpyrimidine synthase ThiC low > 89
Kangiella aquimarina DSM 16071 0.36 B158DRAFT_0291 thiazole-phosphate synthase 0.72 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.95 3
Shewanella sp. ANA-3 0.36 Shewana3_1940 thiG thiazole synthase (RefSeq) 0.70 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) low > 73
Dickeya dianthicola ME23 0.36 DZA65_RS01195 thiazole synthase 0.72 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.89 2
Ralstonia sp. UNC404CL21Col 0.36 ABZR87_RS04800 thiazole synthase 0.74 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC — —
Paraburkholderia sabiae LMG 24235 0.35 QEN71_RS27930 thiazole synthase 0.78 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC — —
Ralstonia solanacearum PSI07 0.35 RPSI07_RS23435 thiazole synthase 0.74 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.35 GFF4202 Thiazole biosynthesis protein ThiG 0.72 GFF4198 Thiamin biosynthesis protein ThiC low > 78
Dickeya dadantii 3937 0.35 DDA3937_RS01155 thiazole synthase 0.73 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.82 2
Escherichia coli ECOR38 0.35 HEPCGN_12030 thiG thiazole synthase 0.72 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC low > 85
Klebsiella michiganensis M5al 0.35 BWI76_RS01535 thiazole synthase 0.71 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.71 1
Escherichia coli BW25113 0.35 b3991 thiG thiamin biosynthesis, thiazole moiety (VIMSS) 0.72 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.94 1
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS09925 thiazole synthase 0.74 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC — —
Alteromonas macleodii MIT1002 0.35 MIT1002_00093 Thiazole synthase 0.71 MIT1002_00097 Phosphomethylpyrimidine synthase 0.99 1
Escherichia coli ECRC62 0.35 BNILDI_05985 thiG thiazole synthase 0.72 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC — —
Shewanella amazonensis SB2B 0.35 Sama_1856 thiG thiazole synthase (RefSeq) 0.72 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) low > 62
Escherichia coli BL21 0.35 ECD_03867 thiamine biosynthesis ThiGH complex subunit 0.72 ECD_03871 phosphomethylpyrimidine synthase low > 60
Escherichia coli ECOR27 0.35 NOLOHH_05540 thiG thiazole synthase 0.72 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.35 OHPLBJKB_04060 Thiazole synthase 0.72 OHPLBJKB_04056 Phosphomethylpyrimidine synthase low > 73
Ralstonia solanacearum UW163 0.35 UW163_RS03655 thiazole synthase 0.74 UW163_RS03640 phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC101 0.35 MCAODC_03895 thiG thiazole synthase 0.72 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC99 0.35 KEDOAH_14765 thiG thiazole synthase 0.72 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC101 0.35 OKFHMN_13395 thiG thiazole synthase 0.72 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC — —
Ralstonia solanacearum GMI1000 0.35 RS_RS00535 thiazole synthase 0.74 RS_RS00555 phosphomethylpyrimidine synthase — —
Escherichia coli ECRC98 0.35 JDDGAC_17020 thiG thiazole synthase 0.72 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC102 0.35 NIAGMN_11145 thiG thiazole synthase 0.72 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC — —
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS17775 thiazole synthase 0.77 BPHYT_RS13220 phosphomethylpyrimidine synthase — —
Bacteroides ovatus ATCC 8483 0.35 BACOVA_02359 thiazole biosynthesis protein ThiG 0.58 BACOVA_02358 thiamine biosynthesis protein ThiC 0.85 4
Mucilaginibacter yixingensis YX-36 DSM 26809 0.35 ABZR88_RS08825 thiazole synthase 0.75 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.93 1
Phocaeicola vulgatus CL09T03C04 0.35 HMPREF1058_RS03285 thiazole synthase 0.58 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.91 3
Escherichia fergusonii Becca 0.35 EFB2_04621 Thiazole synthase 0.72 EFB2_04617 Phosphomethylpyrimidine synthase low > 86
Phocaeicola dorei CL03T12C01 0.35 ABI39_RS17755 thiazole synthase 0.58 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.83 4
Paraburkholderia graminis OAS925 0.35 ABIE53_003714 thiazole synthase 0.77 ABIE53_002857 phosphomethylpyrimidine synthase — —
Enterobacter asburiae PDN3 0.35 EX28DRAFT_4532 Uncharacterized enzyme of thiazole biosynthesis 0.72 EX28DRAFT_4536 phosphomethylpyrimidine synthase low > 76
Dickeya dianthicola 67-19 0.35 HGI48_RS01150 thiazole synthase 0.72 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.84 1
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_05639 thiazole-phosphate synthase 0.77 H281DRAFT_00395 hydroxymethylpyrimidine synthase — —
Shewanella loihica PV-4 0.35 Shew_2092 thiazole biosynthesis family protein (RefSeq) 0.74 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) low > 60
Shewanella oneidensis MR-1 0.35 SO2441 thiG thiG protein (NCBI ptt file) 0.71 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.50 2
Escherichia coli Nissle 1917 0.34 ECOLIN_RS23020 thiazole synthase 0.72 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC low > 52
Serratia liquefaciens MT49 0.34 IAI46_01300 thiazole synthase 0.73 IAI46_01320 phosphomethylpyrimidine synthase ThiC low > 86
Cupriavidus basilensis FW507-4G11 0.34 RR42_RS01305 thiazole synthase 0.73 RR42_RS01290 thiamine biosynthesis protein ThiC — —
Bacteroides thetaiotaomicron VPI-5482 0.34 BT0651 thiamine biosynthesis protein ThiG (NCBI ptt file) 0.58 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.49 1
Variovorax sp. OAS795 0.34 ABID97_RS15315 thiazole synthase 0.68 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC low > 91
Enterobacter sp. TBS_079 0.34 MPMX20_00213 Thiazole synthase 0.72 MPMX20_00217 Phosphomethylpyrimidine synthase low > 85
Bacteroides stercoris CC31F 0.34 HMPREF1181_RS14680 thiazole synthase 0.58 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.32 22
Erwinia tracheiphila SCR3 0.34 LU632_RS00950 thiazole synthase 0.72 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC low > 74
Variovorax sp. SCN45 0.34 GFF1188 Thiazole synthase (EC 2.8.1.10) 0.69 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.85 4
Rhodopseudomonas palustris CGA009 0.33 TX73_018530 thiazole synthase 0.65 TX73_018540 phosphomethylpyrimidine synthase ThiC — —
Phaeobacter inhibens DSM 17395 0.33 PGA1_c09070 thiazole biosynthesis protein ThiG 0.67 PGA1_c09110 thiamine biosynthesis protein ThiC 0.94 1
Hydrogenophaga sp. GW460-11-11-14-LB1 0.32 GFF246 Thiazole biosynthesis protein ThiG 0.68 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Agrobacterium fabrum C58 0.31 Atu2566 thiamin biosynthesis ThiG 0.65 Atu2569 thiamine biosynthesis protein low > 89
Pantoea sp. MT58 0.31 IAI47_20700 thiazole synthase 0.73 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.34 68
Acidovorax sp. GW101-3H11 0.31 Ac3H11_1059 Thiazole biosynthesis protein ThiG 0.67 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Bosea sp. OAE506 0.30 ABIE41_RS20185 thiazole synthase 0.63 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC — —
Dinoroseobacter shibae DFL-12 0.28 Dshi_0912 thiazole biosynthesis family protein (RefSeq) 0.65 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) — —
Sinorhizobium meliloti 1021 0.27 SM_b20617 thiazole synthase 0.65 SM_b20615 thiamine biosynthesis protein ThiC — —

Not shown: 5 genomes with orthologs for PP_5104 only; 4 genomes with orthologs for PP_4922 only